Abstract:
:If a branched multistep editing mechanism is implemented by an enzyme with a single site for the specific substrates, there is no reason to believe that the number of testing steps is fixed and cannot be controlled by some external factors. The paper considers the mechanisms of single- or multistep editing done in response to various factors, particularly to the value of displacement from the reaction equilibrium. To avoid a complicated analysis of a fully specified case, which would be likely to obscure the general significant features, the operating modes of those mechanisms are estimated using the method of minimizing associated information gains. It turns out that sufficiently far from equilibrium the variable mechanisms can essentially operate just as well as the fixed multistep mechanisms.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Kremen Adoi
10.1016/S0006-3495(82)84469-Xsubject
Has Abstractpub_date
1982-11-01 00:00:00pages
149-54issue
2eissn
0006-3495issn
1542-0086pii
S0006-3495(82)84469-Xjournal_volume
40pub_type
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