Abstract：
:Several laboratories have developed culture systems that allow the generation of large numbers of human dendritic cells (DC) from monocytes using granulocyte-macrophage colony stimulating factor (GM-CSF), and interleukin-4 (IL-4). In this work we provided evidence that GM-CSF (100 ng/ml) in combination with a low concentration of IL-4 (5 ng/ml) was efficient in the generation of immature, non-adherent, monocyte-derived DC as the same concentration of GM-CSF, and ten times higher concentration of IL-4 (50 ng/ml). This conclusion was based on the similar phenotype profile of DC, such as the expression of CD1a, CD80, CD86, and HLA-DR, down-regulation of CD14, and the absence of CD83, as well as on their similar allostimulatory activity for T cells. A higher number of cells remained adherent in cultures with lower concentrations of IL-4 than in cultures with higher concentrations of the cytokine. However, most of these adherent cells down-regulated CD14 and stimulated the proliferation of alloreactive T cells. In contrast, adherent cells cultivated with GM-CSF alone were predominantly macrophages, as judged by the expression of CD14 and the inefficiency to stimulate alloreactive T cells. DC generated in the presence of lower concentrations of IL-4 had higher proapoptotic potential for the Jurkat cell line than DC differentiated with higher concentrations of IL-4, suggesting their stronger cytotoxic, anti-tumor effect.
journal_name
Vojnosanit Pregljournal_title
Vojnosanitetski pregledauthors
Colić M,Jandrić D,Stojić-Vukanić Z,Antić-Stanković J,Popović P,Vasilijić S,Milosavljević P,Balint Bdoi
10.2298/vsp0305531csubject
Has Abstractpub_date
2003-09-01 00:00:00pages
531-8issue
5eissn
0042-8450issn
2406-0720journal_volume
60pub_type
杂志文章abstract：BACKGROUND/AIM:The modification of implant surfaces could affect mechanical implant stability as well as dynamics and quality of peri-implant bone healing. The aim of this 3-month experimental study in dogs was to investigate implant stability, marginal bone levels and bone tissue response to zirconia dental implants w...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp121003034d
更新日期：2014-05-01 00:00:00
abstract：:The study comprised 25 patients with masked depression and 30 patients with endogenous depression. According to the general characteristics both groups were homogenous and accordingly, comparable. Together with clinical evaluation of depressive syndrome, psychological management was applied. Rorschach test, Thematic A...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Occurrence of methicillin resistant staphylococcal strains in hospital environment is more frequently found. These strains are multiresistant so that diseases caused by them require a special therapeutical approach. They are significant causative agents of intrahospital infections which may have epidemic character. Us...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：BACKGROUND/AIM:Congenital absence of vagina is known from ancient times of Greek. According to the literature data, incidence is 1/4 000 to 1/20 000. Treatment of this anomaly includes non-operative and operative procedures. McIndoe procedure uses split skin graft by Thiersch. The aim of this study was to establish ana...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0902107k
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND/AIM:Cerebrovascular diseases are the third leading cause of mortality in the world, following malignant and cardiovascular diseases. Therefore, their timely and precise diagnostics is of great importance. The aim of this study was to compare duplex scan Color Doppler ultrasonography (CDU) with multislice com...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章,随机对照试验
doi：10.2298/vsp1105423v
更新日期：2011-05-01 00:00:00
abstract：Background/Aim:The overuse of antibiotics unnecessarily exposes patients to risk of side effects, encourages reconsultation for similar problems and enhances antimicrobial resistance. The use of antibiotics in the year 2011 in Montenegro was high (39.05 Defined Daily Dose – DDD/1,000 inhabitants/day), but it was not co...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/VSP150626146S
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:[corrected] Descending necrotizing mediastinitis (DNM) is an acute, serious, septic disease which results from a complication of oropharyngeal infection. The disease requires a prompt diagnosis and radical surgical treatment to reduce high mortality (40%). The optimal form of mediastinal drainage remains con...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0607677c
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND/AIM:Thanatophobia is an exaggerated, specific, structured fear of death. It appears in childhood and continues to grow over the years, and in the old age it is accompanied with nosophobia and other mental disorders. The aim of this study was to analyze thanatophobia in dialysed patients which was in the dire...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0604397n
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:Atrial fibrillation is the most frequent cardiac dysrhythmia. The aim of this study was to show the role and the efficacy of a dual chamber pacemaker with the algorithm of atrial dynamic overdrive, in the suppression of paroxysmal atrial fibrillation. CASE REPORT:A woman with a classical bradycardia-tachyca...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0504329r
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND/AIM:Urinary tract infections are still the most frequent complications in patients with spinal cord injury (SCI). The aim of this study was to analyze the factors influencing development of urinary tract infections during rehabilitation in patients with SCI. METHODS:This retrospective case/control study inc...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp140725116s
更新日期：2015-12-01 00:00:00
abstract：:The investigation was performed on a sample of members of a special parachute unit, aged 25-30 years. During combat activities in the territory of former Yugoslavia, in the period of 1991-92, they were exposed to intensive stress and psychotraumatic events which could have detrimental influence on personality and psyc...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：BACKGROUND:Acquired elevation of the diaphragm is mostly the result of phrenic nerve paralysis, some of thoracic and abdominal patological states, and also some of neuromuscular diseases. Surgical treatment is rarely performed and is indicated when lung compression produces disabilitating dyspnea, and includes plicatio...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0704279c
更新日期：2007-04-01 00:00:00
abstract：INTRODUCTION:Sinus pericranii is a rare vascular anomaly. It is characterized by abnormal communication between the extracranial and intracranial venous system, usually involving the superior sagittal sinus and occasionally the transverse sinus. Off the midline lesions are extremely rare. Multiplicity, associated venou...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp140416065i
更新日期：2015-09-01 00:00:00
abstract：:War injuries of colon and rectum are real challenge for war surgeons. The aim of the study was to point out the necessity of war surgical doctrine application, considering the risk factors in the choice of primary surgical procedure and surgeon's experience in managing this kind of injuries. Postoperative complication...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：BACKGROUND/AIM:Primary open-angle glaucoma is a multifactorial and progressive neuropathy, characterised by the acquired loss of ganglion cells of the retina and their axons. One of the risk factors for primary open-angle glaucoma is myopia over 5 diopters (D). The aim of our work was to investigate two groups of patie...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp111229024g
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND/AIM:Interest in dental esthetics has increased rapidly during the last few decades among both patients and dentists, and the creation of a natural dental appearance has become an important task in all fields of dentistry, especially in prosthodontics and restorative dentistry. The aim of this research was to...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND/AIM:Identification of patients with arterial hypertension and a possible onset of heart failure by determining the concentration of N-terminal pro-B-type natriuretic peptide (NT-proBNP) enables timely intensification of treatment and allows clinicians to prescribe and implement optimal and appropriate care. ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp110322048p
更新日期：2013-08-01 00:00:00
abstract：:Chemical induction of hepatocyte transformation induced by dimethylaminoazobenzene (DAB) effect has been followed up in the initial phases of this process. Of great importance has been early recognition of primary cell population, i.e. early detection of chemical carcinogenic effects. ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：INTRODUCTION:Sinus histiocytosis with massive lymphadenopathy is a rare benign self-limiting disease of unknown etiology. The salivary gland involvement, indicating the extranodal character of the disease, often presents a diagnostic dilemma requiring immunohistochemical staining of surgically removed tumor to confirm ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp1408780p
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND/AIM:Decreasing of arterial flow below the critical level leads to capillary endothelium edema and to further worsening of tissue perfusion. Hypertonic solution infusion provides mild and short plasma osmolality increasing, while colloidal solutions intensify that effect. The aim of this study was to investig...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章,随机对照试验
doi：10.2298/vsp0710685s
更新日期：2007-10-01 00:00:00
abstract：BACKGROUND/AIM:The differential diagnosis of fever of unknown origin (FUO) includes more than 200 different diseases and conditions. The aim of this study was to identify the most frequent causes of FUO among adult patients according to gender and age. METHODS:The study included 74 patients examined from June 2010 to ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp140820128p
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND/AIM:The task of a forensic examiner during exhumation of skeletal remains is to calculate antemortem height of a person whose skeletal remains were found. Anthropological investigations which provided formulae for calculating ante-mortem body height date back from XIX or from the first half of XX centuries. ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp1205394m
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND/AIM:Multifocal motor neuropathy (MMN) is an immune-mediated disorder characterised by slowly progressive asymetrical weakness of limbs without sensory loss. The objective of this study was to investigate the involvement of brachial plexus using combined cervical magnetic stimulation and magnetic resonance im...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp1408723b
更新日期：2014-08-01 00:00:00
abstract：Background/Aim:Sametimes war veterans may resort to such strategies as preducing exaggerated symptoms and malingerating in order to obtain material compensation rights. The aim of this study was to assess the accuracy of the diagnosis of posttraumatic stress disorder (PTSD) on the basis of which war veterans were entit...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/VSP150124090S
更新日期：2016-10-01 00:00:00
abstract：:The values of vital capacity (VC), forced expiratory volume in the first second (FEV1) and Tiffeneau index (100xFEV1/VC) were determined in 14,234 examinees in the period 1977-1987. Examinations were performed using the Godart expirometer. After the statistical analysis of the results being performed, the unique table...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：INTRODUCTION:Myxomas arising from the right ventricle are extremely rare. CASE REPORT:We presented a 71-year-old patient with worsening symptoms of the exertional dyspnea and atypical chest pains lasting 6 months. A transthoracic and transesophageal echocardiogram revealed a large, 2.6 x 2.2 cm, ovoid, well-circumscri...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp1306609o
更新日期：2013-06-01 00:00:00
abstract：:Occupational environment risk factors and health status of 172 soldiers and 89 officers were examined aiming to discover early signs of occupational diseases and disorders in artillery personnel. Among all physical and chemical risk factors noise caused by artillery and infantry firing (140 to over 170 dB) were the mo...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：BACKGROUND/AIM:Brachial artery flow-mediated dilation (FMD) is extensively used for non-invasive assessment of endothelial function. Traditionally, FMD is calculated as a percent change of arterial diameter from the baseline value at an arbitrary time point after cuff deflation (usually 60 seconds). Considerable indivi...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0910813p
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND/AIM:Nocturia often occures in patients with benign prostata hyperplasia (BPH). The aim of the study was to investigate the frequency of nocturia in patients with BPH. Nocturia and other factors associated with it were also investigated. METHODS:Forty patients with the confirmed diagnosis of BPH were studied...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0810751l
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND/AIM:Feasibility of radical prostatectomy (RP) in patients with locally invasive prostate cancer (PC) is assessed by the standard parameters such as the stage of the disease, serum prostate-specific antigen (PSA) and bioptic Gleason grade (GG). Intermediate values of PSA are important in predicting the local ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0708531c
更新日期：2007-08-01 00:00:00
