[Does D-dimer determination allow the exclusion of pulmonary embolism?].

Abstract:

:The presence of D-dimers in the serum reflects fibrin formation and lysis. If the serum D-dimer level is lower than a threshold level which depends on the assay technique (usually 500 micrograms/l), pulmonary embolism can be excluded with a predictive value of 95%. This makes D-dimer assay an ideal screening tool for ambulatory patients with suspected pulmonary embolism. Screening costs can be reduced in about one-third of the cases as other tests are not required. For routine practice, only ELISA tests have been validated for this indication, the sensitivity of latex tests being too low. D-dimer assay would be of little benefit for patients hospitalized for more than 24 for reasons other than suspected pulmonary embolism as specificity is very low in this population.

journal_name

Rev Pneumol Clin

authors

Bounameaux H

subject

Has Abstract

pub_date

1998-07-01 00:00:00

pages

144-8

issue

3

eissn

0761-8417

issn

1776-2561

pii

MDOI-RP-07-1998-54-3-0761-8417-101019-ART93

journal_volume

54

pub_type

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