Gene profile in the spleen under massive partial hepatectomy using complementary DNA microarray and pathway analysis.

abstract：BACKGROUND AND AIMS:Significant changes in hepatic haemodynamics occur after major hepatectomy, but the pathogenesis of this phenomenon is unclear. This study investigates the serum profile of prostaglandin and nitric oxide in the hepatic and systemic circulation before and after hepatectomy and the temporal relationsh...

journal_title：Journal of gastroenterology and hepatology

authors： Lai OF,Chow PK,Tan S,Song IC,Soo KC,Aw SE,Yu WK,Fook-Chong SM,Satchithanantham S,Chan ST

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND AND AIM:Chronic alcoholic liver disease is associated with hepatic insulin resistance, dysregulated lipid metabolism with increased toxic lipid (ceramide) accumulation, lipid peroxidation, and oxidative and endoplasmic reticulum (ER) stress. Peroxisome-proliferator activated receptor (PPAR) agonists are insu...

journal_title：Journal of gastroenterology and hepatology

authors： Ramirez T,Tong M,Chen WC,Nguyen QG,Wands JR,de la Monte SM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal endoscopic submucosal dissection (ESD) is used for the treatment of large colorectal superficial neoplasms. However, there have been no large studies on electrocoagulation syndrome developing after colorectal ESD. The aim of this study was to clarify the incidence and clinical risk factors...

journal_title：Journal of gastroenterology and hepatology

authors： Ito S,Hotta K,Imai K,Yamaguchi Y,Kishida Y,Takizawa K,Kakushima N,Tanaka M,Kawata N,Yoshida M,Ishiwatari H,Matsubayashi H,Ono H

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Direct-acting antivirals (DAAs) rapidly clear hepatitis C virus (HCV), but the lipid dynamics after DAA treatment remain unknown. Low-density lipoprotein (LDL) cholesterolemia is the predicting factor for the onset and death of atherosclerotic cardiovascular diseases. Thus, in this study, we examined the fre...

journal_title：Journal of gastroenterology and hepatology

authors： Morihara D,Ko YL,Shibata K,Yamauchi R,Fukuda H,Tsuchiya N,Fukunaga A,Kunimoto H,Iwashita H,Takata K,Tanaka T,Sakurai K,Inomata S,Yokoyama K,Nishizawa S,Takeyama Y,Irie M,Shakado S,Sohda T,Sakisaka S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND AND AIM:Although sporadic non-ampullary duodenal adenoma is speculated to be precancerous lesion, the relationship between adenoma and carcinoma remains unclear due to their rarity. Previous studies on sporadic non-ampullary duodenal epithelial neoplasm (SNADEN) have mainly targeted superficial tumors, like ...

journal_title：Journal of gastroenterology and hepatology

authors： Matsueda K,Kanzaki H,Matsueda K,Nasu J,Yoshioka M,Nakagawa M,Inoue M,Inaba T,Imagawa A,Takatani M,Takenaka R,Suzuki S,Tomoda J,Yagi T,Fujiwara T,Tanaka T,Okada H

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Liver stiffness (LS), measured by transient elastography, has been validated as a non-invasive surrogate for liver fibrosis. METHODS:We investigated the long-term predictive ability of LS for hepatocellular carcinoma (HCC) development and overall survival in 1146 patients with chronic hepatitis C by...

journal_title：Journal of gastroenterology and hepatology

authors： Nakagomi R,Tateishi R,Masuzaki R,Soroida Y,Iwai T,Kondo M,Fujiwara N,Sato M,Minami T,Uchino K,Enooku K,Nakagawa H,Asaoka Y,Kondo Y,Tanaka Y,Otsuka M,Kato N,Moriya K,Ikeda H,Koike K

更新日期：2019-05-01 00:00:00

abstract：:We examined whether a single inoculation of Helicobacter pylori can colonize the stomachs of ulcerated rats and delay their healing and whether an antibiotic drug and acid pump inhibitors can enhance the ulcer healing in infected rats. Ulcers were produced by a submucosal injection of acetic acid solution into the gas...

journal_title：Journal of gastroenterology and hepatology

authors： Li T,Okabe S

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatorenal syndrome (HRS) occurs in patients with advanced liver cirrhosis and has a poor outcome. The aim of the present study was to investigate which patients with HRS are likely to benefit from hemodialysis. METHODS:Data were collected prospectively from 30 patients with Child-Pugh C liver cirr...

journal_title：Journal of gastroenterology and hepatology

authors： Witzke O,Baumann M,Patschan D,Patschan S,Mitchell A,Treichel U,Gerken G,Philipp T,Kribben A

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known whether routine prophylaxis against Pneumocystis jirovecii pneumonia (PJP) is needed in patients with inflammatory bowel disease (IBD) on immunosuppression, especially in Asian populations. We, therefore, sought to investigate the incidence and risk factors of PJP in patients with IBD...

journal_title：Journal of gastroenterology and hepatology

authors： Nam K,Park SH,Lee J,Jo S,Kim SO,Noh S,Park JC,Kim JY,Kim J,Ham NS,Oh EH,Song EM,Hwang SW,Yang DH,Ye BD,Byeon JS,Myung SJ,Yang SK

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate the relationship between human leptin receptor (LEPR) gene G3057A polymorphism and type 2 diabetes mellitus (T2DM) patients complicated with or without non-alcoholic fatty liver disease (NAFLD). METHODS:Two hundred and sixteen cases of newly diagnosed T2DM patients (104 cases complica...

journal_title：Journal of gastroenterology and hepatology

authors： Lu H,Sun J,Sun L,Shu X,Xu Y,Xie D

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIM:Terlipressin has been shown to be effective in the management of hepatorenal syndrome. However, how terlipressin exerts its effect on the renal artery is unknown. The aim of the present study was to assess the effects of terlipressin on systemic, hepatic and renal hemodynamics in cirrhosis. METHODS:...

journal_title：Journal of gastroenterology and hepatology

authors： Narahara Y,Kanazawa H,Taki Y,Kimura Y,Atsukawa M,Katakura T,Kidokoro H,Harimoto H,Fukuda T,Matsushita Y,Nakatsuka K,Sakamoto C

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The (13)C-urea breath test ((13)C-UBT) is a reliable non-invasive method of diagnosing Helicobacter pylori infection in adults and children. However, only a few validation studies have been performed on the (13)C-UBT in very young children. The purpose of the present study was to evaluate the diagno...

journal_title：Journal of gastroenterology and hepatology

authors： Yang HR,Seo JK

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND AIM:Mucosal traction as a "second hand" in endoscopic submucosal dissection (ESD) is very helpful for ESD operators. The efficacy of using a snare combined with endoclips to assist in ESD (SC-ESD) was evaluated whether it could achieve peroral external traction (PET) and peroral internal traction (PIT) a...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang Q,Yao X,Cai JQ,Zhang BH,Wang Z

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND AIM:Liver stiffness measurement (LSM) with transient elastography is a non-invasive and reliable test for liver fibrosis. However a small proportion of patients may have unreliable LSM or LSM failure. The aim of the present study was to investigate the factors associated with unreliable LSM or LSM failur...

journal_title：Journal of gastroenterology and hepatology

authors： Wong GL,Wong VW,Chim AM,Yiu KK,Chu SH,Li MK,Chan HL

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND AIM:The present study was aimed to evaluate the hepatic zonation of multidrug resistance-associated protein 2 (mrp2), an important drug transporter, and its potential changes during the induction of its expression by known inducer, dexamethasone (DEX). METHODS:The hepatic expression of mrp2 was studied ...

journal_title：Journal of gastroenterology and hepatology

authors： Micuda S,Fuksa L,Brcakova E,Osterreicher J,Cermanova J,Cibicek N,Mokry J,Staud F,Martinkova J

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Disorders of the motor function of the upper gastrointestinal tract have been implicated in the pathogenesis of non-ulcer dyspepsia. Approximately 50% of patients with abdominal symptoms (without ulcer) have normal gastric emptying. Apart from gastric emptying, other mechanisms are very important in the etio...

journal_title：Journal of gastroenterology and hepatology

authors： Mizushima T,Sawa K,Ochi K,Tanioka H,Wakuta A,Matsushita K,Shirahige A,Kiura K,Tanimoto M,Koide N,Harada H

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of the present study was to clarify relationship between macroscopic and microscopic features of herpes simplex esophagitis (HSE), and localization of herpes simplex virus type 1 (HSV-1)-infected cells in esophageal lesions from autopsy cases of histopathologically proven HSE. METHODS:The s...

journal_title：Journal of gastroenterology and hepatology

authors： Itoh T,Takahashi T,Kusaka K,Kawaura K,Nakagawa Y,Yamakawa J,Kanda T

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND AIM:Abdominal wall hernia is a common feature of decompensated liver cirrhosis and frequently causes life-threatening complications or severe pain. However, there have been no data reported on postoperative mortality, hepatic functional deterioration and recurrence rate according to Child-Turcotte-Pugh (...

journal_title：Journal of gastroenterology and hepatology

authors： Park JK,Lee SH,Yoon WJ,Lee JK,Park SC,Park BJ,Jung YJ,Kim BG,Yoon JH,Kim CY,Ha J,Park KJ,Kim YJ

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Bacterial gastroenteritis has been known as a risk factor of irritable bowel syndrome (IBS). Several risk factors of post-infectious IBS (PI-IBS) have been documented. The aims of this study were to verify the role of bacterial gastroenteritis in the development of IBS and the risk factors for the d...

journal_title：Journal of gastroenterology and hepatology

authors： Ji S,Park H,Lee D,Song YK,Choi JP,Lee SI

更新日期：2005-03-01 00:00:00

abstract：:Autoimmune hepatitis (AIH) is an inflammatory liver disease with diverse clinical spectrum, which predominantly affects females. This review provides detailed comparisons of epidemiology, genetic predispositions, clinical features, risk factors of hepatocellular carcinoma, and mortality in AIH patients between eastern...

journal_title：Journal of gastroenterology and hepatology

authors： Yang F,Wang Q,Bian Z,Ren LL,Jia J,Ma X

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Sodium chloride (NaCl) is a strong promoter of gastric cancer. We hypothesized that inducible nitric oxide synthase (iNOS) induced by NaCl may be involved in its promoting effects. We investigated iNOS expression by hypertonic NaCl solutions and its pathophysiological roles in the gastric mucosa of rats and ...

journal_title：Journal of gastroenterology and hepatology

authors： Tatemichi M,Ogura T,Sakurazawa N,Nagata H,Sugita M,Esumi H

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND AND AIM:The high-mobility group box 1 (HMGB1) protein plays an important role in a lot of biological behaviors, including DNA damage repair, gene transcription, cell replication, and cell death, and its expression is higher in many solid tumors tissues than in their adjacent normal tissues, and it is always ...

journal_title：Journal of gastroenterology and hepatology

authors： Di X,He G,Chen H,Zhu C,Qin Q,Yan J,Zhang X,Sun X

更新日期：2019-04-01 00:00:00

abstract：:Although the advancement of molecular oncology in gastric cancer lags behind that of colorectal cancer, the rapid developments witnessed in recent years have improved our understanding of the carcinogenesis, aetiology, progression and metastasis of gastric cancer. The different molecular genetic alterations in intesti...

journal_title：Journal of gastroenterology and hepatology

authors： Chan AO,Luk JM,Hui WM,Lam SK

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND AIM:To present the experience in management of inflammatory liver pseudotumors from a specialist surgical unit and to review the medical literature on this rare manifestation. METHODS:Between 1995 and 2008, four patients were identified with this type of tumor from a total of 108 resected benign liver l...

journal_title：Journal of gastroenterology and hepatology

authors： Milias K,Madhavan KK,Bellamy C,Garden OJ,Parks RW

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND AIM:Pancreatic pseudocyst is a common complication of chronic pancreatitis. The identification of risk factors and development of a nomogram for pancreatic pseudocysts in chronic pancreatitis patients may contribute to the early diagnosis and intervention of pancreatic pseudocysts. METHODS:Patients with...

journal_title：Journal of gastroenterology and hepatology

authors： Hao L,Pan J,Wang D,Bi YW,Ji JT,Xin L,Liao Z,Du TT,Lin JH,Zhang D,Zeng XP,Ye B,Zou WB,Chen H,Xie T,Li BR,Zheng ZH,Hu LH,Li ZS

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND AND AIM:Non-alcoholic fatty liver disease is the result of an imbalance in hepatic lipid partitioning that favors fatty acid synthesis and storage over fatty acid oxidation and triglyceride secretion. The progressive, inflammatory disorder of steatohepatitis can be prevented or reversed by correcting this li...

journal_title：Journal of gastroenterology and hepatology

authors： Larter CZ,Yeh MM,Cheng J,Williams J,Brown S,dela Pena A,Bell-Anderson KS,Farrell GC

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND AIM:Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that plays a significant role in tumor development. SPARC has been indicated that promotes tumorigenesis, metastasis, and poor prognosis in prostate cancer and lung cancer. Therefore, we sought to investigate the mol...

journal_title：Journal of gastroenterology and hepatology

authors： Jiang X,Liu F,Wang Y,Gao J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIMS:A few cases are reported of liver neoplasms observed in patients with glycogen storage disease type 1a (GSD1a). Genetic analysis was carried out in adult Japanese patients with GSD1a and their family members, and hepatic tumors were also investigated in these patients. METHODS:DNA was extracted fro...

journal_title：Journal of gastroenterology and hepatology

authors： Nakamura T,Ozawa T,Kawasaki T,Nakamura H,Sugimura H

更新日期：2001-12-01 00:00:00

abstract：:Advances in technology have made possible the clinical application of magnetic resonance cholangiography, endoscopic, intra-operative and laparoscopic ultrasound in the study of the biliary tree, in addition to conventional magnetic resonance imaging and transabdominal ultrasound. The role of the conventional, as well...

journal_title：Journal of gastroenterology and hepatology

authors： Chan YL

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00