[Granulomatous hepatitis successfully treated with ursodeoxycholic acid].

Abstract:

:The etiology of granulomatous hepatitis is extremely extensive for which the granulomatous reaction induced hepatic inflammation is characteristic. In the majority of cases it is part of a systemic disease but sometimes there is primer hepatic lesion in the background. The 21 year-old Caucasian female patient was taken to hospital having flu-like symptoms and icterus. While searching for the cause of her cholestatic hepatocellular lesion infections, tumors, storage diseases were excluded. However the root cause could not be identified. The histology showed granulomatous reaction, inflammation, intrahepatic bile duct proliferation and micronodular cirrhosis in the liver tissue. Taken it into consideration together with the the clinical picture and the laboratory findings primer sclerosing cholangitis was rendered probable. Her state deteriorated and even the necessity of liver transplantation emerged. The patient was treated with ursodeoxycholic acid which resulted in remission lasting for years now. Two years after the onset of the hepatic disease pancolitis ulcerosa with affection of the ileum terminalis was found in the patient which supports the diagnosis of primary sclerosing cholangitis.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Németh E,Bugovics E,Lengyel G,Pécsi G,Schaff Z,Fehér J

subject

Has Abstract

pub_date

2006-08-06 00:00:00

pages

1465-70

issue

31

eissn

0030-6002

issn

1788-6120

journal_volume

147

pub_type

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