Initial experience with Minaxolone. A water-soluble steroid intravenous anaesthetic agent.

Abstract:

:Minaxolone has been used to induce anaesthesia, and in incremental doses to supplement nitrous oxide, in 100 patients undergoing minor surgical procedures. Half the patients received a small dose of fentanyl before induction. Minaxolone proved to be a satisfactory induction agent. The commonest complications were an increase in muscle tone and involuntary muscle movements, which in some patients occurred in the recovery period: their incidence was reduced by fentanyl. There was a notably low incidence of nausea and vomiting.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Punchihewa VG,Morgan M,Lumley J,Whitwam JG

doi

10.1111/j.1365-2044.1980.tb03805.x

subject

Has Abstract

pub_date

1980-02-01 00:00:00

pages

214-7

issue

2

eissn

0003-2409

issn

1365-2044

journal_volume

35

pub_type

临床试验,杂志文章,随机对照试验
  • Anaesthesia equipment malfunction.

    abstract::Anaesthetic equipment was studied to determine whether the accuracy was improved and failure rate decreased by routine maintenance and calibration by a biomedical technician. Each piece was evaluated, and then repaired and rechecked at intervals by the same technician. Equipment failures were divided into three types:...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1985.tb10505.x

    authors: Holley HS,Carroll JS

    更新日期:1985-01-01 00:00:00

  • Pulmonary oedema after ophthalmic regional anaesthesia in an unfasted patient undergoing elective surgery.

    abstract::An elderly female patient presenting for phaco-emulsification and intra-ocular lens implant under local anaesthesia developed pulmonary oedema after surgery and underwent emergency tracheal intubation. The pulmonary oedema may have been caused by her omission of routine oral diuretic medication before surgery and havi...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2001.01967.x

    authors: Taylor I,Watters M

    更新日期:2001-05-01 00:00:00

  • Assessing collateral circulation in the hand--four methods compared.

    abstract::Four ways to assess the collateral circulation in the hand were compared. No correlation was shown between the Doppler ultrasound method and those that used either the pulse monitor or the Ohmeda Biox 3700 pulse oximeter. The study was unable to confirm suggested benefits of these methods in assessing adequacy of coll...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1989.tb11452.x

    authors: Glavin RJ,Jones HM

    更新日期:1989-07-01 00:00:00

  • Anterior mediastinal masses: an anaesthetic challenge.

    abstract::A patient with a large anterior mediastinal mass with minimal respiratory symptoms presented for a diagnostic biopsy of the mass. A pre-operative thoracic computed tomographic scan demonstrated narrowing of the distal trachea, and right and left main stem bronchi. An awake intubation was done. Thiopentone and muscle r...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2044.1999.00961.x

    authors: Goh MH,Liu XY,Goh YS

    更新日期:1999-07-01 00:00:00

  • Intensive care medicine in rural sub-Saharan Africa.

    abstract::We undertook an audit in a rural Ugandan hospital that describes the epidemiology and mortality of 5147 patients admitted to the intensive care unit. The most frequent admission diagnoses were postoperative state (including following trauma) (2014/5147; 39.1%), medical conditions (709; 13.8%) and traumatic brain injur...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.13710

    authors: Dünser MW,Towey RM,Amito J,Mer M

    更新日期:2017-02-01 00:00:00

  • C-reactive protein in patients undergoing cardiac surgery.

    abstract::Among 25 patients undergoing cardiac surgery with the aid of cardiopulmonary bypass, 13 who recovered uneventfully all had normal (less than 2 mg/litre) levels of serum C-reactive protein pre-operatively. In contrast, 10 of the 12 patients who suffered from various postoperative complications, including two who died, ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1986.tb12696.x

    authors: Boralessa H,de Beer FC,Manchie A,Whitwam JG,Pepys MB

    更新日期:1986-01-01 00:00:00

  • Modified occlusion tests for the Bain breathing system.

    abstract::Undetected defects in the inner tube of the Bain coaxial anaesthetic breathing system may result in a greatly increased apparatus deadspace. Several authorities have advocated tests intended to detect inner tube problems; however, the efficacy of these tests has never been validated. In this study none of the tests we...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1991.tb09412.x

    authors: Heath PJ,Marks LF

    更新日期:1991-03-01 00:00:00

  • Comparison of the C-MAC videolaryngoscope with the Macintosh, Glidescope, and Airtraq laryngoscopes in easy and difficult laryngoscopy scenarios in manikins.

    abstract::The C-MAC comprises a Macintosh blade connected to a video unit. The familiarity of the Macintosh blade, and the ability to use the C-MAC as a direct or indirect laryngoscope, may be advantageous. We wished to compare the C-MAC with Macintosh, Glidescope and Airtraq laryngoscopes in easy and simulated difficult laryng...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2010.06307.x

    authors: McElwain J,Malik MA,Harte BH,Flynn NM,Laffey JG

    更新日期:2010-05-01 00:00:00

  • Pneumatic tourniquet paralysis following intravenous regional analgesia.

    abstract::A case of pneumatic tourniquet paralysis with permanent damage is presented. The importance of relating the cuff pressure to the cuff used, the arterial blood pressure and the shape of the arm is emphasised. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1987.tb04046.x

    authors: Larsen UT,Hommelgaard P

    更新日期:1987-05-01 00:00:00

  • Use of methohexitone, fentanyl and nitrous oxide for short surgical procedures.

    abstract::An anaesthetic technique for unpremedicated patients undergoing minor surgery is described. After the administration of atropine and fentanyl, anaesthesia was induced with methohexitone and maintained with nitrous oxide supplemented when necessary by further small doses of methohexitone. This technique provided good o...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1977.tb11595.x

    authors: Goroszeniuk T,Whitwam JG,Morgan M

    更新日期:1977-02-01 00:00:00

  • A simulation-based evaluation of two proposed alternatives to Luer devices for use in neuraxial anaesthesia.

    abstract::The National Patient Safety Agency has issued a Patient Safety Alert with the aim of eliminating Luer connectors from equipment for lumbar puncture and subarachnoid injections by 1 April 2011, and from all neuraxial and regional anaesthesia equipment in 2013. B-link (UK) Ltd and InterVene Ltd have produced non-Luer co...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2010.06537.x

    authors: Cook TM,Payne S,Skryabina E,Hurford D,Clow E,Georgiou A

    更新日期:2010-11-01 00:00:00

  • A comparison of four risk models for the prediction of cardiovascular complications in patients with a history of atrial fibrillation undergoing non-cardiac surgery.

    abstract::It is unclear how best to predict peri-operative cardiovascular risk in patients with atrial fibrillation undergoing non-cardiac surgery. This study examined the accuracy of the revised cardiac risk index and three atrial fibrillation thrombo-embolic risk models for predicting 30-day cardiovascular events after non-ca...

    journal_title:Anaesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1111/anae.14777

    authors: McAlister FA,Youngson E,Jacka M,Graham M,Conen D,Chan M,Szczeklik W,Alonso-Coello P,Devereaux PJ,vascular events in non-cardiac surgery patIents cohort evaluation (VISION) investigators.

    更新日期:2020-01-01 00:00:00

  • A disposable device for patient-controlled analgesia with fentanyl.

    abstract::A disposable nonelectronic patient-controlled analgesia device was used to deliver fentanyl after upper abdominal surgery. Pain relief was satisfactory and plasma fentanyl concentrations were similar to those obtained by other workers who used electronic patient-controlled analgesia devices. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1989.tb09151.x

    authors: Rowbotham DJ,Wyld R,Nimmo WS

    更新日期:1989-11-01 00:00:00

  • An unusual cause of neonatal respiratory distress. RDS in a neonate with a neuro-enteric cyst.

    abstract::A 2.5 kg male infant developed respiratory distress in the neonatal period. A diagnosis of idiopathic hyaline membrane disease was made and he was treated accordingly. At 24 hours of age he required intubation, and the immediate and dramatic improvement in his condition suggested that the original diagnosis was incorr...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1981.tb08817.x

    authors: Cahill JF

    更新日期:1981-08-01 00:00:00

  • Cerebral and regional organ perfusion in pigs during xenon anaesthesia.

    abstract::Little is known about the haemodynamic effects of inhaled xenon on regional organ perfusion. The aim of this study was to investigate the effect of 79% xenon ventilation on organ perfusion in pigs. We investigated 10 pigs, which were randomly allocated to receive either xenon 79% or total intravenous anaesthesia (TIVA...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2001.02322.x

    authors: Schmidt M,Marx T,Kotzerke J,Lüderwald S,Armbruster S,Topalidis P,Schirmer U,Reinelt H

    更新日期:2001-12-01 00:00:00

  • A safety block for scavenging systems.

    abstract::A safety block is described which protects the patient from expiratory obstruction when using scavenging systems, and provides the anaesthetist with a visual and auditory check on the functioning of the system. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1976.tb11981.x

    authors: Bethune DW,Collis JM,Latimer RD

    更新日期:1976-11-01 00:00:00

  • Comparison of the Intersurgical Solus laryngeal mask airway and the i-gel supralaryngeal device.

    abstract::Summary We compared the performance of the Intersurgical Solus laryngeal mask airway (LMA) with that of the i-gel in 120 patients of ASA physical status during general anaesthesia with respect to oropharyngeal leak pressure, peak airway pressure, airway manipulation, insertion time, fibreoptic view, ventilatory parame...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2010.06336.x

    authors: Amini S,Khoshfetrat M

    更新日期:2010-08-01 00:00:00

  • In vivo animal studies with sugammadex.

    abstract::A review is presented of animal studies of the selective steroidal neuromuscular blocking drug binding agent sugammadex. These studies demonstrate that sugammadex is faster in onset than the currently used acetylcholinesterase inhibitors, has no muscarinic effects, and is characterised by lack of adverse effects on ot...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.2008.05869.x

    authors: Booij LH,van Egmond J,Driessen JJ,de Boer HD

    更新日期:2009-03-01 00:00:00

  • From smartphone to bed-side: exploring the use of social media to disseminate recommendations from the National Tracheostomy Safety Project to front-line clinical staff.

    abstract::Traditional methods used to disseminate educational resources to front-line healthcare staff have several limitations. Social media may increase the visibility of these resources among targeted groups and communities. Our project aimed to disseminate key clinical messages from the National Tracheostomy Safety Project ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.14747

    authors: Ng FK,Wallace S,Coe B,Owen A,Lynch J,Bonvento B,Firn M,McGrath BA

    更新日期:2020-02-01 00:00:00

  • Application of MVBC equation to predict mixed venous blood concentrations of sevoflurane in cardiac anaesthesia.

    abstract::We have proposed an equation for estimating the real-time mixed venous blood concentration (MVBC) of isoflurane in cardiac anaesthesia. However, information related to the application of our method to sevoflurane is lacking. We studied 12 patients undergoing cardiac surgery and anaesthetised with sevoflurane. At diffe...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2005.04280.x

    authors: Ho WM,Hung WT,Wu CC,Shen CH,Yang NC,Hwang KL,Wong KC

    更新日期:2005-09-01 00:00:00

  • From Clover to computer. Towards programmed anaesthesia?

    abstract::The control of depth of anaesthesia has been viewed as a control-system problem the solution of which can involve both feedback and feedforward techniques. The nature of the problem in Clover's day and the solutions he found have been examined. A similar analysis has been made in respect of the modern anaesthetist. Fi...

    journal_title:Anaesthesia

    pub_type: 传,历史文章,杂志文章

    doi:10.1111/j.1365-2044.1979.tb06272.x

    authors: Mapleson WW

    更新日期:1979-02-01 00:00:00

  • A comparison of thiopentone and propofol with respect to the incidence of postoperative shivering.

    abstract::One hundred patients (69 female) undergoing surgical excision of three or more wisdom teeth were randomly allocated to receive either thiopentone or propofol for induction of anaesthesia. Other than the induction agent, the anaesthetic regimen was standardised for all cases. All patients were observed for 15 min after...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1994.tb04322.x

    authors: Singh P,Harwood R,Cartwright DP,Crossley AW

    更新日期:1994-11-01 00:00:00

  • Impact of postoperative nausea and vomiting in the surgical setting.

    abstract::Postoperative nausea and vomiting is one of the most common complications of inpatient and day case surgical procedures. In a climate where total cost of an illness is becoming increasingly important, postoperative nausea and vomiting is a major contributor to direct and indirect costs for both the hospital and patien...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.1994.tb03580.x

    authors: Hirsch J

    更新日期:1994-01-01 00:00:00

  • Red blood cell transfusion in surgery: an observational study of the trends in the USA from 2011 to 2016.

    abstract::Guidelines recommend restrictive red blood cell transfusion strategies. We conducted an observational study to examine whether the rate of peri-operative red blood cell transfusion in the USA had declined during the period from 01 January 2011 to 31 December 2016. We included 4,273,168 patients from all surgical subsp...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.14900

    authors: Nordestgaard AT,Rasmussen LS,Sillesen M,Steinmetz J,Eid AI,Meier K,Kaafarani HMA,Velmahos GC

    更新日期:2020-04-01 00:00:00

  • Propofol for long-term sedation in the intensive care unit. A comparison with papaveretum and midazolam.

    abstract::Thirty-seven patients with a wide range of illnesses were studied during mechanical ventilation of the lungs in an intensive care unit. Fifteen were sedated with a continuous propofol infusion, with analgesia provided by bolus doses of papaveretum. Twelve received a continuous infusion of papaveretum, supplemented by ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1990.tb14777.x

    authors: Harris CE,Grounds RM,Murray AM,Lumley J,Royston D,Morgan M

    更新日期:1990-05-01 00:00:00

  • Buscopan for the treatment of pain after laparoscopic sterilisation.

    abstract::We investigated the effect of Buscopan 20 mg, given at the end of surgery, on analgesic requirements in 44 ASA I and II patients presenting as day cases for laparoscopic sterilisation using Filshie clips. Patients were randomly allocated to receive either intravenous Buscopan 20 mg or saline placebo at the end of surg...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.2001.01528-2.x

    authors: Habib A,Sharpe P,Anderson S,Francis S,Davidson AC,Smith G

    更新日期:2001-02-01 00:00:00

  • A jet nebuliser for delivery of topical anesthesia to the respiratory tract. A comparison with cricothyroid puncture and direct spraying for fibreoptic bronchoscopy.

    abstract::Topical anesthesia of the respiratory tract for fibreoptic bronchoscopy was compared, in a single-blind study, inhaled from a simple and inexpensive jet nebuliser, administered by cricothyroid injection or by a 'spray-as-you-go technique'. Each technique was supplemented by spraying lignocaine through the fibrescope a...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1990.tb14504.x

    authors: Isaac PA,Barry JE,Vaughan RS,Rosen M,Newcombe RG

    更新日期:1990-01-01 00:00:00

  • Continuous intravenous anaesthesia with Althesin for resection of tracheal stenosis.

    abstract::The anaesthetic management of patients undergoing tracheal resection for tracheal stenosis and the advantage of the maintenance of spontaneous respiration without intubation of the distal tracheal segment is discussed. The case reports of two such patients using a continuous intravenous infusion of Althesin with maint...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1983.tb13931.x

    authors: Vyas AB,Lyons SM,Dundee JW

    更新日期:1983-02-01 00:00:00

  • Ketamine-diazepam anaesthesia in a patient with carcinoid syndrome.

    abstract::The use of ketamine in patients with carcinoid syndrome is controversial because of the catecholamine response to this agent. Prior administration of diazepam modifies the catecholamine response to ketamine and may make its use in such patients safe. The successful use of a diazepam-ketamine technique for anaesthesia ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1981.tb08862.x

    authors: Eisenkraft JB,Dimich I,Miller R

    更新日期:1981-09-01 00:00:00

  • Omeprazole for prophylaxis of acid aspiration in elective surgery.

    abstract::The aim of the study was to determine whether a single oral dose of omeprazole 40 mg is effective in increasing the pH of gastric residue above 2.5 at the time of anaesthetic induction in adult patients scheduled for elective gynaecological surgery. The patients were allocated to receive either chlorazepate dipotassiu...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1990.tb14327.x

    authors: Ng Wingtin L,Glomaud D,Hardy F,Phil S

    更新日期:1990-06-01 00:00:00