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Borrelia-like organism in heart capillaries of patient with Lyme-disease seen by electron microscopy.

Abstract：

:A case of a patient who developed an acute myocarditis due to Lyme disease is reported. An increased serum antibody titer to Borrelia burgdorferi suggested a diagnosis and in addition of basic clinical methods, endomyocardial biopsy performed and analyzed by transmission electron microscopy. The lumen of myocardial capillaries was founded mostly filled with detritus and fibrin precipitate, between them several bacterial fragments were identified. The electron-microscopic characteristics of the microorganisms in this specimen, revealing irregularly coiled appearance and consistent thickness of 0.2 μm, correspond to the spiral-like structure of Lyme disease borrelia. The presence of fibrin deposits on the capillary endothelium and necrosis of myocardiocytes, suggests that the cardiopathy in our patient was represent borrelia-mediated damage of the heart microcirculation.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Lalosevic D,Lalosevic V,Stojsic-Milosavljevic A,Stojsic D

doi

10.1016/j.ijcard.2008.12.165

subject

Has Abstract

pub_date

2010-12-03 00:00:00

pages

e96-8

issue

3

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(08)01599-4

journal_volume

145

pub_type

信件

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