当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Exercise-induced ST depression and ST/heart rate index to predict triple-vessel or left main coronary disease: a multicenter analysis.

Exercise-induced ST depression and ST/heart rate index to predict triple-vessel or left main coronary disease: a multicenter analysis.

Abstract：

:The aim of this investigation was to determine the difference in accuracy between two frequently published noninvasive indicators of severity of coronary artery disease (exercise-induced ST segment depression and heart rate-adjusted ST depression [ST/HR index]). The study was designed as a survey of consecutive patients undergoing exercise electrocardiography and coronary angiography. There were a total of 2,270 patients without prior myocardial infarction or cardiac valvular disease referred for angiography from eight institutions in three countries; 401 of these patients had triple-vessel or left main coronary artery disease. The sensitivities of ST depression and ST/HR index in detecting triple-vessel or left main coronary artery disease were, respectively, 75% and 78% (p = 0.08) at cut point values where their specificities were equal (64%). This small increase in the accuracy of the ST/HR index was evident only at peak exercise heart rates below the median value of 132 beats/min, where the sensitivities of ST depression and ST/HR index were 73% and 76% (p = 0.03), respectively, at cut point values corresponding to a specificity of 60%. These results were consistent at all eight participating institutions. The increase in accuracy achieved by dividing exercise-induced ST depression by heart rate is small and confined exclusively to a low exercise heart rate. This lack of superiority cannot be generalized to all methods of heart rate adjustment.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Bobbio M,Detrano R,Schmid JJ,Janosi A,Righetti A,Pfisterer M,Steinbrunn W,Guppy KH,Abi-Mansour P,Deckers JW

doi

10.1016/0735-1097(92)90044-n

subject

Has Abstract,Author List Incomplete

pub_date

1992-01-01 00:00:00

pages

11-8

issue

1

eissn

0735-1097

issn

1558-3597

pii

0735-1097(92)90044-N

journal_volume

19

pub_type

临床试验,杂志文章,多中心研究

相关文献

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY文献大全
  • Ventricular arrhythmia induced by sodium channel blocker in patients with Brugada syndrome.

    abstract：OBJECTIVES:We administered pilsicainide chloride, a class Ic pure sodium channel blocker, to patients with Brugada syndrome (BS) and evaluated the occurrence of ventricular arrhythmia (VA) and T-wave alternans (TWA). BACKGROUND:Ventricular arrhythmia and TWA are sometimes induced by a sodium channel blocker challenge ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2003.06.004

    authors： Morita H,Morita ST,Nagase S,Banba K,Nishii N,Tani Y,Watanabe A,Nakamura K,Kusano KF,Emori T,Matsubara H,Hina K,Kita T,Ohe T

    更新日期：2003-11-05 00:00:00

  • Coronary angioplasty, atherectomy and bypass surgery in cardiac transplant recipients.

    abstract：OBJECTIVES:This study sought to analyze the outcomes of revascularization procedures in the treatment of allograft coronary disease. BACKGROUND:Allograft vasculopathy is the main factor limiting survival of heart transplant recipients. Because no medical therapy prevents allograft atherosclerosis, and retransplantatio...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/0735-1097(95)00124-i

    authors： Halle AA 3rd,DiSciascio G,Massin EK,Wilson RF,Johnson MR,Sullivan HJ,Bourge RC,Kleiman NS,Miller LW,Aversano TR

    更新日期：1995-07-01 00:00:00

  • Differential localization of atrial natriuretic peptide and skeletal alpha-actin messenger RNAs in left ventricular myocytes of patients with dilated cardiomyopathy.

    abstract：OBJECTIVES:This study was designed to determine whether atrial natriuretic peptide and skeletal alpha-actin messenger RNAs (mRNAs) are co-localized in ventricular myocytes of patients with dilated cardiomyopathy. BACKGROUND:Atrial natriuretic peptide and skeletal alpha-actin are known as augmented genes with cardiac h...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(95)00145-p

    authors： Tanaka M,Hiroe M,Ito H,Nishikawa T,Adachi S,Aonuma K,Marumo F

    更新日期：1995-07-01 00:00:00

  • Colchicine and antineoplastic therapy for the prevention of restenosis after percutaneous coronary interventions.

    abstract：:The complexity of the events that culminate in intimal proliferation after arterial injury and similarities between this response and benign neoplasia suggest that conventional medical therapies will continue to be unsuccessful in preventing recurrent stenosis after percutaneous coronary revascularization. By preventi...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/0735-1097(91)90948-9

    authors： Muller DW,Ellis SG,Topol EJ

    更新日期：1991-05-01 00:00:00

  • Pulmonary embolism after cardiac surgery.

    abstract：OBJECTIVES:We examined the incidence of pulmonary embolism after cardiac surgery. BACKGROUND:Because venous thromboembolism is considered to be an uncommon complication after cardiac surgery, its incidence was documented in a consecutive series of 1,033 patients who underwent cardiac surgery over a 5-year period. MET...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(93)90358-8

    authors： Josa M,Siouffi SY,Silverman AB,Barsamian EM,Khuri SF,Sharma GV

    更新日期：1993-03-15 00:00:00

  • Accelerated intimal thickening in carotid arteries of balloon-injured rats after immunization against heat shock protein 70.

    abstract：OBJECTIVES:The goal of this study was to test the hypothesis that induction of an immune response to heat shock protein (Hsp) 70 would increase intimal thickening in a rat carotid-injury model. BACKGROUND:Restenosis resulting from intimal thickening poses a major limitation to the long-term success of coronary angiopl...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(01)01579-0

    authors： George J,Greenberg S,Barshack I,Singh M,Pri-Chen S,Laniado S,Keren G

    更新日期：2001-11-01 00:00:00

  • Sex-related differences in clinical presentation and outcome of transcatheter aortic valve implantation for severe aortic stenosis.

    abstract：OBJECTIVES:The purpose of this study was to clarify the impact of sex-related differences in transcatheter aortic valve implantation (TAVI) for high-risk patients with severe aortic stenosis. BACKGROUND:Although TAVI is becoming a mature technique, the impact of sex differences remains unclear. METHODS:The TAVI patie...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2011.10.877

    authors： Hayashida K,Morice MC,Chevalier B,Hovasse T,Romano M,Garot P,Farge A,Donzeau-Gouge P,Bouvier E,Cormier B,Lefèvre T

    更新日期：2012-02-07 00:00:00

  • Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents.

    abstract：OBJECTIVES:This study sought to determine the incidence of aspirin nonresponsiveness in addition to clopidogrel nonresponsiveness and whether this association identifies patients at an increased risk of drug-eluting stent (DES) thrombosis. BACKGROUND:Nonresponsiveness to clopidogrel is a predictor of DES thrombosis. N...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jacc.2008.05.032

    authors： Gori AM,Marcucci R,Migliorini A,Valenti R,Moschi G,Paniccia R,Buonamici P,Gensini GF,Vergara R,Abbate R,Antoniucci D

    更新日期：2008-08-26 00:00:00

  • Advanced Management of Intermediate- and High-Risk Pulmonary Embolism: JACC Focus Seminar.

    abstract：:Intermediate-risk (submassive) pulmonary embolism (PE) describes normotensive patients with evidence of right ventricular compromise, whereas high-risk (massive) PE comprises those who have experienced hemodynamic decompensation with hypotension, cardiogenic shock, or cardiac arrest. Together, these 2 syndromes repres...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2020.05.028

    authors： Piazza G

    更新日期：2020-11-03 00:00:00

  • Prognostic value of dipyridamole stress cardiovascular magnetic resonance imaging in patients with known or suspected coronary artery disease.

    abstract：OBJECTIVES:We evaluated the prognostic value of dipyridamole stress cardiovascular magnetic resonance imaging (CMR) in patients with chest pain and known or suspected coronary artery disease. BACKGROUND:Stress perfusion CMR has been incorporated in daily practice. Data on its prognostic value are preliminary. METHODS...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2007.06.016

    authors： Bodi V,Sanchis J,Lopez-Lereu MP,Nunez J,Mainar L,Monmeneu JV,Husser O,Dominguez E,Chorro FJ,Llacer A

    更新日期：2007-09-18 00:00:00

  • Mechanisms of spontaneous shift of surface electrocardiographic configuration during ventricular tachycardia.

    abstract：OBJECTIVES:The aim of this study was to examine, with multichannel direct cardiac mapping techniques, the mechanisms of spontaneous shift of the QRS configuration in the surface electrocardiogram during episodes of ventricular tachycardia. BACKGROUND:Ventricular tachycardias demonstrating a spontaneous shift in their ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(92)90254-k

    authors： Kimber SK,Downar E,Harris L,Langer G,Mickleborough LL,Masse S,Sevaptsidis E,Chen TC

    更新日期：1992-11-15 00:00:00

  • Unexpected deviation in circadian variation of ventricular arrhythmias: the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial).

    abstract：OBJECTIVES:This study sought to determine whether circadian patterns in ventricular arrhythmias (VAs) occur in a current primary prevention defibrillator (implantable cardioverter-defibrillator [ICD]) population. BACKGROUND:Cardiovascular events, including VAs, demonstrate biorhythmic periodicity. METHODS:We tested f...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jacc.2013.11.072

    authors： Patton KK,Hellkamp AS,Lee KL,Mark DB,Johnson GW,Anderson J,Bardy GH,Poole JE,SCD-HeFT Investigators.

    更新日期：2014-06-24 00:00:00

  • Sodium Glucose Cotransporter-2 Inhibition and Cardiorenal Protection: JACC Review Topic of the Week.

    abstract：:Poorly controlled type 2 diabetes mellitus is associated with the development of cardiovascular and renal complications, resulting in significant morbidity and mortality. Intensive glycemic control has been a major focus for clinical trials and novel drug development. However, narrow treatment strategies developed str...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2019.09.022

    authors： Cherney DZ,Odutayo A,Aronson R,Ezekowitz J,Parker JD

    更新日期：2019-11-19 00:00:00

  • A comparison of mechanical and laser transmyocardial revascularization for induction of angiogenesis and arteriogenesis in chronically ischemic myocardium.

    abstract：OBJECTIVES:The purpose of the present study was to compare the use of a mechanical transmyocardial implant (TMI) device with transmyocardial laser revascularization (TMR) for induction of therapeutic angiogenesis and arteriogenesis in the chronically ischemic heart. BACKGROUND:Prior experimental studies have demonstra...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(02)01734-5

    authors： Hughes GC,Biswas SS,Yin B,Baklanov DV,Annex BH,Coleman RE,DeGrado TR,Landolfo CK,Landolfo KP,Lowe JE

    更新日期：2002-04-03 00:00:00

  • Acute occlusion in multiple lesion coronary angioplasty: frequency and management.

    abstract：:Among 3,548 patients undergoing a percutaneous transluminal coronary angioplasty procedure, 714 had multilesion angioplasty (1,550 lesions) in a single session. Acute occlusion occurred in 22 patients (3.1%) and 29 lesions (1.9%). The patients were classified into a group undergoing multivessel angioplasty (348 patien...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(89)90499-3

    authors： Gaul G,Hollman J,Simpfendorfer C,Franco I

    更新日期：1989-02-01 00:00:00

  • Nonpharmacological lipoprotein apheresis reduces arterial inflammation in familial hypercholesterolemia.

    abstract：BACKGROUND:Patients with familial hypercholesterolemia (FH) are characterized by elevated atherogenic lipoprotein particles, predominantly low-density lipoprotein cholesterol (LDL-C), which is associated with accelerated atherogenesis and increased cardiovascular risk. OBJECTIVES:This study used (18)F-fluorodeoxygluco...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2014.01.088

    authors： van Wijk DF,Sjouke B,Figueroa A,Emami H,van der Valk FM,MacNabb MH,Hemphill LC,Schulte DM,Koopman MG,Lobatto ME,Verberne HJ,Fayad ZA,Kastelein JJ,Mulder WJ,Hovingh GK,Tawakol A,Stroes ES

    更新日期：2014-10-07 00:00:00

  • Percutaneous balloon valvuloplasty in neonates with critical aortic stenosis.

    abstract：:Percutaneous balloon valvuloplasty was attempted in 10 newborn infants with critical aortic valve stenosis and severe congestive heart failure. Three had a very small left ventricle and aortic anulus. In one infant, the aortic valve could not be passed, and in another infant, a technical error resulted in severe valvu...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(89)90268-4

    authors： Kasten-Sportes CH,Piechaud JF,Sidi D,Kachaner J

    更新日期：1989-04-01 00:00:00

  • Effects of telmisartan added to Angiotensin-converting enzyme inhibitors on mortality and morbidity in hemodialysis patients with chronic heart failure a double-blind, placebo-controlled trial.

    abstract：OBJECTIVES:the aim of this study was to determine whether telmisartan decreases all-cause and cardiovascular mortality and morbidity in hemodialysis patients with chronic heart failure (CHF) and impaired left ventricular ejection fraction (LVEF) when added to standard therapies with angiotensin-converting enzyme inhibi...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2010.03.105

    authors： Cice G,Di Benedetto A,D'Isa S,D'Andrea A,Marcelli D,Gatti E,Calabrò R

    更新日期：2010-11-16 00:00:00

  • Paired comparisons of efficacy of intravenous and oral procainamide in patients with inducible sustained ventricular tachyarrhythmias.

    abstract：:Thirty-eight patients who had inducible sustained ventricular tachycardia during baseline programmed electrical stimulation underwent electrophysiologic testing after both intravenous and oral administration of procainamide. Each had presented clinically with documented sustained ventricular tachycardia or out of hosp...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(91)90651-o

    authors： Interian A Jr,Zaman L,Velez-Robinson E,Kozlovskis P,Castellanos A,Myerburg RJ

    更新日期：1991-06-01 00:00:00

  • High telomerase activity in neutrophils from unstable coronary plaques.

    abstract：OBJECTIVES:We evaluated telomerase activity in circulating polymorphonuclear neutrophils (PMN) and in PMN isolated from coronary atherosclerotic plaques by a novel approach. BACKGROUND:Delayed apoptosis of PMN have been demonstrated in unstable angina (UA). These cells have a finite lifespan with low telomerase activi...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2007.08.048

    authors： Narducci ML,Grasselli A,Biasucci LM,Farsetti A,Mulè A,Liuzzo G,La Torre G,Niccoli G,Mongiardo R,Pontecorvi A,Crea F

    更新日期：2007-12-18 00:00:00

  • Perspectives on dyslipidemia and coronary heart disease in women.

    abstract：:Coronary heart disease (CHD) remains the leading cause of death among American women. Numerous differences exist between younger and older women and between women and men with respect to the pathology of CHD and its incidence and prevalence over the life cycle. Differences in lipoprotein levels and lipid fractions pla...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2005.05.089

    authors： Bittner V

    更新日期：2005-11-01 00:00:00

  • Treatment of obstructive sleep apnea reduces the risk of atrial fibrillation recurrence after catheter ablation.

    abstract：OBJECTIVES:The aim of this study was to examine the effect of continuous positive airway pressure (CPAP) therapy on atrial fibrillation (AF) recurrence in patients with obstructive sleep apnea (OSA) undergoing pulmonary vein isolation (PVI). BACKGROUND:OSA is a predictor of AF recurrence following PVI. However, the im...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2013.03.052

    authors： Fein AS,Shvilkin A,Shah D,Haffajee CI,Das S,Kumar K,Kramer DB,Zimetbaum PJ,Buxton AE,Josephson ME,Anter E

    更新日期：2013-07-23 00:00:00

  • Impact of mechanical unloading on microvasculature and associated central remodeling features of the failing human heart.

    abstract：OBJECTIVES:This study investigates alterations in myocardial microvasculature, fibrosis, and hypertrophy before and after mechanical unloading of the failing human heart. BACKGROUND:Recent studies demonstrated the pathophysiologic importance and significant mechanistic links among microvasculature, fibrosis, and hyper...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2010.04.019

    authors： Drakos SG,Kfoury AG,Hammond EH,Reid BB,Revelo MP,Rasmusson BY,Whitehead KJ,Salama ME,Selzman CH,Stehlik J,Clayson SE,Bristow MR,Renlund DG,Li DY

    更新日期：2010-07-27 00:00:00

  • Transesophageal echocardiography and carotid ultrasound in patients with cerebral ischemia: prevalence of findings and recurrent stroke risk.

    abstract：OBJECTIVES:This study was conducted to determine the yield of transesophageal echocardiographic findings in a consecutive series of patients with stroke and transient ischemic attack, with and without carotid stenosis, and to estimate the recurrent stroke risk associated with specific echocardiographic findings. BACKG...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(94)90662-9

    authors： Comess KA,DeRook FA,Beach KW,Lytle NJ,Golby AJ,Albers GW

    更新日期：1994-06-01 00:00:00

  • Syncope in advanced heart failure: high risk of sudden death regardless of origin of syncope.

    abstract：OBJECTIVES:The purpose of this study was to assess the importance of syncope as a warning sign for sudden death in advanced heart failure and to determine the relative importance of cardiac syncope and syncope from other causes. BACKGROUND:Despite remarkable advances in the pharmacologic approach to advanced heart fai...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(93)90724-f

    authors： Middlekauff HR,Stevenson WG,Stevenson LW,Saxon LA

    更新日期：1993-01-01 00:00:00

  • The tyrosine phosphatase, SHP-1, is a negative regulator of endothelial superoxide formation.

    abstract：OBJECTIVES:We investigated the role of SH2-domain containing phosphatase-1 (SHP-1) in endothelial reduced nicotinamide adenine dinucleotide (phosphate) (NAD[P]H)-oxidase-dependent oxidant production. BACKGROUND:Superoxide (O2*-) generation by endothelial NAD(P)H-oxidase promotes endothelial dysfunction and atheroscler...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2005.02.039

    authors： Krötz F,Engelbrecht B,Buerkle MA,Bassermann F,Bridell H,Gloe T,Duyster J,Pohl U,Sohn HY

    更新日期：2005-05-17 00:00:00

  • Can nitrogen-13 ammonia kinetic modeling define myocardial viability independent of fluorine-18 fluorodeoxyglucose?

    abstract：OBJECTIVES:The hypothesis of this study was that evaluation of myocardial flow and metabolism using nitrogen-13 (N-13) ammonia kinetic modeling with dynamic positron emission tomographic (PET) imaging could identify regions of myocardial scar and viable myocardium as defined by fluorine-18 fluorodeoxyglucose (F-18 FDG)...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(96)00561-x

    authors： Beanlands RS,deKemp R,Scheffel A,Nahmias C,Garnett ES,Coates G,Johansen HL,Fallen E

    更新日期：1997-03-01 00:00:00

  • When children with Kawasaki disease grow up: Myocardial and vascular complications in adulthood.

    abstract：:Kawasaki disease (KD) is an acute, self-limited vasculitis that typically occurs in young children and was first described by Japanese pediatrician Tomisaku Kawasaki in 1967. Although originally thought to be a rare condition, KD has become the most common cause of acquired heart disease in the pediatric age group in ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2009.04.102

    authors： Gordon JB,Kahn AM,Burns JC

    更新日期：2009-11-17 00:00:00

  • Clinical correlates of PR-segment depression in asymptomatic patients with pericardial effusion.

    abstract：OBJECTIVES:The purpose of this study was to determine the clinical correlates of PR-segment depression among consecutive asymptomatic patients with pericardial effusion (PE) detected by routine echocardiography. BACKGROUND:Pericardial effusion is a relatively common finding in clinical practice, but not many studies h...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(02)01889-2

    authors： Kudo Y,Yamasaki F,Doi Y,Sugiura T

    更新日期：2002-06-19 00:00:00

  • Therapy with nitroglycerin increases coronary vasoconstriction in response to acetylcholine.

    abstract：OBJECTIVES:The purpose of this study was to investigate whether therapy with nitroglycerin (GTN) would lead to abnormal coronary artery responses to the endothelium-dependent vasodilator acetylcholine. BACKGROUND:Nitroglycerin therapy is associated with specific biochemical changes in the vasculature that may lead to ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0735-1097(98)00456-2

    authors： Caramori PR,Adelman AG,Azevedo ER,Newton GE,Parker AB,Parker JD

    更新日期：1998-12-01 00:00:00