Expression profiles of SV40-immortalization-associated genes upregulated in various human cancers.

abstract：BACKGROUND:The impact of aberrant expression of miRNAs, small noncoding RNAs of 19 to 23 nucleotide, has been reported in different types of cancer, such as breast cancer. Authors aim to investigate the role of circulating miRNA-335 as a diagnostic and prognostic marker for breast cancer. MATERIALS AND METHODS:miRNA-3...

journal_title：Journal of cellular biochemistry

authors： Swellam M,Mahmoud MS,Hashim M,Hassan NM,Sobeih ME,Nageeb AM

更新日期：2019-06-01 00:00:00

abstract：:Mycobacterium tuberculosis (Mtb) infects millions of people each year. These bacilli can survive inside macrophages. To favor their survival, pathogen alters various signal transduction pathways in host cells. Phospholipase C (PLC) signaling regulates various processes in mammalian cells but has never been investigate...

journal_title：Journal of cellular biochemistry

authors： Paroha R,Chaurasiya SK,Chourasia R

更新日期：2019-04-01 00:00:00

abstract：:Previously we have shown that transforming growth factor beta (TGF beta) 1, basic fibroblast growth factor (FGF), and platelet-derived growth factor (PDGF) BB inhibit the synthesis of insulin-like growth factor (IGF) II, but their effects on IGF binding protein (IGFBP)-6 in osteoblast cultures are not known. IGFBP-6 b...

journal_title：Journal of cellular biochemistry

authors： Gabbitas B,Canalis E

更新日期：1997-07-01 00:00:00

abstract：:We have recently demonstrated that transforming growth factor (TGF)-beta 1 and TGF-beta 2 are potent inhibitors of the growth and differentiation of murine and human hematopoietic cells. The proliferation of primary unfractionated murine bone marrow by interleukin-3 (IL-3) and human bone marrow by IL-3 or granulocyte/...

journal_title：Journal of cellular biochemistry

authors： Keller JR,Sing GK,Ellingsworth LR,Ruscetti FW

更新日期：1989-02-01 00:00:00

abstract：:Long noncoding RNA (lncRNA) PTCSC3 (hereafter PTCSC3 is used to represent lncRNA PTCSC3) inhibits glioma and thyroid cancer, indicating its potential tumor suppression function in other types of cancers. We explored the potential involvement of PTCSC3 in triple-negative breast cancer (TNBC). In the current study, we f...

journal_title：Journal of cellular biochemistry

authors： Wang N,Hou M,Zhan Y,Sheng X

更新日期：2019-09-01 00:00:00

abstract：:Vascularization is essential for bone development, fracture healing, and bone tissue engineering. We have previously described that coculture of primary human osteoblasts (hOBs) and human umbilical vein endothelial cells (HUVECs) improves differentiation of both cell types. Investigating the role of microRNAs (miRNAs)...

journal_title：Journal of cellular biochemistry

authors： Strassburg S,Nabar N,Lampert F,Goerke SM,Pfeifer D,Finkenzeller G,Stark GB,Simunovic F

更新日期：2017-07-01 00:00:00

abstract：:Overweight and obesity are established factors underpin several metabolic impairments, including the cardiovascular. Although the diversity of factors involved in overweight/obesity-induced cardiovascular diseases, mitochondria has been highlighted due to its role in cardiac metabolism. As obesity can be originated in...

journal_title：Journal of cellular biochemistry

authors： de Moura Freitas C,Nascimento LCPD,Braz GRF,Andrade-Silva SC,Lima-Junior NC,de Araujo Silva T,Fernandes MP,Ferreira DJS,Lagranha CJ

更新日期：2018-10-28 00:00:00

abstract：:Chronic inflammation is a contributing factor to overall cancer risk as well as cancer promotion and progression; however, pathways regulating onset of cancer-promoting inflammatory responses are still poorly understood. Clinical data suggest that deficient anti-tumor cell-mediated immunity, in combination with enhanc...

journal_title：Journal of cellular biochemistry

authors： Johansson M,Tan T,de Visser KE,Coussens LM

更新日期：2007-07-01 00:00:00

abstract：:We investigated activity and mechanism of action of two AhR ligand antitumor agents, AFP 464 and 5F 203 on human renal cancer cells, specifically examining their effects on cell cycle progression, apoptosis, and migration. TK-10, SN12C, Caki-1, and ACHN human renal cancer cell lines were treated with AFP 464 and 5F 20...

journal_title：Journal of cellular biochemistry

authors： Luzzani GA,Callero MA,Kuruppu AI,Trapani V,Flumian C,Todaro L,Bradshaw TD,Loaiza Perez AI

更新日期：2017-12-01 00:00:00

abstract：:We studied how deficiency in lamins A/C and lamina-associated polypeptide 2α (Lap2α) affects DNA repair after irradiation. A-type lamins and Lap2α were not recruited to local DNA lesions and did not accumulate to γ-irradiation-induced foci (IRIF), as it is generally observed for well-known marker of DNA lesions, 53BP1...

journal_title：Journal of cellular biochemistry

authors： Bártová E,Legartová S,Krejčí J,Řezníčková P,Kovaříková AS,Suchánková J,Fedr R,Smirnov E,Hornáček M,Raška I

更新日期：2018-11-01 00:00:00

abstract：:We have previously demonstrated that hydrogen peroxide (H(2)O(2)) treatment of murine 70Z/3 pre-B lymphocytes inhibits the immune response to lipopolysaccharide by attenuating signaling through c-Jun N-terminal kinase (JNK) activation. In the present study, we further examined the signaling intermediates responsible f...

journal_title：Journal of cellular biochemistry

authors： Lee M,Koh WS

更新日期：2003-02-15 00:00:00

abstract：:The myelin basic protein (MBP)-phosphorylating enzymes present during maturation and early embryogenesis of the sea star (Pisaster ochraceus) were investigated. The major maturation-activated MBP kinase (p45 Mapk) was molecularly cloned based on tryptic sequence information obtained with the purified enzyme and shown ...

journal_title：Journal of cellular biochemistry

authors： Lefebvre DL,Charest DL,Yee A,Crawford BJ,Pelech SL

更新日期：1999-11-01 00:00:00

abstract：:Adamts17 is a member of a family of secreted metalloproteinases. In this report, we show that knockdown of Adamts17 expression induces apoptosis and inhibits breast cancer cell growth. Adamts17 expression can rapidly be induced by estrogens. siRNA knockdown of Sp1 or Myc demonstrated that Sp1 is required to induce Ada...

journal_title：Journal of cellular biochemistry

authors： Jia Z,Gao S,M'Rabet N,De Geyter C,Zhang H

更新日期：2014-10-01 00:00:00

abstract：:Relatively little information exists on the ultimate molecular mechanisms by which the lipogenic enzyme Fatty Acid Synthase (FAS) is differentially overexpressed in a biologically aggressive subset of human malignancies. Since the microenvironment of solid tumors contains regions of poor oxygenation and high acidity, ...

journal_title：Journal of cellular biochemistry

authors： Menendez JA,Decker JP,Lupu R

更新日期：2005-01-01 00:00:00

abstract：:This study aims to explore how microRNA-133a (miR-133a) affects cell apoptosis and radio-sensitivity by targeting EGFR via regulating MEK/ERK pathway in esophageal cancer (EC). A total of 358 EC patients were selected and assigned into the resistant and sensitive groups. Human EC KYSE 150 cell line was assigned into t...

journal_title：Journal of cellular biochemistry

authors： Yang QS,Jiang LP,He CY,Tong YN,Liu YY

更新日期：2017-09-01 00:00:00

abstract：:The hypothesis that intercellular adhesion can be subdivided into two separable phenomena, an initial recognition event and a subsequent stabilization, is supported by the use of a new cell binding assay that provides a quantitative measure of intercellular binding strengths. Radioactive single cells are brought into ...

journal_title：Journal of cellular biochemistry

authors： McClay DR,Marchase RB

更新日期：1982-01-01 00:00:00

abstract：:Serous ovarian cancer (SOC) is the most common form of the histological subtype of epithelial ovarian cancer, with the worst clinical outcome. Despite improvements in surgery and chemotherapy, most patients with SOC experience recurrence within 12-18 months of first-line treatment. Current studies are unable to robust...

journal_title：Journal of cellular biochemistry

authors： Deng K,Zhang F,Song W,Zhao W,Rong Z,Cai Y,Xu H,Lu M,Wang W,Li A,Hou Y,Li Z,Li K

更新日期：2018-11-01 00:00:00

abstract：:Lysozyme (LYZ) c-like proteins are primarily present in the testis and epididymis of male reproductive tissues. Here, we report a novel member of the c-type LYZ family, the seminal vesicle-secreted LYZ c-like protein (SVLLP). Three forms of SVLLP were purified from mouse seminal vesicle secretions and characterized as...

journal_title：Journal of cellular biochemistry

authors： Ou CM,Lee RK,Lin MH,Lu CH,Yang TH,Yeh LY,Tsai PJ,Li SH

更新日期：2021-01-19 00:00:00

abstract：:In the last 20 years, more than 1,500 gene therapy clinical trials have been approved worldwide targeting a variety of indications, from inherited monogenic diseases to acquired conditions such as cancer, cardiovascular and infectious diseases. However, concerns about the safety and efficacy of gene therapy pharmaceut...

journal_title：Journal of cellular biochemistry

authors： Coutu DL,Yousefi AM,Galipeau J

更新日期：2009-10-15 00:00:00

abstract：:This review evaluates the use of temperature-sensitive (ts) mutants to investigate functional molecules in mammalian cells. A series of studies were performed in which mammalian cells expressing functional molecules were isolated from ts mutants using complementation by the introduction and expression of the responsib...

journal_title：Journal of cellular biochemistry

authors： Sugaya K

更新日期：2018-09-01 00:00:00

abstract：:Angiogenesis, the formation of new capillary blood vessels, occurs almost exclusively in the microcirculation. This process is controlled by the interaction between factors with positive and negative regulatory activity. In this study, we have compared the effect of two well described positive regulators, vascular end...

journal_title：Journal of cellular biochemistry

authors： Cavallaro U,Tenan M,Castelli V,Perilli A,Maggiano N,Van Meir EG,Montesano R,Soria MR,Pepper MS

更新日期：2001-01-01 00:00:00

abstract：:The human undifferentiated histiocytic cell-line U937 can be induced to differentiate by incubation with 12-0-tetradecanoylphorbol-13-acetate (TPA) into macrophage-like cells. Dexamethasone reduced the prostaglandin production in TPA-differentiated U937 cells dose dependently, whereas undifferentiated U937 cells were ...

journal_title：Journal of cellular biochemistry

authors： Koehler L,Hass R,Goppelt-Struebe M,Kaever V,Resch K

更新日期：1989-07-01 00:00:00

abstract：:This study aims to explore the effect of miR-330 targeting VAV1 on amyloid β-protein (Aβ) production, oxidative stress (OS), and mitochondrial dysfunction in Alzheimer's disease (AD) mice through the MAPK signaling pathway. Putative targeted gene of miR-330 was performed by a miRNA target prediction website and dual-l...

journal_title：Journal of cellular biochemistry

authors： Zhou Y,Wang ZF,Li W,Hong H,Chen J,Tian Y,Liu ZY

更新日期：2018-07-01 00:00:00

abstract：:Excitatory amino acids (EAAs) are found present in the nervous and reproductive systems of animals. Numerous studies have demonstrated a regulatory role for Glutamate (Glu), d-aspartate ( d-Asp) and N-methyl- d-aspartate (NMDA) in the control of spermatogenesis. EAAs are able to stimulate the Glutamate receptors, incl...

journal_title：Journal of cellular biochemistry

authors： Santillo A,Falvo S,Di Fiore MM,Di Giacomo Russo F,Chieffi P,Usiello A,Pinelli C,Baccari GC

更新日期：2019-02-14 00:00:00

abstract：:Osteosarcoma (OS) is a highly aggressive bone tumor with a poor prognosis. MicroRNAs are revealed to exerts essential roles in the carcinogenesis and tumor invasion of OS. But, the function of miR-1296-5p and its related mechanism in OS progression have not yet been studied. This study discovered the levels of miR-129...

journal_title：Journal of cellular biochemistry

authors： Wang L,Hu K,Chao Y,Wang X

更新日期：2020-02-01 00:00:00

abstract：:Breast cancer remains the major cause of cancer-related deaths in women world-wide. The heterogeneity of breast cancer has further complicated the progress of target-based therapies. Triple negative breast cancers, lacking estrogen receptor, progesterone receptor and the Her-2/neu (ErbB2), represent a highly aggressiv...

journal_title：Journal of cellular biochemistry

authors： Ahmad A,Banerjee S,Wang Z,Kong D,Sarkar FH

更新日期：2008-12-15 00:00:00

abstract：:To ascertain whether p53 deficiency in vivo leads to the deregulation of DNA methylation machinery prior to tumor development, we investigated the expression profile of DNA methyltransferases in the thymus and the liver of p53(+/+), p53(+/-), and p53(-/-) mice at 7 weeks of age before tumor development. The expression...

journal_title：Journal of cellular biochemistry

authors： Park IY,Sohn BH,Choo JH,Joe CO,Seong JK,Lee YI,Chung JH

更新日期：2005-02-15 00:00:00

abstract：:Four detergents have been compared for identification of the Plasmodium knowlesi variant antigen on infected erythrocytes by immunoprecipitation analysis. Erythrocytes infected with late trophozoite and schizont forms of cloned asexual parasites were labeled by lactoperoxidase-catalyzed radioiodination and extracted e...

journal_title：Journal of cellular biochemistry

authors： Howard RJ,Barnwell JW

更新日期：1984-01-01 00:00:00

abstract：:Perilipin and ADRP, located on the surface of intracellular lipid droplets, are proposed to be involved in adipocyte lipid metabolism. The aim of the present study was to investigate the effect of PKA and PKC activities on the distribution of perilipin and ADRP in primary cultured adrenal cells, and the role of ERK in...

journal_title：Journal of cellular biochemistry

authors： Fong TH,Yang CC,Greenberg AS,Wang SM

更新日期：2002-01-01 00:00:00

abstract：:The cardiomyocyte differentiation from mouse embryonic stem cells (mESCs) is a dynamic and complex process that involved in the precision regulation of histone acetylation. The formation of action potential (AP) in mature cardiomyocytes is based on the expression pattern of Na+ , Ca2+ , and K+ ion channels, in which t...

journal_title：Journal of cellular biochemistry

authors： Wang D,Liu C,Li Z,Wang Y,Wang W,Wu X,Wang K,Miao W,Li L,Peng L

更新日期：2017-12-01 00:00:00