Abstract:
:Feeding mice a diet deficient in n-3 fatty acids for three generations resulted in a 53% decrease in docosahexaenoic acid (DHA, 22:6n-3) in the brain. Maternal pup retrieval and social learning of a food preference are both tasks based on olfactory function. All dams made contact more readily with pups of their own dietary group, and animals of both dietary groups demonstrated the ability to learn a food preference through exposure to a conspecific that had previously eaten the food. Both groups showed similar ability to learn the location of the hidden platform in the Morris water maze, while the n-3 deficient animals were marginally faster in locating the platform on the cued trial. They were also more active when tested in the open field. While they did not differ in their duration of immobility in a forced swimming test, the deficient animals did have longer paw-lick latencies on a hot plate. Thus, in this study a significant reduction in brain n-3 fatty acid composition, while associated with some indications of change in emotional reactivity, did not impair olfactory function or learning of either a latent or spatial nature.
journal_name
Dev Psychobioljournal_title
Developmental psychobiologyauthors
Wainwright PE,Huang YS,Coscina DV,Lévesque S,McCutcheon Ddoi
10.1002/dev.420270705subject
Has Abstractpub_date
1994-11-01 00:00:00pages
467-87issue
7eissn
0012-1630issn
1098-2302journal_volume
27pub_type
杂志文章abstract::Autism is an early onset neurodevelopmental disorder characterized by disruption of early social interaction. Although the social disability of autism remains the central defining feature of the condition, mechanisms that might account for this disability remain poorly understood. This paper briefly reviews some aspec...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.20556
更新日期:2011-07-01 00:00:00
abstract::Very-low-birth-weight infants are at much higher risk for cognitive and language delays but the nature of such deficits is not clearly understood. Given increasing rates of prematurity and infants born very-low-birth-weight, examination of mechanisms that underlie poorer developmental outcome is essential. We investig...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20278
更新日期:2008-03-01 00:00:00
abstract::Lactating females of 2 lines of mice selectively bred for long (LS) and short (SS) ethanol-induced sleep time (a measure of alcohol tolerance) consumed either tap water or 10% ethanol in tap water on Days 2-14 postpartum. Effects of genotype and neonatal treatment on offspring open-field behavior, alcohol-induced slee...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420120303
更新日期:1979-05-01 00:00:00
abstract::The reactions of 4 infants each at ages 10, 15, and 20 months were recorded on videotape as they responded to their own simultaneous video image, their own previously taped video image, the image of a control infant, and that of a female stranger. The subjects' responses were coded by 2 research assistants, ignorant o...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420100102
更新日期:1977-01-01 00:00:00
abstract::Maternal touch profoundly regulates infant neural and behavioral development, and supports learned odor associations necessary for infant attachment. Endogenous opioids are well characterized to mediate the calming and analgesic properties of maternal touch; yet their role in learned odor-touch associations is unknown...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20107
更新日期:2006-01-01 00:00:00
abstract::How the intrinsic sequence structure of neonatal mouse pup ultrasonic vocalization (USV) and maternal experiences determine maternal behaviors in mice is poorly understood. Our previous work showed that pups with a Tbx1 heterozygous (HT) mutation, a genetic risk for autism spectrum disorder (ASD), emit altered call se...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.22006
更新日期:2021-01-01 00:00:00
abstract::Habituation of defensive attacks directed toward a threatening stimulus was investigated in neonatal garter snakes. The focus of the experiments was on differential effects of a simple experimental process in relation to species, litter, sex, and individual. In Experiment 1 newborn Thamnophis melanogaster from four li...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420220507
更新日期:1989-07-01 00:00:00
abstract::While the influence of the mother's voice on neonatal heart-rate response and its relevant activity on cerebral cortex and the autonomic nervous system (ANS) are well known, few studies have assessed its influence on respiratory activity. We investigated the relationship among the respiration rate, the delta wave ampl...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21596
更新日期:2018-03-01 00:00:00
abstract::This study tested predictions regarding two hypothesized maternal immune responses influencing sexual orientation: one affecting homosexual males with high fraternal birth order and another affecting firstborn homosexual individuals whose mothers experience repeated miscarriage after the birth of the first child. Low ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21254
更新日期:2015-01-01 00:00:00
abstract::This study examined the role of sensorimotor system noise in the organization of the force output of the thumb and index finger and the coordination between the two digits in an isometric pinch grip force task as a function of age (6, 8, 10, 18-22 years), feedback condition (with and without visual feedback informatio...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.10051
更新日期:2002-11-01 00:00:00
abstract::The ontogenesis of the effect of lithium on suckling behavior was assessed by administering lithium carbonate directly and acutely to 15-, 20-, 30-, and 35-day-old rat pups. Lithium significantly interfered with nipple attachment in 15-day-old rat pups in a dose-dependent pattern, but it facilitated attachment at some...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420220805
更新日期:1989-12-01 00:00:00
abstract::Despite evidence that acute stress impairs attention in adults, there has been minimal research in children. Here, the effects of acute stress on Go/No-go performance were examined in young children (M age = 5.41 years). Given the critical role of the parent-child relationship to children's self-regulatory development...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21915
更新日期:2020-05-01 00:00:00
abstract::We examined regional brain electrical activity (EEG), heart rate, and subjective responses at rest and during the presentation of videoclips designed to elicit a range of emotions (e.g., sadness, anger, happiness, fear) among a sample of healthy 4-year-old children selected for temperamental shyness. We found that shy...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20133
更新日期:2006-04-01 00:00:00
abstract::Mallard ducklings (Anas platyrhynchos) inhibit their vocal and locomotor behavior upon hearing the maternal alarm call of their species. This study assesses the effects of varying acoustic features of alarm calls on the ducklings' freezing response (i.e., vocal and locomotor inhibition). Domestic mallard (Peking) duck...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420190402
更新日期:1986-07-01 00:00:00
abstract::Passive avoidance learning was studied in young rats 7-20 days old, in control conditions and after bilateral injections of physostigmine into the lateral amygdaloid nucleus. Acquisition in controls was possible from postnatal Day 8 on, progressed markedly after Day 11, and nearly reached maturity by Day 20. Physostig...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420210606
更新日期:1988-09-01 00:00:00
abstract::Spontaneous eye blinking has been studied in clinical and neuropharmacological research in adult humans and nonhuman primates as a putative index of central dopamine system activity. One purpose of this review is to provide a general overview of the research on spontaneous eye blinking with an emphasis on the relation...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.10162
更新日期:2004-03-01 00:00:00
abstract:INTRODUCTION:The long allele of the DRD4 gene can confer different behavioral and emotional phenotypes depending upon environmental exposure, although the physiological changes underlying these phenotypes are not fully known. We sought to extend this work by assessing the interaction of the DRD4 gene and exposure to pe...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21539
更新日期:2017-09-01 00:00:00
abstract::This study examined the direct and interactive effects of infants' respiratory sinus arrhythmia (RSA) and maternal depressive symptoms (MDS) during the first 6 months of life in the prediction of children's sleep problems at age 18 months. Participants included 156 children and their mothers who were followed from 3 t...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21480
更新日期:2017-03-01 00:00:00
abstract::Animal personality has been extensively studied from a functional and evolutionary point of view. Less attention has been paid to the development of personality, its phenotypic plasticity, and the influence of manipulation of early environmental factors. Here we describe the effects of manipulating the sex ratio of th...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20586
更新日期:2011-09-01 00:00:00
abstract::We examined associations between children's cognitive performance and both basal respiratory sinus arrhythmia (RSA) and RSA regulation to a reaction time task. Cognitive performance was examined in the lab via standardized tests of cognitive functioning (Woodcock-Johnson III) and a reaction time task. Results suggest ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20361
更新日期:2009-04-01 00:00:00
abstract::The effects of short-term bilateral naris occlusion (inducing olfactory deprivation) on mother-pup interactions, suckling behavior and hormonal status during post-natal development in Wistar rats were studied. Bilateral naris occlusion was performed on 8-day-old rat pups and its effects were evaluated at Day 9 and at ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20523
更新日期:2011-04-01 00:00:00
abstract::Puberty marks the beginning of a period of dramatic physical, hormonal, and social change. This instability has made adolescence infamous as a time of "storm and stress" and it is well-established that stress during adolescence can be particularly damaging. However, prior stress may also shape the adolescent experienc...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21765
更新日期:2019-07-01 00:00:00
abstract::Adolescence is a time involving a series of changes in the use of appetitive reinforcers like food, as well as neuroendocrine changes like those taking place in the mesolimbic dopamine function. Social isolation from postnatal day 21 to 36 in rats leads to behavioral and neurophysiological alterations such as increase...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21273
更新日期:2015-03-01 00:00:00
abstract:UNLABELLED:Autonomic control of blood pressure (BP) and heart rate (HR) was tested in offspring of rat dams that were unmanipulated (controls) or exposed repeatedly to either (1) Postnatal restraint, (2) Postnatal s.c. injections of alkaline saline, or (3) Prenatal s.c. alkaline saline. Under urethane anesthesia, BP wa...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420230806
更新日期:1990-12-01 00:00:00
abstract::Schizophrenia is a complex neuropsychiatric disorder characterized by hallucinations, delusions, anhedonia, flat affect and cognitive impairments. The aim of this study was to propose a prenatal treatment with ketamine, a psychedelic drug that acts as a non-competitive inhibitor of glutamate NMDA receptors, as a neuro...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21586
更新日期:2018-01-01 00:00:00
abstract::In three experiments the effects of dopamine receptor antagonists on response-contingent punishment and autoshape learning of 1- and 4-day-old chicks were determined. In the first two experiments, 1- or 4-day-old chicks (N = 120) were trained to key-peck for heat reward and then injected intraperitoneally (ip) with ei...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420230205
更新日期:1990-03-01 00:00:00
abstract::Adolescent intermittent ethanol (AIE) exposure in the rat results in a retention of adolescent-like responsiveness to ethanol into adulthood characterized by enhanced sensitivity to socially facilitating and decreased sensitivity to socially suppressing and aversive effects. Similar pattern of responsiveness to social...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.22099
更新日期:2021-01-28 00:00:00
abstract::Although most mammals grow up in the company of same or different age sibs (or half sibs), surprisingly little attention has been given to how relations among them might influence the development of individual differences in morphology, physiology, and behavior. Here we review evidence from our work on domestic and wi...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.20535
更新日期:2011-09-01 00:00:00
abstract::The effect of a positive first-time experience on adrenocortical activity was examined in 48 6- to 13-month-old infants who took part in two sessions of a YMCA-like mother-infant swim class. Experience was manipulated by comparing Novice swimmers with infants who previously had taken a swim class, and by examining res...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420250503
更新日期:1992-07-01 00:00:00
abstract::The ontogeny of behavioral and heart-rate orienting responses to a novel olfactory stimulus was examined in three experiments. The results of Experiment 1 demonstrated that behavioral responses to the olfactory stimulus were observed as early as Day 1, although heart-rate deceleration in response to the stimulus was n...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420240102
更新日期:1991-01-01 00:00:00