Best-evidence interventions: findings from a systematic review of HIV behavioral interventions for US populations at high risk, 2000-2004.

Abstract:

OBJECTIVES:The Centers for Disease Control and Prevention's HIV/AIDS Prevention Research Synthesis Team conducted a systematic review of US-based HIV behavioral intervention research literature from 2000 through 2004 to identify interventions demonstrating best evidence of efficacy for reducing HIV risk. METHODS:Standard systematic review methods were used. Each eligible study was reviewed on the basis of Prevention Research Synthesis Team efficacy criteria that focused on 3 domains: study design, implementation and analysis, and strength of evidence. RESULTS:Eighteen interventions met the criteria for best evidence. Four targeted HIV-positive individuals. Of those targeting populations at risk for HIV, 4 targeted drug users, 6 targeted adults at risk because of heterosexual behaviors only, 2 targeted men who have sex with men, and 2 targeted youths at high risk. Eight interventions focused on women, and 13 had study samples with more than 50% minority participants. Significant intervention effects included increased condom use and reductions in unprotected sexual intercourse, number of sexual partners, injection drug use or needle sharing, and newly acquired sexually transmitted infections. CONCLUSIONS:Most of the best-evidence interventions are directly applicable for populations in greatest need of effective prevention programs; however, important gaps still exist.

journal_name

Am J Public Health

authors

Lyles CM,Kay LS,Crepaz N,Herbst JH,Passin WF,Kim AS,Rama SM,Thadiparthi S,DeLuca JB,Mullins MM,HIV\/AIDS Prevention Research Synthesis Team.

doi

10.2105/AJPH.2005.076182

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

133-43

issue

1

eissn

0090-0036

issn

1541-0048

pii

AJPH.2005.076182

journal_volume

97

pub_type

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