Bioactive calcium pyrophosphate glasses and glass-ceramics.

abstract：:Multicomponent formulations coupled with complex processing conditions govern the final properties of photopolymerizable dental composites. In this study, a single test substrate was fabricated to support multiple formulations with a gradient in degree of conversion (DC), allowing the evaluation of multiple processing...

journal_title：Acta biomaterialia

authors： Lin-Gibson S,Sung L,Forster AM,Hu H,Cheng Y,Lin NJ

更新日期：2009-07-01 00:00:00

abstract：:Magnesium (Mg) medical devices are currently being marketed for orthopedic applications and have a complex degradation process which includes the evolution of hydrogen gas (H2). The effect of H2 exposure on relevant cell types has not been studied; and the concentration surrounding degrading Mg devices has not been qu...

journal_title：Acta biomaterialia

authors： Zhao D,Brown A,Wang T,Yoshizawa S,Sfeir C,Heineman WR

更新日期：2018-06-01 00:00:00

abstract：:The aim of this work was to study the phase transformation during the setting reaction of two calcium phosphate bone cements based on either alpha tricalcium phosphate (alpha-TCP) or tetracalcium phosphate (TetCP) initial solid phase, and a magnesium carbonate-phosphoric acid solution as the hardening liquid. Low mole...

journal_title：Acta biomaterialia

authors： Rau JV,Generosi A,Smirnov VV,Ferro D,Rossi Albertini V,Barinov SM

更新日期：2008-07-01 00:00:00

abstract：:Recently, endovascular coil embolization has been introduced to treat intracranial aneurysms because it has lower morbidity and mortality than surgical clipping. The endovascular coils prevent the extravasation of blood by decreasing the permeability of an aneurysm flow governed by Darcy's law. Here, we developed and ...

journal_title：Acta biomaterialia

authors： Kim MW,An S,Seok H,Jung H,Park DH,Yarin AL,Yoon SS

更新日期：2020-01-01 00:00:00

abstract：:Cardiac fibrosis, an important pathological feature of structural remodeling, contributes to ventricular stiffness, diastolic dysfunction, arrhythmia and may even lead to sudden death. Matrix stiffness, one of the many mechanical factors acting on cells, is increasingly appreciated as an important mediator of myocardi...

journal_title：Acta biomaterialia

authors： Xie J,Zhang Q,Zhu T,Zhang Y,Liu B,Xu J,Zhao H

更新日期：2014-06-01 00:00:00

abstract：:This study investigated whether a novel alkali-based surface modification enhances in vitro mineralization as well as in vivo bone formation around titanium (Ti) implants in a femoral condyle model of 36 male Wister rats. All implant surfaces were grit-blasted and then received either acid-etching treatment, alkali-ba...

journal_title：Acta biomaterialia

authors： Camargo WA,Takemoto S,Hoekstra JW,Leeuwenburgh SCG,Jansen JA,van den Beucken JJJP,Alghamdi HS

更新日期：2017-07-15 00:00:00

abstract：:The Laser Engineered Net Shaping (LENS) method was used to fabricate porous Ti implants. Porous Ti structures with controlled porosity in the range of 17-58 vol.% and pore size up to 800 microm were produced by controlling LENS parameters, which showed a broad range of mechanical strength of 24-463 MPa and a low Young...

journal_title：Acta biomaterialia

authors： Xue W,Krishna BV,Bandyopadhyay A,Bose S

更新日期：2007-11-01 00:00:00

abstract：:Bacterial interference using non-pathogenic Escherichia coli 83972 is a novel strategy for preventing catheter-associated urinary tract infection (CAUTI). Crucial to the success of this strategy is to establish a high coverage and stable biofilm of the non-pathogenic bacteria on the catheter surface. However, this non...

journal_title：Acta biomaterialia

authors： Zhu Z,Yu F,Chen H,Wang J,Lopez AI,Chen Q,Li S,Long Y,Darouiche RO,Hull RA,Zhang L,Cai C

更新日期：2017-12-01 00:00:00

abstract：:Synthetic polymer microarray technology holds remarkable promise to rapidly identify suitable biomaterials for stem cell and tissue engineering applications. However, most of previous microarrayed synthetic polymers do not possess biological ligands (e.g., peptides) to directly engage cell surface receptors. Here, we ...

journal_title：Acta biomaterialia

authors： Jia J,Coyle RC,Richards DJ,Berry CL,Barrs RW,Biggs J,James Chou C,Trusk TC,Mei Y

更新日期：2016-11-01 00:00:00

abstract：:In order to evaluate the effect of the nanostructure of calcium phosphate ceramics on osteoinductive potential, porous biphasic calcium phosphate (BCP) ceramics with a nano- or submicron structure were prepared via microwave sintering and compared to conventional BCP ceramics. The selective protein adsorption of bovin...

journal_title：Acta biomaterialia

authors： Li B,Liao X,Zheng L,Zhu X,Wang Z,Fan H,Zhang X

更新日期：2012-10-01 00:00:00

abstract：:Mast cells (MCs)_are recognized for their functional role in wound-healing and allergic and inflammatory responses - host responses that are frequently detrimental to implanted biomaterials if extended beyond acute reactivity. These tissue reactions impact especially on the performance of sensing implants such as cont...

journal_title：Acta biomaterialia

authors： Avula MN,Rao AN,McGill LD,Grainger DW,Solzbacher F

更新日期：2014-05-01 00:00:00

abstract：UNLABELLED:By means of appropriate cell type and scaffold, tissue-engineering approaches aim to construct grafts for cartilage repair. Pluripotent stem cells especially induced pluripotent stem cells (iPSCs) are of promising cell candidates due to the pluripotent plasticity and abundant cell source. We explored three d...

journal_title：Acta biomaterialia

authors： He P,Fu J,Wang DA

更新日期：2016-04-15 00:00:00

abstract：:This paper presents a strain-mediated phenomenological corrosion model, based on the discrete finite element modelling method which was developed for use with the ANSYS Implicit finite element code. The corrosion model was calibrated from experimental data and used to simulate the corrosion performance of a WE43 magne...

journal_title：Acta biomaterialia

authors： Galvin E,O'Brien D,Cummins C,Mac Donald BJ,Lally C

更新日期：2017-06-01 00:00:00

abstract：:Spherical bioactive glass 13-93 particles, with a particle size distribution of 50-125 microm, were combined with bioabsorbable poly-L,DL-lactide 70/30 using twin-screw extrusion. The composite rods containing 0, 20, 30, 40 and 50 wt% of bioactive glass were further self-reinforced by drawing to a diameter of approxim...

journal_title：Acta biomaterialia

authors： Niemelä T,Niiranen H,Kellomäki M,Törmälä P

更新日期：2005-03-01 00:00:00

abstract：:Tissue-derived extracellular matrix (ECM) biomaterials to regenerate the meniscus have gained increasing attention in treating meniscus injuries and diseases, particularly for aged persons and athletes. However, ECM scaffold has poor cell infiltration and can only be implanted using surgical procedures. To overcome th...

journal_title：Acta biomaterialia

authors： Wu J,Ding Q,Dutta A,Wang Y,Huang YH,Weng H,Tang L,Hong Y

更新日期：2015-04-01 00:00:00

abstract：:Dental-derived mesenchymal stem cells (MSCs) are promising candidates for cartilage regeneration, with a high capacity for chondrogenic differentiation. This property helps make dental MSCs an advantageous therapeutic option compared to current treatment modalities. The MSC delivery vehicle is the principal determinan...

journal_title：Acta biomaterialia

authors： Moshaverinia A,Xu X,Chen C,Akiyama K,Snead ML,Shi S

更新日期：2013-12-01 00:00:00

abstract：:Anisotropic scaffolds with the typical structure of lamellar, aligned and continuous pores were successfully achieved by the directional solidification of water-based β-tricalcium phosphate (β-TCP) suspensions. Adjustable porosities from 49 to 82%, tunable pore widths from 8 to 50μm and linked ceramic cells with wall ...

journal_title：Acta biomaterialia

authors： Flauder S,Gbureck U,Müller FA

更新日期：2014-12-01 00:00:00

abstract：:To search for potential non-viral nucleic acids carriers, a series of novel cationic polymers, multi-armed poly(aspartate-graft-oligoethylenimine) (MP-g-OEI) copolymers were designed and synthesized by grafting different types of oligoethylenimine (OEI) to a multi-armed poly(l-aspartic acid) backbone. The as-synthesiz...

journal_title：Acta biomaterialia

authors： Dong X,Lin L,Chen J,Tian H,Xiao C,Guo Z,Li Y,Wei Y,Chen X

更新日期：2013-06-01 00:00:00

abstract：:Corneal collagen cross-linking (CXL) treatment can restore vision in patients suffering from keratoconus and corneal injury, by improving the mechanical properties of the cornea. The correlation between ultraviolet-A (UVA) irradiant energies of standard CXL (SCXL) and corneal visco-hyperelastic mechanical behavior rem...

journal_title：Acta biomaterialia

authors： Liu T,Shen M,Li H,Zhang Y,Mu B,Zhao X,Wang Y

更新日期：2020-09-01 00:00:00

abstract：:An important aim of bone regenerative medicine is to design biomaterials with controlled chemical and topographical features to guide stem cell fate towards osteoblasts without addition of specific osteogenic factors. Herein, we find that sprayed bioactive and biocompatible calcium phosphate substrates (CaP) with cont...

journal_title：Acta biomaterialia

authors： Mechiche Alami S,Rammal H,Boulagnon-Rombi C,Velard F,Lazar F,Drevet R,Laurent Maquin D,Gangloff SC,Hemmerlé J,Voegel JC,Francius G,Schaaf P,Boulmedais F,Kerdjoudj H

更新日期：2017-02-01 00:00:00

abstract：:We have performed a comparative analysis of glutaraldehyde-preserved ostrich pericardium, as a novel biomaterial, with bovine pericardium. The biochemical characteristics (histology, water content, amino acid composition, and collagen and elastin contents), mechanical properties, and in vivo calcification in a subcuta...

journal_title：Acta biomaterialia

authors： Maestro MM,Turnay J,Olmo N,Fernández P,Suárez D,García Páez JM,Urillo S,Lizarbe MA,Jorge-Herrero E

更新日期：2006-03-01 00:00:00

abstract：:The aim of the present study was to evaluate the biological properties of a collagen-phospholipid polymer hybrid gel (MiC30 gel) designed for use as a tissue membrane. The following four types of collagen gels were synthesized and tested in vitro and in vivo: physically cross-linked collagen gel (Uc gel), N-(3-dimethy...

journal_title：Acta biomaterialia

authors： Nam K,Kimura T,Funamoto S,Kishida A

更新日期：2010-02-01 00:00:00

abstract：:A pH-sensitive copolymer PAsp(DIP)-b-PAsp(MEA) (PDPM) was synthesized and self-assembled to micelle loading chemotherapeutic drug doxorubicin (DOX) and introducing a gold nanocage structure for photothermo-chemotherapy and photoacoustic imaging. After further surface modification with polyethylene glycol (PEG), the DO...

journal_title：Acta biomaterialia

authors： Zhou G,Xiao H,Li X,Huang Y,Song W,Song L,Chen M,Cheng D,Shuai X

更新日期：2017-12-01 00:00:00

abstract：UNLABELLED:Recently, photodynamic therapy (PDT) is one of the new clinical options by generating cytotoxic reactive oxygen species (ROS) to kill cancer cells. However, the optical approach of PDT is limited by tissue penetration depth of visible light. In this study, we propose that a ROS-enhanced nanoparticle, hafnium...

journal_title：Acta biomaterialia

authors： Chen MH,Hanagata N,Ikoma T,Huang JY,Li KY,Lin CP,Lin FH

更新日期：2016-06-01 00:00:00

abstract：:Three dimensional (3D) printing is highly amenable to the fabrication of tissue-engineered organs of a repetitive microstructure such as the liver. The creation of uniform and geometrically repetitive tissue scaffolds can also allow for the control over cellular aggregation and nutrient diffusion. However, the effect ...

journal_title：Acta biomaterialia

authors： Lewis PL,Green RM,Shah RN

更新日期：2018-03-15 00:00:00

abstract：:This paper presents an experimental investigation and evidence of rate-dependency in the planar mechanical behaviour of semilunar heart valves. Samples of porcine aortic and pulmonary valves were subjected to biaxial deformations across 1000-fold stretch rate, ranging from λ̇=0.001 to 1 s-1. The experimental campaign ...

journal_title：Acta biomaterialia

authors： Anssari-Benam A,Tseng YT,Holzapfel GA,Bucchi A

更新日期：2019-04-01 00:00:00

abstract：:A critical challenge to regenerating close mimics of native axonal pathways under chronic neurodegenerative disease or injury conditions is the inability to stimulate, sustain and steer neurite outgrowth over a long distance, until they reach their intended targets. Understanding neurite outgrowth necessitates quantit...

journal_title：Acta biomaterialia

authors： Kothapalli CR,Honarmandi P

更新日期：2014-08-01 00:00:00

abstract：:We developed a calcium phosphate-based paste containing siRNA against TNF-α and investigated its anti-inflammatory and bone-healing effects in vitro and in vivo in a rat periodontitis model. The bioactive spherical CaP/PEI/siRNA/SiO2 nanoparticles had a core diameter of 40-90 nm and a positive charge (+23 mV) that fac...

journal_title：Acta biomaterialia

authors： Tenkumo T,Rojas-Sánchez L,Vanegas Sáenz JR,Ogawa T,Miyashita M,Yoda N,Prymak O,Sokolova V,Sasaki K,Epple M

更新日期：2020-03-15 00:00:00

abstract：:Mesoporous materials are of high interest as implant coatings to receive an enhanced osseointegration. In this study, titanium implants coated with mesoporous TiO(2) thin films have been evaluated both in vitro and in vivo. Material characterization showed that, with partly crystalline TiO(2) (anatase), long-range-ord...

journal_title：Acta biomaterialia

authors： Karlsson J,Jimbo R,Fathali HM,Schwartz-Filho HO,Hayashi M,Halvarsson M,Wennerberg A,Andersson M

更新日期：2012-12-01 00:00:00

abstract：:Podophyllotoxin (PPT) is a chemotherapeutic agent which has shown significant activity against P-glycoprotein (P-gp) mediated multi drug resistant cancer cells. However, because of the poor aqueous solubility and high toxicity, PPT cannot be used in clinical cancer therapy. In order to enhance the efficiency and reduc...

journal_title：Acta biomaterialia

authors： Zhou H,Lv S,Zhang D,Deng M,Zhang X,Tang Z,Chen X

更新日期：2018-06-01 00:00:00