Epigenetic modifiers promote efficient generation of neural-like cells from bone marrow-derived mesenchymal cells grown in neural environment.

abstract：:Adipose-derived mesenchymal stromal cells (ADSCs) exhibited high potential in tissue repair and regeneration, and it has been proved that ADSCs could protect brain cells from apoptosis and maintaining blood-brain barrier stability after cerebral vascular disease. In this study, we evaluated the therapeutic potential a...

journal_title：Journal of cellular biochemistry

authors： Zhang Y,Deng H,Hu Y,Pan C,Wu G,Li Q,Tang Z

更新日期：2019-09-01 00:00:00

abstract：:Hantavirus infections are now recognized to be a global problem. The hantaviruses include several genotypic variants of the virus with different distributions in varying geographical regions. The virus genotypes seem to segregate in association with certain manifestations specific for each syndrome. They primarily inc...

journal_title：Journal of cellular biochemistry

authors： Kalaiselvan S,Sankar S,Ramamurthy M,Ghosh AR,Nandagopal B,Sridharan G

更新日期：2017-05-01 00:00:00

abstract：:This review evaluates the use of temperature-sensitive (ts) mutants to investigate functional molecules in mammalian cells. A series of studies were performed in which mammalian cells expressing functional molecules were isolated from ts mutants using complementation by the introduction and expression of the responsib...

journal_title：Journal of cellular biochemistry

authors： Sugaya K

更新日期：2018-09-01 00:00:00

abstract：:Embryo development block seriously limits the success of in vitro embryo production and assisted reproductive technology. Although numerous researchers have explored this problem, it remains to be solved. In this study, we found that melatonin supplementation at 10-8 and 10-9 M in M16 significantly reduced two-cell bl...

journal_title：Journal of cellular biochemistry

authors： Shi F,Li H,Wang E,Chen ZJ,Zhang C

更新日期：2018-11-01 00:00:00

abstract：:Tumor necrosis factor a (TNFa) is an inflammatory cytokine that plays a crucial role in the immune response and the progression of cervical lesions. There is a growing body of data evaluating the value of a genetic variant in the TNFa gene with the risk of developing cervical cancer. The aim of this study was to explo...

journal_title：Journal of cellular biochemistry

authors： Babapour N,Mehramiz M,Rastgar Moghadam A,Behboodi N,Yousefi Z,Maftouh M,Talebian S,Khazaei M,Jafarian A,Sharifi-Sistani N,Avan A,Hasanzadeh M

更新日期：2019-04-01 00:00:00

abstract：:We investigated the early effects of the anti-idiotypic antibody (clone 1D5), which recognized the estrogen receptor (ER), on cytosolic free calcium concentration ([Ca2+]i) and its long term effects on creatine kinase (CK) specific activity in female human and rat osteoblasts. These actions were compared to the known ...

journal_title：Journal of cellular biochemistry

authors： Sömjen D,Kohen F,Lieberherr M

更新日期：1997-04-01 00:00:00

abstract：:Cultured human melanoma cells were found to secrete TGF-beta mostly in latent biologically inactive form but in addition five of six melanoma cell lines studied produced in conditioned culture medium active TGF-beta in the range from 370 to 610 pg per 10(6) cells per 24 h. A distinct characteristic of these melanoma c...

journal_title：Journal of cellular biochemistry

authors： Bizik J,Felnerova D,Grofova M,Vaheri A

更新日期：1996-07-01 00:00:00

abstract：:1 alpha,25-Dihydroxyvitamin D3 exerts rapid nongenomic effects on rat osteoblast-like cells independent of the classic nuclear receptor. These effects include changes in phospholipid metabolism and cell calcium. Intracellular calcium itself has been proposed to regulate intracellular pH in osteoblast cell lines. The p...

journal_title：Journal of cellular biochemistry

authors： Jenis LG,Lian JB,Stein GS,Baran DT

更新日期：1993-11-01 00:00:00

abstract：:Sonic hedgehog (Shh) is a key signal protein in early embryological patterning of limb bud development. Its analog, Indian hedgehog (Ihh), primarily expressed during early cartilage development in prehypertrophic chondrocytes, regulates proliferation and suppresses terminal differentiation of postnatal growth plate (G...

journal_title：Journal of cellular biochemistry

authors： Wu LN,Lu M,Genge BR,Guo GY,Nie D,Wuthier RE

更新日期：2002-01-01 00:00:00

abstract：:Transplantation of functional insulin-producing cells (IPCs) provides a novel mode for insulin replacement, but is often accompanied by many undesirable side effects. Our previous studies suggested that IPCs could not mimic the physiological regulation of insulin secretion performed by pancreatic beta cells. To obtain...

journal_title：Journal of cellular biochemistry

authors： Shi Q,Luo S,Jia H,Feng L,Lu X,Zhou L,Cai J

更新日期：2013-10-01 00:00:00

abstract：:17β-Estradiol (E2 ) protects several nonreproductive tissues from apoptosis, including skeletal muscle. Previously, we showed that E2 at physiological concentrations prevented apoptosis induced by H2 O2 in skeletal myoblasts, reverting PKCδ, JNK, and p66Shc activation and exerting a beneficial action over mitochondria...

journal_title：Journal of cellular biochemistry

authors： La Colla A,Vasconsuelo A,Milanesi L,Pronsato L

更新日期：2017-01-01 00:00:00

abstract：:This study aimed at elucidating the molecular mechanism of miR-381-3p in cervical cancer progression, which may provide a novel therapeutic target for patients with cervical cancer. The expression of miR-381-3p was confirmed by quantitative reverse transcription polymerase chain reaction. Microarray analysis was condu...

journal_title：Journal of cellular biochemistry

authors： Shang A,Zhou C,Bian G,Chen W,Lu W,Wang W,Li D

更新日期：2019-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) produced by endothelial cells and macrophages play important roles in atherogenesis because they promote the formation of oxidized low-density lipoproteins (oxLDL). Extracellular-superoxide dismutase (EC-SOD) is mainly produced by vascular smooth muscle cells (VSMCs), is secreted into the...

journal_title：Journal of cellular biochemistry

authors： Makino J,Asai R,Hashimoto M,Kamiya T,Hara H,Ninomiya M,Koketsu M,Adachi T

更新日期：2016-11-01 00:00:00

abstract：:Chylomicrons play a role in atherosclerosis, however, because the mechanisms involved in the cell uptake of these particles are not fully understood, investigations were carried out using a radioactively labeled protein-free triacylglycerol-rich emulsion incubated with peritoneal macrophages obtained from normal and a...

journal_title：Journal of cellular biochemistry

authors： Carvalho MD,Harada LM,Gidlund M,Ketelhuth DF,Boschcov P,Quintão EC

更新日期：2002-01-01 00:00:00

abstract：:"microRNA-383 suppresses the PI3K-AKT-MTOR signaling pathway to inhibit development of cervical cancer via downregulating PARP2," by Peng Teng, Yan Jiao, Min Hao, Xin Tang, J Cell Biochem. 2018; 5243-5252: The above article, published online on 13 December 2017 in Wiley Online Library (https://onlinelibrary.wiley.com/...

journal_title：Journal of cellular biochemistry

authors：

更新日期：2021-01-01 00:00:00

abstract：:Our previous study demonstrate that vitamin D3 induces the binding of vitamin D3 receptor (VDR) to Sp1 transcription factor and stimulates p27Kip1 expression via the Sp1 consensus sequences in the promoter. Both VDR and Sp1 are transcriptional activators, it is unclear which protein functions as the transcription comp...

journal_title：Journal of cellular biochemistry

authors： Cheng HT,Chen JY,Huang YC,Chang HC,Hung WC

更新日期：2006-08-15 00:00:00

abstract：:Diabetes mellitus is a metabolic disorder characterized by hyperglycemia. We investigated the effect of a prior 30 days voluntary exercise protocol on STZ-diabetic CF1 mice. Glycemia, and the liver and skeletal muscle glycogen, mitochondrial function, and redox status were analyzed up to 5 days after STZ injection. An...

journal_title：Journal of cellular biochemistry

authors： de Carvalho AK,da Silva S,Serafini E,de Souza DR,Farias HR,de Bem Silveira G,Silveira PC,de Souza CT,Portela LV,Muller AP

更新日期：2017-04-01 00:00:00

abstract：:A wide variety of environmental stimuli induce the expression of stress response genes, including high temperatures, hypoxia, heavy metal ions, and amino acid analogs. Stress genes are also induced by low frequency magnetic fields. The cellular response to magnetic fields is activated by unusually weak stimuli, and in...

journal_title：Journal of cellular biochemistry

authors： Blank M,Goodman R

更新日期：1999-12-01 00:00:00

abstract：:Hyaluronan (HA) is a ubiquitous component of the extracellular matrix (ECM) and occurs transiently in both the cell nucleus and cytoplasm. It has been shown to promote cell motility, adhesion, and proliferation and thus it has an important role in such processes as morphogenesis, wound repair, inflammation, and metast...

journal_title：Journal of cellular biochemistry

authors： Entwistle J,Hall CL,Turley EA

更新日期：1996-06-15 00:00:00

abstract：:Occupational exposure to nickel has been epidemiologically linked to increased cancer risk in the respiratory tract. Nickel-induced cell transformation is associated with both genotoxic and epigenetic mechanisms that are poorly understood. Prolidase [E.C.3.4.13.9] is a cytosolic Mn(II)-activated metalloproteinase that...

journal_title：Journal of cellular biochemistry

authors： Miltyk W,Surazynski A,Kasprzak KS,Fivash MJ Jr,Buzard GS,Phang JM

更新日期：2005-04-15 00:00:00

abstract：:Enzymes from natural sources protect the environment via complex biological mechanisms, which aid in reductive immobilization of toxic metals including chromium. Nevertheless, progress was being made in elucidating high-resolution crystal structures of reductases and their binding with flavin mononucleotide (FMN) to u...

journal_title：Journal of cellular biochemistry

authors： Pradhan SK,Singh NR,Dehury B,Panda D,Modi MK,Thatoi H

更新日期：2019-10-01 00:00:00

abstract：:Cell-penetrating peptides (CPPs) are used to transport peptides, proteins, different types of ribonucleic acids (or mimics of these molecules), and DNA into live cells, both plant and mammalian. Leishmania belongs to the class of protozoa having, in comparison to mammalian cells, a different lipid composition of the m...

journal_title：Journal of cellular biochemistry

authors： Keller AA,Breitling R,Hemmerich P,Kappe K,Braun M,Wittig B,Schaefer B,Lorkowski S,Reissmann S

更新日期：2014-02-01 00:00:00

abstract：:The F1F0 ATP synthase has recently become the focus of anti-cancer research. It was once thought that ATP synthases were located strictly on the inner mitochondrial membrane; however, in 1994, it was found that some ATP synthases localized to the cell surface. The cell surface ATP synthases are involved in angiogenesi...

journal_title：Journal of cellular biochemistry

authors： Wang WJ,Shi XX,Liu YW,He YQ,Wang YZ,Yang CX,Gao F

更新日期：2013-07-01 00:00:00

abstract：:The effects of serum on inositol 1,4,5-trisphosphate (IP3) formation and Ca2+ mobilization in the human submandibular cell line A253 were studied. Exposure of A253 cells to fetal bovine serum (FBS) elicited a 3.3-fold increase in IP3 formation and a concentration-dependent transient increase in cytosolic free Ca2+ con...

journal_title：Journal of cellular biochemistry

authors： Sun X,Mörk AC,Helmke RJ,Martinez JR,Zhang GH

更新日期：1999-06-15 00:00:00

abstract：AIM:To detect the expression and identify the role of Ribosomal protein S15A (RPS15A) in human breast cancer (BC). METHODS:Immunohistochemistry (IHC) was carried out for detecting the levels of RPS15A protein. Quantitative PCR was used to evaluate the mRNA level of RPS15A in one normal breast and three BC cell lines. ...

journal_title：Journal of cellular biochemistry

authors： Kong L,Wei Q,Hu X,Chen L,Li J

更新日期：2020-01-01 00:00:00

abstract：:Gastric cancer (GC) is the fifth most frequent cancer and the third-leading cause of cancer-related death worldwide. It is a highly heterogeneous disease regarding the morphological and molecular viewpoints. Since it is curable in primary stages, early detection could improve the survival rate. Long noncoding RNAs con...

journal_title：Journal of cellular biochemistry

authors： Kangarlouei R,Irani S,Noormohammadi Z,Memari F,Mirfakhraie R

更新日期：2019-08-01 00:00:00

abstract：:The current study aimed to explore the functions and roles of microRNA-193b (miR-193b) in the myocardium with ischemia-reperfusion (I/R) injury and a potential therapeutic method for myocardial I/R injury. The mice were subjected to myocardial I/R with or without miR-193b pretreatment. The infarct size and myocardial ...

journal_title：Journal of cellular biochemistry

authors： Zhang J,Niu J,Tian B,Zhao M

更新日期：2019-08-01 00:00:00

abstract：:Several independent assay procedures were used to estimate the activities of the enzyme constituents of the phosphoenolpyruvate-sugar phosphotransferase system (PTS) in osmotically shocked bacterial membrane vesicles. The soluble enzymes of the system were found to be in association with the membrane by several criter...

journal_title：Journal of cellular biochemistry

authors： Saier MH Jr,Cox DF,Feucht BU,Novotny MJ

更新日期：1982-01-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) areinvolvedin a variety of biological processes. In silkworm, numerous lncRNAs have been predicted through deep transcriptome sequencing, but no functional role has been experimentally validated yet. Here, we characterized a new lncRNA iab-1 that was mainly encoded by the intergenic regio...

journal_title：Journal of cellular biochemistry

authors： Wang H,Hu H,Xiang Z,Lu C,Dai F,Tong X

更新日期：2019-10-01 00:00:00

abstract：:Immortalization is an early and essential step of human carcinogenesis which is associated with alterations in gene expression and regulation. Suppression subtractive hybridization (SSH) was successfully performed to identify immortalization-associated genes upregulated in SV40-immortalized lung fibroblasts. We identi...

journal_title：Journal of cellular biochemistry

authors： Jung HM,Choi SJ,Kim JK

更新日期：2009-03-01 00:00:00