Choice of treatments for small hepatocellular carcinoma: hepatectomy, embolization or ethanol injection.

Abstract:

:The results of hepatectomy, percutaneous ethanol injection therapy and transcatheter arterial embolization for small hepatocellular carcinoma (HCC) of 3 cm or less in diameter from the published literature were compared with the authors' experiences with surgical treatment. The survival rates for those treated by hepatectomy and ethanol injection were almost the same, being more than 90% at 1 year and 70% at 3 years. The overall results achieved by embolization were inferior to those achieved by the other two therapeutic modalities, although the 1 year survival rate was not worse. The cancer-free survival rates after hepatectomy and ethanol injection were also similar. Most of the patients with small HCC had associated liver cirrhosis or chronic active hepatitis, but the degree of liver dysfunction and the level of hepatic reserve varied. Anatomically, the number, size, and location of the cancer also varies. Choice of treatment for small HCC should be made based upon the degree of liver function and the anatomic status of the cancer. For example, a patient with multiple (more than four) cancer nodules is a good candidate for embolization. Ethanol injection is indicated for a small HCC, deeply seated in a severely diseased liver. Hepatectomy is the first choice for a small HCC situated near the surface of a liver with relatively good liver function.

authors

Yamasaki S,Hasegawa H,Makuuchi M,Takayama T,Kosuge T,Shimada K

doi

10.1111/j.1440-1746.1991.tb00879.x

subject

Has Abstract

pub_date

1991-07-01 00:00:00

pages

408-13

issue

4

eissn

0815-9319

issn

1440-1746

journal_volume

6

pub_type

杂志文章
  • Post-infectious irritable bowel syndrome in patients with Shigella infection.

    abstract:BACKGROUND AND AIMS:Bacterial gastroenteritis has been known as a risk factor of irritable bowel syndrome (IBS). Several risk factors of post-infectious IBS (PI-IBS) have been documented. The aims of this study were to verify the role of bacterial gastroenteritis in the development of IBS and the risk factors for the d...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2005.03574.x

    authors: Ji S,Park H,Lee D,Song YK,Choi JP,Lee SI

    更新日期:2005-03-01 00:00:00

  • Amount of Helicobacter pylori in gastric mucus during anti-H. pylori treatment.

    abstract::Helicobacter pylori is present in infected patients not only on the gastric epithelial cell surface but also in gastric mucus. We developed a competitive polymerase chain reaction (cPCR) method for quantitative measurement of H. pylori in gastric mucus. The aim of this study was to determine the number of H. pylori in...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1440-1746.1998.tb00678.x

    authors: Furuta T,Takashima M,Futami H,Arai H,Hanai H,Kaneko E

    更新日期:1998-05-01 00:00:00

  • Relationship between Helicobacter pylori hopQ genotype and clinical outcome in Asian and Western populations.

    abstract:BACKGROUND AND AIMS:Outer membrane proteins of Helicobacter pylori mediate important pathogen-host interactions such as colonization, adhesion and the inflammatory response. hopQ genotypes have been suggested to be associated with increased risk of peptic ulcer. The aim of this study was to test the relation of hopQ ge...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2008.05762.x

    authors: Ohno T,Sugimoto M,Nagashima A,Ogiwara H,Vilaichone RK,Mahachai V,Graham DY,Yamaoka Y

    更新日期:2009-03-01 00:00:00

  • Gene profile in the spleen under massive partial hepatectomy using complementary DNA microarray and pathway analysis.

    abstract:BACKGROUND AND AIM:In general, the spleen is one of the abdominal organs connected by the portal system, and a splenectomy improves hepatic functions in the settings of partial hepatectomy (Hx) for portal hypertensive cases or living donor liver transplantation with excessive portal vein flow. Those precise mechanisms ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12573

    authors: Arakawa Y,Shimada M,Utsunomiya T,Imura S,Morine Y,Ikemoto T,Mori H,Kanamoto M,Iwahashi S,Saito Y,Takasu C

    更新日期:2014-08-01 00:00:00

  • Gilbert's syndrome and the risk of death: a population-based cohort study.

    abstract:BACKGROUND AND AIMS:Gilbert's syndrome is a common familial hyperbilirubinemia that may reduce the risk of various age-related diseases because of the antioxidant properties of bilirubin. We conducted a large cohort study using The Health Improvement Network primary care database and compared all-cause mortality rates ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12279

    authors: Horsfall LJ,Nazareth I,Pereira SP,Petersen I

    更新日期:2013-10-01 00:00:00

  • Pertussis toxin-induced redistribution of cortical actomyosin and inhibition of phagocytosis in rat Kupffer cells.

    abstract::The mechanism of phagocytosis by Kupffer cells has been shown to be related to the Ca(2+)-calmodulin and the actomyosin systems. However the role of the transmembrane signal transmitter, G-protein, is still unknown. In this study, a quantitative evaluation of phagocytosis by Kupffer cells of rats in culture and the ef...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1993.tb01526.x

    authors: Hirose M,Watanabe S,Ueno T,Kitami N,Sato N

    更新日期:1993-07-01 00:00:00

  • Distribution of liver stiffness in non-alcoholic fatty liver disease with higher fibrosis-4 index than low cut-off index.

    abstract:BACKGROUND AND AIM:In the condition of high prevalence of non-alcoholic fatty liver disease (NAFLD), a new diagnostic algorithm to efficiently identify NAFLD patients with significant fibrosis is urgently required. We evaluated the predictive ability of the fibrosis-4 index (FIB-4 index) for significant liver fibrosis ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.14559

    authors: Tomeno W,Imajo K,Kuwada Y,Ogawa Y,Kikuchi M,Honda Y,Kato T,Kessoku T,Kirikoshi H,Yoneda M,Kitahora T,Saito S,Ozawa Y,Nakajima A

    更新日期:2019-08-01 00:00:00

  • Efficacy of ursodeoxycholic acid in the treatment of patients with chronic hepatitis C.

    abstract::A case-control study was conducted to evaluate the efficacy of ursodeoxycholic acid (UDCA) in the treatment of Chinese patients with chronic hepatitis C. Patients who failed to have sustained responses to interferon (IFN) therapy, refused to take IFN or were unsuitable for IFN treatment were enrolled into this study. ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1440-1746.1995.tb01596.x

    authors: Lu CL,Chan CY,Hwang SJ,Lu RH,Lee SD

    更新日期:1995-07-01 00:00:00

  • Increased esophageal mucosal/submucosal blood flow in patients with gastroesophageal reflux disease: normalization by treatment with a proton pump inhibitor.

    abstract:BACKGROUND AND AIM:Mucosal injury caused by gastroesophageal reflux may result in changes in esophageal mucosal blood flow. Little is known about esophageal mucosal blood flow in patients with gastroesophageal reflux disease (GERD). Here we examined esophageal mucosal blood flow and the effects of treatment in patients...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2007.05113.x

    authors: Mine S,Iida T,Tabata T,Okada Y,Tanaka Y

    更新日期:2008-02-01 00:00:00

  • Gallbladder cancer: can newer insights improve the outcome?

    abstract::Gallbladder cancer (GBC) is the leading cause of cancer related mortality in certain geographic areas. Most of the patients with GBC have advanced disease at presentation, precluding curative resection resulting in a dismal prognosis. However, recent advances in the understanding of its epidemiology and pathogenesis c...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1746.2011.07048.x

    authors: Dutta U

    更新日期:2012-04-01 00:00:00

  • Herpes simplex esophagitis from 1307 autopsy cases.

    abstract:BACKGROUND AND AIMS:The aim of the present study was to clarify relationship between macroscopic and microscopic features of herpes simplex esophagitis (HSE), and localization of herpes simplex virus type 1 (HSV-1)-infected cells in esophageal lesions from autopsy cases of histopathologically proven HSE. METHODS:The s...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2003.03166.x

    authors: Itoh T,Takahashi T,Kusaka K,Kawaura K,Nakagawa Y,Yamakawa J,Kanda T

    更新日期:2003-12-01 00:00:00

  • Ultrasound-guided fine needle aspiration biopsy of portal vein thrombosis in liver cirrhosis: results in 15 patients.

    abstract::Between 1988 and 1992 ultrasound-guided fine needle aspiration biopsies of thromboses in the main branches of the portal vein were carried out in 15 patients with liver cirrhosis. The aims of the study were to evaluate the usefulness, feasibility and diagnostic accuracy of this procedure in cirrhotics with known or su...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1995.tb01367.x

    authors: De Sio I,Castellano L,Calandra M,Romano M,Persico M,Del Vecchio-Blanco C

    更新日期:1995-11-01 00:00:00

  • Dietary practices and FODMAPs in South Asia: Applicability of the low FODMAP diet to patients with irritable bowel syndrome.

    abstract::The low Fermentable Oligosaccharides, Disaccharides, and Monosaccharides And Polyols (FODMAP) diet has been described, evaluated, and found efficacious for the treatment of patients with irritable bowel syndrome primarily in Western countries. The aim of this review was to address the applicability of this diet to Sou...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/jgh.13885

    authors: Hewawasam SP,Iacovou M,Muir JG,Gibson PR

    更新日期:2018-02-01 00:00:00

  • Intrahepatic interleukin-17+ T cells and FoxP3+ regulatory T cells cooperate to promote development and affect the prognosis of hepatocellular carcinoma.

    abstract:BACKGROUND AND AIM:Recent studies have shown that imbalance between tumor-infiltrating interleukin (IL)-17(+) T cells and regulatory T cells (Tregs) is an important regulator of progression in various cancers, but little is known regarding this imbalance in hepatocellular carcinoma (HCC). This study explored the role o...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12418

    authors: Huang Y,Wang F,Wang Y,Zhu Z,Gao Y,Ma Z,Xu R,Du Z

    更新日期:2014-04-01 00:00:00

  • Hepatitis B virus infection in dialysis patients.

    abstract::Hepatitis B virus (HBV) infection remains a major issue among dialysis patients. It is associated with a high risk of hepatic complication. The liver disease runs a unique clinical course in dialysis patients, as it can progress with modest hepatic inflammation and prominent fibrosis. The conventional cut-off level of...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1746.2005.03837.x

    authors: Wong PN,Fung TT,Mak SK,Lo KY,Tong GM,Wong Y,Loo CK,Lam EK,Wong AK

    更新日期:2005-11-01 00:00:00

  • Implications of culture positivity in acute pancreatitis: does the source matter?

    abstract:BACKGROUND AND AIMS:Sepsis is an important complication and cause of morbidity and mortality in acute pancreatitis (AP). The source of sepsis may be infected pancreatic and peripancreatic collections and/or necrosis or extrapancreatic including infections in the bloodstream or respiratory and urinary tracts. We studied...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12161

    authors: Rao C,Bhasin DK,Rana SS,Gupta R,Gautam V,Singh K

    更新日期:2013-05-01 00:00:00

  • Inducible nitric oxide synthase activity induced by sodium chloride solution prolongs luminal pH elevation in rat and mouse stomachs.

    abstract:BACKGROUND:Sodium chloride (NaCl) is a strong promoter of gastric cancer. We hypothesized that inducible nitric oxide synthase (iNOS) induced by NaCl may be involved in its promoting effects. We investigated iNOS expression by hypertonic NaCl solutions and its pathophysiological roles in the gastric mucosa of rats and ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2003.03130.x

    authors: Tatemichi M,Ogura T,Sakurazawa N,Nagata H,Sugita M,Esumi H

    更新日期:2003-09-01 00:00:00

  • Troglitazone prevents fatty changes of the liver in obese diabetic rats.

    abstract:BACKGROUND AND AIMS:Troglitazone is a newly developed antidiabetic drug and is indicated to be useful for the treatment of patients with type II diabetes mellitus. Recently, however, it became clear that troglitazone could cause liver dysfunction in some patients. In addition, a relationship between the activation of t...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2000.02316.x

    authors: Jia DM,Tabaru A,Akiyama T,Abe S,Otsuki M

    更新日期:2000-10-01 00:00:00

  • High, but not low, dietary retinoids aggravate manifestation of rat liver fibrosis.

    abstract:BACKGROUND:Although there is strong implication that retinoids regulate Ito cell proliferation and collagen synthesis, results from in vivo studies on the relationship between vitamin A and liver fibrosis are conflicting. The present study focuses on the role of vitamin A in carbon tetrachloride (CCl4)-induced fibrosis...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2002.02804.x

    authors: Vollmar B,Heckmann C,Richter S,Menger MD

    更新日期:2002-07-01 00:00:00

  • Hepatobiliary tuberculosis.

    abstract::Tuberculosis is known to involve the liver in different ways. The term hepatobiliary tuberculosis refers to the localized form of hepatic tuberculosis as a distinct clinical entity, with signs and symptoms related to the hepatobiliary tract. Its clinical features and the different diagnostic aids used in its diagnosis...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1746.1998.tb00743.x

    authors: Alvarez SZ

    更新日期:1998-08-01 00:00:00

  • Association of celiac disease with non-cirrhotic portal fibrosis.

    abstract::Both celiac disease and non-cirrhotic portal fibrosis are known to be associated with various autoimmune diseases and have numerous immunological abnormalities. Herein two patients with celiac disease having associated non-cirrhotic portal fibrosis are reported. An autoimmune link between the two conditions is likely ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2006.03296.x

    authors: Sharma BC,Bhasin DK,Nada R

    更新日期:2006-01-01 00:00:00

  • Persistent ileitis after ileal salvage from a failed Kock pouch.

    abstract::A case of persistent ileitis following the refashioning of a Kock ileal pouch into a Brooke ileostomy for severe pouchitis is reported. Preserving the terminal ileum by a salvage procedure may not be a safe alternative to pouch excision with the formation of a new end ileostomy in the surgical management of pouchitis ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1992.tb00999.x

    authors: de Silva HJ,Mortensen NJ

    更新日期:1992-07-01 00:00:00

  • New diagnostic criteria for nutcracker esophagus using conventional water-perfused manometry: a comparison between nutcracker esophagus with and without gastroesophageal reflux disease.

    abstract:BACKGROUND AND AIM:Controversy continues as to whether nutcracker esophagus (NE) is a 'real' manometric disease due to its poor correlation with clinical symptoms such as chest pain or dysphagia. While new NE criteria were proposed in a recent study, that study included NE patients both with and without gastroesophagea...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2010.06301.x

    authors: Jung KW,Jung HY,Yoon IJ,Kim DH,Chung JW,Oh HC,Choi KS,Choi KD,Song HJ,Lee GH,Kim JH

    更新日期:2010-07-01 00:00:00

  • Relationship between Helicobacter pylori infection and gastric metaplasia in the duodenal bulb in the pathogenesis of duodenal ulcer.

    abstract:BACKGROUND:The aim of this study was to determine whether the amount of Helicobacter pylori and the extent of gastric metaplasia in the duodenal mucosa play critical roles in the pathogenesis of duodenal ulcer. METHODS:Duodenal and gastric biopsy specimens were obtained from H. pylori-positive patients with duodenal u...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.1999.01824.x

    authors: Futami H,Takashima M,Furuta T,Hanai H,Kaneko E

    更新日期:1999-02-01 00:00:00

  • Achalasia of the oesophagus: treatments with pneumatic dilatation.

    abstract::A series of 51 patients with achalasia of the oesophagus treated by pneumatic dilatation between 1980 and 1988 is reported. Treatment was assessed as effective (no or minimal dysphagia) in 78% of patients, followed for a mean of 30 months. Thirty-four patients required only one dilatation and only two patients had mor...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1990.tb01125.x

    authors: Prewett EJ,Desmond PV,Breen KJ

    更新日期:1990-11-01 00:00:00

  • Serum levels of transforming growth factor beta1 are significantly correlated with venous invasion in patients with gastric cancer.

    abstract:BACKGROUND AND AIM:The significance of serum levels of transforming growth factor (TGF)-beta1 in the development of gastric cancer is unclear. The purpose of this study is to determine whether serum TGF-beta1 correlated with the clinicopathological findings of patients with gastric cancer. METHODS:Transforming growth ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2005.03939.x

    authors: Lin Y,Kikuchi S,Obata Y,Yagyu K,Tokyo Research Group on Prevention of Gastric Cancer.

    更新日期:2006-02-01 00:00:00

  • Antiviral efficacy of lamivudine versus entecavir in patients with hepatitis B virus-related advanced hepatocellular carcinoma.

    abstract:BACKGROUND AND AIM:Little information is available about the antiviral efficacy of lamivudine (LAM) and entecavir (ETV) in patients with hepatitis B virus (HBV)-related advanced hepatocellular carcinoma (HCC). Thus, we compared the antiviral efficacy of LAM and ETV in these patients. METHODS:The medical records of 134...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2012.07145.x

    authors: Shin HS,Kim SU,Park JY,Kim DY,Han KH,Chon CY,Baatarkhuu O,Ahn SH

    更新日期:2012-09-01 00:00:00

  • Treatment with infliximab for pediatric Crohn's disease: Nationwide survey of Japan.

    abstract:BACKGROUND AND AIM:Childhood-onset inflammatory bowel disease (IBD) is characterized by extensive intestinal involvement and rapid early progression. Infliximab (IFX), cyclosporin (CYA), and tacrolimus (FK506) are increasingly used to treat pediatric IBD; however, their long-term effects and adverse events have not bee...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.13498

    authors: Hosoi K,Ohtsuka Y,Fujii T,Kudo T,Matsunaga N,Tomomasa T,Tajiri H,Kunisaki R,Ishige T,Yamada H,Arai K,Yoden A,Ushijima K,Aomatsu T,Nagata S,Uchida K,Takeuchi K,Shimizu T

    更新日期:2017-01-01 00:00:00

  • Distal colonic neoplasms predict proximal neoplasia in average-risk, asymptomatic subjects.

    abstract::Flexible sigmoidoscopy has been recommended as a screening method to reduce the incidence of colorectal cancer in asymptomatic, average-risk subjects through the early detection and removal of polyps. However, the association between distal and proximal colonic neoplasia and, hence, the requirement for colonoscopic fo...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.1999.01804.x

    authors: Collett JA,Platell C,Fletcher DR,Aquilia S,Olynyk JK

    更新日期:1999-01-01 00:00:00

  • Angiopoietin-2 levels in the hepatic vein as a useful predictor of tumor invasiveness and prognosis in human hepatocellular carcinoma.

    abstract:BACKGROUND AND AIM:Hepatocellular carcinoma (HCC) is characteristically a hypervascular tumor and its progression is known to be closely related to angiogenesis. In this study, we investigated angiopoietin-2 (Ang-2) and vascular endothelial growth factor (VEGF) levels in the hepatic vein draining from HCC, as well as i...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2007.05175.x

    authors: Kuboki S,Shimizu H,Mitsuhashi N,Kusashio K,Kimura F,Yoshidome H,Ohtsuka M,Kato A,Yoshitomi H,Miyazaki M

    更新日期:2008-07-01 00:00:00