Abstract：
:Some data suggest that survival in non small cell lung cancer (NSCLC) has improved in the last ten years. A comparison between large prospective therapeutic trials from 1979 to 2002 does show some progress but there are many biases, especially the Will Rogers effect, where stage migration due to new methods of diagnostic imaging and invasive staging procedures could improve actuarial survival in each stage. Prospective randomised trials comparing older and more recent treatments demonstrate some improvements, specifically perioperative chemotherapy in stages I-IIIA, chemo-radiation in unresectable stage III disease and new drugs in stage IV. However retrospective whole population studies fail to show a significant improvement in survival. These discrepancies could be explained by differences between whole populations and those selected for clinical trials. Moreover, the results of the therapeutic trials are not always applied in all unselected patients. In conclusion, NSCLC survival can be improved in a selected population. To reproduce this in the whole population all patients should be managed in accordance with the results of recent trials.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Milleron B,Lavolé A,Gounant Vsubject
Has Abstractpub_date
2005-12-01 00:00:00pages
8S137-42issue
6 Pt 2eissn
0761-8425issn
1776-2588pii
MDOI-RMR-12-2005-22-6-C2-0761-8425-101019-20050915journal_volume
22pub_type
杂志文章,评审abstract：BACKGROUND:To update full time educated youth data on smoking prevalence related to gender and to assess perception and behaviour related to smoking, we have led a self-administrated question-study from January to June 2002 in Abidjan with students from 8 to 22 years old. METHODS:Our population was divided in 3 groups...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(04)71410-2
更新日期：2004-09-01 00:00:00
abstract：:We report seven cases of seven pulmonary varicella occurring in seven adults without any previous history of known immunological deficit. In all the cases the vesicular eruption was diffuse, occurring after contact with a child presenting with benign varicella. The respiratory signs appeared five to seven days after t...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:The authors report a case of a plasma cell granuloma in a young woman of 19 with a past history of congenital rubella, presenting with repeated small haemoptyses related to a pedunculated endo-bronchial tumour. The diagnosis was only made per-operatively, permitting an effective excision. ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:This review highlights the numerous molecular biology findings in the field of lung cancer with potential therapeutic impact in both the near and distant future. Abundant pre-clinical and clinical data indicate that BRCA1 mRNA expression is a differential modulator of chemotherapy sensitivity. Low levels predict cispl...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2006-11-01 00:00:00
abstract：:The term "obstructive bronchiolitis" used in this review covers different clinicopathological aspects. On the one hand, it refers to "small airways disease", where bronchiolar narrowings are widespread, secondary to post inflammatory fibrotic changes linked to tobacco smoke or fibrogenic dust inhalation. These obstruc...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1987-01-01 00:00:00
abstract：:Despite the progress in therapeutic strategies, overall survival of stage III non small cell lung cancers (NSCLC) is poor. Currently, the standard treatment for unresectable locally advanced NSCLC is concurrent chemoradiotherapy. However, oesophagitis is a major toxicity and this schedule should be reserved for patien...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2007-10-01 00:00:00
abstract：:The authors report a case of post traumatic tetraplegia at the C1-C2 level in a young man of 16 with total respiratory paralysis treated with mechanical ventilation and a tracheotomy. Thirty months after the accident, an Avery S 232(1) diaphragmatic pacemaker was surgically implanted by the mediastinal approach. The t...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:We report a case of primary broncho-pulmonary cancer presenting as a round, fine walled cyst. Based on the observations in this case, and from the data in the literature, we suggest the characteristics of the radiology and scanning which should enable the neoplastic aetiology to be suspected. ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：INTRODUCTION:Six minutes walking test (6MWT) is regularly used in pulmonology. To minimize the risk of cross-infection, some patients must wear surgical mask at rest and sometimes during exercise. AIM OF THE STUDY:To evaluate the effect of wearing a surgical mask during 6MWT in healthy subjects. MATERIAL AND METHOD:I...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.rmr.2017.01.010
更新日期：2018-03-01 00:00:00
abstract：:A 28-year-old girl suffering from lysinuric protein intolerance was referred on account of severe chronic respiratory failure. Since childhood she had failure to thrive with chronic hyperammonaemia and interstitial lung disease but normal respiratory function. At the age of 21, she experienced haemoptysis and worsenin...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2010.06.022
更新日期：2010-09-01 00:00:00
abstract：:The phospholipid content of bronchoalveolar lavage (LBA) has been little studied till now. This work involved 96 LBA on 7 cases of allergic alveolitis, 11 cases of diffuse interstitial fibrosis (FID) and 42 of sarcoidosis. The liquid collected was submitted to a cellular study (cellularity, total and differential) and...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：UNLABELLED:Severe pneumonia due to cytomegalovirus in chronic obstructive pulmonary disease. INTRODUCTION:We describe two cases of immunocompetent patients with chronic obstructive pulmonary disease (COPD) who developed severe cytomegalovirus (CMV) pneumonia. The clinical and radiological context and CMV replication i...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2013.09.013
更新日期：2014-05-01 00:00:00
abstract：:An analysis of the way the pharyngeal musculature modulates the caliber of the pharynx is important to better understand and treat obstructive sleep apnea syndromes. The caliber of the pharynx at the soft palate depends on the action of the tensor veli, the palatoglossus, the palatopharyngeus and the uvula muscles. At...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVES:To estimate the prevalence of treated chronic obstructive pulmonary disease (COPD) and its associated costs by stage of severity. METHODS:The study was conducted on the 2011 data of the french general beneficiary sample database (EGB). EGB is a 1/97th sample of the whole population of the beneficiaries of t...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2014.10.731
更新日期：2015-09-01 00:00:00
abstract：:The authors explain the different types of legislation, according to dissimilar systems, which enable the Social Security or private services to take charge of the care required for occupationally acquired asthma. They emphasize that compensation is currently specified in the different countries by official internatio...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：INTRODUCTION:Amyopathic dermatomyositis associated with anti-MDA5 autoantibodies is a rare and very recently described clinical entity. CASE REPORT:A 58-year-old woman was admitted with subacute onset of dyspnea (NYHA class IV) associated with cough, oligoarthritis of the wrists, myalgia and intermittent fever. Examin...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2014.02.010
更新日期：2014-11-01 00:00:00
abstract：:The diaphragm is the muscle most implicated in breathing. Its morphological exploration usually depends on pulmonary radiography, fluoroscopy, CT-scanning and MRI. Its function is evaluated by the classical respiratory functional tests, the measurement of maximum inspiratory and expiratory pressures, the transdiaphrag...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2017.02.005
更新日期：2017-06-01 00:00:00
abstract：INTRODUCTION:Acute pulmonary histoplasmosis (APH) is rare in an immunocompetent patient. We report a case of APH diagnosed by culture of broncho-alveolar lavage (BAL) in a patient presenting a pseudo-tumoral form with nodules progressing to cavitation. OBSERVATION:A 41 year-old male smoker was hospitalized with a pers...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2020.04.004
更新日期：2020-05-01 00:00:00
abstract：INTRODUCTION:In western countries, community-acquired pneumonias due to Klebsiella pneumoniae (Kp) are rare and associated with a poor prognosis and a high mortality. The severity is in part linked to the virulence of Kp. Immuno-depression, sepsis and visceral abscesses are frequently found, constituting other classica...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(09)72429-5
更新日期：2009-09-01 00:00:00
abstract：INTRODUCTION:Exhaled carbon monoxide (ECO) concentration provides an easy, fast and non invasive means of assessing smoking status. However, some difficulties have to be considered when interpreting ECO levels. BACKGROUND:CO is a non-specific biomarker of tobacco exposure. Its half-life is short (2-6 hours). CO reflec...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2009.09.004
更新日期：2010-04-01 00:00:00
abstract：:The authors report a case of a ruptured right subphrenic abscess causing a diffuse peritonitis complicating a chronic empyema. The authors recommend active treatment of purulent pleurisies, particularly when they are associated with a bronchopleural fistula. ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：:Surgery is the ultimate curative treatment for resectable non-small cell lung cancer (NSCLC). However, the prognosis for operated patients remains disappointing. Multiple randomized studies have shown that administering perioperative chemotherapy improves the prognosis and increases the cure rate by around 3-5%. The p...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2020.12.002
更新日期：2021-01-01 00:00:00
abstract：INTRODUCTION:Immunodepression induced by the human immunodeficiency virus (HIV) modifies the clinical, radiological and microbiological manifestations of pulmonary tuberculosis; leading to similarities between pulmonary tuberculosis and acute community-acquired bacterial pneumonia. A consequence is the high proportion ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2015.01.004
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:Despite recommendations, asthma remains poorly controlled in many countries. Asthmatic patients see pharmacy staff regularly to obtain medications. The aim of this study was to evaluate the attitude of pharmacists in Burkina Faso about dispensing asthma drugs. METHOD:A self-administered anonymous question...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2013.09.019
更新日期：2015-01-01 00:00:00
abstract：:A young man without any past history of note had taken isotretinoin for disfiguring acne before the summer season. He presented with a severe bilateral pneumonia, associated with dyspnoea two months after the start of treatment. On the pulmonary radiography there was a bilateral ground glass appearance which was worse...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Bronchocentric granulomatosis is a rare entity and has only recently been characterised. We report a case of a forty-three year old man presenting with multifocal bronchocentric granulomatosis which was revealed following some oto-rhino-laryngological and bronchopulmonary symptoms. The open lung biopsy confirmed the d...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:This cross sectional study took place with a self administered questionnaire between June and September 1999 and involved 1,388 subjects of whom 62.4% were men and 37.6% women. The total prevalence of smoking was 14.9%, ranging from 12.5% in paramedical staff to 15.5% in manual workers, 16.2% in doctors, 17.1% in labo...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
abstract：INTRODUCTION:The EOLE cohort aimed to describe, in routine clinical practice, the characteristics and management of patients receiving bevacizumab in combination with first-line metastatic chemotherapy for advanced metastatic or recurrent non squamous non-small cell lung cancer (nsNSCLC), as well as its efficacy and sa...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,多中心研究
doi：10.1016/j.rmr.2016.05.003
更新日期：2017-01-01 00:00:00
abstract：:The natural history and pathophysiology of chronic airflow obstruction (BPCO) remain poorly understood. Therapy cannot cure the disease but should be aimed at palliating its effects: to reduce dyspnoea, to improve the exercise performance, to minimise the complications, to stabilise the disease and improve the quality...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:We reviewed the records of 15 Human Immunodeficiency Virus (HIV) infected patients with pulmonary cryptococcosis (PC). PC was the first AIDS-defining manifestation in nine patients. HIV infection was identified simultaneously with the onset of PC in 4 patients. The CD4+ lymphocyte count was low in all cases (median, 2...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
