Abstract:
:The slow-releasing artificial tear (SR-AT) is a soluble polymer in solid form. Placed in the inferior cul-de-sac and allowed to dissolve, it is used to treat dry-eye patients. The SR-AT was studied in two phases. The short-term cross-over study of 40 patients was completed in October 1976. The long-term open study is still in progress. Of 37 patients who started the long-term study, 18 are still using the inserts-a study retention of 49%.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Lamberts DW,Langston DP,Chu Wdoi
10.1016/s0161-6420(78)35610-4subject
Has Abstractpub_date
1978-08-01 00:00:00pages
794-800issue
8eissn
0161-6420issn
1549-4713pii
S0161-6420(78)35610-4journal_volume
85pub_type
临床试验,杂志文章,随机对照试验相关文献
OPHTHALMOLOGY文献大全abstract:PURPOSE:To evaluate the efficacy of a reading rehabilitation program (RRP) specifically designed for patients with impaired central vision from age-related macular degeneration (AMD) and the impact of the program on the quality of life (QoL) and to determine any predictable reading performance improvements between visi...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.07.035
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To investigate vitreous levels of reactive oxygen species (ROS) in patients with proliferative diabetic retinopathy (PDR) and analyze ROS levels among different groups of PDR patients. DESIGN:Retrospective case-control study. PARTICIPANTS:Thirty-nine eyes of 39 patients with PDR and 16 eyes of 16 non-PDR pa...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2007.05.041
更新日期:2008-04-01 00:00:00
abstract::The authors studied 11 eyes of 10 patients who complained of a recent decrease in vision and whose eyes had the clinical appearance of stage 5 retinopathy of prematurity (ROP) as diagnosed by the presence of a dense, opaque retrolenticular membrane. Patients ranged in age from 4 to 33 years, and birth weights ranged f...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32170-5
更新日期:1991-07-01 00:00:00
abstract::A retrospective multivariate analysis of 264 consecutive cases of vitrectomy for removal of epiretinal membranes of the macula was performed. Two main preoperative prognostic factors were identified that were associated with the visual outcome of surgery: (1) the preoperative visual acuity, and (2) the duration of blu...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33689-3
更新日期:1986-05-01 00:00:00
abstract:PURPOSE:The purpose of this study is to examine the changes of blood-aqueous barrier function in cases of central or branch retinal vein occlusion. METHODS:In addition to fluorophotometry of the aqueous humor and posterior vitreous, the authors used a method that quantifies protein in the aqueous (aqueous flare) by me...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(92)31875-5
更新日期:1992-06-01 00:00:00
abstract:OBJECTIVE:To investigate the long-term surgical outcome of Brown syndrome using an intraoperative adjustable superior oblique (SO) tendon suture spacer. DESIGN:Retrospective case series. PARTICIPANTS:Thirteen patients with congenital unilateral Brown syndrome operated on at the Wolfe Eye Clinic from 2001 through 2007...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.04.007
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:To report the histopathologic findings of eyes from a patient with Leigh's syndrome associated with the T 8993-G point mutation in mitochondrial DNA (mtDNA). DESIGN:Case report. INTERVENTION:A child with hypotonia, developmental delay, persistent lactic acidosis, seizures, and ataxia died of aspiration pneu...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00110-x
更新日期:2000-07-01 00:00:00
abstract::A 38-year-old male homosexual with the new Acquired Immunodeficiency Syndrome (AIDS) had biopsy proven Kaposi's sarcoma of the right palpebral conjunctiva, extraocular mucocutaneous areas, and lymph nodes. Histologically, the palpebral tumor was characterized by atypical spindle cell proliferation and multiple slit-li...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(83)80011-6
更新日期:1983-08-01 00:00:00
abstract:PURPOSE:The authors analyzed all the complications associates with the first 100 hydroxyapatite orbital implants performed by one surgeon, and compare scleral wrapping versus Dexon mesh (polyglycolic acid, Davis & Geck, Manati, Puerto Rico) wrapping in light of these complications. BACKGROUND:Prior studies have not in...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/s0161-6420(97)30316-9
更新日期:1997-02-01 00:00:00
abstract::The interactions between rabbit corneal epithelium and endothelium were investigated in an organ culture model using scanning electron microscopy and correlative light microscopy. Following mechanical removal of corneal endothelium, corneal epithelium was observed to migrate across the cut surface of the corneal strom...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(84)34250-6
更新日期:1984-06-01 00:00:00
abstract:PURPOSE:Patients undergoing enucleation for uveal melanoma need to be informed of the possibility of phantom eye syndrome (PES). The number with uveal melanoma in PES studies has been small. Aims were to: (1) determine the prevalence, symptoms, and characteristics of PES and to test associations of PES symptoms with so...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2015.04.005
更新日期:2015-08-01 00:00:00
abstract::The authors report seven patients in whom the acute retinal necrosis (ARN) syndrome developed shortly after cutaneous varicella zoster infection. The length of time between the skin infection and ARN varied from 5 days to 3 months. Both eyes were affected in one of seven cases. The ophthalmic branch of cranial nerve V...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(87)33405-0
更新日期:1987-06-01 00:00:00
abstract:PURPOSE:To identify effective methods to increase the number of cataract surgeries in a rural setting in Pucheng County of Shaanxi Province, northwestern China. DESIGN:Community-based randomized interventional study. PARTICIPANTS:Four hundred thirty-two patients 50 years of age or older with operable cataract who had...
journal_title:Ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ophtha.2012.07.087
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:To report the success rate of endoscopically assisted balloon dacryoplasty (EADCP) for treatment of acquired incomplete nasolacrimal duct obstructions (NLDOs). DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Records of patients treated for incomplete NLDOs with EADCP by one of the authors (WLW)...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2003.06.013
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To assess the posterior corneal power and asphericity changes after myopic laser in situ keratomileusis (LASIK) and to correlate these changes with the amount of correction and the residual stromal bed thickness. DESIGN:Prospective nonrandomized (self-controlled) comparative study. PARTICIPANTS:Fifty-seven ...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/s0161-6420(00)00581-9
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:As of December 31, 2000, the neodymium:yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy rate for the Alcon AcrySof intraocular lens (IOL) as measured in our database was 3.3%. This was the lowest of any IOL model used in the United States. Only 12 of 361 cases required treatment. We analyzed possibl...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(02)01116-8
更新日期:2002-08-01 00:00:00
abstract::The technique and results of conjunctival autograft transplantation for advanced and recurrent pterygium are presented for 57 eyes of 54 patients. The pterygia were primary in 16 eyes and recurrent in 41; among the latter group, 14 patients had diplopia resulting from cicatricial involvement of the medial rectus muscl...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)33831-9
更新日期:1985-11-01 00:00:00
abstract:PURPOSE:To compare 2.0 mg ranibizumab (RBZ) injections with 0.5 mg RBZ for eyes with center-involved diabetic macular edema (DME). DESIGN:Randomized, controlled, double-masked (to the dose), interventional, multicenter clinical trial. PARTICIPANTS:A total of 152 patients (152 eyes) with DME. METHODS:Eligible eyes we...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ophtha.2016.08.040
更新日期:2016-12-01 00:00:00
abstract::The authors studied 50 eyes with atrophic (dry) macular degeneration (geographic atrophy of age-related macular degeneration [GAMD], in 50 consecutive patients for 2 to 6 years (average, 3.4 years). There were 35 women and 15 men ranging in age from 60 to 89 years (average, 73 years). The areas of atrophy tended to fo...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32694-7
更新日期:1989-10-01 00:00:00
abstract:PURPOSE:To study the efficacy of liposomal benzoporphyrin derivative (BPD) (Verteportin) for the angiographic visualization and photodynamic therapy (PDT) of experimental iris neovascularization. METHODS:Experimental iris neovascularization was induced in eight cynomolgus monkey eyes by occluding all the branch retina...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(97)30151-1
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVE:To report long-term follow-up of Intacs microthin prescription inserts for the management of post-LASIK corneal ectasia. DESIGN:Long-term (5 years), retrospective, nonrandomized study. PARTICIPANTS:Eight eyes of 5 patients with post-LASIK corneal ectasia (3 men and 2 women) ages 31 to 54 years (mean age+/-s...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.05.043
更新日期:2006-11-01 00:00:00
abstract:PURPOSE:A MATLAB-based (The MathWorks, Inc, Natick, MA) computer program (the ganglion cell-inner plexiform layer [GCIPL] hemifield test) for automated detection of GCIPL thickness difference across the horizontal raphe was developed, and its glaucoma diagnostic performance was assessed. DESIGN:Cross-sectional study. ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2015.07.013
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:To characterize the types and frequencies of image artifacts associated with macular scanning using 2 common spectral-domain optical coherence tomography (SD OCT) instruments and to evaluate the impact of artifacts on foveal thickness measurements. DESIGN:Retrospective, observational chart review. PARTICIPANT...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.10.029
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:To compare the prevalence of and risk factors for primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) in urban and rural populations in the Andhra Pradesh Eye Disease Study. DESIGN:A population-based, cross-sectional study using a stratified, random, cluster, and systematic sampling st...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.11.006
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To review the evidence regarding the safety and efficacy of current anti-vascular endothelial growth factor (VEGF) pharmacotherapies for the treatment of diabetic macular edema (DME). METHODS:Literature searches last were conducted in September 2011, in PubMed with no date restrictions, limited to articles p...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ophtha.2012.07.058
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:To determine the outcome of pediatric dacryocystorhinostomy (DCR) for large mucoceles or for primary nasolacrimal duct obstruction unresponsive to multiple probings. DESIGN:Retrospective noncomparative case series. PARTICIPANTS:One hundred thirty-four external dacryocystorhinostomies were performed in 121 c...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(01)00699-6
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVE:To compare the reliability and the agreement in measuring central corneal thickness (CCT) using the following technologies: RTVue Fourier-domain optical coherence tomography (Optovue, Inc., Fremont, CA), Pentacam (Oculus, Inc., Wetzlar, Germany), and ultrasonic pachymetry (USP; Pocket-II; Quantel Medical, Inc...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.03.002
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to describe the clinical features and biometric findings in the eyes of children with coloboma and to develop a classification of coloboma that correlates with visual function. DESIGN:Retrospective observational case series. PARTICIPANTS:One hundred thirteen children and young ad...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(99)00140-2
更新日期:2000-03-01 00:00:00
abstract::Malignant rhabdoid tumor (MRT), originally described as a sarcomatous variant of Wilms' tumor, is now recognized as a distinct, highly malignant entity. The authors describe, for the first time, a primary tumor of the orbit with histologic, immunohistochemical, and ultrastructural features of MRT. Their findings sugge...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32666-2
更新日期:1989-11-01 00:00:00
abstract:PURPOSE:To describe the prevalence and signs of early and late age-related macular degeneration (AMD) in an old cohort. DESIGN:Population-based cohort study. PARTICIPANTS:We included 5272 persons aged ≥66 years, randomly sampled from the Reykjavik area. METHODS:Fundus images were taken through dilated pupils using a...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.08.044
更新日期:2011-05-01 00:00:00