Responses and receptive fields of amacrine cells and ganglion cells in the salamander retina.

Abstract:

:Retinal amacrine cells (ACs) and ganglion cells (GCs) have been shown to display large morphological diversity, and here we show that four types of ACs and three types of GCs exhibit physiologically-distinguishable properties. They are the sustained ON ACs; sustained OFF ACs; transient ON-OFF ACs; transient ON-OFF ACs with wide receptive fields; sustained ON-center/OFF-surround GCs; sustained OFF-center/ON-surround GCs and transient ON-OFF GCs. By comparing response waveforms, receptive fields and relative rod/cone inputs of ACs and GCs with the corresponding parameters of various types of the presynaptic bipolar cells (BCs), we analyze how different types of BCs mediate synaptic inputs to various ACs and GCs. Although more types of third-order retinal neurons may be identified by more refined classification criteria, our observations suggest that many morphologically-distinct ACs and GCs share very similar physiological responses.

journal_name

Vision Res

journal_title

Vision research

authors

Zhang AJ,Wu SM

doi

10.1016/j.visres.2010.01.009

subject

Has Abstract

pub_date

2010-03-17 00:00:00

pages

614-22

issue

6

eissn

0042-6989

issn

1878-5646

pii

S0042-6989(10)00022-2

journal_volume

50

pub_type

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