Fatigue, level of everyday physical activity and quality of life after liver transplantation.

Abstract:

OBJECTIVE:To assess whether liver transplant recipients have a hypoactive (sedentary) lifestyle and whether the level of everyday physical activity is related to complaints of fatigue. In addition, we explored the relationship between activity level and health-related quality of life. DESIGN:Case comparison. SUBJECTS:Eight persons 6-36 months after liver transplantation with varying severity of fatigue and 8 persons without known impairments (matched for gender, age, social situation and employment). METHODS:Activity levels were assessed during 2 randomly selected consecutive weekdays with an accelerometry-based Activity Monitor. In the transplantation group, severity of fatigue (Fatigue Severity Scale) and health-related quality of life (RAND-36) were also assessed. RESULTS:Five liver transplant recipients had a hypoactive lifestyle, but there was no significant difference in activity level between the transplantation group and comparison group. Severity of fatigue was correlated (p=0.01) with both duration of dynamic activities and intensity of everyday activity (r(s)=-0.81 and -0.84, respectively). Activity level was correlated (p< or =0.05) with several domains of health-related quality of life (r(s)=0.72-0.78). CONCLUSION:As a group, liver transplant recipients were not significantly less active than comparison subjects. Activity level was related with severity of fatigue and health-related quality of life. These findings have implications for the development of interventions needed to rehabilitate persons after liver transplantation.

journal_name

J Rehabil Med

authors

van den Berg-Emons R,Kazemier G,van Ginneken B,Nieuwenhuijsen C,Tilanus H,Stam H

doi

10.1080/16501970500338771

subject

Has Abstract

pub_date

2006-03-01 00:00:00

pages

124-9

issue

2

eissn

1650-1977

issn

1651-2081

pii

L0173950012R1338

journal_volume

38

pub_type

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