Abstract：
:Studies of acute exacerbations of chronic bronchitis (EXCB) included in the approval documents of levofloxacin (LVF) were reviewed in light of the good conditions of use defined by the French marketing approval and the AFSSAPS recommendations. The approval documents included two American studies comparing LVF 500 mg/d for 5-7 days with cefaclor 750 mg/d for 7-10 days or cefuroxime axetil (CXM) 500 mg/d for 7-10 days. A new descriptive analysis of efficacy was performed on a population meeting the recommendation criteria for antibiotic treatment in patients with clinical signs of obstruction. This analysis was stratified by number of risk factors (RF) for the following aggravating conditions: age above 65 years, diabetes or corticosteroid therapy. In the American studies, clinical efficacy, measured by rate of success in the total population, in the EXCB population requiring antibiotic therapy with or without risk factors, and in the EXCB population with at least one and at least two of the above-cited risk factors was 93.4% (351/376), 93.0% (268/288), 90.4% (122/135) and 94.4% (34/36) respectively with LVF and 92.2% (354/384), 92.5% (273/295), 87.7% (128/146) and 79.3% (23/29) respectively with the compared drugs. In the European study, the clinical efficacy in the total population, in the EXCB population requiring antibiotic therapy with or without risk factors, and in the EXCB population with at least one and at least two of the above-cited risk factors was 81.9% (195/238), 82.4% (182/221), 78.9% (112/142) and 75.0% (27/36) respectively with LVF and 72.5% (166/229), 74.0% (154/208), 73.1% (95/130) and 58.3% (21/36) respectively with the compared drugs. The efficacy of levofloxacin is thus confirmed for EXCB with signs of obstruction. When stratifying for RF, the efficacy of LVG persists with increasing numbers of RF, a result not observed with the compared drugs.
journal_name
Rev Pneumol Clinjournal_title
Revue de pneumologie cliniqueauthors
Zuck P,Veyssier P,Brumpt Idoi
10.1016/s0761-8417(04)72112-4subject
Has Abstractpub_date
2004-11-01 00:00:00pages
269-77issue
5 Pt 1eissn
0761-8417issn
1776-2561pii
MDOI-RPC-11-2004-60-5-0761-8417-101019-ART4journal_volume
60pub_type
杂志文章abstract：:Pulmonary alveolar proteinosis is a rare disease characterized by the accumulation of granular lipoproteinaceous material within the alveoli; the interstitium is preserved. We report the case of a 27-year-old patient hospitalized for exploration of asymptomatic bilateral interstitial syndrome. Neither the radiographic...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/s0761-8417(05)84849-7
更新日期：2005-10-01 00:00:00
abstract：:The presence of non-caseating epitheloid cell granulomas in biopsy material is still one of the most important factors in establishing the diagnosis of sarcoidosis. Since Carlens introduced mediastinoscopy as a diagnostic procedure in these cases the use of liver biopsy or bronchoscopic biopsy has decreased because of...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The onset of non-cardiogenic acute pulmonary oedema during resection of a vesical paraganglioma is reported. Such oedema may be caused by the intravascular injection of massive doses of catecholamines in the animal. Aetiopathogenic mechanisms are suggested on the basis of experimental data. ...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Perthes syndrome, or traumatic asphyxia syndrome, is a rare clinical entity, associating cyanosis, cervicofacial petechiae and subconjunctival hemorrhage. It is usually secondary to chest trauma, but can occur in any situation of abrupt rise in intrathoracic pressure with closed glottis. In this paper, we present a ca...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2016.08.002
更新日期：2016-12-01 00:00:00
abstract：UNLABELLED:Exacerbations of chronic obstructive pulmonary disease (COPD) have an inflammatory component in addition to the possible infectious component. The antiinflammatory properties of fenspiride (Pneumorel(R) 80 mg) should be evaluated in this frequent clinical situation. OBJECTIVES:Assess the supplementary thera...
journal_title：Revue de pneumologie clinique
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2000-02-01 00:00:00
abstract：INTRODUCTION:Necrotizing fasciitis is a rapidly progressive and often fatal infection of the soft-tissue fascia deep to the skin but superficial to the muscles. We report a case of necrotizing fasciitis of the anterior chest wall complicating a percutaneous needle biopsy. CASE:A 49-year-old diabetic patient, presented...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/s0761-8417(07)92652-8
更新日期：2007-09-01 00:00:00
abstract：:Sarcoidosis is a diffuse granulomatosis predominately with mediastino-pulmonary localizations. A wide range of extrathoracic localizations can also occur and when they are the initial manifestation, may lead to misdiagnosis. We observed a rare case of peritoneal sarcoidosis revealed by a surgical emergency. ...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The presence of D-dimers in the serum reflects fibrin formation and lysis. If the serum D-dimer level is lower than a threshold level which depends on the assay technique (usually 500 micrograms/l), pulmonary embolism can be excluded with a predictive value of 95%. This makes D-dimer assay an ideal screening tool for ...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1998-07-01 00:00:00
abstract：:Chemotherapy (CT) combined with surgery in non-small cell lung cancers has been studied for a number of years. It can be used prior to or following surgery (adjuvant). A long rather unfruitful period ended with the meta-analysis of the Non-Small Cell Cancer Collaborative Group, published in the British Medical Journal...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：2004-11-01 00:00:00
abstract：:A study devised to evaluate the effects of chronic exposure to tobacco smoke on the health of a population of non-smokers was conducted in a prison. Fourteen volunteers among male, non-smoking prisoners in good health and without history of lung disease were put for thirty days in a cell that was already occupied by t...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：:Mucormycosis is a rare, devastating, opportunistic fungal infection, which occurs principally in some particular conditions, specially in non-controlled diabetic patients, notably during keratoacidosis. We report two cases in 62 and 72 year-old diabetic women. In both cases, histologic examination of endobronchial bio...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/s0761-8417(06)75412-8
更新日期：2006-02-01 00:00:00
abstract：:Tracheobronchomegaly is defined as a dilatation of the trachea and the large bronchi. It may occur as a familial condition or in association with a connective tissue disease, e.g. Ehlers-Danlos syndrome. Tracheobronchomegaly occurs late in adults. The predominant symptoms are bronchial irritation and recurrent broncho...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：2002-02-01 00:00:00
abstract：:The pleural lymphatic system has a great absorption capacity. Its most known function is fluid resorption. The pleura which cover the lungs (visceral pleura), the mediastinum, diaphragm and thoracic wall (parietal pleura) are formed by a mesothelial cell layer (mesothelium). This permeable layer is in direct contact w...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：10.1016/j.pneumo.2013.01.006
更新日期：2013-06-01 00:00:00
abstract：:Despite the dramatic decline in the incidence of tuberculosis during the last decades, the disease remains a significant public health problem especially in developing countries. Chest wall tuberculosis is a very rare location. Clinically, it can present as a pyogenic abscess or soft tumor, making diagnosis difficult,...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2014.12.006
更新日期：2015-10-01 00:00:00
abstract：:Large calcium deposits can occur in neuroendocrine tumours of the bronchi and have been observed more frequently with the development of tomodensitometry which is now used for the diagnosis of calcified lung tumours including neuroendocrine tumours. The knowledge of such calcified images should not however mask the po...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:The bronchomotor properties of calcium antagonists were investigated in 10 patients with paroxysmal asthma, using a double-blind, cross-over method. Each patient received, in random order, either a placebo (5% glucose solution) or bepridil (2 mg/kg) administered by intravenous infusion over 30 min. There were no chang...
journal_title：Revue de pneumologie clinique
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1986-01-01 00:00:00
abstract：:Infectious complications are rarely observed in the course of sarcoidosis. Only small series or cases reports of infection are described in sarcoidosis. Corticosteroids-induced immune suppression, pulmonary fibrosis and T-CD4 lymphopenia, are often present. Pulmonary nocardiosis is an important cause of opportunistic ...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2012.12.001
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:Tuberculosis and human immunodeficiency virus infection are two major public health problems in sub-Saharan Africa. The aim of this study was to determine the prevalence of HIV infection in all clinical forms of TB and investigate the effects of HIV status on the evolution of tuberculosis. PATIENTS AND METH...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2012.10.001
更新日期：2012-12-01 00:00:00
abstract：:We report a case of angiolymphoid hyperplasia, or Castleman's pseudotumour, located in the chest and most unusually opposite an intercostal space. Pain led to the discovery of the tumour, the nature of which was discovered at surgery, and disappeared after surgical excision. No antigenic stimulus or local haemodynamic...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:We report a case of pulmonary carcinosarcoma. Surgery is required for this rare mixed type, biphasic tumor. It is generally considered to be a malignant formation issuing from a single cell line but with a two-way differentiation into epithelial and conjunctive components. There is a differentiation continuum between ...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The prevalence of smoking in France remains very high compared to other developed Western countries. The management of smoking in smokers is often limited to nicotinic substitution, whether medicated or linked to the use of electronic cigarettes or varenicline and advices more or less reliable or helpful. This strateg...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：10.1016/j.pneumo.2017.09.005
更新日期：2017-12-01 00:00:00
abstract：INTRODUCTION:Castleman's disease is a rare orphan disease. The prevalence is estimated at less than 1/100 000. Respirologists may encounter this disease when its thoracic manifestations occur. CASE REPORT:The authors report two cases of Castleman's disease with two different thoracic involvements. The first patient wa...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2008.12.004
更新日期：2009-04-01 00:00:00
abstract：:Constrictive pericarditis was diagnosed in four patients who presented respiratory impairment and pleural effusion, associated with right ventricular failure in two. The cause was probable tuberculosis in two cases, post-irradiation lesions in one and unknown in one. The diagnosis was suspected due to the normal heart...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1998-02-01 00:00:00
abstract：:We report 8 cases of thoracic actinomycosis, a disease which is now uncommon owing to the widespread use of antibiotics and which is caused by anaerobic filamentous bacteria living as saprophytes in natural cavities. Recent pathogenetic data, such as propagation by continuity or blood stream, as well as bacteriologica...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：:The authors studied 13 cases of arrhythmia following pneumonectomy in a series of 94 pneumonectomies performed in the Thoracic Surgery Unit. The arrhythmias essentially consisted of atrial fibrillation which was well tolerated haemodynamically. It generally occurred in ambulant patients on about the 5th postoperative ...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:The observation of 3 cases has prompted the authors to review the characteristics of vascular abnormalities that may be found in Behçet's disease. These lesions, the frequency of which has diversely been estimated, involve the veins more often than the arteries. Arterial lesions occur, after a varying length of time, ...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：:In order to determine the exact significance and origin of lactate dehydrogenases (LDH) present in pleural effusions, LDH and their enzymes were assayed in the serum and pleural fluid of 60 patients with wet pleurisy and in the main blood cells (haematocytes, polymorphonuclears mononuclears) found in pleural fluids. O...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：BACKGROUND:Asthma guidelines recommend combining inhaled corticosteroids and long-acting inhaled B2-agonists when inhaled corticosteroids alone are insufficient to achieve good control of the disease. OBJECTIVES:To determine in routine practice whether the fixed-dose fluticasone-salmeterol combination (FP/s) is as lea...
journal_title：Revue de pneumologie clinique
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-06-01 00:00:00
abstract：:Vitamin K antagonists are the mainstay for the treatment for venous thromboembolism. The optimum (VTE) course of oral anticoagulant therapy is determined according to the risk of recurrent VTE after stopping anticoagulant therapy and the risk of anticoagulant-related bleeding while on antivitamin K. The risk of recurr...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：10.1016/j.pneumo.2008.09.007
更新日期：2008-12-01 00:00:00
abstract：INTRODUCTION:In spite of recommendations of the highest level of proof (rank A), the respiratory rehabilitation remains very widely sub-prescribed by general practitioners, who are nevertheless in the front line in the care and the follow-up of the patients affected by BPCO. MATERIAL AND METHODS:Semi-qualitative study...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2017.03.002
更新日期：2017-06-01 00:00:00
