Abstract:
INTRODUCTION:Cardiopulmonary exercise testing (CPET) is used to evaluate the severity of interstitial lung diseases, particularly when lung function is normal. The aim of this study was to analyse exercise capacity of patients with alveolar proteinosis. METHODS:We studied 7 patients undergoing alveolar proteinosis (aged 38 +/- 5 years), Three patients complained of exertional dyspnoea, 2 had a reduced vital capacity and 5 had a DLCO of less than 75% predicted. CPET was performed on a bicycle ergometer using a standard incremental protocol. RESULTS:CPET was symptom limited for all patients.. At peak exercise, VO2 was severely reduced (19.5 +/- 5.2 ml/kg/min, 58 +/- 9%). All patients developed hyperventilation. Ventilatory reserve was 42 +/- 11% of MMV, and dead space ratio (Vd/Vt) reached 0.29 +/- 0.05. Cardio-circulatory adaptation was normal (maximum heart rate 83 +/- 9%; VO2/heart rate 70 +/- 10%). Six patients exhibited gas exchange abnormalities at peak exercise (including 4 patients having a normal vital capacity): P(A-a)O2 56 +/- 18mm Hg; PaO2 65 +/- 18 mm Hg. CONCLUSION:Patients undergoing alveolar proteinosis have severe impairment of aerobic capacity and gas exchange on exercise. CPET appears to be useful for therapeutic management.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Bautin N,Fournier C,Marie E,Robin S,Neviere R,Wallaert Bdoi
10.1019/200530119subject
Has Abstractpub_date
2005-12-01 00:00:00pages
943-50issue
6 Pt 1eissn
0761-8425issn
1776-2588pii
S0761-8425(05)85725-0journal_volume
22pub_type
杂志文章abstract::Passive smoking, measured in practice by using specific biomarkers, is a well known factor of morbidity and mortality. The main victims are children, often starting from conception, but adults are not spared. Many respiratory diseases are caused and/or worsened by passive smoking and environmental tobacco smoke (ETS) ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(09)74696-0
更新日期:2009-06-01 00:00:00
abstract::In a prospective study the level of carcinoembryonic antigen (ACE) were simultaneously measured in plasma and bronchoalveolar lavage liquid (LBA), in fifteen patients suffering from bronchopulmonary cancer and fifteen patients suffering from non-malignant pulmonary disease. In these two groups the level of ACE in LBA ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::The authors report an "analytic epidemiological" study, showing the risk of relapse in tuberculous patients in the Bas-Rhin in 1967 to 1977. This was possible thanks to statutory notification of tuberculous cases, with an index updated by annual returns. The study relates to French subjects notified as new cases of al...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Non malignant asbestos diseases are dominated numerically by pleural plaques. This form of circumscribed fibrosis of the parietal pleural is generally asymptomatic and its potential for evolution is weak. More rarely diffuse pleural fibrosis results from disease of the visceral pleura with a secondary fusion of the tw...
journal_title:Revue des maladies respiratoires
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doi:
更新日期:1999-01-01 00:00:00
abstract:INTRODUCTION:Smoke inhalation and respiratory complications are still the major causes of mortality in severely burned patients. STATE OF THE ART:The diagnosis is suspected clinically on the basis of history and physical examination and can be confirmed bronchoscopically. Respiratory failure in burned patients occurs ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2005-06-01 00:00:00
abstract::The majority of smokers who stop smoking do it alone. The methods of stopping are aimed at helping those who cannot achieve this. The different methods used include psycho-therapy (individual-group), medication, and in the first place is nicotine chewing-gum (but also clonidine which opens a new perspective), aversive...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVES:To report the results of minimally invasive surgery in patients with stage I or II thymoma in the Masaoka classification. The reference technique is partial or complete thymectomy by sternotonomy. METHODS:A retrospective single-center study of a prospective database including all cases of thymoma operated f...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:2006-11-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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更新日期:2001-02-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2012-02-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1999-09-01 00:00:00
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2007-05-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2014-10-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
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journal_title:Revue des maladies respiratoires
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更新日期:2009-11-01 00:00:00
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journal_title:Revue des maladies respiratoires
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更新日期:1997-06-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2005-12-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 临床试验,杂志文章
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更新日期:2011-05-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2020-10-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00