Abstract:
:The supply of oxygen to tissue from capillaries may be influenced by hemorheological factors. A hemorheological model is developed for elucidating which factors play a major role in the oxygen transport to tissue. For a capillary tissue unit, a modified cylindrical model of Krogh is used. For blood, two fluids model of red blood cells (RBCs) and plasma is used where hemoglobin release effect is included. Non-equilibrium flows as well as equilibrium flows are examined for various parameters (total flow Q or RBC velocity Vr, discharge hematocrit Hd and capillary hematocrit Hc). In equilibrium flow, Hd and Q determine the oxygen transport. In non-equilibrium flow, Hc also becomes important. Especially, hemoglobin release effect becomes significant in low Hc flow, which affects the area of lethal region in tissue.
journal_name
Biorheologyjournal_title
Biorheologyauthors
Niimi H,Sugihara M,Yamakawa Tdoi
10.3233/bir-1983-20517subject
Has Abstractpub_date
1983-01-01 00:00:00pages
603-14issue
5eissn
0006-355Xissn
1878-5034journal_volume
20pub_type
杂志文章相关文献
BIORHEOLOGY文献大全abstract::Magnitude and time-dependence of the effects of red cell aggregation and sedimentation on the rheology of human blood were studied during low shear (tau W 2.5 to 92 mPa) flow through horizontal tubes (ID 25 to 105 microns). Immediately following reduction of perfusion pressure to a low value the red cell concentration...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1989-26210
更新日期:1989-01-01 00:00:00
abstract::We present data which show that fibrin gels are ordered network structures, the porosity of which is determined by the amount of thrombin being present during the activation step preceding gelation. On activation of fibrinogen, fibrinopeptides are released and simultaneously polymers are formed, obeying apparent first...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1984-211-214
更新日期:1984-01-01 00:00:00
abstract::This study investigated the changes in biorheological characteristics of skin after expansion. Expanders were implanted into the back of eight adult dogs, and after an eight-week expansion the expanded and the non-expanded control skins were transferred to an adjacent site. The expanded specimens and their controls we...
journal_title:Biorheology
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::The viscosity and the order in the interior of human erythrocyte membranes were investigated by the fluorescence depolarization technique in the nanosecond region with 1,6-diphenyl-1,3,5-hexatriene (DPH). After pulsed excitation with a polarized light, the fluorescence anisotropy ratio of DPH in membranes rapidly decr...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1986-23504
更新日期:1986-01-01 00:00:00
abstract::A rigidity index (RI) related to red blood cell deformability was measured by using the hemorheometre. The RI for 13 patients homozygous for sickle cell disease was 109 +/- 44 at 37 degrees C and at atmospheric pO2. The filtration time curve as a function of pO2 is biphasic for sickle cell suspensions. The pO2 at whic...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1989-26409
更新日期:1989-01-01 00:00:00
abstract::Since the sweet ketohexose L-sorbose causes overt hemolysis in dogs but not in man, we examined the possibility that L-sorbose induces a "prehemolytic state" of human red cells, manifesting itself as impairment of rheological red cell properties. After 2 hours incubation at 37 degrees C relative viscosity of red cell ...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1985-22302
更新日期:1985-01-01 00:00:00
abstract::The erythrocytes sedimentation profiles (ESP) of normal blood and of blood mixed with saline, albumin (7%), and various molecular weight dextrans of different concentrations, at various height and widths of the sample holder are determined. These observations show that the sedimentation characteristics of the erythroc...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1987-24106
更新日期:1987-01-01 00:00:00
abstract::It is widely accepted that whilst exhibiting clinically useful anti-inflammatory and analgesic activity, the application of non-steroidal anti-inflammatory drugs (NSAIDs) does not affect the underlying pathogenesis of articular diseases such as rheumatoid arthritis. The demonstration of a role for COX-2 in the resolut...
journal_title:Biorheology
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract::We have previously observed a stimulatory effect of fluid shear stress on the regeneration of cultured endothelial cell layers after mechanical denudation. In this study we examined how fluid shear stress affects endothelial cell DNA synthesis during regeneration. Following mechanical denudation of narrow linear areas...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1990-27505
更新日期:1990-01-01 00:00:00
abstract::The importance of biomechanical forces in regulating normal chondrocyte metabolism is well established and the mechanisms whereby mechanical forces are transduced into biochemical responses by chondrocytes are beginning to be understood. Previous studies have indicated that cyclical mechanical stimulation induces incr...
journal_title:Biorheology
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::Using a large scale model and the concept of dimensional similarity, we have developed a dimensionless correlation which permits the estimation of the drag force of blood flow in an in vivo vessel on a leukocyte adherent to the vessel wall. This relationship is [formula: see text] where Re is a Reynolds number, Cd is ...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.1016/0006-355X(96)00011-X
更新日期:1996-03-01 00:00:00
abstract::A number of risk factors including biomechanical stress on the articular cartilage imposed by joint overloading due to obesity, repetitive damage of the joint tissues by injury of the menisci and ligaments, and abnormal joint alignment play a significant role in the onset of osteoarthritis (OA). Genetic predisposition...
journal_title:Biorheology
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::The aim of this study was to investigate the effect of hydrostatic pressure on the expression of messenger ribonucleic acid (mRNA) for specific extracellular matrix proteins in chondrocytes. Chondrocytes obtained from bovine metatarsophalangeal joints were embedded in cylindrical 2% agarose gels. A novel experimental ...
journal_title:Biorheology
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::In the past few years there has been a considerable interest in the role of bone in osteoarthritis. Despite the increasing evidence of the involvement of bone in osteoarthritis, it remains very difficult to attribute the cause or effect of changes in subchondral bone to the process of osteoarthritis. Although osteoart...
journal_title:Biorheology
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::The membrane shear elastic modulus (mu) and the time constant for extensional shape recovery (tc) were measured for normal, control human red blood cells (RBC) and for RBC heat treated (HT) at 48 degrees C. Three separate methods for the measurement of mu were compared (two used a micropipette and one employed a flow ...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1985-22106
更新日期:1985-01-01 00:00:00
abstract::The application of principles of biorheology, hemorheology and perihemorheology on problems of the nervous system in health and disease was suggested by Alfred L. Copley (1982, 1987). Late in 1988 Copley and Sourander considered neurobiorheology to be an appropriate term for a new branch of biorheology bridging the ga...
journal_title:Biorheology
pub_type: 历史文章,杂志文章
doi:10.3233/bir-1991-28603
更新日期:1991-01-01 00:00:00
abstract::The Cell Transit Analyser (CTA) provides a means to rapidly measure the deformability of large numbers of individual cells. It combines many of the advantages of micropipette studies with the simplicity and speed of filtrometry methods by measuring the duration of each resistive pulse generated as a cell passes throug...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1992-292-301
更新日期:1992-03-01 00:00:00
abstract::Elevated shear stress levels in pathologically stenosed vessels induce platelet activation and aggregation, and may play a role in the pathogenesis of arterial disease. Increased plasma catecholamine concentrations have also been implicated in the onset of acute coronary ischemic syndromes. This study was designed to ...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.1016/0006-355X(96)00018-2
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:Postmenopausal women often develop hemorheological disorders which may affect the systemic blood circulation and present a cardiovascular risk factor. OBJECTIVE:We evaluated effects of secoisolariciresinol (SECO), a phytoestrogen, on hemorheological parameters and lipid peroxidation in a model of the age-re...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/BIR-15066
更新日期:2016-01-07 00:00:00
abstract:BACKGROUND:Osteoarthritis is a common, localized joint disease that causes pain, stiffness and reduced mobility. Osteoarthritis is particularly common in the knees. The effects of osteoarthritis on the rheology of synovial fluid in the knees are not fully understood and consequently require further study. OBJECTIVE:Th...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/BIR-15078
更新日期:2016-11-09 00:00:00
abstract:BACKGROUND:Leukocytes and platelets typically fulfil their functions through adhesion to the walls of vessels with different size, haematocrit and shear rate. OBJECTIVE:We aimed to investigate differential effects of these variables on leukocyte and platelet adhesion. METHODS:Blood with varying haematocrit was perfus...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/BIR-15043
更新日期:2015-01-01 00:00:00
abstract::Over the past several decades, blood-soluble drag reducing polymers (DRPs) have been shown to significantly enhance hemodynamics in various animal models when added to blood at nanomolar concentrations. In the present study, the effects of the DRPs on blood circulation were tested in anesthetized rats exposed to acute...
journal_title:Biorheology
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Pentoxifylline (PTX) has been reported to enhance the early accumulation of neutrophils at the site of Staphylococcus aureus subcutaneous infection in mice (1) and to stimulate in vitro PMN chemotaxis, particularly under dense agarose (2). Among the biochemical events contributing to chemotaxis are actin polymerizatio...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1990-273-421
更新日期:1990-01-01 00:00:00
abstract::Cervical mucus glycoproteins (mucins) were extracted by using slow stirring in 6M-guanidinium chloride supplemented with proteinase inhibitors. Subsequent purification was achieved by isopycnic density-gradient centrifugation in CsCl/guanidinium chloride. The whole mucins (Mr 10 X 10(6) - 15 X 10(6)) were degraded int...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1984-211-225
更新日期:1984-01-01 00:00:00
abstract::Stress relaxation regimes arising in a muscle subject to stepwise deformation are described on the basis of a recent phenomenological model of fully activated muscle tissue which is presented in the form of a second-order constitutive equation. It is shown that this model reproduces the qualitative form of relaxation ...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1984-21606
更新日期:1984-01-01 00:00:00
abstract::The presented paper is based on the conclusions of the preceding paper (1). On the basis of a general theoretical approach to the mechanics of heterogeneous materials published earlier / (2) , (3) , (4) / macroscopic constitutive equation of trabecular bone is deduced from the description of its microstructure. For th...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1983-20607
更新日期:1983-01-01 00:00:00
abstract::A non-biodegradable polyhedral oligomeric silsesquioxane (POSS) nanocomposite biopolymer has been developed for fabrication of medical devices and for tissue engineering human organs. The polymer in solution, containing 2 wt% of POSS, has been synthesized, characterized and investigated to determine its key rheologica...
journal_title:Biorheology
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Flow induced shear stress influences vascular cellular biology and pathophysiology in numerous ways. Previous in vitro studies on interactions between flow and endothelial cells using parallel-plate flow chambers involve two-dimensional flows, whereas flows in larger vessels are commonly three-dimensional. We have con...
journal_title:Biorheology
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::The structure of pulsatile flow in a rigid aortic bifurcation model was studied by means of a flow visualization technique and three-dimensional laser-Doppler anemometry. The model was made of glass, having the same shape as that of the average human aortic bifurcation. It was installed into a mock circulatory loop th...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/bir-1995-32104
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Blood flow in stenotic vessels strongly influences the progression of vascular diseases. Plaques in stenotic blood vessels vary in stiffness, which influences plaque behavior and deformation by pressure and flow. Concurrent changes in plaque geometry can, in turn, affect blood flow conditions. Thus, simultan...
journal_title:Biorheology
pub_type: 杂志文章
doi:10.3233/BIR-14016
更新日期:2015-01-01 00:00:00