Abstract：
:An object-oriented approach has been applied to the different stages involved in developing a knowledge base about insulin metabolism. At an early stage the separation of terminological and assertional knowledge was made. The terminological component was developed by medical experts and represented in CORE. An object-oriented knowledge acquisition process was applied to the assertional knowledge. A frame description is proposed which includes features like states and events, inheritance and collaboration. States and events are formalized with qualitative calculus. The terminological knowledge was very useful in the development of the assertional component. It assisted in understanding the problem domain, and in the implementation stage, it assisted in building good inheritance hierarchies.
journal_name
Artif Intell Medjournal_title
Artificial intelligence in medicineauthors
Ensing M,Paton R,Speel PH,Rada Rdoi
10.1016/0933-3657(94)90025-6subject
Has Abstractpub_date
1994-12-01 00:00:00pages
459-82issue
6eissn
0933-3657issn
1873-2860journal_volume
6pub_type
杂志文章abstract：OBJECTIVE:This paper proposes a novel method for the extraction and classification of individual motor unit action potentials (MUAPs) from intramuscular electromyographic signals. METHODOLOGY:The proposed method automatically detects the number of template MUAP clusters and classifies them into normal, neuropathic or ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2005.09.002
更新日期：2006-05-01 00:00:00
abstract：:As part of a plan to promote semi-automatic knowledge acquisition for the medical consultant system CADIAG-II/RHEUMA, this study sought to explore and cope with the variability of results that may be anticipated when performing knowledge acquisition with patient data from different patient settings. Patient data were ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(02)00025-8
更新日期：2002-07-01 00:00:00
abstract：:Rough sets (Pawlak Z. Rough Sets: Theoretical Aspects of Reasoning about Data, Dordrecht: Kluwer Academic Publishers, 1991) is a relatively new approach to representing and reasoning with incomplete and uncertain knowledge. This article introduces the basic concepts of rough sets and Boolean reasoning (Brown FM. Boole...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(98)00051-7
更新日期：1999-02-01 00:00:00
abstract：CONTEXT:Temporal information plays a crucial role in medicine, so that in medical informatics there is an increasing awareness that suitable database approaches are needed to store and support it. Specifically, a great amount of clinical data (e.g., therapeutic data) are periodically repeated. Although an explicit trea...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2012.03.002
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVE:One of the major topics towards robot consciousness is to give a robot the capabilities of self-consciousness. We propose that robot self-consciousness is based on higher order perception of the robot, in the sense that first-order robot perception is the immediate perception of the outer world, while higher ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2008.07.003
更新日期：2008-10-01 00:00:00
abstract：:Manual delineation of vestibular schwannoma (VS) by magnetic resonance (MR) imaging is required for diagnosis, radiosurgery dose planning, and follow-up tumor volume measurement. A rapid and objective automatic segmentation method is required, but problems have been encountered due to the low through-plane resolution ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2020.101911
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND AND MOTIVATION:DNA microarray technology has made it possible to determine the expression levels of thousands of genes in parallel under multiple experimental conditions. Genome-wide analyses using DNA microarrays make a great contribution to the exploration of the dynamic state of genetic networks, and furt...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2005.02.007
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVE:Recently, much research has been proposed using nature inspired algorithms to perform complex machine learning tasks. Ant colony optimization (ACO) is one such algorithm based on swarm intelligence and is derived from a model inspired by the collective foraging behavior of ants. Taking advantage of the ACO in...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2009.03.004
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVE:Connect-Four, a new sensorimotor rhythm (SMR) based brain-computer interface (BCI) gaming application, was evaluated by four severely motor restricted end-users; two were in the locked-in state and had unreliable eye-movement. METHODS:Following the user-centred approach, usability of the BCI prototype was ev...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2013.08.001
更新日期：2013-10-01 00:00:00
abstract：:This work presents a hybrid expert system (HES) intended to minimise some complex problems pervasive to knowledge engineering such as: the knowledge elicitation process, known as the bottleneck of expert systems; the choice of a model for knowledge representation to codify human reasoning; the number of neurons in the...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(00)00090-7
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:Protein homology prediction between protein sequences is one of critical problems in computational biology. Such a complex classification problem is common in medical or biological information processing applications. How to build a model with superior generalization capability from training samples is an ess...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2005.02.003
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVES:A well-developed appointment system can help increase the utilization of medical facilities in an outpatient department. This paper outlines the development of an appointment system that can make an outpatient department work more efficiently and improve patient satisfaction level. METHODS:A Markov decision...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2014.12.002
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:In this paper a new nonlinear system identification approach is developed for dynamical quantification of cardiovascular regulation. This approach is specifically focused on the identification of the heart rate (HR) baroreflex mechanism. The principal objective of this paper is to improve the model accuracy i...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2011.01.002
更新日期：2011-05-01 00:00:00
abstract：:We introduce a novel approach to couple temporal similarity with spatial neighborhood information. This is achieved by concatenating the K nearest, spatially contiguous neighbors of a pixel time-course (TC) of T time-instances. This produces a new TC of (K+1)T time instances. Depending on how "nearest" is defined, we ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(02)00005-2
更新日期：2002-05-01 00:00:00
abstract：OBJECTIVE:In the modern healthcare system, rapidly expanding costs/complexity, the growing myriad of treatment options, and exploding information streams that often do not effectively reach the front lines hinder the ability to choose optimal treatment decisions over time. The goal in this paper is to develop a general...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2012.12.003
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:High dose radiation has been well known for increasing the risk of carcinogenesis. However, the understanding of biological effects of low dose radiation is limited. Low dose radiation is reported to affect several signaling pathways including deoxyribonucleic acid repair, survival, cell cycle, cell growth, a...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2010.04.001
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:This paper presents a novel rule-based fuzzy classification methodology for survival/mortality prediction in severe burnt patients. Due to the ethical aspects involved in this medical scenario, physicians tend not to accept a computer-based evaluation unless they understand why and how such a recommendation i...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2013.12.006
更新日期：2014-03-01 00:00:00
abstract：:In this paper, we propose an approach for managing clinical guidelines. We outline a modular architecture, allowing us to separate two conceptually distinct aspects: the representation (and acquisition) of clinical guidelines and their execution. We propose an expressive formalism, which allows one to deal with the co...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章,评审
doi：10.1016/s0933-3657(01)00087-2
更新日期：2001-11-01 00:00:00
abstract：:Problems involved in the specification of large expert systems are discussed. In the specification of causal probabilistic networks conditional probability tables for all nodes have to be provided. These conditional probability tables can often be described by models that specify the nature of interaction between node...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/0933-3657(93)90029-3
更新日期：1993-06-01 00:00:00
abstract：:The optical device LIPOMETER allows for non-invasive, quick, precise and safe determination of subcutaneous fat distribution, so-called subcutaneous adipose tissue topography (SAT-Top). In this paper, we show how the high-dimensional SAT-Top information of women with type-2 diabetes mellitus (non-insulin-dependent dia...
journal_title：Artificial intelligence in medicine
pub_type： 临床试验,杂志文章
doi：10.1016/s0933-3657(99)00017-2
更新日期：1999-10-01 00:00:00
abstract：AIM:A new automatic method for detecting specific points and lines (straight and curves) in dental panoramic radiographies (orthopantomographies) is proposed, where the human knowledge is mapped to the automatic system. The goal is to compute relevant mandibular indices (Mandibular Cortical Width, Panoramic Mandibular ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2020.101816
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:The aim of this paper is to study the feasibility and the performance of some classifier systems belonging to family of instance-based (IB) learning as second-opinion diagnostic tools and as tools for the knowledge extraction phase in the process of knowledge discovery in clinical databases. MATERIALS AND ME...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2011.04.002
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:Recently, fuzzy soft sets-based decision making has attracted more and more interest. Although plenty of works have been done, they cannot provide the uncertainty or certainty of their results. To manage uncertainty is one of the most important and toughest tasks of decision making especially in medicine. In ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2016.04.004
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:Patients who are readmitted to an intensive care unit (ICU) usually have a high risk of mortality and an increased length of stay. ICU readmission risk prediction may help physicians to re-evaluate the patient's physical conditions before patients are discharged and avoid preventable readmissions. ICU readmi...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2018.08.004
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVES:The objective of this study is to devise a modelling strategy for attaining in-silico models replicating human physiology and, in particular, the activity of the autonomic nervous system. METHOD:Discrete Multiphysics (a multiphysics modelling technique) and Reinforcement Learning (a Machine Learning algorit...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2019.06.005
更新日期：2019-07-01 00:00:00
abstract：:Melanoma is the most dangerous skin cancer and early diagnosis is the key factor in its successful treatment. Well-trained dermatologists reach a diagnosis via visual inspection, and reach sensitivity and specificity levels of about 80%. Several computerised diagnostic systems were reported in the literature using dif...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(02)00087-8
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:Although numerous studies related to cancer survival have been published, increasing the prediction accuracy of survival classes still remains a challenge. Integration of different data sets, such as microRNA (miRNA) and mRNA, might increase the accuracy of survival class prediction. Therefore, we suggested a...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2014.06.003
更新日期：2014-09-01 00:00:00
abstract：:Traditional Chinese medicine has developed over more than 4000 years. A tremendous amount of medical knowledge has been accumulated, among which herbal drugs and formulae are an important portion. This paper presents an ontology for traditional Chinese drugs and formulae, and an ontology-based system for extracting kn...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2004.01.015
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:There is an ongoing research effort devoted to characterize the signal regularity metrics approximate entropy (ApEn) and sample entropy (SampEn) in order to better interpret their results in the context of biomedical signal analysis. Along with this line, this paper addresses the influence of abnormal spikes ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2011.06.007
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:While EIRA has proved to be successful in the detection of anomalous patient responses to treatments in the Intensive Care Unit, it could not describe to clinicians the rationales behind the anomalous detections. The aim of this paper is to address this problem. METHODS:Few attempts have been made in the pas...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2013.02.003
更新日期：2013-05-01 00:00:00
