Information-theoretic significance of Gibbs energy supply to editing mechanisms.

Abstract:

:If a branched multistep editing mechanism is implemented by an enzyme with a single site for the specific substrates, there is no reason to believe that the number of testing steps is fixed and cannot be controlled by some external factors. The paper considers the mechanisms of single- or multistep editing done in response to various factors, particularly to the value of displacement from the reaction equilibrium. To avoid a complicated analysis of a fully specified case, which would be likely to obscure the general significant features, the operating modes of those mechanisms are estimated using the method of minimizing associated information gains. It turns out that sufficiently far from equilibrium the variable mechanisms can essentially operate just as well as the fixed multistep mechanisms.

journal_name

Biophys J

journal_title

Biophysical journal

authors

Kremen A

doi

10.1016/S0006-3495(82)84469-X

subject

Has Abstract

pub_date

1982-11-01 00:00:00

pages

149-54

issue

2

eissn

0006-3495

issn

1542-0086

pii

S0006-3495(82)84469-X

journal_volume

40

pub_type

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