[Probiotics as therapeutic agents in irritable bowel syndrome].

Abstract:

:Probiotics are defined as living micro-organisms which, when administered in large amounts, confer a health benefit on the host. The use of probiotics in the therapy of infectious bowel diseases as well as maintaining remission of ulcerative colitis and in pouchitis is evidence-based. Also, in several studies proof could be supplied that specific probiotics relieve the symptoms and the course of irritable bowel syndrome. Some trials showed a significant improvement of irritable bowel syndrome-related constipation via Lactobacillus casei Shirota and E. coli Nissle 1917. Lactobacillus plantarum has been proven effective in reducing pain and abdominal bloating. However, in most of the studies rather small numbers of patients were examined. Furthermore, these studies do not always closely follow scientific standards (randomised, double-blind, placebo-controlled). Therefore, confirmatory studies are necessary to examine the effect of probiotics in irritable bowel syndrome.

journal_name

Z Gastroenterol

authors

Krammer HJ,Schlieger F,Harder H,Franke A,Singer MV

doi

10.1055/s-2004-813934

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

467-71

issue

5

eissn

0044-2771

issn

1439-7803

journal_volume

43

pub_type

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