Digoxin kinetics in the elderly.

abstract：BACKGROUND:Visuo-spatial neglect (VSN) after stroke is associated with a poor prognosis for rehabilitation. The co-existence of a visual field deficit (VFD) with VSN may be associated with impaired visuo-spatial functioning and thereby poor functional outcome. OBJECTIVE:To determine whether the presence of a VFD (i) e...

journal_title：Age and ageing

authors： Cassidy TP,Bruce DW,Lewis S,Gray CS

更新日期：1999-05-01 00:00:00

abstract：INTRODUCTION:a professional man sustained a residual, persisting, isolated impairment of short-term memory secondary to severe carbon monoxide poisoning. Informal, open trial of the cholinesterase inhibitor donepezil resulted in uncertain benefit. PROTOCOL:an N-of-1 randomized, double-blind controlled trial of donepez...

journal_title：Age and ageing

authors： Price JD,Grimley Evans J

更新日期：2002-07-01 00:00:00

abstract：:Postural control is no longer considered simply a summation of static reflexes but, rather, a complex skill based on the interaction of dynamic sensorimotor processes. The two main functional goals of postural behaviour are postural orientation and postural equilibrium. Postural orientation involves the active alignme...

journal_title：Age and ageing

authors： Horak FB

更新日期：2006-09-01 00:00:00

abstract：:Clinical assessments have to be used in epidemiological studies in the absence of more objective means of establishing diagnosis or recording events in the natural history of disease. This requires the standardization of definition, technique and interpretation as a means of reducing observer variability in clinical e...

journal_title：Age and ageing

authors： Garraway WM,Akhtar AJ,Gore SM,Prescott RJ,Smith RG

更新日期：1976-11-01 00:00:00

abstract：:Interleukin-1 mediates the febrile response which is often said to be reduced in the elderly. Interleukin-1 production by monocytes cultured in vitro and stimulated with bacterial lipopolysaccharide was measured. Three groups of subjects were studied; 40 normal young, 33 well elderly and 40 elderly with a history of r...

journal_title：Age and ageing

authors： Rudd AG,Banerjee DK

更新日期：1989-01-01 00:00:00

abstract：:The measurement of cutaneous pain threshold using the Neuromod Selectra Model 7750 Transcutaneous Neuronal Electrical Stimulator is described. Pain threshold, measured in 520 healthy volunteers aged 5-105 years, increased with age. Consistent values were obtained in 22 healthy volunteers on three successive days. Pain...

journal_title：Age and ageing

authors： Tucker MA,Andrew MF,Ogle SJ,Davison JG

更新日期：1989-07-01 00:00:00

abstract：:Brucellosis is the most commonly reported zoonosis. Nervous system participation can occur at any stage of the disease either in acute or subacute or chronic form. Isolated nervous system involvement or neurobrucellosis is a relatively rare form of the disease. We describe an unusual case of an older patient with deme...

journal_title：Age and ageing

authors： Spyrou A,Natsis KS,Papamichalis E,Mourtzinos H

更新日期：2019-07-01 00:00:00

abstract：:Plasma Human Growth Hormone (HGH) was raised in a patient with bronchial carcinoma and hypertrophic pulmonary osteoarthropathy before radiotherapy to the tumour. Though the soft-tissue swelling and pain of hypertrophic osteoarthropathy disappeared two to three weeks after radiotherapy to the carcinoma the HGH plasma l...

journal_title：Age and ageing

authors： Mukherjee SK

更新日期：1975-05-01 00:00:00

abstract：:Visual acuity and contrast sensitivity were measured in 95 residents of a hostel for the aged (mean age = 83 years) using a dual-contrast letter chart and the Melbourne Edge Test (MET). Vision (as measured by visual acuity, the MET, low-contrast visual acuity, and difference between high- and low-contrast acuity) decr...

journal_title：Age and ageing

authors： Lord SR,Clark RD,Webster IW

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:the recognition of stroke symptoms by the public and activation of the emergency medical services (EMS) are the most important factors in instigating pre-hospital stroke care. Studies have suggested that poor recognition of the warning signs of stroke is the main cause of delay in accessing the EMS. METHODS...

journal_title：Age and ageing

authors： Jones SP,Jenkinson AJ,Leathley MJ,Watkins CL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:fifteen percent of patients with Crohn's disease (CD) are elderly; they are less likely to have complications and more likely to have colonic disease. OBJECTIVE:to compare disease behaviour in patients with CD based on age at diagnosis. DESIGN:cross-sectional study. SETTING:tertiary referral centre. SUBJ...

journal_title：Age and ageing

authors： Quezada SM,Steinberger EK,Cross RK

更新日期：2013-01-01 00:00:00

abstract：:Formal assessment of cognitive decline with cognitive tests can be difficult, requiring either two measurement points or a comparison of 'hold' with 'don't hold' tests. Informant-based assessment provides an alternative approach because informants can adopt a longitudinal perspective and directly rate cognitive change...

journal_title：Age and ageing

authors： Jorm AF,Christensen H,Henderson AS,Jacomb PA,Korten AE,Mackinnon A

更新日期：1996-03-01 00:00:00

abstract：:A simple random sample of older people composed of 215 men and 272 women aged 62 years and over was examined in Edinburgh in 1968-9. After one year, 86 per cent of the men and 79 per cent of the women were re-examined; 7 per cent of the men and 4 per cent of the women had died and the remainder were not re-examined fo...

journal_title：Age and ageing

authors： Milne JS,Chopin JM

更新日期：1975-08-01 00:00:00

abstract：Background:there is growing consensus around the importance of population level approaches which seek to improve public knowledge and awareness of dementia. Aim:to assess knowledge of the relationship between dementia and ageing, and of the risk and protective factors associated with it, among the general public in Ir...

journal_title：Age and ageing

authors： Glynn RW,Shelley E,Lawlor BA

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Some patients may have medication-related risk factors only identified by home visits, but the extent to which those risk factors are associated with poor health outcomes remains unclear. OBJECTIVE:To determine the association between medication-related risk factors and poor patient health outcomes from obs...

journal_title：Age and ageing

authors： Sorensen L,Stokes JA,Purdie DM,Woodward M,Roberts MS

更新日期：2005-11-01 00:00:00

abstract：:Capillary fragility has been examined in 110 elderly patients, excluding those patients who might have been expected to have abnormal fragility. Nonetheless, fragility appeared to be greater in elderly patients than in younger subjects. It was much increased in the non-paralysed arm of hemiplegic patients but not in t...

journal_title：Age and ageing

authors： Bloomer J,Morley H,Denham MJ,Hodkinson HM

更新日期：1978-05-01 00:00:00

abstract：OBJECTIVE:to examine the association of physical activity and cardio-respiratory fitness with dehydroepiandrosterone sulphate (DHEAS), insulin-like growth factor I (IGF-I) and testosterone in healthy elderly people. DESIGN:cross-sectional study. SETTING:university research department and department of geriatric medic...

journal_title：Age and ageing

authors： Bonnefoy M,Kostka T,Patricot MC,Berthouze SE,Mathian B,Lacour JR

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVES:to compare walking speed in the UK older population with the speed required to utilise pedestrian crossings (≥1.2 m/s), and determine health and socio-demographic associations with walking impairment. DESIGN:cross-sectional study using Health Survey for England 2005 data. SETTING:private households in Engl...

journal_title：Age and ageing

authors： Asher L,Aresu M,Falaschetti E,Mindell J

更新日期：2012-09-01 00:00:00

abstract：:The objective of this study was to determine whether the Short-form 36 Health Status Questionnaire (SF-36) is suitable for use in an elderly population. The SF-36 was administered by interview to a random sample of 827 adults from West Glamorgan. Among the 216 adults aged 65 and over the data were 98.8% complete. Evid...

journal_title：Age and ageing

authors： Lyons RA,Perry HM,Littlepage BN

更新日期：1994-05-01 00:00:00

abstract：:There have so far been no reported studies of localization of urinary tract infection (UTI) in elderly women. The site of infection, renal or bladder, in significant urinary tract infection in 50 elderly women (mean age 80) admitted acutely to a geriatric unit was determined by the Fairley bladder washout method. Of t...

journal_title：Age and ageing

authors： Suntharalingam M,Seth V,Moore-Smith B

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:dysphagia is common in acute stroke. Accurate detection of the presence or absence of aspiration by bedside swallowing assessment is difficult without objective methods, tending to over-diagnose aspiration. As a result, some patients suffer restricted oral intake unnecessarily. OBJECTIVE:we examined the pre...

journal_title：Age and ageing

authors： Smith HA,Lee SH,O'Neill PA,Connolly MJ

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:early mobilization after hip fracture (HF) is an important predictor of outcome, but knowledge of the consequences of not achieving the pre-fracture basic mobility status in acute hospital recovery is sparse. OBJECTIVE:we examined whether the regain of pre-fracture basic mobility status evaluated with the c...

journal_title：Age and ageing

authors： Kristensen MT,Öztürk B,Röck ND,Ingeman A,Palm H,Pedersen AB

更新日期：2019-03-01 00:00:00

abstract：:Alcohol consumption constitutes a substantial burden of disease. Older people are being admitted to hospital for alcohol problems in increasing numbers. A recent systematic review reports cautious supportive evidence for primary prevention interventions in reducing excessive alcohol consumption in older drinkers, but ...

journal_title：Age and ageing

authors： Crome IB,Crome P

更新日期：2018-03-01 00:00:00

abstract：:Two studies of the social behaviour of geriatric patients are reported. In the first, lunchtime observations were made of two comparable wards in a continuing-care hospital and all episodes of social interaction recorded. There were twice as many interactions on one ward as on the other and their type and variety diff...

journal_title：Age and ageing

authors： Davies AD,Snaith PA

更新日期：1980-05-01 00:00:00

abstract：:There are few certainties in life-death is one of them. Yet death is often thought of today as the 'loss of the battle' against illness, where in traditional societies it was the natural, meaningful, end to life. Medical knowledge and technologies have extended the possibilities of medical care and increased our life ...

journal_title：Age and ageing

authors： Gellie A,Mills A,Levinson M,Stephenson G,Flynn E

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:fall-risk assessment with fall-prevention intervention referral for at-risk groups to avoid falls could be cost-effective from a care-payer perspective. AIMS:to model the cost-effectiveness of a fall-risk assessment (QTUG compared to TUG) with referral to one of four fall-prevention interventions (Otago, Fa...

journal_title：Age and ageing

authors： Franklin M,Hunter RM

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:to review systematically the range of case definitions and methods used to measure falls in randomised controlled trials. DESIGN/METHODS:a Cochrane review of fall prevention interventions was used to identify fall definitions in published trials. Secondary searches of various databases were used to identify ...

journal_title：Age and ageing

authors： Hauer K,Lamb SE,Jorstad EC,Todd C,Becker C,PROFANE-Group.

更新日期：2006-01-01 00:00:00

abstract：:Sporadic Creutzfeld-Jakob disease (CJD) is a rare neurodegenerative disorder. It is uniformly fatal. Clinical signs include myoclonus, visual disturbances, cerebellar ataxia, akinetic mutism and pyramidal/extrapyramidal signs in addition to a rapidly progressive dementia. Premortem diagnosis is challenging due to the ...

journal_title：Age and ageing

authors： Podger H,Ipe A

更新日期：2020-04-27 00:00:00

abstract：BACKGROUND:home visits and telephone calls are two often used approaches in transitional care, but their differential economic effects are unknown. OBJECTIVE:to examine the differential economic benefits of home visits with telephone calls and telephone calls only in transitional discharge support. DESIGN:cost-effect...

journal_title：Age and ageing

authors： Wong FK,So C,Chau J,Law AK,Tam SK,McGhee S

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:information about the predictors of mortality among the oldest-old is limited. Also possible gender differences are poorly known. OBJECTIVE:to examine the predictors of mortality among individuals aged 90 and older, focusing on differences between men and women. We also analysed gender differences in surviv...

journal_title：Age and ageing

authors： Tiainen K,Luukkaala T,Hervonen A,Jylhä M

更新日期：2013-07-01 00:00:00