[The solid pseudopapillary tumor (SPT)--a rare neoplasm of the pancreas].

Abstract:

BACKGROUND:In general, the rare SPT is a tumour of low malignancy predominantly affecting young women. The outcome after radical resection is favourable. In exceptional cases the tumour presents as solid pseudopapillary carcinoma (SPC) with typical malignant features and even metastases. Unresectable liver metastases can be treated with RFA, TACE or chemotherapy. METHODS:We retrospectively reviewed the surgical approach, immunohistochemistry and clinical outcome in five female patients (1998--2007). RESULTS:The mean age was 16 years (range: 13-47 years). For radical tumour removal a pancreato-duodenectomy (n = 3), a distal pancreatectomy (n = 1) and an enucleation (n = 1) were performed. We encountered a mean tumour diameter of 8 cm (range: 6-15 cm), an angioinvasion (3/5) and a lymphatic infiltration (1/5). After 30 to 101 months follow-up four patients were free of recurrence. Chemotherapy has resulted in a survival of over 98 months in a case of SPC with liver metastases. CONCLUSION:SPT is a tumour of low malignancy. Radical resection is recommended for long-term recurrence-free survival. Chemotherapy may prolong survival in SPC with unresectable metastases.

journal_name

Z Gastroenterol

authors

Foltys D,Moench C,Burck I,Hoppe-Lotichius M,Schad A,Teufel A,Heise M,Otto G

doi

10.1055/s-2008-1027318

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

689-94

issue

7

eissn

0044-2771

issn

1439-7803

journal_volume

46

pub_type

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