Abstract：
:There have been four major pioneers from Eastern Europe in the neuroscientific study of memory and learning: Pavlov, Bekhterev, Beritashvili and Konorski. The thinking of each evolved with the progress of neuroscientific knowledge throughout the world, and save for Pavlov, each encountered governmental opposition to their views. Among the clues largely overlooked in their examination of conditional reflexes was the fact that the animal appreciates not only its own appetitive state but its immersion in the experimental setting. The latter in itself must require considerable, ongoing neuronal activity to sustain it. There is also the question as to whether "motivation" is an essential feature for the formation of conditional connections; and in cases where it is seemingly absent, as in recognition memory, the processes that underlie the astonishing efficacy of such memory formation remain almost wholly obscure. Finally, it is remarked that the cerebral cortex, as initially supposed, may indeed be the governing locus, even of such simple effects as habituation.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Doty RWsubject
Has Abstractpub_date
2006-01-01 00:00:00pages
91-5; discussion 95-7issue
1eissn
0065-1400issn
1689-0035journal_volume
66pub_type
传,历史文章,杂志文章abstract：:Some aspects of the functional significance of sleep are considered. These involve studies on (i) the dynamics of electrical activity in the neo- and archi-paleocortical structures of the brain in the sleep-wakefulness cycle, (ii) the effect of selective deprivation of different sleep phases on the sleep-wakefulness c...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Abnormal auditory temporal processing might be an underlying deficit in language disabilities. The auditory temporal-order threshold, one measure for temporal processing abilities, is defined as the shortest time interval between two acoustic events necessary for a person to be able to identify the correct temporal or...
journal_title：Acta neurobiologiae experimentalis
pub_type： 临床试验,杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:New multichannel descriptors of EEG activity: complexity (omega), total power (zeta) and generalized frequency (phi) were applied to whole night sleep analysis in 11 healthy subjects. The values of omega and phi decreased systematically from waking to slow wave sleep, and increased systematically in consecutive NREM-R...
journal_title：Acta neurobiologiae experimentalis
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Transcranial magnetic stimulation was carried out in 30 healthy subjects, aged 20 to 55 and 156 to 180 cm tall, in whom cortical excitability threshold was determined for musculus (m.) abductor digiti minimi (ADM) and m. extensor digitorum brevis (EDB). The lowest stimulus intensity causing in the muscle a reproducibl...
journal_title：Acta neurobiologiae experimentalis
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Our work assesses the effects of mu opioid receptor activation on high-threshold Ca2+/Ba2+ currents in freshly dispersed pyramidal neurons of the medial prefrontal cortex in rats. Application of the specific mu receptor agonist (D-Ala2+, N-Me-Phe4+, Gly5+-ol)-enkephalin (DAMGO) at 1 microM decreased Ca2+ current ampli...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:In the context of cell therapy, the epigenetic status of core stemness transcription factor (STF) genes regulating the cell proliferation/differentiation program is of primary interest. Our results confirmed that in vitro differentiation of the umbilicalcord-blood-derived-neural-stem-cells (HUCB-NSC) coincides with th...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:The term reflex is used in its widest sense and denotes the neural processes and effector responses controlled by the evoking stimulus and the feedback stimuli. The reflexes having their specific component facilitated by drive central processes are denoted as higher. Escape, avoidance and approach higher reflexes are ...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：:The purpose of this review is to summarize current knowledge about the gut microbiota in neuropsychiatric disorders. It is estimated that the human gut is colonized by up to 1018 microorganisms, mostly anaerobic bacteria. The gut microbiome is responsible for multiple functions, e.g. tightness of the intestine barrier...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章,评审
doi：
更新日期：2018-01-01 00:00:00
abstract：:It was found previously that unilateral destruction of the ventral tegmental area (VTA) facilitated behavioral responses (exploration, eating) induced by electrical stimulation of the contralateral VTA. The same effect occurred after unilateral injections of pharmacological agents, which led to a decrease in dopaminer...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Leukemia inhibitory factor (LIF) is a neuroprotective cytokine that is necessary for the normal development of astrocytes. Oxygen-glucose deprivation (OGD) can induce astrocyte proliferation by increasing hypoxia-inducible factor alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF). Here, we studied whethe...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:The mechanisms involved in avoidance behavior are discussed. It is assumed that the conditioned stimulus (CS) activates the memory pattern of associations related to the former applications of the unconditioned stimulus (US) and, as a result, produces an undesirable sensory state. This activates another memory pattern...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章,评审
doi：
更新日期：1980-01-01 00:00:00
abstract：:The effects of unilateral ablation of the cortical motor forelimb area on instrumental avoidance responses consisting of lifting the forelimb and holding it within a 4 cm wide "safety zone" were studied in dogs. It was found that the surgery irreversibly impaired the search for the safety zone, while the ability to ma...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:The experiment concerned the functional specialization of brain hemispheres in recognizing faces expressing emotions in patients with focal brain damage of the left and right hemispheres and in persons without damage of the central nervous system. Three types of faces were presented: happy i.e. expressing positive emo...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:This study describes the topography, borders and divisions of the globus pallidus in the Brazilian short-tailed opossum (Monodelphis domestica) and distribution of the three calcium binding proteins, parvalbumin (PV), calbindin D-28k (CB) and calretinin (CR) in that nucleus. The globus pallidus of the opossum consists...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:The effect of anorectic dose of amphetamine on some correlates of arousal (hippocampal EEG and EOG activity) was examined in cats. After injection of amphetamine the frequency of hippocampal rhythmic slow activity and EOG activity increased when preinjection value of rhytmic slow activity was low, but decreased when i...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:In this study we evaluated biochemical blood serum parameters and the association of Cyclin-dependent kinase 5 (CDK5) gene polymorphisms with the risk of Alzheimer's disease (AD) in the Polish population. We observed an elevated total cholesterol, low-density lipoproteins (LDL) and homocysteine levels and lower concen...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:Discrimination learning of instrumental responses to auditory compound stimuli was investigated in opossums using the R-no R (go-no go) differentiation. Each compound stimulus consisted of two factors: quality and location. Each correct response performed to the conditioned positive, or "safe" stimulus, was rewarded b...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Mutations in the PINK1 gene are responsible for typical symptoms of Parkinson's disease. Using Drosophila melanogaster mutant PINK1B9 and after PINK1 silencing with RNAi using transgenic lines, we observed defects in synapses and behavior. The lack or reduced expression of PINK1 prolonged sleep during the day (nap) an...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2018-01-01 00:00:00
abstract：:As investigation has been made of the adequacy of direct current to block conduction in the myelinated fibres of the cervical vagus nerve, leaving the nonmyelinated fibres conducting normally. Conduction was assessed from the compound electroneurograms, and from single fibre recording. Conduction of spontaneous activi...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1973-01-01 00:00:00
abstract：:Working memory is an ability to keep information in short-term memory and manipulate them 'on line'. Working memory is also involved in complex frontal executive functions. The role of dopaminergic system in modulating working memory processes in prefrontal cortex is well established. Also the role of serotoninergic r...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:During luteolysis in sheep, episodic pulses of oxytocin (OT), contributed by the neurohypophysis and the corpus luteum (CL), stimulate uterine luteolytic pulses of prostaglandin (PG) F2 alpha via endometrial OT receptors. To distinguish relative contributions of neurohypophysial and luteal OT, ovariectomized sheep wer...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The pineal hormone melatonin is a potent free radical scavenger. In particular, it quenches what is generally considered the most toxic and damaging free radical produced in the organism, the hydroxyl radical (.OH). Melatonin production in the pineal gland declines progressively with age such that in old animals and e...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:Anxiety and depression have dramatic impact on human and animal behaviors. We take an interdisciplinary approach and review the existing experimental models of anxiety and depression in order to promote further understanding of neurobiological aspects of anxiety and depression. ...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：:This study evaluates the role of glycine in in vivo modulation of the activity of excitatory amino acid receptors sensitive to N-methyl-D-aspartate (NMDA) in the rabbit hippocampus. Changes of extracellular calcium concentration were studied by the microdialysis technique combined with 45Ca-utilizing clearance method....
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:In 6 normotensive Wistar-Kyoto (WKY) and 6 spontaneously hypertensive rats (SHRs) anesthetized with urethane and chloralose, paralyzed, artificially ventilated, vagotomized with carotid sinus nerves bilaterally cut, somatosympathetic reflex discharges were recorded in cervical and renal nerves by stimulating group II ...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:The parabrachial complex has been related to various rewarding or aversive behavioral processes, including taste aversion learning and conditioned place aversion. This study examined the effect of tiapride, an antagonist of D2/D3 dopaminergic receptors, on place aversion induced by electrical stimulation of the extern...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：:Clinical and immunopathological evidence support a potential role of inflammatory cytokines in Alzheimer's disease (AD). However, studies examining the association between cytokine gene polymorphisms and risk of developing AD yielded conflicting results. The objective of our study was to evaluate the association betwe...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:The registration of the step phases and the relations between them for all of the four limbs were described in the amygdalar, rubral and funicular cats. The evident changes in motor behavior observed after damage of the amygdala and red nucleus did not result from coordination disorders. Conversely, the damage of the ...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:Sham operated controls and four groups of rats subjected to ablation of various parts of their frontal cortex were compared in food and water intake and four behavioural tasks. The ablations were aimed at removing (1) the ventral prefrontal cortex, (2) the dorsal part of the medial prefrontal cortex, (3) the total med...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Oxaliplatin is a third-generation, platinum-based antitumor drug used to treat colorectal cancer. Since its main adverse effect is neuropathic pain resulting from chemotherapy‑induced peripheral neuropathy (CIPN), this drug is used to study the neurobiology of CIPN in rodents and to search for analgesics that could at...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2018-01-01 00:00:00
