Combination total lymphoid irradiation and low-dose corticosteroid therapy for progressive multiple sclerosis.

abstract：INTRODUCTION:Cerebral small vessel disease (SVD) contributes to dementia and disability in the elderly, and may negatively affect stroke outcomes. We aimed to evaluate to what extent single features and global burden of SVD detected with magnetic resonance (MR) are associated with worse outcomes in patients with ischae...

journal_title：Acta neurologica Scandinavica

authors： Arba F,Inzitari D,Ali M,Warach SJ,Luby M,Lees KR,STIR\/VISTA Imaging Collaboration.

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Stimulation of the subthalamic nucleus (STN-DBS) is an established treatment with long-term beneficial effects on motor symptoms in patients with Parkinson's disease (PD). The long-term development of non-motor problems after STN-DBS is not fully understood. In this study, we have studied how non-motor probl...

journal_title：Acta neurologica Scandinavica

authors： Lilleeng B,Gjerstad M,Baardsen R,Dalen I,Larsen JP

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:The aim of this pilot study was to evaluate a psychological therapy program used in the treatment of multiple sclerosis (MS) and including cognitive/behavioral strategies, relaxation training and physical exercise. MATERIAL AND METHODS:The participants were 29 patients with MS recruited from an outpatient u...

journal_title：Acta neurologica Scandinavica

authors： Tesar N,Baumhackl U,Kopp M,Günther V

更新日期：2003-06-01 00:00:00

abstract：:Patients with acute severe headache may have a secondary form of headache. Standard head computer tomography (CT) and cerebrospinal fluid (CSF) examination are often performed in the absence of neurological deficits to exclude subarachnoid hemorrhage (SAH). Increasingly, patients undergo subsequent CT angiography (CTA...

journal_title：Acta neurologica Scandinavica

authors： Alons IM,van den Wijngaard IR,Verheul RJ,Lycklama à Nijeholt G,Wermer MJ,Algra A,Jellema K

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:White matter (WM) integrity of Spinocerebellar ataxia 2 (SCA2) is poorly understood, more so in the early stages of SCA2. In this study, we evaluated the microstructural integrity of the WM tracts with an emphasis on the nature of in vivo pathological involvement in early SCA2. MATERIALS AND METHODS:We evalu...

journal_title：Acta neurologica Scandinavica

authors： Stezin A,Bhardwaj S,Khokhar S,Hegde S,Jain S,Bharath RD,Saini J,Pal PK

更新日期：2020-10-08 00:00:00

abstract：:Amino acid concentrations in plasma of patients with Huntington's disease (HD) were determined in 16 patients and 21 age- and sex-matched healthy controls. Alanine and isoleucine were significantly decreased in HD plasma whereas arginine, histidine, leucine, lysine, ornithine, proline, serine, threonine, tyrosine, and...

journal_title：Acta neurologica Scandinavica

authors： Reilmann R,Rolf LH,Lange HW

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of Rhesus anti-D immunoglobulin (anti-D) in patients with an autoimmune demyelinating neuropathy. MATERIAL AND METHODS:Three patients with an autoimmune mediated neuropathy received 1000 IU anti-D weekly for 2 months. RESULTS:Two patients worsened gradually during the treatment and...

journal_title：Acta neurologica Scandinavica

authors： de Jager AE,Hazenberg CA,van der Hoeven JH

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to investigate myopathic changes in myasthenia gravis (MG) by using turns-amplitude analysis (TAA) and quantitative motor unit potential duration analysis (MUPan), to correlate myopathic changes with severity and duration of the disease and the results of diagnostic tests includin...

journal_title：Acta neurologica Scandinavica

authors： Odabasi Z,Kuruoglu R,Oh SJ

更新日期：2000-05-01 00:00:00

abstract：:Symptoms of acute renal failure were observed in an anorexia patient who had a history of frequent vomiting. The acute renal failure might have resulted from rhabdomyolysis subsequent to a disturbance of electrolyte balance. This acute renal failure might have resulted in death if not treated. We postulate that even a...

journal_title：Acta neurologica Scandinavica

authors： Abe K,Mezaki T,Hirono N,Udaka F,Kameyama M

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:For patients with medication refractory medial temporal lobe epilepsy (MTLE), surgery offers the hope of a cure. However, up to 30% of patients with MTLE continue to experience disabling seizures after surgery. The reasons why some patients do not achieve seizure freedom are poorly understood. A promising the...

journal_title：Acta neurologica Scandinavica

authors： Breedlove J,Nesland T,Vandergrift WA 3rd,Betting LE,Bonilha L

更新日期：2014-08-01 00:00:00

abstract：:The catabolism of orally and subcutaneously administered 14C histamine was studied in myotonic dystrophy patients. No definite abnormalities were observed as for subcutaneously administered histamine. The catabolism of orally administered histamine followed two distinct patterns: In patients with a relatively low endo...

journal_title：Acta neurologica Scandinavica

authors： Sjaastad O,Sjaastad OV

更新日期：1977-11-01 00:00:00

abstract：:Four patients presented with a distinctive syndrome of "numb, clumsy hand" and tactile agnosia. Myelography and computed tomographic myelography (CTM) of the cervical spine documented major spondylotic compressive lesions mainly between the C3 and C5 levels. The cortical responses of dermatomal somatosensory evoked po...

journal_title：Acta neurologica Scandinavica

authors： Chang MH,Liao KK,Cheung SC,Kong KW,Chang SP

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Persons with multiple sclerosis (MS) engage in substantially less overall physical activity than healthy controls, but there is little information on public health rates of physical activity necessary for health benefits. PURPOSE:This study examined the rates of insufficient, moderate, and sufficient physic...

journal_title：Acta neurologica Scandinavica

authors： Motl RW,McAuley E,Sandroff BM,Hubbard EA

更新日期：2015-06-01 00:00:00

abstract：:By a rapid PCR-based method to assess the 8344 mtDNA mutation associated with MERRF disease, we have studied DNA from blood samples of 10 individuals belonging to a family spanning four generations in which one patient showed the complete MERRF phenotype, three other members were less severely affected, while the rema...

journal_title：Acta neurologica Scandinavica

authors： Piccolo G,Focher F,Verri A,Spadari S,Banfi P,Gerosa E,Mazzarello P

更新日期：1993-12-01 00:00:00

abstract：:The urinary excretion of uronic acid and the electrophoretic composition of urinary glucosaminoglycans were studied in 10 members of a family, of which 3 had progressive familial myoclonus epilepsy. This seems to be the first detailed investigation of the excretion of urinary glucosaminoglycans in patients suffering f...

journal_title：Acta neurologica Scandinavica

authors： Poulsen JH

更新日期：1975-09-01 00:00:00

abstract：:Anti-muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) patients show various responses to conventional immunosuppressive treatment and some patients are resistant to these therapies. We report a 50-year-old Japanese man with anti-MuSK antibody-positive MG, who showed no or poor r...

journal_title：Acta neurologica Scandinavica

authors： Shibata-Hamaguchi A,Samuraki M,Furui E,Iwasa K,Yoshikawa H,Hayashi S,Yamada M

更新日期：2007-12-01 00:00:00

abstract：:Adult mice were injected intramuscularly in the region of the vibrissae muscles on the left side of the nose with a small volume of mercuric chloride dissolved in distilled water. The animals were killed after 1-6 weeks and fixed by whole-body perfusion. Frozen sections were taken from different levels of the brain st...

journal_title：Acta neurologica Scandinavica

authors： Arvidson B

更新日期：1990-10-01 00:00:00

abstract：:Eighteen Swedish patients with familial amyloidotic polyneuropathy were tested for the met30 mutation of the transthyretin (TTR) (prealbumin) gene by RFLP analysis of genomic DNA using the restriction enzyme NsiI. The results confirmed previous findings that the Swedish variant of familial polyneuropathy has the same ...

journal_title：Acta neurologica Scandinavica

authors： Holmgren G,Lundgren E,Kangawa K,Kurihara T,Matsukura S,Matsuo H,Nakazato M,Steen L

更新日期：1993-02-01 00:00:00

abstract：:3 patients with the condition of "painful legs and moving toes" are reported. The etiology was unknown in 2 of them, but in 1 patient the symptoms were temporarily relieved by surgery for a lumbar herniated disc. The movements restarted 6 months after surgery. EMG studies showed near rhythmical muscle action potential...

journal_title：Acta neurologica Scandinavica

authors： Wulff CH

更新日期：1982-08-01 00:00:00

abstract：:While the association of spinal cord tumor and high-pressure hydrocephalus is well known, only 5 cases of spinal cord tumor associated with normotensive hydrocephalus have been reported. Two further cases are described here, discussing the possible pathophysiological mechanism. It is suggested that these patients go t...

journal_title：Acta neurologica Scandinavica

authors： Yarnitsky D,Honigman S,Hemli JA,Bental E

更新日期：1987-10-01 00:00:00

abstract：:The risk of stroke related to asymptomatic carotid artery stenosis is known to be increased in high-grade or rapidly progressive stenosis. Information of the prevalence in the general population is required for the recommendation of screening methods to detect patients needing prophylactic treatment. We studied the pr...

journal_title：Acta neurologica Scandinavica

authors： Harer C,Gusev EI

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVES:We studied the in vitro production of variably MS-related cytokines from Sardinian MS and healthy donors bearing the two "Sardinian" MS-associated HLA-DR alleles: DR3 and DR4, with the purpose to evidentiate possible differences in their immune response. MATERIALS AND METHODS:ELISA were used for detection o...

journal_title：Acta neurologica Scandinavica

authors： Sotgiu S,Serra C,Marrosu MG,Dolei A,Pugliatti M,Murgia B,Aiello I,Rosati G

更新日期：1998-11-01 00:00:00

abstract：:Fifteen epileptic patients had their dose of anticonvulsant drugs changed twice, each time by 30-50 per cent of the initial medication. Before the dose change, the patients were given six especially adapted mental performance tests, which were designed to measure vigilance, reaction time and certain aspects of memory....

journal_title：Acta neurologica Scandinavica

authors： Dekaban AS,Lehman EJ

更新日期：1975-10-01 00:00:00

abstract：OBJECTIVES:To describe two patients with progressive external ophthalmoplegia (PEO) and mitochondrial myopathy associated with mutations in mitochondrial DNA, encoding the tRNAAsn gene (MT-TN), which have not previously been published with clinical descriptions. MATERIALS & METHODS:Two unrelated patients with PEO were...

journal_title：Acta neurologica Scandinavica

authors： Visuttijai K,Hedberg-Oldfors C,Lindgren U,Nordström S,Elíasdóttir Ó,Lindberg C,Oldfors A

更新日期：2020-08-31 00:00:00

abstract：:Focal Dystonia (FD) is a chronic neurological disorder, which causes twisting and repetitive movements and abnormal postures induced by involuntary sustained contractions of agonist and antagonist muscles. Based on the hypothesis that several dystonia-related brain regions, including cerebellum, are implicated in ocul...

journal_title：Acta neurologica Scandinavica

authors： Hirsig A,Barbey C,Schüpbach MWM,Bargiotas P

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Treatment with lamotrigine (LTG) during pregnancy is associated with a pronounced risk of seizure deterioration, because pregnancy accelerates LTG elimination. The extent to which pregnancy affects LTG pharmacokinetics is unpredictable and varies considerably among patients. AIM:We propose an algorithm for ...

journal_title：Acta neurologica Scandinavica

authors： Sabers A

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of caudal zona incerta-deep brain stimulation (cZi-DBS) on word-level speech intelligibility in patients with Parkinson's disease, under both an optimal listening condition and a simulated more naturalistic listening condition. MATERIALS AND METHODS:Spoken single words were extract...

journal_title：Acta neurologica Scandinavica

authors： Johansson L,Möller S,Olofsson K,Linder J,Nordh E,Blomstedt P,van Doorn J,Karlsson F

更新日期：2014-07-01 00:00:00

abstract：:We describe a young woman who developed left ventricular failure and pulmonary edema during fulminant onset of multiple sclerosis. One of the numerous plaques was located in the left inferior cerebellar peduncle near the dorsal motor vagal and solitary tract nuclei. Within two days pulmonary edema had cleared, and wit...

journal_title：Acta neurologica Scandinavica

authors： Melin J,Usenius JP,Fogelholm R

更新日期：1996-05-01 00:00:00

abstract：:The present communication is devoted to investigating the possibility that in myotonic dystrophy (MyD) a decreased ATP utilization by the membrane may produce modifications in glycoprotein structure and/or in the supramolecular arrangement of some membrane proteins. The study was carried out a) by determining the memb...

journal_title：Acta neurologica Scandinavica

authors： Sandrini G,Bottiroli G,Nappi G,Balduini C,Brovelli A

更新日期：1982-06-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to describe facial myokymia in experimental animals accompanying kainic acid affects on facial motor neurons. MATERIAL & METHODS:Anesthetized cats were injected with kainic acid into the pons adjacent to the facial nucleus. Facial movements appeared shortly after the inject...

journal_title：Acta neurologica Scandinavica

authors： Zaaroor M,Starr A

更新日期：1997-01-01 00:00:00