Abstract:
:This article reviews the epidemiology of weight gain and diabetes mellitus in general and in patients with severe mental illness in particular. Body mass index is defined, and possible predictors for weight gain in patients receiving antipsychotic medications are also enumerated. Information on risk of association with type 2 diabetes mellitus is described, as well as information on dyslipidemias within the rubric of the metabolic syndrome. Recent consensus panel reports and their recommendations for ongoing patient monitoring are reviewed. The issue of switching antipsychotic medication in the context of a developing metabolic disorder is discussed with regard to appropriately balancing risk and benefits. Collaborative treatment between a psychiatrist and an endocrinologist is encouraged. The primary care physician may be required to fulfill both roles.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Citrome L,Blonde L,Damatarca Cdoi
10.1097/01.smj.0000167621.49292.11subject
Has Abstractpub_date
2005-07-01 00:00:00pages
714-20issue
7eissn
0038-4348issn
1541-8243journal_volume
98pub_type
杂志文章,评审abstract:OBJECTIVES:Obstructive sleep apnea (OSA) is a prevalent disorder that is associated with multiple medical consequences. Although in-laboratory polysomnography is the gold standard for the diagnosis of OSA, portable monitors have been developed and studied to help increase efficiency and ease of diagnosis. We aimed to a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000543
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:A retrospective cross-sectional study was performed to assess the prevalence of elevated alkaline phosphatase (ALP) in patients infected with human immunodeficiency virus (HIV) and to determine the relation between ALP and specific antiretroviral therapy (ART). METHODS:A total of 2990 patients were included...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000500
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Chlamydia is the most commonly reported infectious disease in the United States, yet many women at risk for chlamydia infection are not being tested. METHODS:We conducted a chlamydia screening study (Phase I) and retrospective medical chart review (Phase II) of 199 women from 16 to 40 years of age attending...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000053673.13882.00
更新日期:2003-09-01 00:00:00
abstract::We have described a patient with long-standing chronic granulocytic leukemia. Although most patients with this disorder eventually have a picture of acute leukemia (blast crisis), this patient had massive thrombocytosis (platelet count greater than 5.000 x 10(9)/L) without major symptoms, but he died after transfusion...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198804000-00029
更新日期:1988-04-01 00:00:00
abstract::The use of psychostimulants as antidepressants remains controversial in the field of psychiatry. While methylphenidate hydrochloride (MPH) and dextroamphetamine (DA) are often considered to be equivalent drugs, differences in their neurobiologic mechanism of action may account for different clinical response patterns....
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199210000-00012
更新日期:1992-10-01 00:00:00
abstract::Mineral oil scrapings from an infant with a persistent, puzzling, generalized eruption revealed the mite, Sarcoptes scabiei. Various diagnostic technics and treatment for scabies are discussed. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197505000-00008
更新日期:1975-05-01 00:00:00
abstract:BACKGROUND:Use of mucolytic agents that result in reduced mucous viscosity of the gastric mucous has been suggested to have an additive effect in curing Helicobacter pylori infection. METHODS:Seventy Hpylori-positive patients were given either eradication treatment consisting of 500 mg clarithromycin bid and 30 mg lan...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000182486.39913.da
更新日期:2005-11-01 00:00:00
abstract::All indexed cases of typhoid fever occurring in children over a ten-year period in Jacksonville, Fla, were studied retrospectively. This review revealed that anorexia was the most common gastrointestinal complaint and that neurologic symptoms and signs were nearly as common as gastrointestinal signs. There was a signi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197902000-00008
更新日期:1979-02-01 00:00:00
abstract::Interruption of the inferior vena cava by the transvenous placement of a filter or umbrella effectively prevents pulmonary embolism by acting primarily as a physical barrier to emboli. Such a device will be effective only if the site of thrombosis is distal to the planned placement site. We have presented two cases in...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198906000-00025
更新日期:1989-06-01 00:00:00
abstract::In this study, the pelvic retroperitoneal anatomy was dissected during 140 consecutive exploratory laparotomies for benign gynecologic disease. In addition, 110 bilateral hypogastric artery ligations were done both to teach the technique and to attempt to determine whether such a procedure reduces blood loss in electi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198703000-00005
更新日期:1987-03-01 00:00:00
abstract::Six patients characterized by psychopathic behavior were treated with lesions placed in the center median nucleus of the thalamus. There was marked improvement of the psychopathic behavior in five patients. One patient with unilateral thalamotomy was parqially improved. Four of the six patients have been productive an...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197504000-00013
更新日期:1975-04-01 00:00:00
abstract::A 54-year-old woman, perhaps the oldest living American black with homozygous beta thalassemia, has had a relatively benign clinical course since her case was first reported two decades ago. Despite progressive splenomegaly, she has remained active without blood transfusions. This case emphasizes the mildness of homoz...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197609000-00041
更新日期:1976-09-01 00:00:00
abstract::A woman with stable diabetes presented with hypoglycemia and decreased insulin requirement. Further history suggested decreasing pituitary function. Laboratory tests confirmed pituitary deficiencies, associated with her increased insulin sensitivity. It may be helpful to be aware of this syndrome when dealing with dia...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198001000-00033
更新日期:1980-01-01 00:00:00
abstract::Using a phylogenic classification of the spine, one can identify precisely the numerical location of any vertebra or disc, including vertebrae with junctional anomalies at transitional zones. Such precision permitted comparisons of myelographic reports of sites of disc disease with the actual levels of extradural defo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197909000-00017
更新日期:1979-09-01 00:00:00
abstract:OBJECTIVES:The authors sought to explore patients' views about discussing spiritual issues with primary care physicians, including perceived barriers to and facilitators of discussions. METHODS:The study was a qualitative, semistructured interview of 10 chronically or terminally ill patients who were deliberately sele...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000146486.69217.EE
更新日期:2004-12-01 00:00:00
abstract::Systemic lupus erythematosus presents various clinical manifestations. The coexistence of systemic lupus erythematosus and celiac sprue has been rarely reported. We present a patient who had systemic lupus erythematosus with malabsorption demonstrating characteristic clinical and pathologic findings of celiac sprue (g...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199506000-00018
更新日期:1995-06-01 00:00:00
abstract::Bile drainage through normal lymphatic pathways has been described, but bile drainage from the liver to the duodenum via lymphatic collaterals has not. We have described a patient with a common bile duct stricture and lymphatic drainage of bile into the duodenum. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198401000-00028
更新日期:1984-01-01 00:00:00
abstract::The University of Virginia Department of Medicine has reorganized its adult diabetic ambulatory care program to provide optimal primary care and subspecialty services. This new program, the Diabetes Consult Service of the University Medical Associates, is organized to provide primary care by a single physician in addi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::In a series of 565 morbidly obese patients having one of five gastric bariatric procedures done at North Carolina Memorial Hospital between May 1975 and December 1982, 55 patients had 58 complications requiring reoperation. These complications included a leak from the stomach or anastomosis, stomal obstruction, and su...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198505000-00009
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND:Hepatitis secondary to infection with the hepatitis C virus (HCV) is one of the most common causes of viral hepatitis worldwide. Multiple extrahepatic manifestations of HCV infection have been recognized. Dilated and hypertrophic cardiomyopathy associated with HCV infection have been recently described in th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31822462e2
更新日期:2011-08-01 00:00:00
abstract::We have described three patients with diabetes and renal insufficiency who had hyperkalemia during heparin therapy. These cases lend support to previous findings, and emphasize the clinical importance of this entity. We believe that heparin-induced hyperkalemia is a potentially life-threatening problem that is more co...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198711000-00029
更新日期:1987-11-01 00:00:00
abstract::A variant of hereditary hemorrhagic telangiectasia may be gastrointestinal bleeding with no other classical symptoms. This case demonstrates the effectiveness of surgical resection as treatment of duodenal bleeding from telangiectatic lesions. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198703000-00024
更新日期:1987-03-01 00:00:00
abstract::Giant cell arteritis has been thought to occur only in white patients. There have been several recent reports of this disorder to blacks, however, and this case of biopsy-proven giant cell arteritis in a black patient indicates the diagnosis should be considered in any elderly patient with typical symptoms regardless ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197909000-00045
更新日期:1979-09-01 00:00:00
abstract::We describe a rare occurrence of comorbidity of schizophreniform disorder and borderline personality disorder as an initial patient presentation. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199803000-00013
更新日期:1998-03-01 00:00:00
abstract::We reviewed 76 cases of the empty sella syndrome. Headache was the chief complaint in 47 cases (62%), and 45 patients (60%) presented with signs and symptoms related to increased intracranial pressure and/or pituitary dysfunction. The CSF pressure was elevated in 35 of the 62 patients who had lumbar puncture, suggesti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract::An elderly woman complaining of a gait disorder was found to have the GALOP syndrome (gait ataxia, late-onset polyneuropathy). She exhibited mild distal weakness and sensory loss in the legs, a positive Romberg, and an unsteady gait. Serum immunofixation disclosed a monoclonal IgM-kappa protein. There was specific IgM...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000117799.38569.B8
更新日期:2004-04-01 00:00:00
abstract::Review of 185 consecutive Muller total hip arthroplasties five to nine years after operation showed that 14 patients had died and that three deaths were directly related to the surgery. Of these, 37 patients (54 hips) could not be located and were excluded. Another patient, nonambulatory for an unrelated cause, was al...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract:BACKGROUND:Primary care providers (PCPs) have limited training in recognizing common skin disorders, and additional emphasis may be placed on laboratory evaluation, including skin biopsies. METHODS:Primary care providers in Miami, Fla, were surveyed regarding skin biopsy and excision practices and histologic interpret...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::A controlled trial of treatment of chronic osteomyelitis caused by Staphylococcus aureus compared nafcillin alone with nafcillin plus rifampin for a six-week period. Treatment was well tolerated, the only adverse effect being mild neutropenia in four of 18 patients; no toxicity was observed from rifampin. Eight of ten...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/00007611-198608000-00008
更新日期:1986-08-01 00:00:00
abstract::Like the introduction of bare metal stents (BMS), that of drug-eluting stents (DES) represented a quantum leap in the interventional cardiology community's ongoing efforts to conquer restenosis. However, recent concerns over late thrombosis (LT) have tempered the initial enthusiasm. Nonetheless, when compared with BMS...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000286752.67205.e0
更新日期:2008-02-01 00:00:00