Contributions from lateral interaction mechanisms to the human ERG can be studied with a two-frequency method.

Abstract:

:We present a two-frequency method to investigate lateral interaction components (liERGs) in the human electroretinogram. Adjacent half cycles of sinusoidal gratings were modulated sinusoidally with different temporal frequencies f1 and f2. The liERGs were defined by the Fourier components at the intermodulation frequencies /f1 - f2/ and f1 + f2 which indicate nonlinear interactions between the half cycles. Significant liERGs were found in all subjects with a monotonic increase of the liERG magnitude in the spatial frequency range from f(s)=0.07 to 2.4 cpd. When /f1 - f2/ was below 5 Hz, liERGs were masked by noise intrusions. In a control experiment we demonstrated that the liERGs were not evoked by stray light artifacts. The liERGs may help to further differentiate the responses that are evoked by patterned stimuli within the retina.

journal_name

Vision Res

journal_title

Vision research

authors

Meigen T,Prüfer R,Reime S,Friedrich A

doi

10.1016/j.visres.2005.06.025

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

2862-76

issue

22

eissn

0042-6989

issn

1878-5646

pii

S0042-6989(05)00312-3

journal_volume

45

pub_type

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