Estrogen improves psychological function in asymptomatic postmenopausal women.

Abstract:

:Estrogen treatment of postmenopausal women has been suggested to improve mood and psychological function. However, this remains controversial because previous studies involved heterogeneous groups, were not double blind, and included women who were also experiencing somatic symptoms that were relieved by estrogen. A randomized double-blind study was carried out comparing the effects of placebo and conjugated equine estrogens (0.625 and 1.25 mg) on psychological function over 3 months in 36 asymptomatic women, aged 45-60. The tests included the Minnesota Multiphasic Personality Inventory-168, the Profile of Adaptation to Life, and the Beck Depression Inventory. Memory was assessed directly by the Wechsler Adult Intelligence Scales, measuring both digit span and digit symbol. All women were well-adjusted psychologically. The income management scale of the Profile of Adaptation to Life improved (P less than .05) with estrogen, as did the Beck Depression Inventory (P less than .05), but these results were not dose-related. Memory assessed prospectively by the Wechsler Adult Intelligence Scales was not affected significantly. These results suggest that estrogen use may improve the overall quality of life in postmenopausal women.

journal_name

Obstet Gynecol

authors

Ditkoff EC,Crary WG,Cristo M,Lobo RA

subject

Has Abstract

pub_date

1991-12-01 00:00:00

pages

991-5

issue

6

eissn

0029-7844

issn

1873-233X

journal_volume

78

pub_type

临床试验,杂志文章,随机对照试验
  • ACOG practice bulletin: Clinical management guidelines for obstetrician-gynecologists, number 57, November 2004. Gynecologic herpes simplex virus infections.

    abstract::Both herpes simplex virus (HSV) type I and HSV type 2 can cause genital herpes. Because the infection is chronic, genital herpes has become the most common sexually transmitted disease among women. The prevalence of the HSV-2 antibody among women in the United States is 26%, although genital herpes has been diagnosed ...

    journal_title:Obstetrics and gynecology

    pub_type: 指南,杂志文章,实务指引

    doi:

    authors: ACOG Committee on Practice Bulletins--Gynecology.

    更新日期:2004-11-01 00:00:00

  • Fertility-conserving surgery for young women with stage IA1 cervical cancer: safety and access.

    abstract:OBJECTIVE:To estimate the safety of fertility-conserving surgery for stage IA1 cervical cancer and to analyze predictors of access to conization. METHODS:We analyzed women with stage IA1 cervical cancer aged 40 years or younger who were diagnosed between 1988 and 2005 and recorded in the Surveillance, Epidemiology, an...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3181d06b68

    authors: Wright JD,Nathavithrana R,Lewin SN,Sun X,Deutsch I,Burke WM,Herzog TJ

    更新日期:2010-03-01 00:00:00

  • Vaginal prostaglandin E1 analogue (ONO-802) to soften the cervix in first trimester abortion.

    abstract::Cervical softening by vaginal administration of a prostaglandin E1 analogue (ONO-802) was studied in a double-blind, placebo-controlled study using an objective measure of cervical resistance in 121 women undergoing first trimester induced abortion. Three hours after administration, cervical resistance in control and ...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Hulka JF,Chepko M

    更新日期:1987-01-01 00:00:00

  • Diagnosis of a supernumerary ovary with human chorionic gonadotropin.

    abstract::The preoperative diagnosis of ectopic ovarian tissue has been reported only once in the literature. In the present case, differential ovarian and adrenal testing was used to diagnose and aberrant ovarian source of persistently elevated plasma estrogen in a patient who had undergone bilateral oophorectomy and adrenalec...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Kosasa TS,Griffiths CT,Shane JM,Leventhal JM,Naftolin F

    更新日期:1976-02-01 00:00:00

  • A simple test for predicting pregnancy-induced hypertension.

    abstract::One hundred thirty-one nulliparous patients between 28 to 34 weeks' gestation with no known history of renal disease or hypertension were placed in the left lateral recumbent position and their blood pressures were taken once and recorded. They then turned to the supine position where another blood pressure was taken ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Peck TM

    更新日期:1977-11-01 00:00:00

  • Early abdominal incision recurrence in a patient with stage I adenocarcinoma of the endometrium.

    abstract:BACKGROUND:Although most patients with a surgical stage I endometrial cancer have an excellent prognosis, some patients will experience a recurrence. Endometrial cancer typically recurs at the vaginal cuff or in the pelvis; however, it can recur distantly in the abdomen or lung. Although recurrences have been reported ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000123268.57857.0d

    authors: Chen CC,Straughn JM Jr,Kilgore LC

    更新日期:2004-11-01 00:00:00

  • Multigated simultaneous spectral Doppler imaging: a new ultrasound modality.

    abstract:BACKGROUND:Spectral Doppler ultrasound, an important diagnostic tool for the functional assessment of various organs, as yet has no major use in prenatal diagnosis due to the conventional technique's limitation of analyzing only one site at a time. Our aim was to develop a new modality that shows simultaneous studies o...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Haberman S,Friedman Z

    更新日期:1998-08-01 00:00:00

  • Appendectomy in the surgical treatment of endometriosis.

    abstract::To address the question of when to perform an appendectomy in the surgical treatment of endometriosis, a series of 500 consecutive appendectomies was reviewed. In 104 patients with pelvic endometriosis who were undergoing appendectomy, the appendix was a relatively common (13%) extragenital site of endometriosis. Gros...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Pittaway DE

    更新日期:1983-04-01 00:00:00

  • Prediction of preterm delivery in the second trimester.

    abstract:OBJECTIVE:The aim of this study was to estimate the probability of spontaneous delivery at 34 weeks or less according to cervical assessment by transvaginal scan associated with previous obstetric history. METHODS:Ultrasound transvaginal cervical length and presence of funneling were evaluated in 1,958 singleton pregn...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000154157.22500.1d

    authors: de Carvalho MH,Bittar RE,Brizot Mde L,Bicudo C,Zugaib M

    更新日期:2005-03-01 00:00:00

  • Expectant management of twin pregnancies discordant for anencephaly.

    abstract:OBJECTIVE:To study the clinical course and perinatal outcome of twin pregnancies discordant for anencephaly, without selective termination. METHODS:We conducted a descriptive retrospective study of 14 cases of dichorionic twin pregnancies discordant for anencephaly, which were managed expectantly in five Israeli perin...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(95)00309-F

    authors: Lipitz S,Meizner I,Yagel S,Shapiro I,Achiron R,Schiff E

    更新日期:1995-12-01 00:00:00

  • Rhabdomyolysis After Hyperemesis Gravidarum.

    abstract:BACKGROUND:Hyperemesis gravidarum may lead to hypovolemia and substantial electrolyte abnormalities, including hypokalemia. Hypokalemia, when profound, may result in rare consequences, such as rhabdomyolysis. CASE:A 20-year-old woman with hyperemesis gravidarum at 19 weeks of gestation presented with extreme leg weakn...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001418

    authors: Lassey SC,Robinson JN

    更新日期:2016-07-01 00:00:00

  • Influence of Lymphadenectomy on Survival for Early-Stage Endometrial Cancer.

    abstract:OBJECTIVE:To use a number of methods to control for confounding and selection bias to examine the association between lymphadenectomy and survival in a large cohort of women with endometrial cancer. METHODS:A retrospective cohort study using the National Cancer Data Base was performed to identify women with endometrio...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001194

    authors: Wright JD,Huang Y,Burke WM,Tergas AI,Hou JY,Hu JC,Neugut AI,Ananth CV,Hershman DL

    更新日期:2016-01-01 00:00:00

  • Sexual function in women with urinary incontinence and pelvic organ prolapse.

    abstract:OBJECTIVE:To compare sexual function in women with urinary incontinence and pelvic organ prolapse and to determine the effects of therapy on sexual function. METHODS:343 community-dwelling women older than 45 years with urinary incontinence or advanced prolapse were recruited into a multi-armed clinical trial. Women w...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0029-7844(01)01727-6

    authors: Barber MD,Visco AG,Wyman JF,Fantl JA,Bump RC,Continence Program for Women Research Group.

    更新日期:2002-02-01 00:00:00

  • Serum human chorionic somatomammotropin in unaborted hydatidiform mole.

    abstract::Serum human chorionic somatomammotropin (hCS) was measured in 35 patients with intact unaborted hydatidiform mole by a rapid radioimmunoassay using 70% dioxane in water to separate the bound from unbound fraction. Serum hCG was measured by a hemagglutination inhibition method. Serum hCS ranged from 250 to 5900 ng/ml, ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Dawood MY,Teoh ES

    更新日期:1976-02-01 00:00:00

  • Metabolic syndrome as a risk factor for hypertension after preeclampsia.

    abstract:OBJECTIVE:To identify metabolic and obstetric risk factors associated with hypertension after preeclampsia. METHODS:We analyzed demographic and clinical data from a postpartum screening (blood pressure, microalbuminuria and fasting plasma levels of glucose, insulin, and lipid profile) from 683 primiparous women with a...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e31825f21ff

    authors: Spaan JJ,Sep SJ,van Balen VL,Spaanderman ME,Peeters LL

    更新日期:2012-08-01 00:00:00

  • Combination gefitinib and methotrexate compared with methotrexate alone to treat ectopic pregnancy.

    abstract:OBJECTIVE:To determine the safety, tolerability, and efficacy of combination gefitinib and methotrexate to treat ectopic pregnancy. METHODS:We performed a phase I, single-arm (nonrandomized), open-label study. Twelve women with ectopic pregnancies were administered methotrexate (50 mg/m, intramuscular) and 250 mg oral...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3182a14cfb

    authors: Skubisz MM,Horne AW,Johns TG,Nilsson UW,Duncan WC,Wallace EM,Critchley HOD,Tong S

    更新日期:2013-10-01 00:00:00

  • Bleeding pattern and endometrial changes during continuous combined hormone replacement therapy. The Ogen/Provera Study Group.

    abstract:OBJECTIVE:To establish the optimum oral daily dose of micronized medroxyprogesterone acetate, given in combination with a fixed oral dose of estrone (E1) sulfate as hormone replacement therapy, that provides endometrial protection and induces cessation of vaginal bleeding. METHODS:This multicenter, randomized, double-...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0029-7844(98)00038-6

    authors: Nand SL,Webster MA,Baber R,O'Connor V

    更新日期:1998-05-01 00:00:00

  • From Gestational Hypertension and Preeclampsia to Atypical Hemolytic Uremic Syndrome.

    abstract:BACKGROUND:Preeclampsia is a leading cause of morbidity and mortality during pregnancy. The variability of clinical features suggests that preeclampsia is not a single disease. Atypical hemolytic uremic syndrome, resulting from defective regulation of the alternative complement pathway, is less well known and may be mi...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001340

    authors: Tsai HM,Kuo E

    更新日期:2016-05-01 00:00:00

  • Chlorhexidine-alcohol compared with povidone-iodine for surgical-site antisepsis in cesarean deliveries.

    abstract:OBJECTIVE:To estimate the incidence of surgical-site infection with use of chlorhexidine-alcohol compared with povidone-iodine among women undergoing cesarean deliveries. METHODS:This was a retrospective cohort review of 1,000 consecutive cases in women who underwent cesarean delivery over a 1-year interval. The prima...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/aog.0b013e31826f3bd9

    authors: Menderes G,Athar Ali N,Aagaard K,Sangi-Haghpeykar H

    更新日期:2012-11-01 00:00:00

  • Internal Validation of the Sepsis in Obstetrics Score to Identify Risk of Morbidity From Sepsis in Pregnancy.

    abstract:OBJECTIVE:To prospectively validate the Sepsis in Obstetrics Score, a pregnancy-specific sepsis scoring system, to identify risk for intensive care unit (ICU) admission for sepsis in pregnancy. METHODS:This is a prospective validation study of the Sepsis in Obstetrics Score. The primary outcome was admission to the IC...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000002260

    authors: Albright CM,Has P,Rouse DJ,Hughes BL

    更新日期:2017-10-01 00:00:00

  • Serum C-reactive protein and Chlamydia trachomatis antibodies in preterm delivery.

    abstract:OBJECTIVE:To assess the association between Chlamydia trachomatis antibodies, antibodies to C trachomatis heat shock proteins 60 and 10, and C-reactive protein (CRP) levels in maternal serum measured by highly sensitive CRP assay during the first trimester and spontaneous preterm delivery before 37 weeks of gestation. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000164464.11979.5d

    authors: Karinen L,Pouta A,Bloigu A,Koskela P,Paldanius M,Leinonen M,Saikku P,Jêrvelin MR,Hartikainen AL

    更新日期:2005-07-01 00:00:00

  • Cystic ovarian enlargement resulting from autoimmune oophoritis.

    abstract::Autoimmune oophoritis is a rare cause of premature ovarian failure. Previous studies of autoimmune oophoritis have detailed the clinical, immunologic, and histologic findings. The gross pathologic features of the involved ovaries have detailed the clinical, immunologic, and histologic findings. The gross pathologic fe...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Biscotti CV,Hart WR,Lucas JG

    更新日期:1989-09-01 00:00:00

  • Primary peritoneal cancer after bilateral salpingo-oophorectomy in two patients with Lynch syndrome.

    abstract:BACKGROUND:Women with Lynch syndrome or hereditary nonpolyposis colorectal carcinoma (HNPCC) have a 40-60% lifetime risk of endometrial cancer and a 7-12% lifetime risk of ovarian cancer. Risk-reducing surgery, including hysterectomy and bilateral salpingo-oophorectomy (BSO), is currently recommended once child bearing...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3181b6f4f9

    authors: Schmeler KM,Daniels MS,Soliman PT,Broaddus RR,Deavers MT,Vu TM,Chang GJ,Lu KH

    更新日期:2010-02-01 00:00:00

  • Use of recombinant activated factor VII in primary postpartum hemorrhage: the Northern European registry 2000-2004.

    abstract:OBJECTIVE:To collect data from nine European countries for cases of obstetric hemorrhage between 2000 and 2004 in which recombinant activated factor VII (rFVIIa) was used. METHODS:The cases were identified through national surveys. Standardized case report forms included sociodemographic details, past medical and obst...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000288515.48066.99

    authors: Alfirevic Z,Elbourne D,Pavord S,Bolte A,Van Geijn H,Mercier F,Ahonen J,Bremme K,Bødker B,Magnúsdóttir EM,Salvesen K,Prendiville W,Truesdale A,Clemens F,Piercy D,Gyte G

    更新日期:2007-12-01 00:00:00

  • An evaluation of the significance of positive oxytocin challenge test.

    abstract::Sixty-six of 390 patients studied at LAC/USC Women's Hospital between 1970 and 1973 had positive oxytocin challenge tests (OCT). Twenty-four percent of patients who were allowed direct monitored labor after a positive OCT showed no late deceleration and must be assumed to have had false-positive tests. Patients with p...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Freeman RK,Goebelsman UW,Nochimson D,Cetrulo C

    更新日期:1976-01-01 00:00:00

  • Subsequent pregnancies in previously infertile women with endometriosis.

    abstract::Sixty-eight previously infertile patients with endometriosis who had delivered a child tried to conceive again. Fifty-two of them were successful, 28 within 1 year, and 16 were not. The ability to conceive a second child was uniformly good regardless of the stage of the previous disease, the method of treatment, the d...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-198812000-00020

    authors: Rosenfeld DL,Jacob J

    更新日期:1988-12-01 00:00:00

  • High compared with standard gentamicin dosing for chorioamnionitis: a comparison of maternal and fetal serum drug levels.

    abstract:OBJECTIVE:To compare umbilical cord and maternal serum peak gentamicin concentration, gentamicin elimination, and clinical outcomes between women who received once-daily compared with standard, thrice-daily dosing for clinical chorioamnionitis. METHODS:We randomly assigned 38 laboring women, at least 34 weeks gestatio...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.AOG.0000151106.87930.1a

    authors: Locksmith GJ,Chin A,Vu T,Shattuck KE,Hankins GD

    更新日期:2005-03-01 00:00:00

  • Intraabdominal calcification in treated disseminated carcinoma of the ovary.

    abstract::The presence of diffuse abdominal calcification in patients with known carcinoma is usually a sign of metastatic involvement. This finding in some patients who have been treated with high dosage radiation therapy may represent areas of tumor necrosis and subsequent healing without evidence of active malignancy. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Menuck L

    更新日期:1977-01-01 00:00:00

  • Multifetal reduction of triplets and pregnancy outcome.

    abstract::Multifetal pregnancy reduction has been suggested as a strategy to improve pregnancy outcome in grand multiple gestations of three or more fetuses. We prospectively investigated multifetal pregnancy reduction in 13 women with triplet pregnancies in the first trimester following ovulation induction, in vitro fertilizat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Porreco RP,Burke MS,Hendrix ML

    更新日期:1991-09-01 00:00:00

  • Ovarian and extraovarian endometriosis-associated cancer.

    abstract:OBJECTIVE:To determine clinical characteristics of women with endometriosis-associated intraperitoneal cancers, to assess differences based on the relationship of the cancer to the endometriosis, and to assess factors associated with survival. METHODS:A search of medical records at The University of Texas M. D. Anders...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(02)02149-x

    authors: Modesitt SC,Tortolero-Luna G,Robinson JB,Gershenson DM,Wolf JK

    更新日期:2002-10-01 00:00:00