[Early postoperative management and immunosuppressive treatment following lung transplantation].

Abstract:

:Lung transplantation is now considered a valid option in the management of end-stage respiratory failure. The postoperative period remains a key stage that will influence the average long-term prognosis of the patients. Primary graft failure, postoperative bleeding, infection, acute rejection and complications linked to the surgery, and to vascular or bronchial anastomoses, are risk factors for mortality and morbidity. These must be taken care of quickly via collaboration with the surgical team. The immunosuppressive treatment essential for tolerance induction with regard to the transplanted organ will be introduced during the intraoperative period and continued for life. The combination of a calcineurin inhibitor, an antiproliferative agent and corticosteroids remains the conventional procedure. The role of new molecules as mTor inhibitors remains to be determined.

journal_name

Rev Pneumol Clin

authors

Boussaud V

doi

10.1016/j.pneumo.2010.12.005

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

21-7

issue

1

eissn

0761-8417

issn

1776-2561

pii

S0761-8417(10)00185-9

journal_volume

67

pub_type

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