Circadian rhythm of blood glucose values in critically ill patients.

abstract：OBJECTIVE:To discuss a possible role of the endothelium in sepsis. DATA SOURCES:Studies published in biomedical journals and our own experimental results. STUDY SELECTION:Studies on endothelial mechanisms in the context of sepsis. DATA EXTRACTION AND SYNTHESIS:Changes in endothelial cells on activation by inflammato...

journal_title：Critical care medicine

authors： Hack CE,Zeerleder S

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:Failure to detect clinical deterioration in the hospital is common and associated with poor patient outcomes and increased healthcare costs. Our objective was to evaluate the feasibility and accuracy of real-time risk stratification using the electronic Cardiac Arrest Risk Triage score, an electronic health r...

journal_title：Critical care medicine

authors： Kang MA,Churpek MM,Zadravecz FJ,Adhikari R,Twu NM,Edelson DP

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:Increases in exhaled nitric oxide have been demonstrated to originate from the lungs of rats after septic lung injury. The aim of this study was to investigate whether treatment with the nitric oxide synthase inhibitor N-nitro-L-arginine methyl ester (L-NAME) would prevent lipopolysaccharide (LPS)-induced in...

journal_title：Critical care medicine

authors： Aaron SD,Valenza F,Volgyesi G,Mullen JB,Slutsky AS,Stewart TE

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVES:Extracellular mitochondrial DNA and N-formyl peptides released following tissue damage may contribute to systemic inflammation through stimulation of the innate immune system. In this review, we evaluate existing in vivo human data regarding a role for mitochondrial DNA and N-formyl peptides in producing sys...

journal_title：Critical care medicine

authors： Lubkin DT,Bishawi M,Barbas AS,Brennan TV,Kirk AD

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Chronic diabetes mellitus (DM) is a known cause of multisystem injury. The effect of DM in acute critical illness may also be detrimental, but is not specifically known. We hypothesized that the preexisting diagnosis of DM is an independent risk factor for mortality in critically ill patients. DESIGN:Paralle...

journal_title：Critical care medicine

authors： Graham BB,Keniston A,Gajic O,Trillo Alvarez CA,Medvedev S,Douglas IS

更新日期：2010-01-01 00:00:00

abstract：:Right ventricular size and contractility were evaluated using two-dimensional echocardiography during the first days of respiratory support in 23 patients requiring mechanical ventilation for acute respiratory failure. Nine patients had normal echocardiographic right ventricular function, and nine other patients had a...

journal_title：Critical care medicine

authors： Jardin F,Gueret P,Dubourg O,Farcot JC,Margairaz A,Bourdarias JP

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVES:Acinetobacter baumannii complex bacteremia has been identified increasingly in critical patients admitted in ICUs. Notably, A. baumannii complex bacteremia has a high mortality rate, yet the risk factors associated with mortality remain unclear and controversial. DESIGN:Retrospective study. SETTING:All adu...

journal_title：Critical care medicine

authors： Lee HY,Chen CL,Wu SR,Huang CW,Chiu CH

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To study the natural evolution of systemic oxygen delivery (Do2) and oxygen consumption (Vo2) in sheep infused with low or high doses of endotoxin. DESIGN:Prospective, controlled experimental study. SETTING:Animal research laboratory at a medical university. SUBJECTS:Twenty-nine chronically instrumented aw...

journal_title：Critical care medicine

authors： Pittet JF,Pastor CM,Morel DR

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVES:To define the features of human amniotic mesenchymal stromal cell secretome and its protective properties in experimental models of acute brain injury. DESIGN:Prospective experimental study. SETTING:Laboratory research. SUBJECTS:C57Bl/6 mice. INTERVENTIONS:Mice subjected to sham or traumatic brain injury...

journal_title：Critical care medicine

authors： Pischiutta F,Brunelli L,Romele P,Silini A,Sammali E,Paracchini L,Marchini S,Talamini L,Bigini P,Boncoraglio GB,Pastorelli R,De Simoni MG,Parolini O,Zanier ER

更新日期：2016-11-01 00:00:00

abstract：:The definition of sepsis has been recently modified to accommodate emerging knowledge in the field, while at the same time being recognized as challenging, if not impossible, to define. Here, we seek to clarify the current understanding of sepsis as one that has been typically framed as a disorder of inflammation to o...

journal_title：Critical care medicine

authors： Alverdy JC,Krezalek MA

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To determine the impact of Acinetobacter baumannii (AB) acquisition in intensive care unit (ICU) patients on mortality and length of stay (LOS). DESIGN:Pairwise matched 1:1 case-control study. SETTING:Medical-surgical ICU in a tertiary health care institution. PATIENTS:During 16 months, all patients admitt...

journal_title：Critical care medicine

authors： García-Garmendia JL,Ortiz-Leyba C,Garnacho-Montero J,Jiménez-Jiménez FJ,Monterrubio-Villar J,Gili-Miner M

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:To explore the potential value of heart rate variability features for automated monitoring of sedation levels in mechanically ventilated ICU patients. DESIGN:Multicenter, pilot study. SETTING:Several ICUs at Massachusetts General Hospital, Boston, MA. PATIENTS:Electrocardiogram recordings from 40 mechanica...

journal_title：Critical care medicine

authors： Nagaraj SB,McClain LM,Zhou DW,Biswal S,Rosenthal ES,Purdon PL,Westover MB

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Evaluations of plasma leptin and ghrelin levels and their relations with circulating levels of proinflammatory mediators, stress hormones, and biochemical markers of hepatorenal injury during experimental endotoxemia in dogs. SETTING:Uludag University. DESIGN:Placebo-controlled animal study. ANIMALS:Adult ...

journal_title：Critical care medicine

authors： Yilmaz Z,Ilcol YO,Ulus IH

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:There has long-been controversy about the possible superiority of norepinephrine compared to dopamine in the treatment of shock. The objective was to evaluate the effects of norepinephrine and dopamine on outcome and adverse events in patients with septic shock. DATA SOURCES:A systematic search of the MEDLI...

journal_title：Critical care medicine

authors： De Backer D,Aldecoa C,Njimi H,Vincent JL

更新日期：2012-03-01 00:00:00

abstract：:To achieve synchronized differential pulmonary ventilation, an Ohio 560 ventilator was modified through separation of the outputs of the deep breath bellows and the tidal volume bellows and providing independent volume, flow rate, PEEP, oxygen-humidification, and alarm systems. The described ventilator modification is...

journal_title：Critical care medicine

authors： Popovich J Jr,Sanders OJ Jr,Vij D,Polanski JJ,Conway WA

更新日期：1981-06-01 00:00:00

abstract：OBJECTIVES:To determine how many multicenter, randomized controlled trials have been published that assess mortality as a primary outcome in the adult intensive care unit population, and to evaluate their methodologic quality. DATA SOURCE:A sensitive search strategy for randomized controlled trials was conducted in th...

journal_title：Critical care medicine

authors： Ospina-Tascón GA,Büchele GL,Vincent JL

更新日期：2008-04-01 00:00:00

abstract：:We describe the use of continuous negative extrathoracic pressure to treat successfully the adult respiratory distress syndrome in a 19-yr-old woman who resisted the application of positive airway pressure. Arterial hypoxemia was reversed with -26 cm H2O of extrathoracic pressure, produced by a modified Emerson iron l...

journal_title：Critical care medicine

authors： Morris AH,Elliott CG

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVES:Increasing time to mechanical ventilation and high-flow nasal cannula use may be associated with mortality in coronavirus disease 2019. We examined the impact of time to intubation and use of high-flow nasal cannula on clinical outcomes in patients with coronavirus disease 2019. DESIGN:Retrospective cohort ...

journal_title：Critical care medicine

authors： Hernandez-Romieu AC,Adelman MW,Hockstein MA,Robichaux CJ,Edwards JA,Fazio JC,Blum JM,Jabaley CS,Caridi-Scheible M,Martin GS,Murphy DJ,Auld SC,Emory COVID-19 Quality and Clinical Research Collaborative.

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To determine whether a correlation exists between concentrations of intracellular and extracellular potassium and to determine the frequency of ventricular ectopy in patients after cardiac operations. DESIGN:Prospective, observational clinical evaluation. SETTING:Surgical-respiratory intensive care unit of ...

journal_title：Critical care medicine

authors： Johnson RG,Shafique T,Sirois C,Weintraub RM,Comunale ME

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:Information booklets have not been assessed by the families of intensive care unit (ICU) patients. This study explored the information that the relatives of adult ICU patients wanted to find in the information booklets. DESIGN:Multicenter survey. SETTING:Twenty-three French ICUs. SUBJECTS:One close relativ...

journal_title：Critical care medicine

authors： Soltner C,Lassalle V,Galienne-Bouygues S,Pottecher J,Floccard B,Delapierre L,Jungfer F,Sargentini C,Alberti C,Beydon L,Lifrea Group.

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:The physicochemical approach, described by Stewart to investigate the acid-base balance, includes the strong ion gap (SIG), a quantitative measure of "unmeasured" anions, which strongly correlates to the corrected anion gap. The chemical nature of these anions is for the most part unknown. We hypothesized tha...

journal_title：Critical care medicine

authors： Moviat M,Terpstra AM,Ruitenbeek W,Kluijtmans LA,Pickkers P,van der Hoeven JG

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:The mortality outcome of mechanical ventilation, a key intervention in the critically ill, has been variously reported to be determined by intensive care patient volume. We determined the volume-(mortality)-outcome relationship of mechanically ventilated patients whose records were contributed to the Austral...

journal_title：Critical care medicine

authors： Moran JL,Solomon PJ,ANZICS Centre for Outcome and Resource Evaluation of the Australian and New Zealand Intensive Care Society.

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:To investigate the frequency, types, and implications of complications during intensive care in patients after status epilepticus has been successfully terminated. DESIGN:Retrospective study. SETTING:ICUs at a Swiss tertiary academic medical care center. PATIENTS:Data were collected from the digital patie...

journal_title：Critical care medicine

authors： Baumann SM,Semmlack S,De Marchis GM,Hunziker S,Rüegg S,Marsch S,Sutter R

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:To evaluate the methodological quality and thematic completeness of existing clinical practice guidelines, addressing early mobilization of adults in the ICU. DATA SOURCES:Systematic review of Medline, Embase, CINAHL, Cochrane, and grey literature from January 2008 to February 2020. STUDY SELECTION:Two rev...

journal_title：Critical care medicine

authors： Lang JK,Paykel MS,Haines KJ,Hodgson CL

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To review current knowledge about cell-free hemoglobin solutions. DATA SOURCES:All studies involving cell-free hemoglobin were retrieved from a computerized MEDLINE search from 1980 to 1998. We also reviewed the reference lists of all available review articles and primary studies to identify references not f...

journal_title：Critical care medicine

authors： Creteur J,Sibbald W,Vincent JL

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Delayed surfactant treatment (>2 hrs after birth) is less effective than early treatment in conventionally ventilated preterm infants with respiratory distress syndrome. The objective of this study was to evaluate if this time-dependent efficacy of surfactant treatment is also present during open lung ventila...

journal_title：Critical care medicine

authors： van Veenendaal MB,van Kaam AH,Haitsma JJ,Lutter R,Lachmann B

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:Most knowledge related to the pathophysiology of microcirculation in ischemic stroke comes from experimental research. Unfortunately, data on microcirculation in the human brain are limited, partially as a result of the lack of appropriate investigational techniques. The objective of our study was to test th...

journal_title：Critical care medicine

authors： Pérez-Bárcena J,Goedhart P,Ibáñez J,Brell M,García R,Llinás P,Jiménez C,Ince C

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential clinical, metabolic, and economic advantages of enteral nutrition over total parenteral nutrition. DESIGN:Prospective, randomized clinical trial. SETTING:Department of surgery in a university hospital. PATIENTS:Two hundred and fifty-seven patients with cancer of the stomach (n = 1...

journal_title：Critical care medicine

authors： Braga M,Gianotti L,Gentilini O,Parisi V,Salis C,Di Carlo V

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:Clinical trial designs that randomize patients to fixed treatment regimens may disrupt preexisting relationships between illness severity and level of therapy. The practice misalignments created by such designs may have unintended effects on trial results and safety. METHODS:To illustrate this problem, the T...

journal_title：Critical care medicine

authors： Deans KJ,Minneci PC,Suffredini AF,Danner RL,Hoffman WD,Ciu X,Klein HG,Schechter AN,Banks SM,Eichacker PQ,Natanson C

更新日期：2007-06-01 00:00:00

abstract：:To understand better the incidence and meaning of hyperamylasemia in the intensive care setting, cellulose acetate membrane electrophoresis was used to measure the isoenzymes of serum amylase in 192 patients with a variety of critical illnesses. Seventy of these patients had elevated serum amylase levels, but none had...

journal_title：Critical care medicine

authors： Weaver DW,Busuito MJ,Bouwman DL,Wilson RF

更新日期：1985-07-01 00:00:00