Does mitral valve prolapse cause nonspecific symptoms?

Abstract:

:I studied the prevalence and symptoms of idiopathic mitral valve prolapse by auscultation in 972 consecutive patients in an adult general medical population. Forty-five patients (4.6%) had idiopathic mitral valve prolapse defined by a nonejection click with or without a late systolic murmur. The prevalence was not significantly different in men and women. The mean age (49.9 yr) and age distribution of patients with prolapse were similar to those of patients without prolapse (47.7 yr). The prevalence of dizziness (4.1% vs. 1.5%), fatigue (4.4% vs. 2.6%), and palpitations (4.4% vs. 1.3%), was not significantly greater in patients with or without prolapse. Atypical chest pain (13% vs. 4.3%) and chronic anxiety (8.8% vs. 2.9%) were more frequent (less than 0.05) in the patients with prolapse than in those without prolapse. Of the patients with prolapse, 29 were healthy without clinically identifiable diseases while 16 had medical diseases. In the group without prolapse, 184 patients were healthy and 707 had other diseases. When patients with isolated prolapse without other associated diseases were compared to healthy patients without prolapse, the prevalence of atypical chest pain (17.4% vs. 17.2%) and chronic anxiety (7.1% vs. 10.3%) were not significantly different. When patients with prolapse and other diseases were compared to patients without prolapse and other diseases, the prevalence of atypical chest pain (6.2% vs. 1.1%) and chronic anxiety (6.2% vs. 1.7%) was again not significantly different. Thirty-two patients without prolapse were suspected but not confirmed of having disease and were not included in this analysis. The results would have been unaltered by their inclusion in the diseased group without prolapse.

journal_name

Int J Cardiol

authors

Uretsky BF

doi

10.1016/0167-5273(82)90069-9

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

435-42

issue

5-6

eissn

0167-5273

issn

1874-1754

pii

0167-5273(82)90069-9

journal_volume

1

pub_type

杂志文章
  • Residual risk of cardiovascular mortality in patients with coronary heart disease: the EUROASPIRE risk categories.

    abstract:BACKGROUND:The EUROASPIRE I, II and III surveys revealed high prevalences of modifiable risk factors in the high priority group of coronary patients all over Europe. The potential to further reduce coronary heart disease (CHD) morbidity and mortality rates is still considerable. We report here on the relative risk of c...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2012.10.051

    authors: De Bacquer D,Dallongeville J,Kotseva K,Cooney MT,Pajak A,Deckers JW,Mayer O,Vanuzzo D,Lehto S,Fras Z,Östor E,Ambrosio GB,De Backer G,Wood D,Keil U,Sans S,Graham I,Pyörälä K

    更新日期:2013-09-30 00:00:00

  • Drug eluting balloon versus drug eluting stent in percutaneous coronary interventions: insights from a meta-analysis of 1462 patients.

    abstract:BACKGROUND:Drug eluting balloons (DEB) have been developed to overcome the limitations of drug eluting stents (DES), but clinic results of various DEB studies are still not consistent. Thus, we performed a meta-analysis to compare outcomes of DEB and DES for the treatment of coronary artery disease (CAD). METHODS:Medl...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.ijcard.2013.07.161

    authors: Lupi A,Rognoni A,Secco GG,Porto I,Nardi F,Lazzero M,Rossi L,Parisi R,Fattori R,Genoni G,Rosso R,Stella PR,Sheiban I,Bolognese L,Liistro F,Bongo AS,Agostoni P

    更新日期:2013-10-12 00:00:00

  • p38α MAPK inhibits stretch-induced JNK activation in cardiac myocytes through MKP-1.

    abstract::Mechanical stretch is a major determinant that leads to heart failure, which is associated with a steady increase in myocardial angiotensinogen (Aogen) expression and formation of the biological peptide angiotensin II (Ang II). c-jun NH2-terminal kinase (JNK) and p38α have been found to have opposing roles on stretch-...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2015.10.109

    authors: Feng H,Gerilechaogetu F,Golden HB,Nizamutdinov D,Foster DM,Glaser SS,Dostal DE

    更新日期:2016-01-15 00:00:00

  • Lipid profiles and endothelial function with low-dose hormone replacement therapy in postmenopausal women at risk for coronary artery disease: a randomized trial.

    abstract:AIMS:To compare the effect of low (0.3 mg) and commonly prescribed (0.625 mg) doses of conjugated equine estrogens (CEE) on brachial artery flow-mediated dilation and lipid profiles. METHODS AND RESULTS:Twenty-five postmenopausal women (mean age, 65+/-6 years) at risk for coronary artery disease (CAD) (> or =2 establi...

    journal_title:International journal of cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0167-5273(02)00505-3

    authors: Mercuro G,Vitale C,Fini M,Zoncu S,Leonardo F,Rosano GM

    更新日期:2003-06-01 00:00:00

  • A cornerstone of heart failure treatment is not effective in experimental right ventricular failure.

    abstract:BACKGROUND:Right ventricular (RV) failure due to increased pressure load causes significant morbidity and mortality in patients with congenital heart diseases and pulmonary arterial hypertension. It is unknown whether renin-angiotensin-aldosterone-system (RAAS) inhibition (the cornerstone of left ventricular failure tr...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2013.08.102

    authors: Borgdorff MA,Bartelds B,Dickinson MG,Steendijk P,Berger RM

    更新日期:2013-11-05 00:00:00

  • Clinical significance of papillary muscle late enhancement detected via cardiac magnetic resonance imaging in patients with single old myocardial infarction.

    abstract:BACKGROUND:Contrast-enhanced cardiac magnetic resonance imaging (MRI) can depict papillary muscle (PM) necrosis or fibrosis by late enhancement (LE) of PM, but its clinical significance in old myocardial infarction (OMI) has been little understood. METHODS:Myocardial LE and PM-LE were detected with contrast imaging in...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2010.04.037

    authors: Okayama S,Uemura S,Soeda T,Onoue K,Somekawa S,Ishigami K,Watanabe M,Nakajima T,Fujimoto S,Saito Y

    更新日期:2011-01-07 00:00:00

  • Recurrent pulmonary embolism with non-mobile thrombus in a patient with leiomyosarcoma of the left renal vein.

    abstract::We describe the case of a man who suffered recurrent pulmonary embolisms despite well-conducted oral anticoagulant therapy. Echocardiography and helical computed tomography revealed a non-mobile right atrial mass related to a leiomyosarcoma of the left renal vein. The prognosis of such a disease is bad and the patient...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2005.07.044

    authors: Mansencal N,El Hajjam M,Vieillard-Baron A,Pelage JP,Lacombe P,Dubourg O

    更新日期:2006-09-20 00:00:00

  • Contemporary review on the pathogenesis of takotsubo syndrome: The heart shedding tears: Norepinephrine churn and foam at the cardiac sympathetic nerve terminals.

    abstract::Takotsubo syndrome (TS), an increasingly recognized acute cardiac disease entity, is characterized by a unique pattern of circumferential and typically regional left ventricular wall motion abnormality resulting in a conspicuous transient ballooning of the left ventricle during systole. The mechanism of the disease re...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2016.11.086

    authors: Y-Hassan S,De Palma R

    更新日期:2017-02-01 00:00:00

  • Influence of updated guidelines on short- and long-term mortality in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS).

    abstract:AIM:In 2002 the ACC/AHA guidelines for the management of patients with unstable angina (UA) and non-ST-segment elevation myocardial infarction (NSTEMI) were updated. We aimed to answer whether the implementation of updated guidelines was capable of influencing short- and long-term mortality in these patients. METHODS:...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2011.02.073

    authors: Vogel B,Hahne S,Kozanli I,Kalla K,Jarai R,Freynhofer M,Smetana P,Nürnberg M,Geppert A,Unger G,Huber K

    更新日期:2012-09-06 00:00:00

  • Altered coronary endothelial function in a patient with asymptomatic left ventricular dysfunction.

    abstract::Coronary endothelial dysfunction has been demonstrated in patients with symptomatic heart failure. Furthermore the endothelium has been implicated in the pathogensis of cardiomyopathy in patients with normal coronary angiograms and no other known causes of heart failure. Herein we describe an asymptomatic patient with...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(95)02513-8

    authors: Cannan CR,McGoon MD,Holmes DR Jr,Lerman A

    更新日期:1996-02-01 00:00:00

  • Value of analysis of the evolution of the pattern of the ST segment in exercise electrocardiograms.

    abstract::We analysed retrospectively the exercise electrocardiogram records of all patients with positive exercise tests which, on subsequent coronary angiography, proved to be "false positives". The exercise records of 10 "false positive" patients were compared with the records of 10 patients with true positive tests in the s...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(90)90121-k

    authors: Bajaj R,Wasir HS

    更新日期:1990-12-01 00:00:00

  • Skeletal muscle fibres synthesis in heart failure: role of PGC-1alpha, calcineurin and GH.

    abstract:BACKGROUND:Patients with congestive heart failure (CHF) have decreased exercise capacity because of muscle fatigability. Symptoms are due to a specific myopathy with increased expression of fast type II fibres, fast MHCs and muscle atrophy. PGC-1alpha, a potent transcriptional coactivator for nuclear receptors, induces...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2004.10.059

    authors: Vescovo G,Ravara B,Gobbo V,Angelini A,Dalla Libera L

    更新日期:2005-10-10 00:00:00

  • Hypertonic saline with furosemide for the treatment of acute congestive heart failure: a systematic review and meta-analysis.

    abstract:BACKGROUND:Advanced congestive heart failure (CHF) therapies include intravenous inotropic agents, change in class of diuretics, and venous ultrafiltration or hemodialysis. These modalities have not been associated with improved prognosis and are limited by availability and cost. Compared to high-dose furosemide alone,...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ijcard.2014.03.020

    authors: Gandhi S,Mosleh W,Myers RB

    更新日期:2014-05-01 00:00:00

  • Anatomical consideration of the radial artery for transradial coronary procedures: arterial diameter, branching anomaly and vessel tortuosity.

    abstract:BACKGROUND:The radial artery is currently regarded as a useful vascular access site for coronary procedures. Adequate anatomical information of the radial artery should be helpful in performing the transradial coronary procedure. Therefore, we tried to evaluate the size of radial artery, the incidence and clinical sign...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2004.03.061

    authors: Yoo BS,Yoon J,Ko JY,Kim JY,Lee SH,Hwang SO,Choe KH

    更新日期:2005-06-08 00:00:00

  • Incidence, timing, predictors and impact of acute heart failure complicating ST-segment elevation myocardial infarction in patients treated by primary percutaneous coronary intervention.

    abstract:BACKGROUND:Acute heart failure (AHF) complicating ST-segment elevation myocardial infarction (STEMI) is recognized as an ominous complication. Previous studies mostly reported outcomes of heterogeneous, non-contemporary population. Moreover, few studies assessed the prognosis of AHF according to its timing. This study ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2016.07.040

    authors: Auffret V,Leurent G,Gilard M,Hacot JP,Filippi E,Delaunay R,Rialan A,Rouault G,Druelles P,Castellant P,Coudert I,Boulanger B,Treuil J,Bot E,Bedossa M,Boulmier D,Le Guellec M,Donal E,Le Breton H

    更新日期:2016-10-15 00:00:00

  • New predictors of mortality in adults with congenital heart disease and pulmonary hypertension: Midterm outcome of a prospective study.

    abstract:BACKGROUND:Patients with CHD-PAH have a limited prognosis. In daily practice, combination therapy is often initiated after a clinical event. Although clinical events have been associated with a poor prognosis in idiopathic PAH, data on this association are limited in CHD-PAH. The aim of this study was to determine whet...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2014.11.222

    authors: Schuuring MJ,van Riel AC,Vis JC,Duffels MG,van Dijk AP,de Bruin-Bon RH,Zwinderman AH,Mulder BJ,Bouma BJ

    更新日期:2015-02-15 00:00:00

  • Association between polymorphisms of the HSPB7 gene and Cheyne-Stokes respiration with central sleep apnea in patients with dilated cardiomyopathy and congestive heart failure.

    abstract:BACKGROUND:CSR-CSA is frequent in patients with CHF. Dilated cardiomyopathy (DCM) is a structural heart disease with strong genetic background, yet one of the leading etiological causes of CHF. Studies have showed that the HSPB7 gene is associated with DCM. OBJECTIVES:We aimed to explore the prevalence of polymorphism...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2016.07.107

    authors: Wang M,Ding H,Kang J,Hu K,Lu W,Zhou X,Xu L

    更新日期:2016-10-15 00:00:00

  • The effects of ventricular asynchrony on myocardial perfusion.

    abstract::Asynchronous depolarization and contraction sequence, secondary to intraventricular conduction defects or to permanent right ventricular apical pacing, is associated with adverse effects that may be clinically evident in the failing heart. Experimental and clinical studies have suggested that asynchronous ventricular ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2006.03.091

    authors: Kyriakides ZS,Manolis AG,Kolettis TM

    更新日期:2007-06-25 00:00:00

  • Feelings of being disabled as a prognostic factor for mortality in men and women post-PCI up to 12years.

    abstract:BACKGROUND:It remains unclear whether feelings of being disabled are a relevant psychological factor that determines long term outcome after percutaneous coronary intervention (PCI). Therefore, we evaluated 'feelings of being disabled' as an independent risk factor for mortality 12years post-PCI. METHODS:The study pop...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2017.09.026

    authors: Bergmann MJ,Utens EMWJ,de Jager TAJ,Radhoe SP,Daemen J,Lenzen MJ,van Domburg RT,Dulfer K

    更新日期:2017-12-15 00:00:00

  • Heart failure and cognitive dysfunction.

    abstract::It has been estimated that 5.1million Americans suffer from heart failure. Cognitive impairment has been described as a consequence of heart failure in numerous studies spanning the last three decades. This systematic review helps differentiate "cognitive impairment" into mild cognitive impairment, dementia, and delir...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2014.10.087

    authors: Ampadu J,Morley JE

    更新日期:2015-01-15 00:00:00

  • Arterial pressure and aging.

    abstract::Systolic arterial pressure increases with aging. This increase encompasses both the clinically normal and hypertensive ranges of pressure and is due in part to arterial stiffening. To what extent it may be modulated by life style changes that accompany aging is unknown. The stiffer arterial tree transmits the pulse wa...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/0167-5273(89)90097-1

    authors: Lakatta EG

    更新日期:1989-01-01 00:00:00

  • Persistent superior exercise performance and quality of life long-term after arterial switch operation compared to that after atrial redirection.

    abstract:BACKGROUND:In the end of the last century arterial switch operation (ASO) replaced atrial redirection according to Senning or Mustard as the surgical technique for infants with transposition of the great arteries (TGA). Better survival with the new technique has been shown. However, exercise performance and quality of ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2011.10.116

    authors: Müller J,Hess J,Hörer J,Hager A

    更新日期:2013-06-20 00:00:00

  • Localization of CD8 T cell epitope within cardiac myosin heavy chain-α334-352 that induces autoimmune myocarditis in A/J mice.

    abstract:BACKGROUND:Cardiac myosin heavy chain-α (Myhc), an intracellular protein expressed in the cardiomyocytes, has been identified as a major autoantigen in cardiac autoimmunity. In our studies with Myhc334-352-induced experimental autoimmune myocarditis in A/J mice (H-2a), we discovered that Myhc334-352, supposedly a CD4 T...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2015.09.016

    authors: Massilamany C,Gangaplara A,Basavalingappa RH,Rajasekaran RA,Khalilzad-Sharghi V,Han Z,Othman S,Steffen D,Reddy J

    更新日期:2016-01-01 00:00:00

  • Cardiac MR1 and peripartum cardiomyopathy.

    abstract::Cardiac MRI brings great benefits in the comprehension of the mechanism(s) involved in the genesis of peripartum cardiomyopathy (PPC). Cardiac MRI may also procure prognostic information. Because this is a rare affection, it seems necessary to systematically study PPC with this safe, non invasive and reliable tool. Cr...

    journal_title:International journal of cardiology

    pub_type: 评论,信件

    doi:10.1016/j.ijcard.2008.11.142

    authors: Leurent G

    更新日期:2010-07-23 00:00:00

  • Norepinephrine-induced left ventricular dysfunction in anesthetized and conscious, sedated dogs.

    abstract::These studies were conducted to evaluate effects of high dose norepinephrine infusion on left ventricular function in anesthetized and conscious dogs. Separate groups of pentobarbital anesthetized closed-chest dogs received norepinephrine infusion for 90 min followed by 1 h of recovery. Arterial pressure, electrocardi...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(94)90051-5

    authors: Movahed A,Reeves WC,Mehta PM,Gilliland MG,Mozingo SL,Jolly SR

    更新日期:1994-06-01 00:00:00

  • Effects of isometric exercise on the diastolic function in patients with severe aortic stenosis with or without coronary lesion.

    abstract:BACKGROUND:There is no literature evaluating the effect of exercise on patients with aortic stenosis, in which patients with and without coronary artery disease were assessed separately. OBJECTIVE:To assess the effects of isometric exercise on the diastolic function in patients with aortic stenosis (AS). METHODS:18 p...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2004.10.014

    authors: Gabay J,Donato M,Pascua A,Gelpi RJ,Grinfeld L

    更新日期:2005-09-15 00:00:00

  • Doppler imaging of an inadvertent anastomosis of modified Blalock-Taussig shunt to the right upper pulmonary vein.

    abstract::In a newborn infant with a complex congenital heart disease, a right modified Blalock-Taussig anastomosis was created because of the pulmonary atresia. A 4-mm Gore-Tex tube was inadvertently connected to the upper right pulmonary vein. Clinical signs of an arteriovenous fistula with no improvement in oxygen saturation...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(94)90137-6

    authors: Robida A

    更新日期:1994-11-01 00:00:00

  • A rare congenital coronary artery anomaly: anomalous of the left anterior descending coronary artery arising from the right coronary artery and review of the literature.

    abstract::Most coronary anomalies are clinically asymptomatic. However some of them may present with chest pain, syncope, heart failure and sudden death. Anomalous left anterior descending artery arising from right coronary artery is a very rare coronary anomaly. ...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2008.11.078

    authors: Karabay KO,Bağirtan B,Erdim R,Uysal E,Vural M

    更新日期:2010-04-30 00:00:00

  • Borrelia-like organism in heart capillaries of patient with Lyme-disease seen by electron microscopy.

    abstract::A case of a patient who developed an acute myocarditis due to Lyme disease is reported. An increased serum antibody titer to Borrelia burgdorferi suggested a diagnosis and in addition of basic clinical methods, endomyocardial biopsy performed and analyzed by transmission electron microscopy. The lumen of myocardial ca...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2008.12.165

    authors: Lalosevic D,Lalosevic V,Stojsic-Milosavljevic A,Stojsic D

    更新日期:2010-12-03 00:00:00

  • Effort dyspnea after coronary artery bypass grafting.

    abstract::Two series of consecutive patients with disabling effort angina were studied prospectively. From the first series, 94 survivors were followed up 9 months after coronary artery bypass grafting. Thirty-five patients (37%) reported that they still suffered from effort angina. Another 26 patients (28%) also used to stop w...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(86)90033-1

    authors: Ekeström S,Forssell G,Jonasson R,Orinius E

    更新日期:1986-06-01 00:00:00