Pyogenic osteomyelitis presenting as an acute sterile arthropathy.

abstract：:A nephelometric assay of concanavalin-A binding of serum acute phase proteins (con-A binding) has been used in cross-sectional and sequential studies of disease activity in rheumatoid arthritis (RA). Con-A binding correlated well with blood viscosity, C-reactive protein, and other individual acute phase reactants in p...

journal_title：Annals of the rheumatic diseases

authors： Martin MF,Dieppe PA,Jones HE,Warren C,Whicher J,Kohn J

更新日期：1982-04-01 00:00:00

abstract：:(1) An epidemiological study of a rural African community has been carried out in the Western Transvaal. Altogether 801 respondents over 15 years old were examined; radiographs of the hands and feet were obtained in all these individuals. Serological tests for rheumatoid factor were carried out on 516 blood samples. (...

journal_title：Annals of the rheumatic diseases

authors： Beighton P,Solomon L,Valkenburg HA

更新日期：1975-04-01 00:00:00

abstract：:The circulating levels of sialic acid (N-acetylneuraminic acid) and glycosaminoglycans (GAGs) were measured in 69 patients with spinal disorders of orthopaedic interest (ankylosing spondylitis 17, osteofluorosis 6, idiopathic backache 10, osteoarthrosis 16, osteoporosis 20). The serum GAG levels showed no statisticall...

journal_title：Annals of the rheumatic diseases

authors： Susheela AK,Das TK,Khurana JS,Jayaswal A,Dave PK

更新日期：1988-10-01 00:00:00

abstract：:The relationship between the tensile properties of articular cartilage and age has been investigated in vitro in the human knee joint. Specimens orientated parallel to the articular surface were excised from the superficial and deep zones of the femoral condyles of knee joints of persons in the age range from 8 to 91 ...

journal_title：Annals of the rheumatic diseases

authors： Kempson GE

更新日期：1982-10-01 00:00:00

abstract：OBJECTIVE:To compare median nerve conduction velocity measured using a new, portable electroneurometer with measurements made using conventional hospital nerve conduction apparatus. METHODS:Twenty five patients were studied who were consecutively referred to a hospital neurophysiology department with a clinical diagno...

journal_title：Annals of the rheumatic diseases

authors： Dunne CA,Thompson PW,Cole J,Dunning J,Martyn CN,Coggon D,Cooper C

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:To determine the clinical features associated with histologically proven rheumatoid vasculitis (HRV) and the additional diagnostic value of serological markers in an inception cohort of 81 patients with rheumatoid arthritis (RA) suspected of RV. METHODS:The presence and number of recently developed extra-art...

journal_title：Annals of the rheumatic diseases

authors： Voskuyl AE,Hazes JM,Zwinderman AH,Paleolog EM,van der Meer FJ,Daha MR,Breedveld FC

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVES:In salivary glands from patients with Sjögren syndrome, overexpression of laminins 1 and 5 and disorganisation of the acinar basal lamina have been reported. Laminin 5 mediates association of the basal lamina with epithelial cells by forming adhesion complexes upon interaction with alpha6beta4 integrin. In t...

journal_title：Annals of the rheumatic diseases

authors： Velozo J,Aguilera S,Alliende C,Ewert P,Molina C,Pérez P,Leyton L,Quest A,Brito M,González S,Leyton C,Hermoso M,Romo R,González MJ

更新日期：2009-06-01 00:00:00

abstract：:A previous infection of C3H mice with viable Mycoplasma pulmonis organisms protected them from arthritis induced by intravenous inoculation of these organisms, whether or not their initial arthritis had resolved at the time of challenge. Although spleen cells obtained from such animals conferred resistance to acute ar...

journal_title：Annals of the rheumatic diseases

authors： Taylor G,Taylor-Robinson D

更新日期：1977-06-01 00:00:00

abstract：OBJECTIVE:To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine (HCQ). METHODS:The case records of women (n = 33) exposed to HCQ during their pregnancies (n = 36) and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus ac...

journal_title：Annals of the rheumatic diseases

authors： Buchanan NM,Toubi E,Khamashta MA,Lima F,Kerslake S,Hughes GR

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVES:To perform a systematic literature review of effective strategies for the treatment of rheumatoid arthritis (RA). METHODS:As part of a European League Against Rheumatism (EULAR) Task Force investigation, a literature search was carried out from January 1962 until February 2009 in PubMed/Ovid Embase/Cochrane...

journal_title：Annals of the rheumatic diseases

authors： Knevel R,Schoels M,Huizinga TW,Aletaha D,Burmester GR,Combe B,Landewé RB,Smolen JS,Sokka T,van der Heijde DM

更新日期：2010-06-01 00:00:00

abstract：:Leishmaniasis is an intracellular protozoan infection that can lead to cutaneous, mucocutaneous, visceral or systemic manifestations depending on the parasite species and virulence and on the host immune response. It is endemic in countries of Europe (Mediterranean basin), Asia, Africa, Central and South America, but ...

journal_title：Annals of the rheumatic diseases

authors： Bogdan C

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Small studies have linked α1 antitrypsin (α1AT) deficiency to patients with antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV). OBJECTIVE:To test the validity and the mechanism of this association between α1AT and AAV. METHODS:The distribution of α1AT deficiency alleles Z and S was co...

journal_title：Annals of the rheumatic diseases

authors： Morris H,Morgan MD,Wood AM,Smith SW,Ekeowa UI,Herrmann K,Holle JU,Guillevin L,Lomas DA,Perez J,Pusey CD,Salama AD,Stockley R,Wieczorek S,McKnight AJ,Maxwell AP,Miranda E,Williams J,Savage CO,Harper L

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To identify predictors of radiographic progression in a 2-year randomised, double-blind, clinical study (CIMESTRA) of patients with early rheumatoid arthritis (RA). METHODS:Patients with early RA (n = 130) were treated with methotrexate, intra-articular betamethasone and ciclosporin/placebo-ciclosporin. Base...

journal_title：Annals of the rheumatic diseases

authors： Hetland ML,Ejbjerg B,Hørslev-Petersen K,Jacobsen S,Vestergaard A,Jurik AG,Stengaard-Pedersen K,Junker P,Lottenburger T,Hansen I,Andersen LS,Tarp U,Skjødt H,Pedersen JK,Majgaard O,Svendsen AJ,Ellingsen T,Lindegaard H,C

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To study further the temporal clustering of ankylosing enthesopathy (AE) noted originally during a study of the influence of mouse major histocompatibility complex (MHC) H-2 and transgenic HLA-B27 on the frequency of AE. METHODS:The relationship between maternal age at littering and frequency of AE was analy...

journal_title：Annals of the rheumatic diseases

authors： Weinreich S,Hoebe B,Ivanyi P

更新日期：1995-09-01 00:00:00

abstract：:Peripheral and axial bone mass and fracture incidence were studied in a group of 104 postmenopausal patients with rheumatoid arthritis (RA). Patients were divided into non-corticosteroid and low dose corticosteroid treated groups after elimination of patients with concomitant disease or therapy which might affect bone...

journal_title：Annals of the rheumatic diseases

authors： Verstraeten A,Dequeker J

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVE:To determine whether the amount of joint cartilage in healthy, middle aged men is stable or changes over time, and what factors may influence this. METHODS:In a cohort study, 28 healthy men (70% of the original cohort; mean (SD) age, 51.9 (12.8) years) had baseline knee magnetic resonance imaging (MRI) of th...

journal_title：Annals of the rheumatic diseases

authors： Hanna F,Ebeling PR,Wang Y,O'Sullivan R,Davis S,Wluka AE,Cicuttini FM

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:Notch signalling pathways are critical for angiogenesis and endothelial cell (EC) fate; however the mechanisms regulating these processes in the inflamed joint remain to be elucidated. Here, we examine whether Notch signalling mediates vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang2)-induce...

journal_title：Annals of the rheumatic diseases

authors： Gao W,Sweeney C,Walsh C,Rooney P,McCormick J,Veale DJ,Fearon U

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease (AID) worldwide. The disease is caused by mutations in the MEFV gene encoding the inflammasome sensor Pyrin. Clinical diagnosis of FMF is complicated by overlap in symptoms with other diseases, and interpre...

journal_title：Annals of the rheumatic diseases

authors： Van Gorp H,Huang L,Saavedra P,Vuylsteke M,Asaoka T,Prencipe G,Insalaco A,Ogunjimi B,Jeyaratnam J,Cataldo I,Jacques P,Vermaelen K,Dullaers M,Joos R,Sabato V,Stella A,Frenkel J,De Benedetti F,Dehoorne J,Haerynck F,C

更新日期：2020-07-01 00:00:00

abstract：AIM:to evaluate the effects of adalimumab, etanercept and infliximab on disease activity, functional ability and quality of life and the medication costs in a naturalistic design. METHODS:All patients from the Dutch Rheumatoid Arthritis Monitoring (DREAM) register starting on tumour necrosis factor (TNF)alpha-blocking...

journal_title：Annals of the rheumatic diseases

authors： Kievit W,Adang EM,Fransen J,Kuper HH,van de Laar MA,Jansen TL,De Gendt CM,De Rooij DJ,Brus HL,Van Oijen PC,Van Riel PC

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:An increased proportion of circulating follicular helper T (Tfh) cells was reported in rheumatoid arthritis (RA), but it remains uncertain how Tfh cells affect antibody hyposialylation. We investigated the regulation of autoantibody hyposialylation by Tfh cells in RA using murine model. METHODS:Behaviours of...

journal_title：Annals of the rheumatic diseases

authors： Kurata I,Matsumoto I,Ohyama A,Osada A,Ebe H,Kawaguchi H,Kaneko S,Kondo Y,Tsuboi H,Tomioka A,Kaji H,Sumida T

更新日期：2019-11-01 00:00:00

abstract：:The rapid introduction of immunotherapies for cancer-targeting immunological checkpoints has led to a new class of toxicities that appear to be of autoimmune and or autoinflammatory origin. These disorders are now referred to as immune-related adverse events (irAEs) and pose considerable challenges to patient care in ...

journal_title：Annals of the rheumatic diseases

authors： Calabrese L,Mariette X

更新日期：2018-02-01 00:00:00

abstract：:A novel explanation for the natural history of joint destruction in the early phase of ankylosing spondylitis is proposed on the basis of the clinical history, x-ray appearance, operative findings, and histopathology of a young patient believed to be suffering from the peripheral form of this disease. ...

journal_title：Annals of the rheumatic diseases

authors： Pasion EG,Goodfellow JW

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Increased apoptosis may induce autoimmune conditions. Apoptosis is induced by binding of death receptor ligands, members of the tumour necrosis factor (TNF) superfamily, to their cognate receptors. The Fas-Fas ligand pathway has been studied extensively in relation to systemic lupus erythematosus (SLE). Howe...

journal_title：Annals of the rheumatic diseases

authors： Lub-de Hooge MN,de Vries EG,de Jong S,Bijl M

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Spondyloarthritis is a group of articular disorders sharing a genetic background. Polymorphisms in the IL-1 gene cluster have previously been associated with ankylosing spondylitis (AS), a subset of spondyloarthritis. This study examined the association between several of these polymorphisms and the whole spo...

journal_title：Annals of the rheumatic diseases

authors： Monnet D,Kadi A,Izac B,Lebrun N,Letourneur F,Zinovieva E,Said-Nahal R,Chiocchia G,Breban M

更新日期：2012-06-01 00:00:00

abstract：:Using an in vitro system of cell migration from glass capillary tubes, the nonsteroidal, anti-inflammatory agents sodium salicylate, aspirin, ibuprofen, phenylbutazone, and indomethacin were shown to inhibit the migration of human peripheral leucocytes in a dose-related manner. This drug action was not confined to one...

journal_title：Annals of the rheumatic diseases

authors： Brown KA,Collins AJ

更新日期：1977-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine if neutrophils isolated from the blood and synovial fluid of patients with rheumatoid arthritis had patterns of receptor expression resembling those of blood neutrophils from controls which had been activated and primed in vitro. METHODS:Fluorescence activated cell sor...

journal_title：Annals of the rheumatic diseases

authors： Watson F,Robinson JJ,Phelan M,Bucknall RC,Edwards SW

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence and clinical associations of autoantibodies to myeloperoxidase (MPO) in an unselected series of well-characterised outpatients with rheumatoid arthritis (RA) and to compare the distribution of IgG subclasses of anti-MPO antibodies in these patients with that in patients with syste...

journal_title：Annals of the rheumatic diseases

authors： Cambridge G,Williams M,Leaker B,Corbett M,Smith CR

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To investigate the predictive value of discordance between (1) tender and swollen joint count and (2) patient's and evaluator's global assessment on remission in patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA). METHODS:From the prospective, multicentre Norwegian-Disease-Modifying Antirh...

journal_title：Annals of the rheumatic diseases

authors： Michelsen B,Kristianslund EK,Hammer HB,Fagerli KM,Lie E,Wierød A,Kalstad S,Rødevand E,Krøll F,Haugeberg G,Kvien TK

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:To test the hypothesis that PVAC, delipidated, deglycolipidated heat killed Mycobacterium vaccae, is an effective and safe treatment for psoriatic arthritis (PsA). This treatment has shown promising results in psoriasis. METHODS:36 patients with PsA in two centres were studied in this double blind, placebo ...

journal_title：Annals of the rheumatic diseases

authors： Dalbeth N,Yeoman S,Dockerty JL,Highton J,Robinson E,Tan PL,Herman D,McQueen FM

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Physical function in rheumatoid arthritis (RA) has reversible and irreversible components, and is typically assessed by the Health Assessment Questionnaire Disability Index (HAQ). Since irreversible components are expected to increase with longer duration of RA and reduce the ability for improvement in physi...

journal_title：Annals of the rheumatic diseases

authors： Aletaha D,Strand V,Smolen JS,Ward MM

更新日期：2008-02-01 00:00:00