Abstract:
:A new carbon paste electrode selective for piribedil (PD) was prepared and fully characterized in terms of composition, usable pH range, response time and thermal stability. The electrode active recognition is by liquid ion-exchange mechanism via the use of piribedil phosphomolybdate as ion-exchanger dissolved in tricresyl phosphate as a more suitable solvent mediator for the paste. The modified electrode showed a Nernstian slope of 58.4+/-0.6 mV over the concentration range of 7.5 x 10(-7) to 1 x 10(-3)M with an average recovery of 98.3-101.0% and R.S.D. of 0.45-1.31%. The electrode exhibits good selectivity for PD with respect to a large number of inorganic cations, organic cations, sugars and amino acids. The developed electrode was successfully used for the potentiometric determination of PD in its aqueous solutions, pharmaceutical preparation, and urine in batch and flow injection analysis (FIA).
journal_name
J Pharm Biomed Analjournal_title
Journal of pharmaceutical and biomedical analysisauthors
Ibrahim Hdoi
10.1016/j.jpba.2005.02.006subject
Has Abstractpub_date
2005-07-15 00:00:00pages
624-32issue
4eissn
0731-7085issn
1873-264Xpii
S0731-7085(05)00111-1journal_volume
38pub_type
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