Nasal function and bronchial hyperresponsiveness to methacholine in children.

Abstract:

:The objective of the present study was to investigate nasal function by active anterior rhinomanometry with respect to spirometric data and bronchial hyperresponsiveness to methacholine in 9-year-old children. The study population consisted of 300 children (ages 8 to 11 years; mean, 9.3 years; 161 male, 139 female), who underwent basal rhinomanometry followed by a decongestion test and a lung function test consisting of spirometry and a methacholine provocation test. The flow values of the basal rhinomanometry showed a significant correlation with height and bronchial hyperresponsiveness. The consecutive decongestion test showed a marked increase in flow rates at each level, which was found to be significantly higher in children with bronchial hyperresponsiveness (p < 0.01). The spirometric data showed no influence on rhinomanometric values. These results suggest that nasal dysfunction and reactivity in terms of the decongestion test may be associated with bronchial hyperresponsiveness in children.

journal_name

Chest

journal_title

Chest

authors

Kiss D,Popp W,Horak F,Wagner C,Zwick H

doi

10.1378/chest.107.6.1582

subject

Has Abstract

pub_date

1995-06-01 00:00:00

pages

1582-4

issue

6

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)35778-6

journal_volume

107

pub_type

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