Effect of differentiation agents on expression of CA 125, alkaline phosphatase, and cytokeratins in human ovarian adenocarcinoma cells (OVCA 433).

abstract：OBJECTIVE:The purpose of this article is to review the data, rationale, and recommendations of vaginal brachytherapy (VBT) in the post-operative treatment of endometrial cancer patients. METHODS:The authors performed a thorough review of the medical literature regarding the use of adjuvant VBT in the treatment of endo...

journal_title：Gynecologic oncology

authors： Harkenrider MM,Block AM,Siddiqui ZA,Small W Jr

更新日期：2015-02-01 00:00:00

abstract：:The steroid receptor content of the primary endometrial cancer of 22 patients who were treated for recurrent or advanced disease has been measured and correlated with response to medroxyprogesterone acetate. No patient with a progesterone receptor (PR)-negative tumor responded and only 2 patients with PR-positive tumo...

journal_title：Gynecologic oncology

authors： Quinn MA,Cauchi M,Fortune D

更新日期：1985-07-01 00:00:00

abstract：:The relationship between fertility drug use and risk of borderline ovarian cancer has been analyzed using data from a case-control study. Cases were 93 women aged 23 to 64 years with histologically confirmed diagnosis of borderline ovarian tumor (according to the World Health Organization criteria) who were admitted t...

journal_title：Gynecologic oncology

authors： Parazzini F,Negri E,La Vecchia C,Moroni S,Polatti A,Chiaffarino F,Surace M,Ricci E

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Rectal tumors are rarely metastatic. Moreover, hematogenous spread is rare in ovarian cancer whose dissemination frequently occurs through peritoneal or lymphatic ways. CASE:A 55-year-old female presented with a rectal metastasis that appeared 20 years after the treatment of a primary clear cell carcinoma o...

journal_title：Gynecologic oncology

authors： Trastour C,Rahili A,Schumacker C,Effi AB,Bernard JL

更新日期：2004-08-01 00:00:00

abstract：:Ovarian germ cell tumors (GCTs) are rare in adults, but are more common in adolescents and young adults. Contemporary management of ovarian GCTs is evolving as collaboration among pediatric, medical, and gynecologic oncologists increases, and studies increasingly incorporate female adult patients. Despite an improved ...

journal_title：Gynecologic oncology

authors： Veneris JT,Mahajan P,Frazier AL

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:There is controversy regarding the pattern of lymphatic spread in unilateral stage I invasive ovarian carcinomas. The purpose of this study is to describe the incidence and distribution of lymph node (LN) metastases in ovarian carcinomas clinically confined to one ovary. METHODS:Ninety-six patients with diseas...

journal_title：Gynecologic oncology

authors： Cass I,Li AJ,Runowicz CD,Fields AL,Goldberg GL,Leuchter RS,Lagasse LD,Karlan BY

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:The expression of homologous recombination (HR) genes in high grade ovarian cancer (HGOC) samples from debulking surgeries were correlated to outcomes in patients selected for chemotherapy treatment regimens. STUDY DESIGN:RNA was extracted from 96 fresh frozen tumor samples from debulking surgeries from chem...

journal_title：Gynecologic oncology

authors： Kessous R,Octeau D,Klein K,Tonin PN,Greenwood CMT,Pelmus M,Laskov I,Kogan L,Salvador S,Lau S,Yasmeen A,Gotlieb WH

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Racial genetic admixture (RGA), a measure to account for ancestral genetic background that correlates with individual's racial classification, could provide insights on causation of racial disparity in endometrial cancer (EC). Our objective is to evaluate the association of RGA with EC outcomes. METHODS:EC pat...

journal_title：Gynecologic oncology

authors： Rocconi RP,Lankes HA,Brady WE,Goodfellow PJ,Ramirez NC,Alvarez RD,Creasman W,Fernández JR

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the impact of surgical complexity on postoperative complications and mortality, according to patient's frailty (mFI) following surgery for ovarian cancer. METHODS:Patients undergoing cytoreductive surgery for ovarian cancer from 2008 to 2018 were identified from our databa...

journal_title：Gynecologic oncology

authors： Di Donato V,Di Pinto A,Giannini A,Caruso G,D'Oria O,Tomao F,Fischetti M,Perniola G,Palaia I,Muzii L,Benedetti Panici P

更新日期：2020-09-04 00:00:00

abstract：:This study was designed to compare the effectiveness of loop excision procedures as ablation and conization equivalents, and their use in recurrent cervical high-grade dysplasia patients. We retrospectively reviewed patients undergoing loop procedures between January 1992 and April 1994. Conization equivalents were de...

journal_title：Gynecologic oncology

authors： Gold M,Dunton CJ,Murray J,Macones G,Hanau C,Carlson JA Jr

更新日期：1996-05-01 00:00:00

abstract：:Forty-two of sixty-seven patients (62.7%) treated for high-risk metastatic trophoblastic disease achieved and maintained complete remissions. The survival rate was significantly improved in those patients with scores lower than 8 according to a modification of the World Health Organization (WHO) prognostic scoring sys...

journal_title：Gynecologic oncology

authors： Gordon AN,Gershenson DM,Copeland LJ,Stringer CA,Morris M,Wharton JT

更新日期：1989-07-01 00:00:00

abstract：:Absorbable synthetic mesh (910-polyglactin) was used to create an intestinal sling in six patients undergoing surgical staging of pelvic malignancies prior to radiation therapy. All patients had effective compartmentalization of small intestine out of the pelvis which persisted throughout the duration of radiation the...

journal_title：Gynecologic oncology

authors： Soper JT,Clarke-Pearson DL,Creasman WT

更新日期：1988-03-01 00:00:00

abstract：:Pelvic washings for cytologic analysis have become an accepted diagnostic procedure in the management of endometrial carcinoma. A retrospective study was performed in 163 consecutive patients with FIGO Stage I and II endometrial carcinoma to assess the significance and value of the washings. Abnormal results were obta...

journal_title：Gynecologic oncology

authors： Kennedy AW,Peterson GL,Becker SN,Nunez C,Webster KD

更新日期：1987-09-01 00:00:00

abstract：:Taxol is one of the more significant advances in cancer chemotherapy in the last 10-15 years with a 30-50% response rate in both breast and ovarian cancers. The toxicity profile of taxol is still evolving as changes in the dosing and scheduling of the drug are instituted. We herein present the first evidence of taxol-...

journal_title：Gynecologic oncology

authors： Jerian SM,Sarosy GA,Link CJ Jr,Fingert HJ,Reed E,Kohn EC

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:To evaluate clinical outcome in patients selected to receive neoadjuvant chemotherapy (NACT) compared to primary debulking surgery (PDS). METHODS:Retrospective study including all consecutive patients diagnosed and treated for advanced (stages III-IV) ovarian cancers between the years 2003-2015. RESULTS:263...

journal_title：Gynecologic oncology

authors： Kessous R,Laskov I,Abitbol J,Bitharas J,Yasmeen A,Salvador S,Lau S,Gotlieb WH

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Practitioners and researchers require an outcome measure that accurately identifies the range of common treatment-induced changes in sexual function and well-being experienced by women after cervical or endometrial cancer. This systematic review critically appraised the measurement properties and clinical ut...

journal_title：Gynecologic oncology

authors： White ID,Sangha A,Lucas G,Wiseman T

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:One of the most active chemotherapy combinations in advanced or recurrent cervical cancer is cisplatin-paclitaxel. However, this palliative regimen is associated with significant toxicity. Carboplatin-paclitaxel is thus an attractive option. METHODS:Patients with advanced or recurrent carcinoma of the cervi...

journal_title：Gynecologic oncology

authors： Tinker AV,Bhagat K,Swenerton KD,Hoskins PJ

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:Ovarian cancer remains a leading cause of death in women and development of new therapies is essential. Second mitochondria derived activator of caspase (Smac) has been described to sensitize for apoptosis. We have explored the proapoptotic activity of a small molecule mimic of Smac/DIABLO on ovarian cancer ...

journal_title：Gynecologic oncology

authors： Petrucci E,Pasquini L,Petronelli A,Saulle E,Mariani G,Riccioni R,Biffoni M,Ferretti G,Benedetti-Panici P,Cognetti F,Scambia G,Humphreys R,Peschle C,Testa U

更新日期：2007-05-01 00:00:00

abstract：:In epithelial ovarian cancer, solitary metastasis to and recurrences in the parenchyma of the spleen are rare in the absence of apparent disease in other sites. We report four patients who developed isolated, solitary splenic parenchymal recurrences of their epithelial ovarian adenocarcinomas and underwent a splenecto...

journal_title：Gynecologic oncology

authors： Farias-Eisner R,Braly P,Berek JS

更新日期：1993-03-01 00:00:00

abstract：:Gynecologic oncology patients are at a high-risk of postoperative venous thromboembolism and these events are a source of major morbidity and mortality. Given the availability of prophylaxis regimens, a structured comprehensive plan for prophylaxis is necessary to care for this population. There are many prophylaxis s...

journal_title：Gynecologic oncology

authors： Barber EL,Clarke-Pearson DL

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:Members of the glutathione S-transferase (GST) family have been shown to have functional polymorphisms that may affect drug metabolism and influence the effects of chemotherapy and survival from cancer. GSTM1, GSTT1, and GSTP1 genotypes were evaluated for their role in ovarian cancer treatment and survival. ...

journal_title：Gynecologic oncology

authors： Beeghly A,Katsaros D,Chen H,Fracchioli S,Zhang Y,Massobrio M,Risch H,Jones B,Yu H

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and toxicity of interferon-alpha-2b (IFN-alpha) and cisplatin given concomitantly with radiation therapy (RT) in the treatment of locally advanced cervical carcinoma. MATERIALS AND METHODS:Twenty-one patients with stage bulky Ib-IIIb (Ib, 2; IIa, 2; IIb, 8; IIIb, 9) cervical carcinoma ...

journal_title：Gynecologic oncology

authors： Stock RG,Dottino P,Jennings TS,Terk M,DeWyngaert JK,Beddoe AM,Cohen C

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Recent scientific advances have lead to the development of a prophylactic, quadrivalent HPV vaccine conferring. We surveyed Latino and non-Latino women directly to examine what motivates them to vaccinate themselves, their daughters, and their sons. METHODS:A written survey was administered to 86 Latinas and...

journal_title：Gynecologic oncology

authors： Watts LA,Joseph N,Wallace M,Rauh-Hain JA,Muzikansky A,Growdon WB,del Carmen MG

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To determine the overall survival and relative effect of multiple prognostic variables in cohorts of patients with advanced-stage ovarian cancer treated with platinum-based neoadjuvant chemotherapy in lieu of primary cytoreductive surgery. METHODS:Twenty-two cohorts of patients with Stage III and IV ovarian ...

journal_title：Gynecologic oncology

authors： Bristow RE,Chi DS

更新日期：2006-12-01 00:00:00

abstract：:Flow cytometric DNA ploidy and S-phase fraction (SPF) analysis was performed on 18 granulosa cell tumors of the ovary. Clinical and pathologic data from patients followed for an average of 10 years were compared to flow cytometry ploidy to determine its prognostic usefulness. Eleven (62%) tumors were diploid and seven...

journal_title：Gynecologic oncology

authors： Roush GR,el-Naggar AK,Abdul-Karim FW

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVE:To define a prognostic score based on pretreatment values of leucocyte, platelet and hemoglobin in locally advanced cervical cancer (LACC). MATERIAL AND METHODS:We conducted a prospective study of 238 patients for LACC with negative PET imaging in the para-aortic (PA) area and who were undergoing laparoscopi...

journal_title：Gynecologic oncology

authors： Maulard A,Chargari C,Faron M,Alwohaibi A,Leary A,Pautier P,Genestie C,Morice P,Gouy S

更新日期：2020-11-01 00:00:00

abstract：:The cell line HTOA was established from a well-differentiated human ovarian serous cystadenocarcinoma. This line grew well and without interruption for 51 months and was subcultivated over 130 times. The cells were epithelial in shape, and neoplastic and pleomorphic features, a jigsaw puzzle-like arrangement, desmosom...

journal_title：Gynecologic oncology

authors： Ishiwata I,Ishiwata C,Soma M,Nozawa S,Ishikawa H

更新日期：1987-03-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) of the vulva is a rare, low- to intermediate-grade sarcoma of dermal origin. This case report represents the 13th reported patient with vulvar DFSP and the first reported patient with metastatic vulvar DFSP. Although metastasis is rare, the possibility remains that the frequent r...

journal_title：Gynecologic oncology

authors： Soergel TM,Doering DL,O'connor D

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:Ras gene mutations have been identified in squamous cell carcinomas of the cervix and are associated with advanced-stage tumors. The current study was designed to determine the prevalence of c-Ki-ras mutations in invasive endocervical adenocarcinomas and associations between mutations, HPV status, and known p...

journal_title：Gynecologic oncology

authors： Koulos JP,Wright TC,Mitchell MF,Silva E,Atkinson EN,Richart RM

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:The incidence of anemia in the cervical cancer patients treated with concurrent chemoradiotherapy is estimated to be more than 50%. Transfusion has been the mainstay of hematologic support with its inherent hazards including infection and transfusion reaction. The aim of this study was to examine the impact o...

journal_title：Gynecologic oncology

authors： Kim YT,Kim SW,Yoon BS,Cho HJ,Nahm EJ,Kim SH,Kim JH,Kim JW

更新日期：2007-04-01 00:00:00