Remote effect of malignancy on the nervous system in children.

Abstract:

:A 13-year-old boy with Hodgkin's disease developed acute polyneuropathy and autoimmune hemolytic anemia. Sural nerve biopsy and postmortem examination demonstrated no metastatic involvement and a lack of cellular inflammatory infiltration in the nervous system. There was significant axonal degeneration in peripheral nerves and the dorsal funiculus. These findings suggest a non-metastatic polyneuropathy associated with Hodgkin's disease, and similar cases, predominantly in adult patients, have been reported. This case emphasizes the occurrence of a paraneoplastic syndrome in children, though such syndromes appear to be rare compared with adults.

journal_name

Dev Med Child Neurol

authors

Kurczynski TW,Choudhury AA,Horwitz SJ,Roessmann U,Gross S

doi

10.1111/j.1469-8749.1980.tb04329.x

subject

Has Abstract

pub_date

1980-04-01 00:00:00

pages

205-22

issue

2

eissn

0012-1622

issn

1469-8749

journal_volume

22

pub_type

杂志文章
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    pub_type: 杂志文章,多中心研究

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