GALOP syndrome: case report with 7-year follow-up.

Abstract:

:An elderly woman complaining of a gait disorder was found to have the GALOP syndrome (gait ataxia, late-onset polyneuropathy). She exhibited mild distal weakness and sensory loss in the legs, a positive Romberg, and an unsteady gait. Serum immunofixation disclosed a monoclonal IgM-kappa protein. There was specific IgM binding to galopin, a central nervous system white matter antigen. Periodic treatment with intravenous immunoglobulin has alleviated her neurologic symptoms. She has now been followed for 7 years and maintained significant improvement in neurologic symptoms and signs.

journal_name

South Med J

journal_title

Southern medical journal

authors

Alpert JN

doi

10.1097/01.SMJ.0000117799.38569.B8

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

410-2

issue

4

eissn

0038-4348

issn

1541-8243

journal_volume

97

pub_type

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