Abstract：
BACKGROUND:The elevation of blood pressure levels has been recognised as a determinant of the risk for several common cardiovascular diseases. In this work we examined the effect of Mediterranean type of diet on coronary risk in subjects with hypertension. METHODS:CARDIO2000 consisted of 848 randomly selected hospitalised patients (695 males, 58 +/- 10 years old; 153 females, 65 +/- 9 years old) for first event of coronary heart disease (CHD) and 1078 paired, by sex-age, hospitalised controls without CHD. The adoption of the Mediterranean diet was assessed through a validated questionnaire developed by the National School of Public Health. RESULTS:418 (49%) of the patients and 303 (28%) of the controls were hypertensive. Of them 21 (5%) patients and 36 (12%) controls were unaware of their condition, 94 (22%) and 34 (11%) were untreated, 148 (35%) and 111 (36%) were uncontrolled and 155 (38%) and 122 (41%) were controlled (P<0.01). One hundred and sixty-two (19%) of the patients and 265 (25%) of the controls (P<0.01) adopted the Mediterranean type of diet. Our results suggest that the adoption of Mediterranean diet reduces the risk of developing acute coronary syndromes by 17% (odds ratio=0.83, 95% CI 0.73--0.88, P<0.01) in controlled hypertensive subjects, by 8% (odds ratio=0.92, 95% CI 0.87-0.95, P<0.05) in unaware, by 7% (odds ratio=0.93, 95% CI 0.88-0.95, P<0.05) in acknowledged but uncontrolled and by 20% (odds ratio=0.80, 95% CI 0.71-0.89, P<0.01) in normotensive subjects. CONCLUSION:According to our findings the adoption of the Mediterranean diet is associated with the reduction of coronary risk in hypertensive subjects.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Panagiotakos DB,Chrysohoou C,Pitsavos C,Tzioumis K,Papaioannou I,Stefanadis C,Toutouzas Pdoi
10.1016/s0167-5273(01)00611-8subject
Has Abstractpub_date
2002-02-01 00:00:00pages
141-7issue
2eissn
0167-5273issn
1874-1754pii
S0167527301006118journal_volume
82pub_type
杂志文章,多中心研究abstract：:The formation of an intravascular thrombus underlies the clinical symptoms associated with acute coronary syndromes (ACS). Plaque rupture signals the recruitment and activation of platelets, initiation of the coagulation cascade, and generation of thrombin, resulting in the formation of a platelet-rich thrombus. Use o...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
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abstract：:The prognostic significance of right ventricular ejection fraction, measured by radionuclide ventriculography, was assessed in 168 consecutive patients with inferior myocardial infarction. Right ventricular ejection fraction was 0.40 or less in 35 patients. Over a follow-up period of 40 months, there were 15 deaths in...
journal_title：International journal of cardiology
pub_type： 杂志文章
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journal_title：International journal of cardiology
pub_type： 社论
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pub_type： 历史文章,杂志文章
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abstract：:Current studies evaluating the effect of serum potassium levels on mortality in patients with ST elevation myocardial infarction (STEMI) are lacking. We analyzed retrospectively 3760 patients diagnosed with STEMI. Mean serum potassium levels were categorized accordingly: <3.0, 3.0 to <3.5, 3.5 to <4.0, 4.0 to <4.5, 4....
journal_title：International journal of cardiology
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journal_title：International journal of cardiology
pub_type： 杂志文章,评审
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pub_type： 杂志文章,meta分析,评审
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pub_type： 杂志文章
doi：10.1016/0167-5273(90)90088-m
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 信件
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pub_type： 临床试验,杂志文章,随机对照试验
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pub_type： 杂志文章,多中心研究
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journal_title：International journal of cardiology
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pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：International journal of cardiology
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更新日期：2017-01-15 00:00:00
