Mother-pup interactions during a short olfactory deprivation period in young rats.

Abstract:

:The effects of short-term bilateral naris occlusion (inducing olfactory deprivation) on mother-pup interactions, suckling behavior and hormonal status during post-natal development in Wistar rats were studied. Bilateral naris occlusion was performed on 8-day-old rat pups and its effects were evaluated at Day 9 and at Day 15. The narins opened spontaneously between Day 12 and 14. Olfactory-deprived pups exhibited a greater level of corticosterone at both ages versus untreated or sham animals. Olfactory deprivation via naris occlusion, in young rats, alters mother-pup interactions with a decrease in the duration of mother-pup retrieving and an increase in pup licking. Olfactory-deprived pups showed also a lower mean duration of nursing and a decrease in nipple attachment, which appeared related to difficulties in finding the nipple. Olfactory-deprived pups had difficulty recognizing their nest. These behavioral alterations were accompanied by a diminution in milk ingested and growth retardation associated with a reduced level of thyroxin at both 9 and 15 days of age.

journal_name

Dev Psychobiol

authors

Gelhaye M,Padzys GS,Olry JC,Thornton SN,Martrette JM,Trabalon M

doi

10.1002/dev.20523

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

303-16

issue

3

eissn

0012-1630

issn

1098-2302

journal_volume

53

pub_type

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