A mouse seminal vesicle-secreted lysozyme c-like protein modulates sperm capacitation.

abstract：:Human prostatic carcinoma frequently metastasizes to bone tissue and activates bone metabolism, especially bone formation, at the site of metastasis. It has been reported that an extract of prostatic carcinoma and conditioned medium (CM) of a human prostatic carcinoma cell line, PC-3, established from a bone metastast...

journal_title：Journal of cellular biochemistry

authors： Kido J,Yamauchi N,Ohishi K,Kataoka M,Nishikawa S,Nakamura T,Kadono H,Ikedo D,Ueno A,Nonomura N,Okuyama A,Nagata T

更新日期：1997-11-01 00:00:00

abstract：:Skin epidermis is a constantly renewing epithelium that is composed of various cell types and provides an ideal model system for tissue regeneration and heterogeneity studies. Integrins are a family of transmembrane receptors that mediate cell adhesion in the epidermis, and integrin expression spatially reflects epide...

journal_title：Journal of cellular biochemistry

authors： He W,Ye J,Xu H,Lin Y,Zheng Y

更新日期：2020-03-01 00:00:00

abstract：:HSP90 chaperones are transducer proteins of many signaling pathways in cells. Using a highly specific inhibitor, geldanamycin (GA), an increasing number of the HSP90 client proteins have been identified. Nevertheless, there is little information on the differential transactivation of the two isoforms of the hsp90 gene...

journal_title：Journal of cellular biochemistry

authors： Chao CC,Sun FC,Wang CH,Lo CW,Chang YS,Chang KC,Chang MD,Lai YK

更新日期：2008-07-01 00:00:00

abstract：:This study investigates the effect of nuclear factor erythroid 2-related factor 2-antioxidant response element (Nrf2-ARE) signaling pathway in vascular calcification (VC) via inducing Autophagy in renal vascular smooth muscle cells (VSMCs). VSMCs were assigned into six experimental groups: the normal control, high pho...

journal_title：Journal of cellular biochemistry

authors： Yao L,Wang J,Tian BY,Xu TH,Sheng ZT

更新日期：2017-12-01 00:00:00

abstract：:Stimulation of osteoblast survival signals may be an important mechanism of regulating bone anabolism. Protein kinase B (PKB/Akt), a serine-threonine protein kinase, is a critical regulator of normal cell growth, cell cycle progression, and cell survival. In this study we have investigated the signaling pathways activ...

journal_title：Journal of cellular biochemistry

authors： Chaudhary LR,Hruska KA

更新日期：2001-03-26 00:00:00

abstract：:The 25-hydroxyvitamin D(3)-24-hydroxylase mRNA is tightly and reciprocally regulated by 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) and parathyroid hormone (PTH). The upregulation of the 24-hydroxylase by 1,25(OH)(2)D(3) is well established and occurs at the transcriptional level through two vitamin D response elemen...

journal_title：Journal of cellular biochemistry

authors： Zierold C,Mings JA,DeLuca HF

更新日期：2003-02-01 00:00:00

abstract：:Osteoporosis (OP) is a multifactorial and common bone disease worldwide. The clinical diagnosis and treatment of osteoporosis has limitations since changes in bone density occur slightly. Thus, it is critically needed to look for new biomarkers to identify and cure osteoporosis. CircRNAs are important molecular regula...

journal_title：Journal of cellular biochemistry

authors： Huang Y,Xie J,Li E

更新日期：2019-09-01 00:00:00

abstract：:Alpha-fetoprotein (AFP) is one of the major serum proteins in the early life of mammals. We have previously identified a novel cis-acting element designated as DAS at the 5'-flanking region of the AFP gene and demonstrated that the DAS sequence can be specifically recognized by nuclear protein DAP-II in AFP-producing ...

journal_title：Journal of cellular biochemistry

authors： Jiao R,He QY,Chen H,Hua Z,Jiao Q,Chiu JF

更新日期：2006-08-01 00:00:00

abstract：:We have recently described the isolation and purification to homogeneity of a new sialoglycopeptide from bovine brain cell surfaces that reversibly inhibits protein synthesis and DNA synthesis of normal but not transformed cells. Active inhibitory preparations, however, were shown to contain a protease activity that w...

journal_title：Journal of cellular biochemistry

authors： Sharifi BG,Bascom CC,Fattaey H,Nash S,Johnson TC

更新日期：1986-01-01 00:00:00

abstract：:Mounting evidence showed that microRNAs involve in development and chemoresistance of various human cancers. We explored the roles and mechanisms of miR-144 in resistance to cisplatin (CDDP) of cervical cancer cells. miR-144 and LIM homeobox 2 (LHX2) expression in CDDP-resistant and the parental cells was determined b...

journal_title：Journal of cellular biochemistry

authors： Shi F,Su J,Liu Z,Wang J,Wang T

更新日期：2019-09-01 00:00:00

abstract：:The promoter of the mouse thymidylate synthase (TS) gene lacks a TATAA box and an initiator element, is bidirectional and initiates transcription at multiple start sites across broad initiation windows upstream and downstream of the 30 nt essential promoter region. The TS promoter also plays an essential role in the p...

journal_title：Journal of cellular biochemistry

authors： Kapadia F,Johnson LF

更新日期：2006-02-15 00:00:00

abstract：:Pancreatic stellate cells (PSCs) secrete various factors, which can influence the β-cell function. The identification of stellate cell infiltration into the islets in pancreatic diseases suggests possible existence of cross-talk between these cells. To elucidate the influence of PSCs on β-cell function, mouse PSCs wer...

journal_title：Journal of cellular biochemistry

authors： Bynigeri RR,Mitnala S,Talukdar R,Singh SS,Duvvuru NR

更新日期：2020-01-01 00:00:00

abstract：:Adult human mesenchymal stem cells (MSCs) hold promise for an increasing list of therapeutic uses due to their ease of isolation, expansion, and multi-lineage differentiation potential. To maximize the clinical potential of MSCs, the underlying mechanisms by which MSC functionality is controlled must be understood. We...

journal_title：Journal of cellular biochemistry

authors： Pricola KL,Kuhn NZ,Haleem-Smith H,Song Y,Tuan RS

更新日期：2009-10-15 00:00:00

abstract：:Understanding how the information is conveyed from outside to inside the cell is a critical challenge for all biologists involved in signal transduction. The flow of information initiated by cell-cell and cell-extracellular matrix contacts is mediated by the formation of adhesion complexes involving multiple proteins....

journal_title：Journal of cellular biochemistry

authors： Lelièvre SA,Bissell MJ

更新日期：1998-01-01 00:00:00

abstract：:Osteosarcoma (OS) is the most common primary malignant tumor of the bone with a strong tendency to early metastasis, and occurs in growing bones more commonly in children and adolescents. Considering the limited therapeutic methods and lack of 100% success of these methods, developing innovative therapies with high ef...

journal_title：Journal of cellular biochemistry

authors： Shabani P,Izadpanah S,Aghebati-Maleki A,Baghbani E,Baghbanzadeh A,Fotouhi A,Bakhshinejad B,Aghebati-Maleki L,Baradaran B

更新日期：2019-04-01 00:00:00

abstract：:Neutrophils are essential for host defense and their programmed cell death and removal are critical for the optimal expression as well as for efficient resolution of inflammation. Delayed neutrophil apoptosis or impaired clearance of apoptotic neutrophils by macrophages contributes to the progression of chronic inflam...

journal_title：Journal of cellular biochemistry

authors： Filep JG,El Kebir D

更新日期：2009-12-01 00:00:00

abstract：:Entry of β-elemene into various phases of clinical trials advocates its significance as a premium candidate likely to gain access to mainstream medicine. Based on the insights gleaned from decades of research, it seems increasingly transparent that β-elemene has shown significant ability to modulate multiple cell sign...

journal_title：Journal of cellular biochemistry

authors： Qureshi MZ,Attar R,Romero MA,Sabitaliyevich UY,Nurmurzayevich SB,Ozturk O,Wakim LH,Lin X,Ozbey U,Yelekenova AB,Farooqi AA

更新日期：2019-08-01 00:00:00

abstract：:AT-rich interaction domain 4A (ARID4A) and AT-rich interaction domain 4B (ARID4B), which are both the AT-rich interaction domain (ARID) family, have been reported to be oncogene or tumor suppressor gene in various human malignances, but there is no involvement about their functions in prostate cancer (PCa). Our previo...

journal_title：Journal of cellular biochemistry

authors： Liang YK,Han ZD,Lu JM,Liu ZZ,Zhuo YJ,Zhu XJ,Chen JX,Ye JH,Liang YX,He HC,Zhong WD

更新日期：2018-09-01 00:00:00

abstract：:Reduced insulin receptor protein levels have been reported in the kidney cortex from diabetic humans and animals. We recently reported that, targeted deletion of insulin receptor (IR) from proximal tubules (PT) resulted in hyperglycemia in non-obese mice. To elucidate the mechanism, we examined human proximal tubule c...

journal_title：Journal of cellular biochemistry

authors： Pandey G,Shankar K,Makhija E,Gaikwad A,Ecelbarger C,Mandhani A,Srivastava A,Tiwari S

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Long noncoding RNAs (lncRNAs) regulate gene expression by acting with microRNAs (miRNAs) and indirectly interact with messenger RNA (mRNAs). However, the roles of specific lncRNA and its related competing endogenous RNAs (ceRNA) network in alopecia areata (AA) are not fully understood. METHODS:The blood lnc...

journal_title：Journal of cellular biochemistry

authors： Sheng Y,Ma J,Zhao J,Qi S,Hu R,Yang Q

更新日期：2019-06-01 00:00:00

abstract：:Osteosarcoma (OS) is the most malignant primary bone tumor in children and adolescents with limited treatment options and poor prognosis. Recently, aberrant expression of Runx2 has been found in OS, thereby contributing to the development, and progression of OS. However, the upstream signaling molecules that regulate ...

journal_title：Journal of cellular biochemistry

authors： Liang GH,Liu N,He MT,Yang J,Liang ZJ,Gao XJ,Rahhal AH,He QY,Zhang HT,Zha ZG

更新日期：2018-01-01 00:00:00

abstract：:L-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) are adhesion molecules that play critical roles in neutrophil rolling during inflammation and lymphocyte homing. On the other hand they also function as signaling receptors to induce cytoskeleton changes. The present study is to investigate the signaling kinases...

journal_title：Journal of cellular biochemistry

authors： Luo J,Xu T,Wang X,Ba X,Feng X,Deepak V,Zeng X

更新日期：2010-07-01 00:00:00

abstract：:The expression of receptors belonging to the epidermal growth factor receptor subfamily has been largely studied these last years in epithelial cells mainly as involved in cell proliferation and malignant progression. Although much work has focused on the role of these growth factor receptors in the differentiation of...

journal_title：Journal of cellular biochemistry

authors： Pagano E,Calvo JC

更新日期：2003-10-15 00:00:00

abstract：:Accumulating studies indicates that circular RNAs (circRNAs) play an imperative role in modulating cancer progression and metastasis. In the previous study, elevated circ_0029426 was first observed in glioblastoma (GBM) tissues compared with normal tissues by circRNA microarray. Our aim is to study the function and me...

journal_title：Journal of cellular biochemistry

authors： Zhang G,Sun W,Zhu L,Feng Y,Wu L,Li T

更新日期：2019-06-01 00:00:00

abstract：:This study aimed to address the insufficiency of traditional meta-analysis and provide improved guidelines for the clinical practice of osteosarcoma treatment. The heterogeneity of the fixed-effect model was calculated, and when necessary, a random-effect model was adopted. Furthermore, the direct and indirect evidenc...

journal_title：Journal of cellular biochemistry

authors： Zhang T,Zhang S,Yang F,Wang L,Zhu S,Qiu B,Li S,Deng Z

更新日期：2018-01-01 00:00:00

abstract：:Mechanical loading of bone generates fluid flow within the mineralized matrix that exerts fluid shear stress (FSS) on cells. We examined effects of FSS on receptor activator of nuclear factor kappa B ligand (RANKL), a critical factor for osteoclast formation. Primary murine osteoblasts were subjected to pulsatile FSS ...

journal_title：Journal of cellular biochemistry

authors： Mehrotra M,Saegusa M,Wadhwa S,Voznesensky O,Peterson D,Pilbeam C

更新日期：2006-08-01 00:00:00

abstract：:Adiponectin is an important insulin-sensitizing adipokine with multiple beneficial effects on obesity-associated medical complications. It is secreted from adipocytes into circulation as high, medium, and low molecular weight forms (HMW, MMW, and LMW). Each oligomeric form of adiponectin exerts non-overlapping biologi...

journal_title：Journal of cellular biochemistry

authors： Chen Z,Zhang L,Yi J,Yang Z,Zhang Z,Li Z

更新日期：2012-11-01 00:00:00

abstract：:Burkitt lymphoma (BL) commonly exhibits Epstein-Barr virus (EBV) positivity associated with latent chronic infection. Models of acute EBV infection have been associated with cellular resistance to apoptosis. However, the effect of latent long-term EBV infection on apoptosis induced by drugs is not well defined. To det...

journal_title：Journal of cellular biochemistry

authors： Lima RT,Seca H,Soares P,Nascimento MS,Vasconcelos MH

更新日期：2011-01-01 00:00:00

abstract：:The Wnt signaling pathway has recently been demonstrated to play an important role in bone cell function. In previous studies using DNA microarray analyses, we observed a change in some of the molecular components of the canonical Wnt pathway namely, frizzled-1 (FZD-1) and axil, in response to continuous parathyroid h...

journal_title：Journal of cellular biochemistry

authors： Kulkarni NH,Halladay DL,Miles RR,Gilbert LM,Frolik CA,Galvin RJ,Martin TJ,Gillespie MT,Onyia JE

更新日期：2005-08-15 00:00:00

abstract：:There has been an impressive emergence of mass spectrometry based technologies applied toward the study of proteins. Equally notable is the rapid adaptation of these technologies to biomedical approaches in the realm of clinical proteomics. Concerted efforts toward the elucidation of the proteomes of organ sites or sp...

journal_title：Journal of cellular biochemistry

authors： Semmes OJ,Malik G,Ward M

更新日期：2006-06-01 00:00:00