Abstract:
:In two separate experiments, rats received either kainic acid (KA), 6-hydroxydopamine (6-OHDA) or control lesions bilaterally into either the anteromedial or ventrolateral neostriatum. Both ventrolateral neurotoxic lesions disrupted post-operative body weight regulation and the acquisition of a DRL-20 sec operant schedule of reinforcement. The pattern of operant responding suggested that these animals had an impairment in response sequencing or switching. Rats with anteromedial lesions manifested neither body-weight nor DRL impairments.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Dunnett SB,Iversen SDdoi
10.1016/0166-4328(82)90024-9subject
Has Abstractpub_date
1982-11-01 00:00:00pages
213-26issue
3eissn
0166-4328issn
1872-7549pii
0166-4328(82)90024-9journal_volume
6pub_type
杂志文章abstract::The objective of the present study was to evaluate whether maternal hyperleptinaemia programs anxiety-like and novelty-seeking behaviors as well as short-term memory/learning in adult male Wistar rats. During the first 10 days of lactation dams were s.c. injected with either murine leptin (LEP) or saline (CON). Adult ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2009.08.029
更新日期:2010-01-05 00:00:00
abstract::Chronic administration of cocaine can cause pronounced and enduring cognitive alterations such as increases in impulsive choice. Chronic cocaine can also result in enhanced dopamine (DA) release in the nucleus accumbens (NAc) in response to reward-related cues. It is possible that this enhanced DA release in the NAc i...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.01.001
更新日期:2017-03-15 00:00:00
abstract::Sociability is the prerequisite to social living. Oxytocin and the hypothalamo-pituitary-adrenocortical axis mediate various social behaviors across different social contexts in different rodents. We hypothesized that they also mediate levels of non-reproductive social behavior. Here we explored naturally occurring va...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.08.020
更新日期:2014-11-01 00:00:00
abstract::Biperiden is one of the most commonly abused anticholinergic drugs. This study assessed its motivational effects in the acquisition of conditioned place preference in rats. Biperiden neither produced place conditioning itself nor enhanced the rewarding effect of morphine. Furthermore, biperiden in combination with hal...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2011.07.050
更新日期:2011-12-01 00:00:00
abstract::Antagonists of group I metabotropic receptors exhibit anxiolytic action in adult rats. In immature animals we demonstrated anticonvulsant action of MPEP and AIDA, antagonists of group 5 and group 1, respectively. However, there are no developmental data on anxiolytic-like and learning actions of both compounds. This s...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2009.05.032
更新日期:2009-12-01 00:00:00
abstract::Previous research has shown that children living in clandestine methamphetamine (MA) labs are passively exposed to the drug [1]. The long-term effects of this early exposure on the dopaminergic systems are unknown, but may be important for adult behaviors mediated by dopamine, such as drug addiction. The current study...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2012.01.013
更新日期:2012-04-01 00:00:00
abstract::Rats depleted of dopamine by intraventricular or nigrostriatal bundle 6-hydroxydopamine injection were compared with normal rats on acquisition and retention of place and cue navigation in the Morris swimming pool test and on a battery of sensorimotor tests. Rats with extensive bilateral dopamine depletions were able ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(85)90165-2
更新日期:1985-10-01 00:00:00
abstract::Tactile stimulation has been reported to be effective as a treatment for inducing growth in premature human babies and infant rats and for improving functional recovery after brain injury in infant rats. We wondered if the behavioral impairments following injury in adulthood would show similar improvements with tactil...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2010.04.008
更新日期:2010-12-06 00:00:00
abstract::Among learning and memory processes, fear memories are crucial in some psychiatric disorders like post-traumatic stress disorder (PTSD). Accumulating evidence shows that the sigma-1 receptor (Sig-1R) has comprehensive involvement in cognitive impairment and neuroprotective effects. It has also been reported that BDNF ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2016.05.056
更新日期:2016-09-15 00:00:00
abstract::Mild neurocognitive impairments are common in people with human immunodeficiency virus (HIV) infection. HIV-encoded proteins, such as trans-activator of transcription (TAT), contribute to neuropathology and cognitive function in medicated subjects. The combination of TAT and comorbid methamphetamine use may further im...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2018.04.046
更新日期:2018-09-03 00:00:00
abstract::The study examined the relationship between risk-taking behavior during selection of monetary rewards and activations in the anterior cingulate cortex (ACC), orbitofrontal cortex (OFC) and medial prefrontal cortex (mPFC), brain regions that are associated with decision-making. Thirty-three adolescents with no personal...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2010.09.033
更新日期:2011-02-02 00:00:00
abstract::Previous DTI studies have reported associations between white matter integrity and performance on the Stroop interference task. The current study aimed to add to these studies of inhibitory control by investigating how the differences in age and in white matter integrity relate to Stroop performance, and to examine wh...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.11.005
更新日期:2018-02-26 00:00:00
abstract::The ventral part of the anteromedial thalamic nucleus (AMv) is heavily targeted by the dorsal premammillary nucleus (PMd), which is the main hypothalamic site that is responsive to both predator and conspecific aggressor threats. This PMd-AMv pathway is likely involved in modulating memory processing, and previous fin...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.10.038
更新日期:2018-02-26 00:00:00
abstract::Neurons in the isthmo-optic nucleus (ION) of the avian midbrain receive input predominantly from the ipsilateral optic tectum and project to the contralateral retina. Therefore, lesion in the ION removes tectal efferent signals to the retina in birds. In the present study, we trained Japanese quail to reach a target s...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2012.05.008
更新日期:2012-08-01 00:00:00
abstract::The MAM-E17 model is one of the most accepted schizophrenia rat models, which follows the neurodevelopmental theory of the disease. While symptoms of MAM-E17 rats were studied extensively, their examinations were usually restricted to adulthood and in a few cases to prepuberty. It is well known, however, that schizoph...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.05.065
更新日期:2017-08-14 00:00:00
abstract::Rats were trained to respond to the lever above which a light stimulus was briefly (0.5 s) presented at unpredictable times. Once the task had been learned to criterion, subjects were injected, intra-peritoneally, with arginine8-vasopressin, desglycinamide arginine8-vasopressin (AVP or DGAVP: 0, 5, 10 or 20 micrograms...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(88)90050-2
更新日期:1988-07-01 00:00:00
abstract::Serotonin plays a major role in sensory processing especially with in the primary auditory cortex. The so-called loudness dependence of auditory evoked potentials is generated by pyramidal cells of the primary auditory cortex (LDAEP) which are modulated by serotonergic projection fibers to the main regulators of pyram...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/j.bbr.2014.05.042
更新日期:2015-01-15 00:00:00
abstract::In the olfactory epithelium, olfactory sensitive neurons and their axons are surrounded by glia-like cells called sustentacular cells, which maintain both the structural and ionic integrity of the olfactory mucosa. We have previously found that endothelin-1 (ET-1) can uncouple sustentacular cell gap junctions in vitro...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2018.12.048
更新日期:2019-04-19 00:00:00
abstract::Pit vipers use infrared-sensitive pit organs to accurately target homeothermic prey even in the absence of visual cues. It has been suggested that other vipers, including large ambush predators of the genus Bitis, also may use radiant infrared information for predatory targeting. We compared behavioral responses of pi...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2004.01.020
更新日期:2004-09-23 00:00:00
abstract::Glutamatergic signaling plays an important role in learning and memory. Using Pavlovian conditioned approach procedures, the mechanisms that drive stimulus-reward learning and memory have been investigated. However, there are instances where reward-predictive stimuli can function beyond being solely predictive and can...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.10.013
更新日期:2018-02-15 00:00:00
abstract::At present neurobiological interests are directing more attention towards the major role of the amygdalar GABA(A) receptor on orexin-dependent behaviors. This telencephalic region has been widely studied especially in view of its control on various psychiatric disorders such as anxiety and depression. Recently, cross-...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2010.11.014
更新日期:2011-04-15 00:00:00
abstract:RATIONALE:Adolescent and adult rats show differential sensitivity to many of the effects of ethanol. OBJECTIVES:The current studies were designed to further explore differences in the development of ethanol dependence by examining anxiety-like behavior, acoustic startle, prepulse inhibition, and EEG activity during th...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2006.01.023
更新日期:2006-06-03 00:00:00
abstract::CGS 10746B is an imidazole-derivative related to the atypical antipsychotic clozapine which produces a decrease in dopamine release without altering dopamine metabolism or occupying D2 receptors. Rats were trained on an appetitively-motivated, two-choice, operant task to discriminate 20.0 mg/kg CGS 10746B from its veh...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(95)00167-0
更新日期:1996-01-01 00:00:00
abstract::Neural plasticity is a term that encompasses a vast array of changes in the nervous system in response to a wide range of environmental disturbances. The conservative manner in which nervous systems produce behavior is explored in the act of scratching the head. Whether the scratching is done with the hind leg (flamin...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2010.04.048
更新日期:2010-12-06 00:00:00
abstract::We used two procedures to assess the spatial learning and memory of rats in the Morris water maze task subsequent to kindling of hippocampal field CA1: (1) seizures were kindled with stimulation of CA1 prior to training in the water maze (acquisition); and (2) maze training was imposed until performance stabilized, se...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(97)81108-4
更新日期:1996-12-01 00:00:00
abstract::Taste memory depends on motivational and post-ingestional consequences after a single taste-illness pairing. During conditioned taste aversion (CTA), the taste and visceral pathways reach the nucleus of the solitary tract (NTS), which is the first relay in the CNS and has a vital function in receiving vagal chemical s...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.09.023
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Iron deficiency anemia (IDA) has been associated with altered cognitive, motor, and social-emotional outcomes in human infants. We recently reported that rats with chronic perinatal IDA, had altered regional brain iron, monoamines, and sensorimotor skill emergence during early development. OBJECTIVE:To exam...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2006.04.001
更新日期:2006-08-10 00:00:00
abstract::Rats learned to discriminate between two degrees of roughness, detecting the stimuli only with their vibrissal system. After bilateral trimming of the vibrissae, performance abruptly dropped to chance levels and remained there throughout the period in which the vibrissae were kept trimmed. After the vibrissae regrew t...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(89)90011-9
更新日期:1989-01-01 00:00:00
abstract::The study shows that although many features of copulation in decorticate male rats are normal, copulatory success is importantly dependent upon the control of approaches exerted by the normal female rat. Copulation by neonatally decorticated adult rats and normal adult rats was studied in cohabitation and videotaped t...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(85)90042-7
更新日期:1985-10-01 00:00:00
abstract::Bipolar disorder is a psychiatric condition characterised by episodes of mania, depression, and underlying mood instability. Anticonvulsant drugs have an established place in the treatment of the disorder, but identifying novel drugs in this class is complicated by the absence of validated animal models. We have evalu...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2004.08.015
更新日期:2005-03-07 00:00:00