[Portopulmonary hypertension].

Abstract:

:Patients with portal hypertension may develop pulmonary complications such as hepatopulmonary syndrome (HPS) or portopulmonary hypertension (PPHT). PPHT is defined as elevated pulmonary pressure, elevated pulmonary vascular resistance, a normal pulmonary capillary wedge pressure, and portal hypertension in the absence of other known causes pulmonary hypertension. Various factors such as hyperdynamic circulation, volume overload, and circulating vasoactive mediators are suspected to be involved in the pathogenesis of PPHT. The prognosis of patients with severe PPHT is significantly reduced due to the risk of right heart failure. In patients with moderate to severe PPHT liver transplantation is associated with a significantly increased mortality. The chief symptom of PPHT may be dyspnoe in the presence of typical histomorphological alterations comparable with idiopathic pulmonary hypertension. Continuous intravenous application of prostacyclin is currently regarded as the treatment of choice for patients with severe PPHT. Inhaled prostacyclin or its analogue iloprost or oral treatment with the endothelin-receptor antagonist bosentan may be promising alternatives which should be further investigated in randomized controlled trials.

journal_name

Z Gastroenterol

authors

Halank M,Miehlke S,Kolditz M,Hoeffken G

doi

10.1055/s-2005-857926

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

677-85

issue

7

eissn

0044-2771

issn

1439-7803

journal_volume

43

pub_type

杂志文章,评审
  • Effect of long-term fasting of obese patients on pancreatic exocrine function, gastrointestinal hormones and bicarbonate concentration in plasma.

    abstract::The CCK- and secretin stimulated pancreatic volume, bicarbonate and enzyme secretion was investigated before and during fasting for 20 days in 12 obese subjects. Pancreatic function tests were performed at the start of the fasting period and on the 10th and 20th day. In an additional and comparable group of 8 obese pa...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Fölsch UR,Dreessen UW,Talaulicar M,Willms B,Creutzfeldt W

    更新日期:1984-07-01 00:00:00

  • [Endoscopic tumor-cell diagnosis within the region of duodenum].

    abstract::The technique spontaneously or siphoned after cholecystokinin stimulation. Our technique of cell collection within the region of the duodenum, the pancreas and the bile-ducts have been optimal performed by duodenoscopical methods. From the papilla of Vater, the cell brush abrasion is used. Pancreatic secretions are ob...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Witte S

    更新日期:1976-07-01 00:00:00

  • Impaired bolus clearance in combined high-resolution esophageal manometry and impedance measurement helps to differentiate between esophagogastric junction outflow obstruction and achalasia.

    abstract::Introduction and aims High-resolution esophageal manometry (HRM) has improved the diagnostic work-up of esophageal motility disorders. Simultaneous evaluation of bolus clearance delivers useful information about the function of tubular esophagus. We assessed bolus clearance in a combined HRM-impedance examination for ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-0042-121267

    authors: Zizer E,Seufferlein T,Hänle MM

    更新日期:2017-02-01 00:00:00

  • [Chronic erosion of the stomach in the anastomotic region (authors' transl)].

    abstract::Report about 5 cases with a chronic erosion with granulation tissue formation of the mucosa of the resected stomach in the gastroenterostomotic area. These lesions appeared endoscopically as discoloration, or as small elevation of the mucosa or as a distinct polyp. One case with a more extensive granulation tissue for...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Dirschmid K

    更新日期:1982-03-01 00:00:00

  • [Determination of bile acids by radioimmunoassays (author's transl)].

    abstract::The present paper, based on the current literature, considers the practical aspects of bile acid radioimmunoassays. The problems associated with the raising of specific antisera and their characterization are discussed. Features of assay design for bile acids are considered. Solid-phase radioimmunoassays are described...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Matern S,Gerok W

    更新日期:1978-03-01 00:00:00

  • [Phospholipase A2--acute phase protein after liver surgery?].

    abstract:INTRODUCTION:The exact source of phospholipase A2 is unknown. In this context the liver is discussed because the secretion of phospholipase A2 could be initiated during an acute phase response. PATIENTS AND METHODS:Three groups of patients were prospectively established: A liver resection (n = 12); B control (n = 22; ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Gerhard F,Treusch H,Hofmann GE,Büssow M,Hanisch E

    更新日期:1997-04-01 00:00:00

  • [Diagnosis of celiac disease].

    abstract::In spite of modern diagnostic possibilities, the diagnosis of celiac disease is still challenging for the physician. This is due to the great variability of the clinical presentation. Nowadays, the classical symptoms like diarrhea, weight loss and abdominal pain are seen less often. It has become evident that celiac d...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2005-858656

    authors: Holtmeier W

    更新日期:2005-11-01 00:00:00

  • [Spontaneous and DL-penicillamine-induced renal copper excretion in liver diseases (author's transl)].

    abstract::The levels of cupriuresis before and after DL-Penicillamine have been investigated in 168 cases. The mean copper excretion before Penicillamine in chronic activ liver disease, chronic persistant hepatitis, cirrhosis and in transitional cases of aggressiv chronic hepatitis and primary biliary cirrhosis ranged from 29 g...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Friedrich K,Henning H

    更新日期:1979-03-01 00:00:00

  • [Actors in liver transplantation advocate greater transparency and systematic evaluations of transplant centres].

    abstract:BACKGROUND:Following the introduction of the MELD score, the survival rates have worsened after liver transplantation (LTX) in Germany. Existing organ shortages, shorter survival rates after LTX, and failures in the liver allocation process provide true challenges. Facilitated by a structured questionnaire, the appropr...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-0034-1366290

    authors: Roeb E,Graf J,Meyer HJ

    更新日期:2014-08-01 00:00:00

  • [Anorectal motility in systemic scleroderma].

    abstract::We prospectively compared esophageal and rectal motility data from 7 patients with progressive systemic sclerosis (4 females, 3 males) to esophageal recordings in 22 and anorectal recordings in 9 healthy controls. All patients with sclerosis exhibited motility disturbances in the lower esophageal sphincter (LES): LES ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Frieling T,Enck P,Bremer G,Lübke HJ,Berges W,Wienbeck M

    更新日期:1988-11-01 00:00:00

  • [Gastrointestinal bleeding in portal hypertension in liver cirrhosis].

    abstract::There are three major goals in the prophylaxis and treatment of upper gastrointestinal bleeding in portal hypertensive patients: prophylaxis of the first bleeding episode, therapy of active bleeding and prophylaxis of recurrent bleeding. Several therapeutic options are available: non-selective beta-blockers are the tr...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2004-813909

    authors: Biecker E,Heller J,Appenrodt B,Schepke M,Sauerbruch T

    更新日期:2005-01-01 00:00:00

  • [Pancreatic metastases of renal cell carcinomas - evaluation of the contrast behavior at echo-enhanced power-Doppler sonography in comparison to primary pancreatic tumors].

    abstract:BACKGROUND:Renal cell carcinomas are the most common primary tumors leading to pancreatic metastases. The differentiation of metastases from primary pancreatic tumors is important for the prognosis. Echo-enhanced power-Doppler sonography may be used for the differential diagnosis of tumors. In this study, the contrast ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2001-16690

    authors: Rickes S,Flath B,Unkrodt K,Ocran K,Neye H,Lochs H,Wermke W

    更新日期:2001-08-01 00:00:00

  • [Pancreatic pain: a clinical-experimental study].

    abstract::In 26 patients endoscopic-radiologic pancreography routinely performed caused severe pain with certain origin from pancreatic glan. Pain could be stopped immediately and with constant effect by lingual application of nitroglycerine. According to these informations we suppose that pancreatic pain is started by vascular...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Rehner M,Schilling D,Soehendra N,Werner B

    更新日期:1976-11-01 00:00:00

  • [S3-guidelines for diagnosis and treatment of gallstones. German Society for Digestive and Metabolic Diseases and German Society for Surgery of the Alimentary Tract].

    abstract::This guideline provides evidence-based key recommendations for diagnosis and therapy of gallstones and upgrades version 2000. It was developed by an interdisciplinary team of gastroenterologists, surgeons, radiologists, geneticists, external comparative quality assurance and patient support groups under the auspices o...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,实务指引

    doi:10.1055/s-2007-963437

    authors: Lammert F,Neubrand MW,Bittner R,Feussner H,Greiner L,Hagenmüller F,Kiehne KH,Ludwig K,Neuhaus H,Paumgartner G,Riemann JF,Sauerbruch T,Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten.,Deutschen Gesellschaft fü

    更新日期:2007-09-01 00:00:00

  • [Severe protracted cholestasis after general anesthesia in a patient with Alagille syndrome].

    abstract::A 27-year-old female patient with partial Alagille's syndrome (hypoplasia of the intrahepatic bile ducts, typical facial dysmorphism and skeletal anomalies) developed a marked cholestasis (total bilirubin 59 mg/dl), decrease of liver synthesis tests and ascites four weeks after gynecological surgery with general anest...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Müller C,Jelinek T,Endres S,Loeschke K

    更新日期:1996-12-01 00:00:00

  • [Obstacles and facilitators of conducting studies - the perspective of colorectal cancer centers' coordinators].

    abstract:INTRODUCTION:Clinical trials and health services research are crucial pillars for improving patient care. This paper examines factors inhibiting and promoting the study activity and the knowledge and use of trial registries (e. g. DRKS, StudyBox) as an opportunity to learn about existing studies. MATERIAL AND METHODS:...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-0041-111633

    authors: Kowalski C,Ferencz J,Benz S,Post S,Seufferlein T,Stinner B,Penzes O,Wesselmann S

    更新日期:2016-05-01 00:00:00

  • [Early gastric cancer, results in a county hospital (author's transl)].

    abstract::In a nine-year period, 46 patients with early gastric cancer were diagnosed and operated at a county hospital. Fiberscopy of the stomach raised the percentage of early gastric cancer from 1% in a five year pre-endoscopic period to 11.9% with endoscopy. On an average, subjects with early gastric cancer were 8 years you...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Schmid E,Gehl H,Blaich E,Haag S,Lorentz H,Kovarik P,Rettenmayr K,Schwarzkopf H

    更新日期:1981-02-01 00:00:00

  • Comparison of maximal postprandial serum cholylglycine concentration with the retention of 75Se-homotaurocholic acid in ileal dysfunction.

    abstract::The retention of 75Se-homotaurocholic acid (75SeHCAT) was measured in 12 healthy controls and in 21 patients with Crohn's disease and compared with the maximum postprandial rise in the serum concentration of cholylglycine (CG) in order to detect bile acid malabsorption. The retention of 75SeHCAT was lowered in all pat...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Karbach U,Singe CC,Mähtricht M,Ewe K

    更新日期:1989-05-01 00:00:00

  • Effect of ursodeoxycholic acid on the inflammatory activity of indomethacin-induced intestinal inflammation in rats.

    abstract::The beneficial effects of ursodeoxycholic acid (UDCA) in primary biliary cirrhosis are supposed to be mediated in part by immunological mechanisms. In this study, we have tested whether ursodeoxycholic acid also ameliorates intestinal inflammation induced by indomethacin in rats. Intestinal inflammation was induced in...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Kullmann F,Gross V,Rüschoff J,Arndt H,Benda W,Winkler von Mohrenfels A,Schölmerich J

    更新日期:1997-03-01 00:00:00

  • [Massive upper gastrointestinal bleeding as first clinical manifestation of pseudoxanthoma elasticum (author's transl)].

    abstract::We describe a patient with a "cryptogenic" massive upper gastrointestinal bleeding due to a pseudoxanthoma elasticum, recognized only postoperatively. She underwent twice emergency abdominal surgery with total gastrectomy and partial jejunal resection, with a complicated postoperative course. An insufficient enteral a...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Keim HJ,Holtermüller KH,Walter U,Bork K,Rothmund M,Gabbert H

    更新日期:1980-01-01 00:00:00

  • Helicobacter pylori and congestive gastropathy.

    abstract::This study evaluates the prevalence and significance of Helicobacter pylori (H. Pylori) infection in patients with portal hypertension. 118 patients were selected, i. e. 90 patients with portal hypertension (66 males, 24 females, mean age 49.1 +/- 2.1 years) and 28 noncirrhotic patients with nonulcerative dyspepsia as...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Bahnacy A,Kupcsulik P,Elés ZS,Jàray B,Flautner L

    更新日期:1997-02-01 00:00:00

  • Incidence, clinical management and outcomes of esophageal perforations after endoscopic dilatation.

    abstract:BACKGROUND:Esophageal dilatation is performed for the treatment of anatomic and sometimes functional narrowing of the esophageal lumen caused by a variety of benign and malignant conditions. Esophageal perforation is the major complication associated with endoscopic dilatation. AIM:The object of this study was to asse...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2007-963558

    authors: Fry LC,Mönkemüller K,Neumann H,Schulz HU,Malfertheiner P

    更新日期:2007-11-01 00:00:00

  • Gastric schwannoma as a rare differential diagnosis of pleural effusion.

    abstract::We report a case of solitary gastric schwannoma that initially manifested with recurrent left pleural effusion caused by an inflammatory reaction. A 75-year-old female was primarily admitted with progressive dyspnoea and left sided effusion. History as well as clinical examination, gastroscopy, computed tomography (CT...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2002-35416

    authors: Janowitz P,Meier F,Reisig J

    更新日期:2002-11-01 00:00:00

  • [Leptomeningeal carcinomatosis as a rare metastatic spreading of BRAF-mutated microsatellite stable colon cancer].

    abstract::Leptomeningeal carcinomatosis is a rare but serious complication of solid tumors such as melanoma, breast and lung cancer, as well as gastrointestinal carcinomas. Its clinical manifestation is highly variable, presenting as radicular pain with or without neurological deficits, as well as with headaches and hallucinato...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-0043-109025

    authors: Höblinger A,Weber S,Tschirner F,Kröber S,Streetz K

    更新日期:2017-07-01 00:00:00

  • [NASH -- nonalcoholic steatohepatitis].

    abstract::Nonalcoholic steatohepatitis describes a hepatic disorder with the typical characteristics of an alcoholic pathogenesis without alcohol consumption. It was first described in 1962 and named NASH by Ludwig et al. 1980. Many researchers worked on this disease since this time. It represents the hepatic manifestation of t...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2003-36679

    authors: Blechacz B,Stremmel W

    更新日期:2003-01-01 00:00:00

  • [Plasmaperfusion through activated charcoal and amberlite XAD-7 in dogs with liver failure induced by yellow phosphorus (author's transl)].

    abstract::Various sorbents were tested in-vitro for their ability to support hepatic excretory and detoxification functions, and their in-vivo perfusion with plasma was studied in an animal experiment. Amino acids, particularly phenylalanine and tyrosine, were strongest bound by activated charcoal, while Amberlite XAD-7 removed...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Horak W,Polterauer P,Renner F,Silberbauer K,Rauhs R,Mühlbacher F,Funovics J

    更新日期:1979-02-01 00:00:00

  • Verrucous carcinoma of the esophagus - a case report and literature review.

    abstract:BACKGROUND: Verrucous carcinoma of the esophagus is a rare disease leading to dysphagia, chest pain, and weight loss. The diagnosis is difficult because even repeated biopsies are often without tumor evidence. We present a patient with verrucous carcinoma of the esophagus and a literature review. CASE REPORT: A 64-yea...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:10.1055/a-1231-5820

    authors: Frieling T,Kreysel C,Blank M,Müller D,Euler P,Melchior I,Wullstein C,Hemmerlein B

    更新日期:2020-10-01 00:00:00

  • Non-invasive evaluation of activity in inflammatory bowel disease by power Doppler sonography.

    abstract:BACKGROUND:To study the vascularization in the diseased bowel wall by power Doppler sonography in patients with inflammatory bowel disease. PATIENTS AND METHODS:The diseased bowel wall was investigated in 99 patients with inflammatory bowel disease (60 patients with Crohn's disease and 39 patients with ulcerative coli...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2002-22325

    authors: Heyne R,Rickes S,Bock P,Schreiber S,Wermke W,Lochs H

    更新日期:2002-03-01 00:00:00

  • [Modification of alcohol-induced pancreatic damage in rats by soybean diet].

    abstract::Alcohol-induced hypersecretion probably contributes to chronic alcoholic pancreatitis. Feeding of raw soybean flour or soybean trypsin inhibitor also stimulates protein secretion of the pancreas. Therefore, we tested whether or not the pancreatic damage is increased by additional feeding of raw soybean flour in rats f...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Siegmund E,Jonas L,Dummler W

    更新日期:1994-02-01 00:00:00

  • [Diagnosis, staging and therapy of gastric cancer].

    abstract::In spite of a continuously decreasing incidence in Western countries, gastric cancer remains a major health problem world-wide and a leading cause of cancer-related deaths. The molecular pathogenesis of the vast majority of sporadic tumours has not yet been clarified in detail, while for some familial cancer types cau...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2004-813342

    authors: Menges M

    更新日期:2004-08-01 00:00:00