Abstract:
:The pathogenesis of 210Po-induced tumors in the peripheral lung of Syrian golden hamsters has been studied in a serial sacrifice experiment utilizing both plastic (glycol methacrylate) and routine paraffin embedding procedures for lung sections. A rapid progression from hyperplasia of bronchiolar-type cells that appear in the alveolar region to malignant tumors was documented. Tumors began appearing as early as 15 weeks after the first intratracheal instillation of 210Po.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Kennedy AR,McGundy RB,Little JBsubject
Has Abstractpub_date
1978-04-01 00:00:00pages
1127-35issue
4eissn
0008-5472issn
1538-7445journal_volume
38pub_type
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