Abstract:
:Laser Raman spectroscopy has been used detect structural changes in troponin C induced by Ca2+ binding. Addition of Ca2+ - Mg2+ sites produces perturbations in the amide III region of the spectrum indicative of increased alpha-helical content, and in regions of the spectrum corresponding to carboxylate, thiol, and phenol side chains. However, Ca2+ binding to the low affinity Ca2+ - specific sites is not detected by laser Raman spectral changes.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Carew EB,Leavis PC,Stanley HE,Gergely Jdoi
10.1016/S0006-3495(80)85099-5subject
Has Abstractpub_date
1980-05-01 00:00:00pages
351-8issue
2eissn
0006-3495issn
1542-0086pii
S0006-3495(80)85099-5journal_volume
30pub_type
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