Inflammatory melanoma.

abstract：:Twenty undifferentiated skin tumors were examined by immunostaining in an attempt to achieve more precise identification. Light microscopy yielded only a differential diagnosis, whereas immunostaining of formalin-fixed, paraffin-embedded tissue sections with a panel of antibodies to intermediate filaments and other ce...

journal_title：Journal of the American Academy of Dermatology

authors： Kahn H,Baumal R,From L

更新日期：1986-06-01 00:00:00

abstract：:In addition to the naturally occurring, physical, and systemic photoprotective agents reviewed in part I, topical ultraviolet radiation filters are an important cornerstone of photoprotection. Sunscreen development, efficacy, testing, and controversies are reviewed in part II of this continuing medical education artic...

journal_title：Journal of the American Academy of Dermatology

authors： Jansen R,Osterwalder U,Wang SQ,Burnett M,Lim HW

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Few studies have examined patients initially presenting with clinical features of urticarial dermatitis (UD). OBJECTIVE:We sought to examine clinical and laboratory evaluations and final diagnoses of patients with clinical features of UD. METHODS:This was a retrospective review of patients with UD seen at ...

journal_title：Journal of the American Academy of Dermatology

authors： Hannon GR,Wetter DA,Gibson LE

更新日期：2014-02-01 00:00:00

abstract：:Retinoids, synthetic vitamin A analogs, stimulate mucous metaplasia and gap-junction proliferation in embryonic and neoplastic epidermis. Such effects demonstrate that vitamin A has potent effects on epidermal differentiation. Oddly, however, retinoid action in normal postnatal tissues, where these drugs are used clin...

journal_title：Journal of the American Academy of Dermatology

authors： Elias PM

更新日期：1986-10-01 00:00:00

abstract：:It has previously been reported that interferon alfa injection sites may develop pyoderma gangrenosum, interface dermatitis, vasculitis, or, more commonly, ulcers characterized by intravascular thrombi and a mixed inflammatory cell infiltrate. We describe 2 patients in whom granulomatous and suppurative dermatitis dev...

journal_title：Journal of the American Academy of Dermatology

authors： Sanders S,Busam K,Tahan SR,Johnson RA,Sachs D

更新日期：2002-04-01 00:00:00

abstract：:Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trich...

journal_title：Journal of the American Academy of Dermatology

authors： Lober CW

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Some studies have shown that switching patients from one tumor necrosis factor (TNF)-alfa inhibitor to another may be beneficial when they have an inadequate response or an adverse event. OBJECTIVE:We sought to assess the variables predicting the efficacy of the second TNF-alfa inhibitor in patients discont...

journal_title：Journal of the American Academy of Dermatology

authors： Piaserico S,Cazzaniga S,Chimenti S,Giannetti A,Maccarone M,Picardo M,Peserico A,Naldi L,Psocare Study Group.

更新日期：2014-02-01 00:00:00

abstract：:Multiple basal cell epitheliomas developed in two psoriatic patients during treatment with orally administered 8-methoxypsoralen and long-wave ultraviolet radiation (PUVA). Twenty-two basal cell epitheliomas (BCEs) were seen in the two patients, 80% occurring in non-sun-exposed areas. Since neither patient had any his...

journal_title：Journal of the American Academy of Dermatology

authors： Brown FS,Burnett JW,Robinson HM Jr

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Patients with atopic dermatitis (AD) often have increased skin sensitivity and this symptom often worsens during stress. OBJECTIVE:We sought to find out whether patients with AD had stinging, and to identify the pathocausal neuroimmune mechanisms, including the role of stress. METHODS:In all, 25 patients w...

journal_title：Journal of the American Academy of Dermatology

authors： Lonne-Rahm S,Berg M,Mårin P,Nordlind K

更新日期：2004-12-01 00:00:00

abstract：:We report a case of a 10-month-old male infant with GM1 type 1 gangliosidosis who also had hyperpigmented macules and patches. Light and electron microscopic findings correlated with previously published reports on findings in skin biopsy specimens of patients with lipid storage disorders. The hyperpigmented macules a...

journal_title：Journal of the American Academy of Dermatology

authors： Selsor LC,Lesher JL Jr

更新日期：1989-05-01 00:00:00

abstract：:Cytodestructive or surgical therapy for patients with anogenital warts is frequently associated with recurrence. In February 1997, the US Food and Drug Administration approved imiquimod as a 5% cream for the treatment of anogenital warts. Activity of the drug results primarily from interferon alfa and other cytokine i...

journal_title：Journal of the American Academy of Dermatology

authors： Carrasco D,vander Straten M,Tyring SK

更新日期：2002-10-01 00:00:00

abstract：:We describe hereditary progressive mucinous histiocytosis, a rare autosomal dominant non-Langerhans cell histiocytosis, in a mother and daughter. Both had similar, progressive eruptions of skin-colored to red-brown papules on the nose, hands, forearms, and thighs. Light microscopy showed small collections of epithelio...

journal_title：Journal of the American Academy of Dermatology

authors： Schröder K,Hettmannsperger U,Schmuth M,Orfanos CE,Goerdt S

更新日期：1996-08-01 00:00:00

abstract：:Galli-Galli disease is an inherited disease characterized by slowly progressive and disfiguring reticulate hyperpigmentation of the flexures, clinically and histopathologically diagnostic for Dowling-Degos disease, but also associated with suprabasal, nondyskeratotic acantholysis. A few patients exhibiting these featu...

journal_title：Journal of the American Academy of Dermatology

authors： Braun-Falco M,Volgger W,Borelli S,Ring J,Disch R

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Genetic and environmental components may contribute to acne causation. OBJECTIVE:We sought to assess the impact of family history, personal habits, dietary factors, and menstrual history on a new diagnosis of moderate to severe acne. METHODS:We conducted a case-control study in dermatologic outpatient clin...

journal_title：Journal of the American Academy of Dermatology

authors： Di Landro A,Cazzaniga S,Parazzini F,Ingordo V,Cusano F,Atzori L,Cutrì FT,Musumeci ML,Zinetti C,Pezzarossa E,Bettoli V,Caproni M,Lo Scocco G,Bonci A,Bencini P,Naldi L,GISED Acne Study Group.

更新日期：2012-12-01 00:00:00

abstract：:As the most common human cancer worldwide and continuing to increase in incidence, basal cell carcinoma is associated with significant morbidity and cost. Continued advances in research have refined both our insight and approach to this seemingly ubiquitous disease. This 2-part continuing medical education article wil...

journal_title：Journal of the American Academy of Dermatology

authors： Cameron MC,Lee E,Hibler BP,Barker CA,Mori S,Cordova M,Nehal KS,Rossi AM

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Although cutaneous Crohn's disease is well recognized in adults, in children it is extremely rare. OBJECTIVE:Our purpose was to describe five children with cutaneous Crohn's disease and to review the literature. METHODS:The medical records of five children with cutaneous Crohn's disease were retrospectivel...

journal_title：Journal of the American Academy of Dermatology

authors： Ploysangam T,Heubi JE,Eisen D,Balistreri WF,Lucky AW

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Cutaneous basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) have poorer outcomes if treated when large. OBJECTIVE:We sought to estimate the growth rate of BCCs and SCCs and examine the relationship of personal, pathway, and cancer factors with cancer size (diameter). METHODS:We surveyed pati...

journal_title：Journal of the American Academy of Dermatology

authors： Kricker A,Armstrong B,Hansen V,Watson A,Singh-Khaira G,Lecathelinais C,Goumas C,Girgis A

更新日期：2014-03-01 00:00:00

abstract：:To develop guidelines for the follow-up of patients with primary cutaneous melanoma (clinical Stage I), we studied 295 patients who had presented with a primary melanoma and who subsequently developed evidence of metastatic disease in the course of follow-up. Cox multivariate analysis was used to assess the influence ...

journal_title：Journal of the American Academy of Dermatology

authors： Kelly JW,Blois MS,Sagebiel RW

更新日期：1985-11-01 00:00:00

abstract：:A tense yellow vesicle was noted on the back parietal scalp of a female newborn. This proved to be a bullous variant of aplasia cutis congenita. Only 16 cases of this apparently rare disorder have been previously reported. Histologic evaluation of such lesions reveals a distinct pattern containing fibrovascular stroma...

journal_title：Journal of the American Academy of Dermatology

authors： Colon-Fontanez F,Fallon Friedlander S,Newbury R,Eichenfield LF

更新日期：2003-05-01 00:00:00

abstract：:A newborn infant with subcutaneous fat necrosis and hypercalcemia is presented. Literature on the association between subcutaneous fat necrosis of the newborn and hypercalcemia is reviewed. Affected infants generally experience severe perinatal difficulties. Both vaginal deliveries and cesarean sections can be associa...

journal_title：Journal of the American Academy of Dermatology

authors： Norwood-Galloway A,Lebwohl M,Phelps RG,Raucher H

更新日期：1987-02-01 00:00:00

abstract：:Pyoderma gangrenosum is a rare and often painful skin disease that can be unpredictable in its response to treatment. There is currently no gold standard of treatment or published algorithm for choice of therapy. The majority of data comes from case studies that lack a standard protocol not only for treatment administ...

journal_title：Journal of the American Academy of Dermatology

authors： Miller J,Yentzer BA,Clark A,Jorizzo JL,Feldman SR

更新日期：2010-04-01 00:00:00

abstract：:Human papillomavirus infection is one of the most common and most distressing cutaneous diseases in patients with HIV infection. It is also a common, and often therapeutically challenging, infection in individuals who are immunologically competent. A wide range of therapeutic options exists for treating cutaneous huma...

journal_title：Journal of the American Academy of Dermatology

authors： Kottke MD,Parker SR

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Efalizumab inhibits multiple T-cell-mediated processes. OBJECTIVE:To evaluate 12- and 24-week efalizumab therapy for psoriasis. METHODS:In this phase III, randomized, double-blind trial, 498 patients received subcutaneous 1 or 2 mg/kg/wk efalizumab or placebo for 12 weeks. Efalizumab-treated patients who a...

journal_title：Journal of the American Academy of Dermatology

authors： Leonardi CL,Papp KA,Gordon KB,Menter A,Feldman SR,Caro I,Walicke PA,Compton PG,Gottlieb AB,Efalizumab Study Group.

更新日期：2005-03-01 00:00:00

abstract：:The hemophagocytic syndrome (HPS) was first described in immune-compromised patients with secondary viral infections. Immunodeficiency has not always been diagnosed before the onset of HPS, but most patients who develop HPS have known immune deficits. HPS has also been reported in association with lymphoreticular mali...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Skelton HG 3rd,Giblin WL,James WD

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:The mature psoriatic lesion does not necessarily demonstrate changes relevant to early phases of the lesion. OBJECTIVE:In a model for relapsing psoriasis we examined the epidermal phenotype by means of a panel of immunohistochemical parameters: keratins 14 and 16, epidermal growth factor receptor (EGFR), Ki...

journal_title：Journal of the American Academy of Dermatology

authors： Castelijns FA,Gerritsen MJ,van Vlijmen-Willems IM,van Erp PE,van de Kerkhof PC

更新日期：1999-06-01 00:00:00

abstract：:Benign lymphangiomatous papules of the skin are benign lymphatic proliferations that may arise in the skin after operation or radiation therapy. We report a case of benign lymphangiomatous papules of the skin that occurred in a patient 4 years after undergoing radiation therapy to the chest for adenocarcinoma of the b...

journal_title：Journal of the American Academy of Dermatology

authors： Wagamon K,Ranchoff RE,Rosenberg AS,Jaworsky C

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Vulvo-cervico-vaginal involvement has rarely been reported in pemphigus vulgaris (PV) and has not been reported in pemphigus foliaceus (PF). OBJECTIVES:We sought to evaluate genital lesions and Papanicolaou (Pap) smears in female patients with PV and PF. METHODS:This prospective study includes all consecut...

journal_title：Journal of the American Academy of Dermatology

authors： Fairbanks Barbosa ND,de Aguiar LM,Maruta CW,Aoki V,Sotto MN,Labinas GH,Perigo AM,Santi CG

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Associations between gluten intake and psoriasis, psoriatic arthritis, and atopic dermatitis are poorly understood. OBJECTIVE:To determine whether increased gluten intake is associated with incident psoriasis, psoriatic arthritis, and atopic dermatitis. METHODS:Cohort studies among women in Nurses' Health ...

journal_title：Journal of the American Academy of Dermatology

authors： Drucker AM,Qureshi AA,Thompson JM,Li T,Cho E

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:It is generally believed that dihydrotestosterone is one of the pivotal mediators of hair loss in androgenetic alopecia (AGA). Finasteride, which blocks the conversion of testosterone to dihydrotestosterone, has now become an integral part of the current treatment approaches for male AGA. Several lines of ev...

journal_title：Journal of the American Academy of Dermatology

authors： Tang L,Bernardo O,Bolduc C,Lui H,Madani S,Shapiro J

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Guselkumab, an interleukin-23 blocker, was superior to adalimumab in treating moderate to severe psoriasis in a phase II trial. OBJECTIVES:We sought to compare efficacy and safety of guselkumab with adalimumab and placebo in patients with psoriasis treated for 1 year. METHODS:Patients were randomized to gu...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Papp KA,Griffiths CE,Randazzo B,Wasfi Y,Shen YK,Li S,Kimball AB

更新日期：2017-03-01 00:00:00