[Use of high-dosage chemotherapy with autologous hematopoietic stem cell transplantation as a first-line therapy for the patients with poor-prognosis testicular tumors].

Abstract:

BACKGROUND:High-dose chemotherapy followed by hematopoietic stem cell support can be used as a first-line treatment in patients with germ-cell tumor (GCT) with poor prognosis. Long-term survival rate is attained in 50% of these patients. The aim of this paper was to present the experience at the Department of Hematology, Military Medical Academy, with high-dose cytostatic therapy as first-line chemotherapy in GCT patients with poor prognosis. METHODS:Between 1997 and 2003, five patients with high-risk germ-cell tumors were treated with high-dosage chemotherapy followed by an autologous stem cell transplantation. All the patients were with non-seminomatous germ-cell tumors with mixed histology, and one was with extragonadal retroperitoneal germ-cell tumor. RESULTS:The follow-up period ranged from 8 to 33 months. Three patients achieved complete remision, two patients only partial remision, and one was not followed-up. One patient was with residual tumor resection, using retroperitoneal lymphadenectomy, after autologous stem cell transplantation. All the patients were treated according to standard protocols. CONCLUSION:Early high-dose chemotherapy associated with hematopoietic stem cell support as a first-line treatment in the patients with germ-cell tumor with a poor prognosis, represented an efficient treatment modality.

journal_name

Vojnosanit Pregl

journal_title

Vojnosanitetski pregled

authors

Marjanović S,Cerović S,Brajusković G

doi

10.2298/vsp0503213m

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

213-8

issue

3

eissn

0042-8450

issn

2406-0720

journal_volume

62

pub_type

杂志文章
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    abstract::Esophageal stapler transection was performed in 15 patients with bleeding from the dilated esophageal veins in the period 1984-1988. In 7 patients operated on as urgent cases due to prolonged uncontrolled bleeding, the mortality was high--71.4%, contrary to the group of electively operated patients in whom the mortali...

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    doi:

    authors: Duknić M,Cuk V

    更新日期:1990-01-01 00:00:00

  • Differentiation of human dendritic cells from monocytes in vitro using granulocyte-macrophage colony stimulating factor and low concentration of interleukin-4.

    abstract::Several laboratories have developed culture systems that allow the generation of large numbers of human dendritic cells (DC) from monocytes using granulocyte-macrophage colony stimulating factor (GM-CSF), and interleukin-4 (IL-4). In this work we provided evidence that GM-CSF (100 ng/ml) in combination with a low conc...

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    authors: Colić M,Jandrić D,Stojić-Vukanić Z,Antić-Stanković J,Popović P,Vasilijić S,Milosavljević P,Balint B

    更新日期:2003-09-01 00:00:00

  • Self-assessment of the quality of life of children and adolescents in the child welfare system of Serbia.

    abstract:BACKGROUND/AIM:Children and adolescents who enter a child welfare system are at higher risk of suffering from mental disorders, physical health, and/or social and educational problems than the general population of the same age is. This study was organized with the aim to evaluate the general characteristics of quality...

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    doi:

    authors: Damnjanović M,Lakić A,Stevanović D,Jovanović A,Jancić J,Jovanović M,Leposavić L

    更新日期:2012-06-01 00:00:00

  • [Assesment of lower extremities ischemic disease by thallium 201 perfusion scintigraphy in patients with diabetic angiopathy].

    abstract:BACKGROUND/AIM:Tibial perfusion in diabetic microangiopathy is considered to be a diagnostic problem. A special place in quantifying muscle microcirculatory perfusion belongs to thallium 201 muscle perfusion scintigraphy (201T1 PS). Thallium, showing the characteristics of potassium (K+), enters a cell by means of acti...

    journal_title:Vojnosanitetski pregled

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    authors: Cizmić M,Pucar D,Zoranović U

    更新日期:2011-02-01 00:00:00

  • [Autologous spongious iliac bone graft in the treatment of ununited diaphyseal fractures of the long bones].

    abstract::In the treatment of ununited diaphyseal fractures the authors stick to three basic principles: rigid fragment stabilization, reduced fracture split and osteogenous stimulus addition. A multiple autologous spongious iliac bone graft was used as an ostogenous stimulus. This method was applied in 47 patients within the p...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Jovanović Z,Popović Z,Mircić M

    更新日期:1989-05-01 00:00:00

  • Intrathecal synthesis of complement components C3c and C4 in the central nervous system infections with signs of the acute serous meningitis syndrome.

    abstract::Two hundred and ten patients with meningismus and the infections of the central nervous system (CNS) with the clinical symptoms and signs of the acute serous meningitis syndrome, were divided in to groups according to etiology (enterovirus meningitis-ENTERO, serous meningitis various etiology-SM and tuberculous mening...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0203265t

    authors: Tatomirović Z,Bokun R,Bokonjić D

    更新日期:2002-05-01 00:00:00

  • [Complications and mortality in surgery of cerebral aneurysms].

    abstract:AIM:To establish the risk factors for complications and fatal outcome after the operative occlusion of cerebral aneurysms. METHODS:Retrospective study on 91 (lethality rate) and on 72 operated patients (complications). For survived and dead patients, as well as for patients with and without complications, following pa...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0204355r

    authors: Roganović Z,Pavlićević G

    更新日期:2002-07-01 00:00:00

  • [Morpho-etiologic problems of pseudomembranous lesions of the colon].

    abstract::Pseudomembranous colitis (PMC) is an infectious colon disease caused by Cl. difficile toxin. Each change of the intraluminal microbiological balance as well as damages of the hemato-enteral barrier may cause changes in the enteral flora and selective proliferation of anaerobic bacterial strains. PMC has been most freq...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Simić M,Tasić M

    更新日期:1989-03-01 00:00:00

  • [Stability of B1 and G2 aflatoxins after routine water chlorination].

    abstract::Stability of aflatoxin B1 and G2 as water pollutants in the presence of active chlorine was examined. One liter of demineralized water was polluted with 0.5 mg of aflatoxin B1 and with 0.5 mg of aflatoxin G2. Routine chlorination with Pantacide tablets was applied afterwards. Initial aflatoxin concentrations and those...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Radosević P

    更新日期:1990-07-01 00:00:00

  • [Antibiotic resistance in hospital strains of Enterococcus faecalis and Enterococcus faecium].

    abstract::The aim of this study was to determine the resistance of Enterococcus faecalis (E. faecalis) and Enterococcus faecium (E. faecium) to penicillin, ampicillin, vancomycin, teicoplanin, gentamicin (high level), streptomycin (high level), oxytetracycline, chloramphenicol, rifampin, erythromycin, ciprofloxacin, norfloxacin...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0205499m

    authors: Mirović V

    更新日期:2002-09-01 00:00:00

  • Histological characteristics and markers of proliferation and differentiation in rat brain with experimental glioma.

    abstract:BACKGROUND/AIM:The cell line C6 is a continuous cell line of rat glioma and, as a transplantable line, is frequently used for induction into in vivo model of primary brain tumor. It is believed that, pursuant to its histological traits and biological behavior, this experimental tumor corresponds to human anaplastic ast...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Ristić S,Mirić M,Jović S,Ristić S,Karić J

    更新日期:2014-09-01 00:00:00

  • [Success rate of intrauterine insemination in patients with unknown infertility].

    abstract:BACKGROUND/AIM:Unknown cause of infertility exists in 10%-26% of couples with infertility problems. Treatment of these couples depends on the posibility of correcting the unidentified defect over time. Intrauterine insemination (IUI) and ovaluation stimulation are methods of choice in treatment of unexplained fertility...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1204301j

    authors: Jasović V,Jasović-Siveska E

    更新日期:2012-04-01 00:00:00

  • Sex differences in anatomical parameters of acetabulum among asymptomatic Serbian population.

    abstract:BACKGROUND/AIM:Anatomical parameters of the bony components of the hip joint are essential for better understanding of etiopathogenesis of diseases like primary osteoarthrosis of the hip joint. The aim of this reserch was to examine the normal acetabular morphometry in Serbian population and to determine whether there ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Jeremić D,Macuzić IZ,Vulović M

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  • Right ventricular myxoma - a case report.

    abstract:INTRODUCTION:Myxomas arising from the right ventricle are extremely rare. CASE REPORT:We presented a 71-year-old patient with worsening symptoms of the exertional dyspnea and atypical chest pains lasting 6 months. A transthoracic and transesophageal echocardiogram revealed a large, 2.6 x 2.2 cm, ovoid, well-circumscri...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1306609o

    authors: Obrenović-Kirćanski B,Mikić A,Velinović M,Bozić V,Kovacević-Kostić N,Karan R,Parapid B,Djukić P,Savić D,Vranes M

    更新日期:2013-06-01 00:00:00

  • [Vaccination against hepatitis B in the Sarajevo Military Hospital].

    abstract::The intermediate prevalence of HBV infection (28.6%) was found in the staff of the Sarajevo Military Hospital without any significant difference related to the profession of the examinees. The vaccination against hepatitis B was accepted by 23 (18.3%) of 126 candidates and it was performed with 3 doses of "ENGERIX-B" ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Ler Z

    更新日期:1991-05-01 00:00:00

  • [Initial masseter muscle fatigue in maximal voluntary teeth clenching].

    abstract::Fatigue of striated muscles is defined as the impossibility to generate the expected or required force during the repeated contraction. During the maximal voluntary teeth contraction in the position of central occlusion the initial fatigue in masticatory muscles during the isometric contraction occurs. If a person can...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0201043m

    authors: Miljković H,Zeljković M,Anojcić M

    更新日期:2002-01-01 00:00:00

  • Patients' expectation and satisfaction with complete denture before and after the therapy.

    abstract:BACKGROUND/AIM:Difficulties in the acceptance of dentures are multifactorial including psychosocial ones. It is questionable whether the patients' satisfaction depends only on the complete denture therapy characteristics. The aim of the study was to evaluated patients' expectation and satisfaction with complete denture...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp140229002z

    authors: Zou Y,Zhan D

    更新日期:2015-06-01 00:00:00

  • Dystocia as a cause of untimely cesarean section.

    abstract:BACKGROUND/AIM:One of the most frequent indications for cesarean section is dystocia. It is impossible to predict, difficult to identify and coincident with the rapid expiry of the expected time, so it is important to point out some mistakes in expecting vaginal delivery. The aim of this study was to examine the freque...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Djurić J,Arsenijević S,Banković D,Protrka Z,Sorak M,Dimitrijević A,Tanasković I

    更新日期:2012-07-01 00:00:00

  • [Working environment conditions and occupational disorders in artillery unit personnel].

    abstract::Occupational environment risk factors and health status of 172 soldiers and 89 officers were examined aiming to discover early signs of occupational diseases and disorders in artillery personnel. Among all physical and chemical risk factors noise caused by artillery and infantry firing (140 to over 170 dB) were the mo...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Petrović D,Hadzibegović E,Radojković Z,Kitanovski B,Fiser A,Hrnjak M,Misović M

    更新日期:1990-07-01 00:00:00

  • [Quality of life assessment in patients with multiple sclerosis].

    abstract:BACKGROUND/AIM:Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system. The main physiopatological feature of MS is demyelination. Multiple sclerosis is one of three most common causes of severe disability in youngest people. In patients with MS, apart from complete psychophysical status and...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0908645k

    authors: Tepavcević DK,Pekmezović T,Drulović J

    更新日期:2009-08-01 00:00:00

  • Preoperative echocardiographic parameters influencing quality of life five years after coronary artery bypass graft surgery.

    abstract:BACKGROUND/AIM:Factors associated with mortality and morbidity following coronary artery bypass graft surgery have been well defined and the Parsonnet score is widely used in mortality prediction. The evaluation of quality of life has not been still implemented in everyday work and preoperative echocardiographic factor...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0909718z

    authors: Zdravković M,Ristić M,Milić N,Zdravković D,Krotin M,Randjelović T

    更新日期:2009-09-01 00:00:00

  • Antiepileptic, behavioral, and antidepressant effects of adjuvant lamotrigine therapy in drug-resistant epilepsy.

    abstract:AIM:To evaluate the behavioral effects of lamotrigine as add-on therapy in treatment-resistant epilepsy. METHODS:An open, prospective, long-term study of lamotrigine as adjuvant therapy was performed in 56 patients with drug-resistant epilepsy (female/male ratio 35/21, age range 16-51 years). All the patients kept sei...

    journal_title:Vojnosanitetski pregled

    pub_type: 临床试验,杂志文章

    doi:10.2298/vsp0405485m

    authors: Martinović Z,Buder N,Milovanović M,Velićković R

    更新日期:2004-09-01 00:00:00

  • Health care economics in Serbia: current problems and changes.

    abstract::One of the fundamental rights of every human being is to enjoy "the highest attainable standard of health". Achieving better health requires no only adequate medical knowledge and technologies, laws and social measures in the field of health care, but also sufficient funding for fulfilling people's right to health. Ho...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp120205002s

    authors: Stosić S,Karanović N

    更新日期:2014-11-01 00:00:00

  • [The long-term remission of rheumatoid arthritis with a single cycle of rituximab].

    abstract:INTRODUCTION:Rituximab selectively targets CD20+ B cells and presumably protects joints in rheumatoid arthritis. Complete remissions after a single treatment with rituximab, in some cases for longer than 1 year, are observed in only the minority of patients. We reported a patient suffering from refractory rheumatoid ar...

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    doi:10.2298/vsp1201078g

    authors: Glisić B,Knezević B

    更新日期:2012-01-01 00:00:00

  • Genetic alterations in B-cell non-Hodgkin's lymphoma.

    abstract:BACKGROUND:Although the patients with diagnosed B-NHL are classified into the same disease stage on the basis of clinical, histopathological, and immunological parameters, they respond significantly different to the applied treatment. This points out the possibility that within the same group of lymphoma there are diff...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0502087m

    authors: Magić Z,Novković T,Cikota B,Tasić-Radić O,Tarabar O,Stamatović D

    更新日期:2005-02-01 00:00:00

  • [Antibiotic prophylaxis in elective colorectal surgery].

    abstract::The prospective clinical examination of 80 patients with the verified carcinoma of the colon and rectum was performed at the Clinic of General and Vascular Surgery of the M.M.A. in the period 1989-1990 with the aim to evaluate efficacy and justified use of antibiotic prophylaxis or prophylaxis and antibiotic therapy a...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Jevtić M,Petrović M,Stanković N

    更新日期:1993-05-01 00:00:00

  • Relationship of adipokine to insulin sensitivity and glycemic regulation in obese women--the effect of body weight reduction by caloric restriction.

    abstract:BACKGROUND/AIM:Visceral fat is highly active metabolic and endocrine tissue which secretes many adipokines that act both on local and systemic level. It is believed that adipokines and "low-grade inflammatory state" represent a potential link between obesity, metabolic syndrome, insulin resistance and cardiovascular di...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1303284v

    authors: Golubović MV,Dimić D,Antić S,Radenković S,Djindjić B,Jovanović M

    更新日期:2013-03-01 00:00:00

  • [Post-voiding residual urine and capacity increase in orthotopic urinary diversion--standard vs. modified technique].

    abstract:BACKGROUND/AIM:Ever since the time when the first orthotopic urinary diversion (pouch) was performed there has been a constant improvement and modification of surgical techniques. The aim has been to create a urinary reservoir similar to normal bladder, to decrease incidence of postoperative complications and provide a...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1007558b

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  • [Significance of heterogenity in endothelium-dependent vasodilatation occurrence in healthy individuals with or without coronary risk factors].

    abstract:BACKGROUND/AIM:Brachial artery flow-mediated dilation (FMD) is extensively used for non-invasive assessment of endothelial function. Traditionally, FMD is calculated as a percent change of arterial diameter from the baseline value at an arbitrary time point after cuff deflation (usually 60 seconds). Considerable indivi...

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    doi:10.2298/vsp0910813p

    authors: Polovina M,Potpara T,Giga V,Ostojić M

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  • Rare locations of metastastatic renal cell carcinoma: a presentation of three cases.

    abstract:INTRODUCTION:Metastatic renal cell carcinoma (RCC) frequently spreads not only to neighboring lymph nodes, but also to distant organs, including the lungs, liver, bones and brain. CASE REPORT:We presented three cases of RCC with colon metastasis. In the first, 63-year-old patient, after left nephrectomy followed with ...

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    pub_type: 杂志文章

    doi:10.2298/vsp120515014m

    authors: Milović N,Lazić M,Aleksić P,Radovanović D,Bancević V,Savić S,Stamenković D,Spasić D,Kosević B,Perović D,Jovanović M

    更新日期:2013-09-01 00:00:00