[Long-term efficacy and safety of chondroitin sulphate (structum, France) in patients with coxarthrosis].

Abstract:

AIM:To evaluate long-term therapeutic effect and safety of structum in patients with manifest coxarthrosis. MATERIAL AND METHODS:Twenty patients with manifest coxarthrosis of degree I-III were given a 6 month structum course. Criteria of efficacy were Leken index, pain in the affected joints, nonsteroid anti-inflammatory drugs requirement, assessment of the efficacy by the patient and the doctor. Structum effects were studied with x-ray examination, CT, INC index. The assessment was made at baseline, after 3 and 6 month therapy and 6.12 and 18 months after the end of the study. RESULTS:All the patients achieved positive results without side effects on coagulation. CONCLUSION:Structum is highly effective in patients with manifest osteoarthrosis of hip joints. Is modifies symptoms, has a potential chondroprotective effect, long-term aftereffect, no significant negative action of coagulation, is well tolerated.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Shmidt EI,Bilinskaia MA,Belozerova IV,Soldatov DG,Dmitrieva ME

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

65-7

issue

1

eissn

0040-3660

issn

2309-5342

journal_volume

79

pub_type

杂志文章
  • [Hypertension and "silent" myocardial ischemia. I. The results of stress scintigraphy of the myocardium in patients].

    abstract::As many as 24 patients suffering from essential hypertension (EH) were examined. The patients were subjected to Holter ECG monitoring, echocardiography, coronary angiography, exercise scintigraphy of the myocardium with transesophageal pacing of the atria and the dipyridamole test. The patients manifested defects of t...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Dubov PB,Koniaeva EB,Ostroumov VB,Sergienko VB,Iurenev AP

    更新日期:1992-01-01 00:00:00

  • [Possibilities of active mass screening in the prevention of pulmonary hypertension in chronic bronchitis].

    abstract::The authors presented a comparative analysis of the time course of pulmonary blood pressure (PBP), cardiac output, total pulmonary resistance (TPR), and right ventricular capacity in 2 groups of patients with chronic obstructive bronchitis (COB) with moderately marked emphysema and pneumofibrosis at repeated examinati...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Volkova LI,Shteingardt IuN

    更新日期:1988-01-01 00:00:00

  • [Efferent therapy in the combined treatment of sepsis].

    abstract::Efferent therapy (hemosplenosorption, plasmapheresis, autologous blood radiation) was used in multimodality treatment of 45 patients with sepsis. The therapy exerted a beneficial effect on the disease, favoured the elimination of or minimized intoxication, normalized hemostasis and immunity. Indications for use of hem...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Neĭmark II,Ovchinnikov VA,Neĭmark MI,Rogachevskiĭ PA

    更新日期:1991-01-01 00:00:00

  • [The interdigestive phasic motility of the gallbladder and bile excretion in healthy subjects and in patients with duodenal peptic ulcer].

    abstract::Interdigestive phasic motility of the gallbladder and bile excretion into the duodenum were studied in 100 patients with duodenal ulcer (DU) and 20 healthy subjects. Gall bladder motility and bile excretion in both healthy and DU subjects directly depended on interdigestive phasic activity of the duodenum and gastric ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Reshetilov IuI,Orlovskiĭ VF,Surmylo NN,Kuznetsova LF,Protsenko NN,Klavdieva EIu,Perkina AA

    更新日期:1995-01-01 00:00:00

  • [Thyroid diseases in reproductive-age women living in Shoria mountains].

    abstract:AIM:To analyze prevalence and structure of thyroid pathology in women of reproductive age living in Shoria mountains. MATERIAL AND METHODS:The examination of 409 women aged 18 to 40 living in mountain Shoria included assessment of social status, heredity, actual nutrition, visit to endocrinologist, ultrasound investig...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kvitkova LV,Ushakova GA,Shchetinina EV,Ogarkov MIu,Cherniavskaia EIu,Polikutina OM,Kazachek IaV,Barbarash OL

    更新日期:2005-01-01 00:00:00

  • [The use of hemosorption and plasmapheresis for treating cardiac arrhythmias (a preliminary report)].

    abstract::The authors present pilot experience in extracorporeal blood purification (hemosorption, plasmapheresis) aimed at correction of cardiac arrhythmia. Seven responders of 8 patients treated had less frequent episodes of cardiac fibrillation the severity of which decreased, they suffered no more from high-grade extrasysto...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Nedostup AV,Panasiuk VV,Boldyrev DA,Kalugina GV,Ivanov MI,Komiagin IuV

    更新日期:1994-01-01 00:00:00

  • [Pharmacoepidemiological study of the course of influenza and other acute respiratory viral infections in risk groups].

    abstract:AIM:To identify risk factors (RFs) for the development of bacterial complications and the prolonged course of influenza and other acute respiratory viral infections (ARVIs) among inpatients treated in Russian healthcare facilities in the post-pandemic period; to determine the clinical presentation of the disease (flu-l...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh201789162-71

    authors: Bulgakova VA,Poromov AA,Grekova AI,Pshenichnaya NY,Selkova EP,Lvov NI,Leneva IA,Shestakova IV,Maleev VV

    更新日期:2017-01-01 00:00:00

  • [Interferon status of patients with non-specific ulcerous colitis and its correction with interferon inducers].

    abstract:AIM:To examine validity of using interferon inductors (amixin and cycloferon) in combined treatment of patients with non-specific ulcerous colitis (NUC). MATERIAL AND METHODS:113 NUC patients received basic antiinflammatory therapy (glucocorticoids and preparations of 5-aminosalycylic acid). Patients of groups 1 and 2...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:

    authors: Maev IV,Grigorian SS,Gadzhieva MG,Ovchinnikova NI,Ospel'nikova TP,Kaziulin AN

    更新日期:2002-01-01 00:00:00

  • [Physiological methods of treatment of patients with polycythemia vera].

    abstract::Based on an analysis of the data pertaining to changes in the level of erythropoietin, chalones and stress hormones in the blood of patients with polycythemia vera after bloodletings and cytapheresis it is concluded that chalones participate in the development of a remission owing to the inhibition of the clone of mut...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Neustroev GV

    更新日期:1985-01-01 00:00:00

  • [Immunologic phenotype of blast cells in the diagnosis of myeloblastic leukemias].

    abstract::A study was made of immunologic cell markers in 32 patients with acute myeloid leukemia by indirect immunofluorescence with the aid of xenogeneic antisera and monoclonal antibodies obtained by the authors. Ia-like antigen demonstrated by monoclonal antisera IKO-I expressed in myeloblastic leukemia with maturation in m...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Baryshnikov AIu,Volkova MA,Frenkel' MA,Tupitsyn NN,Morozova LF

    更新日期:1985-01-01 00:00:00

  • [Effect of bortezomib on the efficiency of hematopoietic stem cell mobilization in patients with multiple myeloma].

    abstract:AIM:To study the results of mobilizing and collecting autologous hematopoietic stem cells (HSC) in patients with multiple myeloma (MM) receiving bortezomib as part of induction therapy regimens. MATERIALS AND METHODS:In June 2001 to April 2010, the Department of Bone Marrow Transplantation, Hematology Research Center,...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Pokrovskaia OS,Mendeleeva LP,Urnova ES,Gaponova TV,Gal'tseva IV,Kuz'mina LA,Akhundova FM,Kalinin NN,Gretsov EM,Parovichnikova EN,Savchenko VG

    更新日期:2012-01-01 00:00:00

  • [Efficacy of one combined inhaled drug in the treatment of patients with bronchial asthma depending on the disease duration].

    abstract:AIM:To assess an effect of long-term administration of one combined inhaled drug containing glucocorticosteroids (GCS) and long-acting beta2-agonists (LABA) on patient compliance. MATERIAL AND METHODS:The trial included 47 patients (14 males and 33 females, mean age 48.8 +/- 13.2 years) with bronchial asthma (BA) of d...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ovcharenko SI,Akulova MN

    更新日期:2009-01-01 00:00:00

  • [Correlations between electrophysiological myocardial remodeling and parameters of free radical oxidation in patients with various forms of ischemic heart disease].

    abstract:AIM:To investigate potentialities of a novel biochemical test assessing oxidative resistance of plasma as a marker of ischemic damage to the myocardium and to study this marker correlation with high-performance ECG parameters reflecting electrophysiological remodeling of the myocardium in patients with ischemic heart d...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Drinitsina SV,Azizova OA,Piriazev AP,Korinevich AIu,Solov'eva NP,Ivanov GG,Lopukhin IuM

    更新日期:2006-01-01 00:00:00

  • [Dynamics of changes in levels of insulin, glucagon, and C-peptide during glucose tolerance test in patients with coronary atherosclerosis].

    abstract:AIM:To study velocity characteristics of changes in the levels of insulin, glucagon and C-peptide in the course of the intravenous glucose tolerance test (IGTT). MATERIAL AND METHODS:Glucose, insulin, glucagon and peptide levels were measured in the course of IGTT performed in 50 patients with coronary atherosclerosis...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Denisova TP,Malinov IA

    更新日期:2000-01-01 00:00:00

  • [Primary immunodeficiencies are a topical problem of modern medicine].

    abstract:AIM:To analyze the incidence of primary immunodeficiencies (PIDs), to reveal the specific features of the course of this condition at the present stage, and to estimate the quality of health care to patients with PIDs. SUBJECTS AND METHODS:An open-label prospective trial was performed in 94 patients with different for...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Troitskaya EV,Sofronova LV,Tsvetkova TY

    更新日期:2014-01-01 00:00:00

  • [Echodiagnosis of the kidney lesion in gout].

    abstract::An echographic study of the kidneys was performed in 24 men with proved gout aged 40 to 50 and a disease duration of 10-20 yrs. On the basis of case history data urolithiasis was noted in 4 patients, whereas by echodiagnosis it was found in 12. Cysts were detected in 6 patients with gout complicated by urolithiasis an...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Tsurko VV,Zeĭdlits LA,Akimova TF,Novoselova TM,Altunina AN

    更新日期:1986-01-01 00:00:00

  • [Possible pathogenetic mechanisms of spontaneous stenocardia attacks].

    abstract::Study of changes in the electrocardiogram during spontaneous attacks of angina pectoris has shown that out of 80 patients examined, 78 (98.6%) patients with angina pectoris at rest manifested ischemic-type changes in the end part of the ventricular complex of the ECG, whereas in 81% of the patients, rhythm and conduct...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ermilov LP,Kuleshova EV,Isakova TI

    更新日期:1985-01-01 00:00:00

  • The effectiveness of combination antihypertensive therapy in patients with arterial hypertension and additional risk factors: obesity and obstructive sleep apnea syndrome.

    abstract:AIM:To study the effectiveness of a fixed combination of perindopril and amlodipine, with the subsequent addition of indapamide-retard in male patients with arterial hypertension (AH), obesity and severe sleep apnea (OSAS). MATERIALS AND METHODS:The study included 43 male patients in whom antihypertensive therapy titr...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/00403660.2018.12.000005

    authors: Elfimova EM,Litvin AY,Chazova IE

    更新日期:2018-12-30 00:00:00

  • [Cystatin C is a new marker for left ventricular hypertrophy in patients with chronic kidney disease].

    abstract:AIM:To estimate the diagnostic value of serum cystatin C in the development of left ventricular hypertrophy (LVH) in patients with chronic kidney disease (CKD). SUBJECTS AND METHODS:The investigation enrolled 86 patients (53% men, 47% women; mean age, 45 ± 13 years) with nondiabetic CKD. According to the magnitude of ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh201587617-22

    authors: Vasilyeva MP,Rudenko TE,Kutyrina IM,Solomakhina NI

    更新日期:2015-01-01 00:00:00

  • [Assessment of awareness about the epidemiology, outcomes, and therapy of chronic hepatitis B and C in adolescents and adults].

    abstract:AIM:To estimate the level of knowledge in adults and adolescents about the issues related to viral hepatitis B and C: the transmission modes, course, and outcomes of acute and chronic hepatitis B (CHB) and C (CHC), as well as about current measures for their prevention and treatment. SUBJECTS AND METHODS:A total of 85...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh2016881137-42

    authors: Baramzina SV

    更新日期:2016-01-01 00:00:00

  • [Immunodiagnosis and immunotherapy of chronic nonspecific lung diseases].

    abstract::Altogether 212 patients with chronic nonspecific pulmonary diseases (CNPD) were examined. Of these, 105 patients received treatment with sodium nucleinate, 72 with levamisole, 17 with diucifon and 18 with T-activin. As compared with healthy subjects, the patients manifested significantly deviated immunological paramet...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Borisova AM

    更新日期:1985-01-01 00:00:00

  • [Economic assessment of efficacy of vasaprostan treatment of critical lower limbs ischemia].

    abstract:AIM:To estimate cost-effect efficacy of vasaprostan treatment of inpatients with arterial chronic obliteration (ACO) with critical ischemia of the lower limbs (Fonten stage III-IV). MATERIAL AND METHODS:Case histories of 105 ACO patients with critical ischemia of the lower limbs (mean age 65 +/- 11.8 years) were analy...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Vorob'ev PA,Dergach EV,Gerasimov VB,Avksent'eva MV

    更新日期:2001-01-01 00:00:00

  • [Cardiac changes in hereditary spinocerebellar degenerations].

    abstract::Echocardiographic alterations were compared with the clinical picture in 32 patients with different forms of hereditary spinocerebellar degenerations (HSCD). Three groups of patients were examined. Group I included patients with Friedreich's ataxia (FA), group II consisted of patients with familial cerebellar degenera...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Illarioshkin SN,Borisenko VV,Ivanova-Smolenskaia IA

    更新日期:1990-01-01 00:00:00

  • [Lyme arthritis: the joint lesions in Lyme borreliosis in the USA].

    abstract::Of 55 untreated patients with erythema migrans only 20% were free of follow-up manifestations of Lyme's disease. The rest exhibited episodes of articular, periarticular or musculoskeletal pains (18%), one or more episodes of arthritis (51%) or chronic arthritis (11%). Lyme's arthritis arises due to invasion of Borreli...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Steere AC

    更新日期:1995-01-01 00:00:00

  • [The long-term prognosis of the course of different forms of ischemic heart disease and a scale for assessing its risk of death].

    abstract::The data obtained in a prospective study made it possible, using Markov's analysis, to assess different forms of coronary heart disease (CHD) of long duration and to elaborate an unsophisticated scale for estimating individual risk of death from that disease. The Markov's analysis demonstrated a high enough probabilit...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Plavinskaia SI,Shestov DB

    更新日期:1990-01-01 00:00:00

  • [Hematosalivary mechanisms of regulation in rheumatoid arthritis].

    abstract:AIM:To study biochemical indicators of the hematosalivary barrier operation in varying activity of articular inflammation and their correlations. MATERIAL AND METHODS:Biochemical indices of mixed saliva and peripheral blood were studied in 38 healthy subjects and 99 patients with rheumatoid arthritis (RA). RESULTS:Op...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ulanova EA,Grigor'ev IV,Novikova IA

    更新日期:2001-01-01 00:00:00

  • Application of bacterial therapeutic vaccine Immunovac-VP4 in the treatment of pollinosis.

    abstract:AIM:The aim of the study was to study the effectiveness of the complex use of bacterial therapeutic vaccine Immunovac-VP4 and allergen-specific immune therapy (ASIT) in pollinosis in children and adults. MATERIALS AND METHODS:Bacterial therapeutic vaccine Immunovac-VP4 was used annually, nasal and oral administration ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/terarkh201890316-20

    authors: Kostinov MP,Poddubikova AM,Magarshak OO,Poddubikov AV

    更新日期:2018-04-19 00:00:00

  • [The state of the great arteries in type 2 diabetes mellitus patients with obstructive sleep apnea syndrome].

    abstract:AIM:To evaluate the impact of hyperglycemia concurrent with obstructive sleep apnea syndrome (OSAS) on endothelial function (EF) and vessel remodeling in patients with Grade 1-2 hypertension. MATERIAL AND METHODS:A total of 101 patients with Grade 1-2 hypertension were examined. A study group (SG) consisted of 74 hype...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh2015871026-30

    authors: Oleynikov VE,Sergatskaya NV,Gusakovskaya LI,Khromova AA

    更新日期:2015-01-01 00:00:00

  • [The new basic agent prospidin in the therapy of rheumatoid arthritis. An evaluation of the clinical effectiveness and the mechanism of action of prospidin].

    abstract::A therapeutic effect of prospidine, a Soviet antitumor drug, was studied on the basis of clinicoimmunological correlations in 74 patients with proved rheumatoid arthritis (RA) who were resistant to well known basic drugs. It was administered parenterally and intraarticularly according to the methods developed by the a...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:

    authors: Benenson EV,Nemtsov BF,Krasnov SL

    更新日期:1986-01-01 00:00:00

  • [Acute-onset nephritis in middle-aged and elderly patients].

    abstract::Ten cases of the pronounced acute nephritic syndrome among patients aged 61 to 82 years are analyzed. In 3 cases, which eventuated in lethal outcome, the diagnosis of nephritis was confirmed morphologically. The features of the course, clinical picture and differential diagnosis of acute nephritides in elderly and sen...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Borisov IA,Perov IuL,Sura VV

    更新日期:1985-01-01 00:00:00