[The long-term remission of rheumatoid arthritis with a single cycle of rituximab].

Abstract:

INTRODUCTION:Rituximab selectively targets CD20+ B cells and presumably protects joints in rheumatoid arthritis. Complete remissions after a single treatment with rituximab, in some cases for longer than 1 year, are observed in only the minority of patients. We reported a patient suffering from refractory rheumatoid arthritis who responded to rituximab with sustained remission. CASE REPORT:A 78-year-old woman was diagnosed with seropositive rheumatoid arthritis in 2001. The disease remained active despite conventional disease modifying drugs. In February 2007 the disease was highly active. Two infusions of rituximab 1 000 mg on days 1 and 15 were performed. Concomitant treatment consisted of metotrexate 10 mg/week and prednisolone 5 mg/day. The patients were assessed every month after receiving rituximab. Remission was achieved three months later. The patient was retreated with a second cycle of rituximab in December 2009 due to arthritic flare. CONCLUSION:This case report showed that the rituximab treatment was feasible and led to a clinically relevant and long lasting improvement in disease activity.

journal_name

Vojnosanit Pregl

journal_title

Vojnosanitetski pregled

authors

Glisić B,Knezević B

doi

10.2298/vsp1201078g

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

78-80

issue

1

eissn

0042-8450

issn

2406-0720

journal_volume

69

pub_type

杂志文章
  • [Adaptation problems of soldiers to the military environment].

    abstract::Sixty six conscripts were examined during the first 30 days of military service, in the period of adaptation to the military environment. Out of total number of the examined soldiers, 83.33% of them enlisted with previous problems from the civilian life. Two thirds of the examined soldiers experience difficulties endu...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Dedić G,Krstić J

    更新日期:1996-01-01 00:00:00

  • Caregivers’ attitudes, knowledge and practices of oral care at nursing homes in Serbia.

    abstract:Background/Aim:Within the elderly population, residents in nursing homes, there is a greather risk of caries, periodontal disease and teeth loss. Assistance of caregivers in maintaininig good oral hygiene besides improving oral health can improve of residents general health and the qulity of their lives. The aim of thi...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/VSP141001065S

    authors: Stančić I,Petrović M,Popovac A,Vasović M,Despotović N

    更新日期:2016-07-01 00:00:00

  • [Carbon dioxide inhibits the generation of active forms of oxygen in human and animal cells and the significance of the phenomenon in biology and medicine].

    abstract::Carbon dioxide (CO2) influence in generation of active oxygen forms (AOF) in human mononuclear cells (blood phagocytes and alveolar macrophages) and animal cells (tissue phagocytes, parenchymal and interstitial cells of liver, kidney, lung, brain and stomach) was investigated. The AOF generation was examined by the me...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Boljevic S,Kogan AH,Gracev SV,Jelisejeva SV,Daniljak IG

    更新日期:1996-07-01 00:00:00

  • [Manufacture of tetracaine hydrochloride tablets using direct compression and moist granulation].

    abstract::The results of quality testing of lozenges made by direct compression and by wet granulation procedure (Ph. Jug. IV) are presented. The aim was to determine hardness, friability and disintegration of the lozenges. Considering the fact that the produced tetracaine hydrochloride lozenges were not transported, but were m...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Gazikalović E,Obrenović D,Nidzović Z,Colić O

    更新日期:2002-11-01 00:00:00

  • [Reduction of juvenile obesity by programmed physical exercise and controlled diet].

    abstract:BACKGROUND/AIM:Obesity is the most common disease of nutrition and is the consequence of reduced movement. Unfortunately, this problem is increasingly present in juvenile age, so that the pediatric outpatient offices are dominated by obese young people. The aim of this study was to evaluate and quantify the effects of ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1201009s

    authors: Sente J,Jakonić D,Smajić M,Mihajlović I,Vasić G,Romanov R,Marić L

    更新日期:2012-01-01 00:00:00

  • [Oxidative status evaluation in elite karate athletes during training process].

    abstract:BACKGROUND/AIM:Oxidative stress is a state of disturbed balance between reactive oxygen species (ROS) and reactive nitrogen species (RNS) on the one hand, and antioxidative defense on the other. As a result of oxidative stress we have irreversible changes in cell function leading to pathological tissue changes, develop...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0907551p

    authors: Pesić S,Jakovljević V,Cubrilo D,Zivković V,Jorga V,Mujović V,Stojimirović B

    更新日期:2009-07-01 00:00:00

  • [Descending necrotizing mediastinitis].

    abstract:BACKGROUND:[corrected] Descending necrotizing mediastinitis (DNM) is an acute, serious, septic disease which results from a complication of oropharyngeal infection. The disease requires a prompt diagnosis and radical surgical treatment to reduce high mortality (40%). The optimal form of mediastinal drainage remains con...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0607677c

    authors: Cvijanović V,Stanić V,Ristanović A,Gulić B,Durković S,Stamenović D,Marić N

    更新日期:2006-07-01 00:00:00

  • [Antibiotic resistance in hospital strains of Enterococcus faecalis and Enterococcus faecium].

    abstract::The aim of this study was to determine the resistance of Enterococcus faecalis (E. faecalis) and Enterococcus faecium (E. faecium) to penicillin, ampicillin, vancomycin, teicoplanin, gentamicin (high level), streptomycin (high level), oxytetracycline, chloramphenicol, rifampin, erythromycin, ciprofloxacin, norfloxacin...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0205499m

    authors: Mirović V

    更新日期:2002-09-01 00:00:00

  • [Diagnosis and results of treatment of heart myxoma].

    abstract:BACKGROUND/AIM:Myxoma is the most common benign primary cardiac neoplasm, and usually originates from the left atrial septum. Early diagnosis of cardiac myxomas depends on a high index of a clinical suspicion. Surgical management must be done as soon as possible after diagnosis. The aim of this retrospective study was ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1110851r

    authors: Rafajlovski S,Ilić R,Gligić B,Kanjuh V,Tatić V,Ristić A,Obradović S,Matunović R,Prcović B

    更新日期:2011-10-01 00:00:00

  • [Post-voiding residual urine and capacity increase in orthotopic urinary diversion--standard vs. modified technique].

    abstract:BACKGROUND/AIM:Ever since the time when the first orthotopic urinary diversion (pouch) was performed there has been a constant improvement and modification of surgical techniques. The aim has been to create a urinary reservoir similar to normal bladder, to decrease incidence of postoperative complications and provide a...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1007558b

    authors: Bancević V,Aleksić P,Milović N,Kosević B,Campara Z,Stamenković D

    更新日期:2010-07-01 00:00:00

  • [Endoscopic balloon dilatation of achalasia under fluoroscopic guidance].

    abstract::In 41 patients, aged 17-81 years, with confirmed achalasia, endoscopic balloon-dilatation was performed under fluoroscopic control. Favorable results were achieved in 39 patients--in 36 patients balloon dilatation was successful after the first intervention, and in the other 3 patients dilatation had to be repeated tw...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Lukić-Kostić L,Lukacević S,Petković G

    更新日期:1999-01-01 00:00:00

  • [Total intravenous anesthesia with propofol with midazolam coinduction--the anesthesia of choice in cataract surgery].

    abstract::Comparative clinical investigation was performed in 80 ASA I/II patients undergoing cataract surgery on one eye. Patients were randomly divided in to four groups, according to the method of anesthesia. Intraoperatively (T0-T6), decreasing of intraocular pressure (IOP) to the optimal values at the start of the operatio...

    journal_title:Vojnosanitetski pregled

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Romić P

    更新日期:2000-03-01 00:00:00

  • [Frequency and risk factors of the use of psychoactive substances among the young].

    abstract:BACKGROUND/AIM:Socio-economic changes that occured in the wake of dismemberment of former Yugoslavia resulted in the appearance of social pathology, one of which was the increase in the use of psychoactive substances. The overwhole epidemiological research in the use of psychoactive substances has not been conducted so...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0806441p

    authors: Pavlović Z,Jakovljević B

    更新日期:2008-06-01 00:00:00

  • [Predictive significance of residual ischemia detected by the dobutamine stress-echocardiography test soon after the first uncomplicated myocardial infarction].

    abstract:BACKGROUND:To evaluate the long-term prognostic value of dobutamine stress-echocardiography (ECG) test for new coronary events (new episodes of angina pectoris, cardiac-related deaths, and reinfarctions) early after the first uncomplicated myocardial infarction. METHODS:Dobutamine stress-echocardiography tests were pe...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0402155k

    authors: Karanović N,Todorović L,Perisić Z,Pavlović M

    更新日期:2004-03-01 00:00:00

  • [Outcome of kidney transplantation in patients on peritoneal dialysis].

    abstract::The initial experience suggested that kidney transplantation could be hazardous for patients on peritoneal dialysis due to the high risk of peritonitis and a possible high incidence of acute rejection. In this paper we have presented our experience with kidney transplantation in these patients. During the last four ye...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Hrvacevic R,Maksic Dj,Aleksic S,Paunic Z,Ignjatovic Lj,Vavic N,Draskovic-Pavlovic B,Maric M

    更新日期:2001-09-01 00:00:00

  • [Microscopic polyangiitis].

    abstract::Microscopic polyangiitis is a very rare disease characterized by the lesions of arteriolae, venulae and capillaries--mainly of the kidneys and lungs, but also of other systems and organs. The elevated titer of anti-myeloperoxidase ANCA is very important immunological indicator. The main changes in our patient were rel...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Rabrenovic V,Kovacevic Z,Jovanovic D,Rabrenovic M,Dimitrijevic J,Skataric V,Popovic D,Abugras S

    更新日期:2001-05-01 00:00:00

  • Quality-of life of the elderly in urban and rural areas in Serbia.

    abstract:BACKGROUND/AIM:The number of elderly people in the world is growing, in Serbia as well. Serbia is already among the top ten countries with the oldest population, it is the fact. Aging influences the quality of life in different ways. The aim of this study was to assess the health-related quality of life of the elderly ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp140831107u

    authors: Urosević J,Odović G,Rapaić D,Davidović M,Trgovcević S,Milovanović V

    更新日期:2015-11-01 00:00:00

  • Idionathic retroneritoneal fibrosis: A Report on 15 Patients.

    abstract:BACKGROUND/AIM:Retroperitoneal fibrosis (RPF) repre sents a chronic pathological process characterized by fibro sis which entraps and compresses the ureters and the grea blood vessels in the retroperitoneal space. A specific form of RPF is idiopathic RPF, an uncommon collagen vasculaj disease of unclear etiology. The s...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp140426076h

    authors: Hadzi-Djokić J,Pejčić T,Bašić D,Vukomanović I,Dzamić Z,Aćimović M,Radovanović M

    更新日期:2015-10-01 00:00:00

  • [Masked depression].

    abstract::The study comprised 25 patients with masked depression and 30 patients with endogenous depression. According to the general characteristics both groups were homogenous and accordingly, comparable. Together with clinical evaluation of depressive syndrome, psychological management was applied. Rorschach test, Thematic A...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Preradović M,Griva D,Eror S

    更新日期:1991-01-01 00:00:00

  • [Analysis of intracranial aneurysms from autopsy material].

    abstract::The analysis of 44 intracranial aneurysms found at 7.687 autopsies is performed. The largest number of aneurysms was of congenital (secular) type, then, of arteriosclerotic type while inflammatory and traumatic aneurysms were very rare. The elastic and reticular fibres in the aneurysmal wall and the normal arteries of...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Prodanova I,Tatić V,Milenković D,Radojković M

    更新日期:1992-09-01 00:00:00

  • [Ultrastructural changes in the hepatocytes in rats with dimethylaminoazobenzene poisoning].

    abstract::Chemical induction of hepatocyte transformation induced by dimethylaminoazobenzene (DAB) effect has been followed up in the initial phases of this process. Of great importance has been early recognition of primary cell population, i.e. early detection of chemical carcinogenic effects. ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Skaro-Milić A,Bojanić N

    更新日期:1989-07-01 00:00:00

  • Rare solitary fibrous tumor of the stomach: A case report.

    abstract:INTRODUCTION:Solitary fibrous tumors are rare soft tissue tumors of submesothelial origin and variable malignant potential. The most common localization is pleural, whereas only 0.6% are of extrapleural localization. Solitary fibrous tumor of the peritoneum, especially of gastric serosa is an extremely rare form of thi...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp140131098b

    authors: Bosković T,Zivojinov M,Sabo JI,Budakov Z,Veljković R,Zivojinov S

    更新日期:2015-11-01 00:00:00

  • Right ventricular myxoma - a case report.

    abstract:INTRODUCTION:Myxomas arising from the right ventricle are extremely rare. CASE REPORT:We presented a 71-year-old patient with worsening symptoms of the exertional dyspnea and atypical chest pains lasting 6 months. A transthoracic and transesophageal echocardiogram revealed a large, 2.6 x 2.2 cm, ovoid, well-circumscri...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1306609o

    authors: Obrenović-Kirćanski B,Mikić A,Velinović M,Bozić V,Kovacević-Kostić N,Karan R,Parapid B,Djukić P,Savić D,Vranes M

    更新日期:2013-06-01 00:00:00

  • Asymptomatic flow of Rosai-Dorfman disease.

    abstract:INTRODUCTION:Sinus histiocytosis with massive lymphadenopathy is a rare benign self-limiting disease of unknown etiology. The salivary gland involvement, indicating the extranodal character of the disease, often presents a diagnostic dilemma requiring immunohistochemical staining of surgically removed tumor to confirm ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1408780p

    authors: Petrović D,Mihailović D,Petrović S,Zivković N,Mijović Z,Bjelaković B,Kostić M,Kesić L,Stanković A,Petrović M,Vucković I

    更新日期:2014-08-01 00:00:00

  • [Antibiotic prophylaxis in elective colorectal surgery].

    abstract::The prospective clinical examination of 80 patients with the verified carcinoma of the colon and rectum was performed at the Clinic of General and Vascular Surgery of the M.M.A. in the period 1989-1990 with the aim to evaluate efficacy and justified use of antibiotic prophylaxis or prophylaxis and antibiotic therapy a...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Jevtić M,Petrović M,Stanković N

    更新日期:1993-05-01 00:00:00

  • Bone turnover markers in medicamentous and physiological hyperprolactinemia in female rats.

    abstract:BACKGROUND/AIM:There is a lack of data on the effects of prolactin on calcium metabolism and bone turnover in hyperprolactinemia of various origins. The aim of this study was to compare the influence of medicamentous and physiological hyperprolactinemia on bone turnover in female rats. METHODS:Experimental animals (18...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Radojković D,Pesić M,Ristić T

    更新日期:2014-06-01 00:00:00

  • Vitamin D and parathyroid hormone in relation to bone mineral density in postmenopausal women.

    abstract:BACKGROUND/AIM:Despite vitamin D insufficiency being widely reported, in Serbia the epidemiological data lack information regarding vitamin D status in the sera of postmenopausal women. The aim of this study was to establish the prevalence of inadequate serum 25-hydroxyvitamin D [25(OH)D] concentrations in postmenopaus...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Vuceljić M,Ilić-Stojanović O,Lazović M,Grajić M

    更新日期:2012-03-01 00:00:00

  • [Quality of life assessment in patients with multiple sclerosis].

    abstract:BACKGROUND/AIM:Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system. The main physiopatological feature of MS is demyelination. Multiple sclerosis is one of three most common causes of severe disability in youngest people. In patients with MS, apart from complete psychophysical status and...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0908645k

    authors: Tepavcević DK,Pekmezović T,Drulović J

    更新日期:2009-08-01 00:00:00

  • Quantification of mast cells in different stages of periodontal disease.

    abstract:BACKGROUND/AIM:Mast cells are mononuclear cells originating from bone marrow. They produce various biologically active substances, which allow them to actively participate in immune and inflammatory processes associated with periodontal disease. The study focused on distribution and density of mast cells in healthy gin...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp141222030m

    authors: Marjanović D,Andjelković Z,Brkić Z,Videnović G,Šehalić M,Matvjenko V,Leštarević S,Djordjević N

    更新日期:2016-05-01 00:00:00

  • [Impact of dental implant insertion method on the periimplant epithelial seal--experimental study on dogs].

    abstract:BACKGROUND/AIM:There is a controversial opinion among implantologists on the method of dental implantation that provides more favourable response of soft and bone tissues. The aim of this study was to pathohistologicaly compare the influences of one- and two-phase implant surgical methods on the periimplant epithelial ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1003236m

    authors: Matić S,Stamatović N,Lazić Z,Petković-Curcin A,Bubalo M,Vojvodić D,Djurdjević D

    更新日期:2010-03-01 00:00:00