Abstract:
INTRODUCTION:Rituximab selectively targets CD20+ B cells and presumably protects joints in rheumatoid arthritis. Complete remissions after a single treatment with rituximab, in some cases for longer than 1 year, are observed in only the minority of patients. We reported a patient suffering from refractory rheumatoid arthritis who responded to rituximab with sustained remission. CASE REPORT:A 78-year-old woman was diagnosed with seropositive rheumatoid arthritis in 2001. The disease remained active despite conventional disease modifying drugs. In February 2007 the disease was highly active. Two infusions of rituximab 1 000 mg on days 1 and 15 were performed. Concomitant treatment consisted of metotrexate 10 mg/week and prednisolone 5 mg/day. The patients were assessed every month after receiving rituximab. Remission was achieved three months later. The patient was retreated with a second cycle of rituximab in December 2009 due to arthritic flare. CONCLUSION:This case report showed that the rituximab treatment was feasible and led to a clinically relevant and long lasting improvement in disease activity.
journal_name
Vojnosanit Pregljournal_title
Vojnosanitetski pregledauthors
Glisić B,Knezević Bdoi
10.2298/vsp1201078gsubject
Has Abstractpub_date
2012-01-01 00:00:00pages
78-80issue
1eissn
0042-8450issn
2406-0720journal_volume
69pub_type
杂志文章abstract::Sixty six conscripts were examined during the first 30 days of military service, in the period of adaptation to the military environment. Out of total number of the examined soldiers, 83.33% of them enlisted with previous problems from the civilian life. Two thirds of the examined soldiers experience difficulties endu...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:Background/Aim:Within the elderly population, residents in nursing homes, there is a greather risk of caries, periodontal disease and teeth loss. Assistance of caregivers in maintaininig good oral hygiene besides improving oral health can improve of residents general health and the qulity of their lives. The aim of thi...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/VSP141001065S
更新日期:2016-07-01 00:00:00
abstract::Carbon dioxide (CO2) influence in generation of active oxygen forms (AOF) in human mononuclear cells (blood phagocytes and alveolar macrophages) and animal cells (tissue phagocytes, parenchymal and interstitial cells of liver, kidney, lung, brain and stomach) was investigated. The AOF generation was examined by the me...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract::The results of quality testing of lozenges made by direct compression and by wet granulation procedure (Ph. Jug. IV) are presented. The aim was to determine hardness, friability and disintegration of the lozenges. Considering the fact that the produced tetracaine hydrochloride lozenges were not transported, but were m...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND/AIM:Obesity is the most common disease of nutrition and is the consequence of reduced movement. Unfortunately, this problem is increasingly present in juvenile age, so that the pediatric outpatient offices are dominated by obese young people. The aim of this study was to evaluate and quantify the effects of ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1201009s
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIM:Oxidative stress is a state of disturbed balance between reactive oxygen species (ROS) and reactive nitrogen species (RNS) on the one hand, and antioxidative defense on the other. As a result of oxidative stress we have irreversible changes in cell function leading to pathological tissue changes, develop...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp0907551p
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:[corrected] Descending necrotizing mediastinitis (DNM) is an acute, serious, septic disease which results from a complication of oropharyngeal infection. The disease requires a prompt diagnosis and radical surgical treatment to reduce high mortality (40%). The optimal form of mediastinal drainage remains con...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp0607677c
更新日期:2006-07-01 00:00:00
abstract::The aim of this study was to determine the resistance of Enterococcus faecalis (E. faecalis) and Enterococcus faecium (E. faecium) to penicillin, ampicillin, vancomycin, teicoplanin, gentamicin (high level), streptomycin (high level), oxytetracycline, chloramphenicol, rifampin, erythromycin, ciprofloxacin, norfloxacin...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp0205499m
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND/AIM:Myxoma is the most common benign primary cardiac neoplasm, and usually originates from the left atrial septum. Early diagnosis of cardiac myxomas depends on a high index of a clinical suspicion. Surgical management must be done as soon as possible after diagnosis. The aim of this retrospective study was ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1110851r
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND/AIM:Ever since the time when the first orthotopic urinary diversion (pouch) was performed there has been a constant improvement and modification of surgical techniques. The aim has been to create a urinary reservoir similar to normal bladder, to decrease incidence of postoperative complications and provide a...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1007558b
更新日期:2010-07-01 00:00:00
abstract::In 41 patients, aged 17-81 years, with confirmed achalasia, endoscopic balloon-dilatation was performed under fluoroscopic control. Favorable results were achieved in 39 patients--in 36 patients balloon dilatation was successful after the first intervention, and in the other 3 patients dilatation had to be repeated tw...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Comparative clinical investigation was performed in 80 ASA I/II patients undergoing cataract surgery on one eye. Patients were randomly divided in to four groups, according to the method of anesthesia. Intraoperatively (T0-T6), decreasing of intraocular pressure (IOP) to the optimal values at the start of the operatio...
journal_title:Vojnosanitetski pregled
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND/AIM:Socio-economic changes that occured in the wake of dismemberment of former Yugoslavia resulted in the appearance of social pathology, one of which was the increase in the use of psychoactive substances. The overwhole epidemiological research in the use of psychoactive substances has not been conducted so...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp0806441p
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:To evaluate the long-term prognostic value of dobutamine stress-echocardiography (ECG) test for new coronary events (new episodes of angina pectoris, cardiac-related deaths, and reinfarctions) early after the first uncomplicated myocardial infarction. METHODS:Dobutamine stress-echocardiography tests were pe...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp0402155k
更新日期:2004-03-01 00:00:00
abstract::The initial experience suggested that kidney transplantation could be hazardous for patients on peritoneal dialysis due to the high risk of peritonitis and a possible high incidence of acute rejection. In this paper we have presented our experience with kidney transplantation in these patients. During the last four ye...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract::Microscopic polyangiitis is a very rare disease characterized by the lesions of arteriolae, venulae and capillaries--mainly of the kidneys and lungs, but also of other systems and organs. The elevated titer of anti-myeloperoxidase ANCA is very important immunological indicator. The main changes in our patient were rel...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND/AIM:The number of elderly people in the world is growing, in Serbia as well. Serbia is already among the top ten countries with the oldest population, it is the fact. Aging influences the quality of life in different ways. The aim of this study was to assess the health-related quality of life of the elderly ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp140831107u
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND/AIM:Retroperitoneal fibrosis (RPF) repre sents a chronic pathological process characterized by fibro sis which entraps and compresses the ureters and the grea blood vessels in the retroperitoneal space. A specific form of RPF is idiopathic RPF, an uncommon collagen vasculaj disease of unclear etiology. The s...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp140426076h
更新日期:2015-10-01 00:00:00
abstract::The study comprised 25 patients with masked depression and 30 patients with endogenous depression. According to the general characteristics both groups were homogenous and accordingly, comparable. Together with clinical evaluation of depressive syndrome, psychological management was applied. Rorschach test, Thematic A...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::The analysis of 44 intracranial aneurysms found at 7.687 autopsies is performed. The largest number of aneurysms was of congenital (secular) type, then, of arteriosclerotic type while inflammatory and traumatic aneurysms were very rare. The elastic and reticular fibres in the aneurysmal wall and the normal arteries of...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::Chemical induction of hepatocyte transformation induced by dimethylaminoazobenzene (DAB) effect has been followed up in the initial phases of this process. Of great importance has been early recognition of primary cell population, i.e. early detection of chemical carcinogenic effects. ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract:INTRODUCTION:Solitary fibrous tumors are rare soft tissue tumors of submesothelial origin and variable malignant potential. The most common localization is pleural, whereas only 0.6% are of extrapleural localization. Solitary fibrous tumor of the peritoneum, especially of gastric serosa is an extremely rare form of thi...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp140131098b
更新日期:2015-11-01 00:00:00
abstract:INTRODUCTION:Myxomas arising from the right ventricle are extremely rare. CASE REPORT:We presented a 71-year-old patient with worsening symptoms of the exertional dyspnea and atypical chest pains lasting 6 months. A transthoracic and transesophageal echocardiogram revealed a large, 2.6 x 2.2 cm, ovoid, well-circumscri...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1306609o
更新日期:2013-06-01 00:00:00
abstract:INTRODUCTION:Sinus histiocytosis with massive lymphadenopathy is a rare benign self-limiting disease of unknown etiology. The salivary gland involvement, indicating the extranodal character of the disease, often presents a diagnostic dilemma requiring immunohistochemical staining of surgically removed tumor to confirm ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1408780p
更新日期:2014-08-01 00:00:00
abstract::The prospective clinical examination of 80 patients with the verified carcinoma of the colon and rectum was performed at the Clinic of General and Vascular Surgery of the M.M.A. in the period 1989-1990 with the aim to evaluate efficacy and justified use of antibiotic prophylaxis or prophylaxis and antibiotic therapy a...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND/AIM:There is a lack of data on the effects of prolactin on calcium metabolism and bone turnover in hyperprolactinemia of various origins. The aim of this study was to compare the influence of medicamentous and physiological hyperprolactinemia on bone turnover in female rats. METHODS:Experimental animals (18...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND/AIM:Despite vitamin D insufficiency being widely reported, in Serbia the epidemiological data lack information regarding vitamin D status in the sera of postmenopausal women. The aim of this study was to establish the prevalence of inadequate serum 25-hydroxyvitamin D [25(OH)D] concentrations in postmenopaus...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND/AIM:Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system. The main physiopatological feature of MS is demyelination. Multiple sclerosis is one of three most common causes of severe disability in youngest people. In patients with MS, apart from complete psychophysical status and...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp0908645k
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND/AIM:Mast cells are mononuclear cells originating from bone marrow. They produce various biologically active substances, which allow them to actively participate in immune and inflammatory processes associated with periodontal disease. The study focused on distribution and density of mast cells in healthy gin...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp141222030m
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND/AIM:There is a controversial opinion among implantologists on the method of dental implantation that provides more favourable response of soft and bone tissues. The aim of this study was to pathohistologicaly compare the influences of one- and two-phase implant surgical methods on the periimplant epithelial ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1003236m
更新日期:2010-03-01 00:00:00